UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YGL043W

Length:

309

Number of sequences:

5887

Description:

YGL043W DST1 SGDID:S000003011, Chr VII from 417483-418412, Genome Release 64-1-1, Verified ORF, "General transcription elongation factor TFIIS, enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P07273	309	TFS2_YEAST Transcription elongation factor S-...	309	0	642	100	100	GO:0005634; C:nucleus; IDA:SGD.
									GO:0001139; F:core RNA polymerase II recruiting transcription factor activity; IMP:SGD.::GO:0000993; F:RNA polymerase II core binding; IPI:SGD.::GO:0001012; F:RNA polymerase II regulatory region DNA binding; IDA:SGD.::GO:0003746; F:translation elongation factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0001193; P:maintenance of transcriptional fidelity during DNA-dependent transcription elongation from RNA polymerase II promoter; IMP:SGD.::GO:0006379; P:mRNA cleavage; IDA:SGD.::GO:0045899; P:positive regulation of RNA polymerase II transcriptional preinitiation complex assembly; IMP:SGD.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IDA:SGD.::GO:0031440; P:regulation of mRNA 3'-end processing; IMP:SGD.::GO:0031564; P:transcription antitermination; IDA:SGD.::GO:0006362; P:transcription elongation from RNA polymerase I promoter; IDA:SGD.::GO:0042797; P:tRNA transcription from RNA polymerase III promoter; IMP:SGD.
2	P49373	293	TFS2_SCHPO Transcription elongation factor S-...	312	4e-54	184	35	55	GO:0005634; C:nucleus; IDA:PomBase.
									GO:0000991; F:core RNA polymerase II binding transcription factor activity; IC:PomBase.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0003746; F:translation elongation factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0002182; P:cytoplasmic translational elongation; NAS:PomBase.::GO:0006379; P:mRNA cleavage; ISS:PomBase.::GO:0032784; P:regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:InterPro.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; ISS:PomBase.
3	Q29RL9	301	TCEA1_BOVIN Transcription elongation factor A...	313	1e-37	141	33	51
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003746; F:translation elongation factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032784; P:regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006354; P:transcription elongation, DNA-dependent; IEA:InterPro.
4	P23193	301	TCEA1_HUMAN Transcription elongation factor A...	319	2e-37	140	33	50	GO:0005730; C:nucleolus; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003746; F:translation elongation factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.::GO:0032784; P:regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.::GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
5	Q4KLL0	301	TCEA1_RAT Transcription elongation factor A p...	313	3e-36	137	33	52	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003746; F:translation elongation factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032784; P:regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:InterPro.::GO:0006354; P:transcription elongation, DNA-dependent; IEA:InterPro.
6	P10711	301	TCEA1_MOUSE Transcription elongation factor A...	313	5e-36	136	33	51	GO:0005654; C:nucleoplasm; IDA:MGI.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003746; F:translation elongation factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0030218; P:erythrocyte differentiation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0032784; P:regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006354; P:transcription elongation, DNA-dependent; IEA:InterPro.
7	Q63799	299	TCEA2_RAT Transcription elongation factor A p...	302	3e-30	120	30	48	GO:0005634; C:nucleus; TAS:RGD.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003746; F:translation elongation factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0032784; P:regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006354; P:transcription elongation, DNA-dependent; IEA:InterPro.
8	Q148K0	300	TCEA2_BOVIN Transcription elongation factor A...	315	9e-30	119	30	49	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003746; F:translation elongation factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032784; P:regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:InterPro.::GO:0006354; P:transcription elongation, DNA-dependent; IEA:InterPro.
9	Q15560	299	TCEA2_HUMAN Transcription elongation factor A...	320	2e-29	118	30	46	GO:0008023; C:transcription elongation factor complex; NAS:UniProtKB.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003746; F:translation elongation factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032784; P:regulation of transcription elongation, DNA-dependent; NAS:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:InterPro.::GO:0006354; P:transcription elongation, DNA-dependent; NAS:UniProtKB.
10	Q9QVN7	299	TCEA2_MOUSE Transcription elongation factor A...	302	6e-29	117	29	48	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003746; F:translation elongation factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032784; P:regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:InterPro.::GO:0006354; P:transcription elongation, DNA-dependent; IEA:InterPro.
11	P52652	308	TFS2_CAEEL Putative transcription elongation ...	276	2e-25	107	29	53	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003746; F:translation elongation factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032784; P:regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:InterPro.::GO:0006354; P:transcription elongation, DNA-dependent; IEA:InterPro.
12	P23881	347	TCEA3_MOUSE Transcription elongation factor A...	342	2e-24	104	27	45	GO:0005634; C:nucleus; IDA:MGI.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003746; F:translation elongation factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032784; P:regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:InterPro.::GO:0006354; P:transcription elongation, DNA-dependent; IEA:InterPro.
13	P20232	313	TFS2_DROME Transcription elongation factor S-...	277	1e-23	102	29	48	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003746; F:translation elongation factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032784; P:regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:InterPro.::GO:0006354; P:transcription elongation, DNA-dependent; IEA:InterPro.
14	Q2KI09	349	TCEA3_BOVIN Transcription elongation factor A...	344	4e-23	100	26	45	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003746; F:translation elongation factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032784; P:regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:InterPro.::GO:0006354; P:transcription elongation, DNA-dependent; IEA:InterPro.
15	Q54YG9	319	TCEA1_DICDI Transcription elongation factor A...	300	2e-21	95.5	28	48	GO:0005654; C:nucleoplasm; ISS:dictyBase.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032784; P:regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:InterPro.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; ISS:dictyBase.
16	O75764	348	TCEA3_HUMAN Transcription elongation factor A...	161	4e-21	95.1	32	52	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003746; F:translation elongation factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032784; P:regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:InterPro.::GO:0006354; P:transcription elongation, DNA-dependent; IEA:InterPro.
17	P0C8F7	243	TFS2_ASFP4 Transcription factor S-II-related ...	95	0.00000001	58.2	33	58	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032784; P:regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
18	P27948	243	TFS2_ASFB7 Transcription factor S-II-related ...	95	0.00000001	58.2	33	58	GO:0005634; C:nucleus; IEA:InterPro.
									GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032784; P:regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
19	P0C8F8	243	TFS2_ASFWA Transcription factor S-II-related ...	95	0.00000001	58.2	33	58
									GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032784; P:regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
20	P0C8F6	243	TFS2_ASFM2 Transcription factor S-II-related ...	95	0.00000002	57.8	34	57
									GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032784; P:regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
21	P0C8F5	243	TFS2_ASFK5 Transcription factor S-II-related ...	95	0.00000003	57	32	58
									GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032784; P:regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
22	Q6GZP4	92	081R_FRG3G Putative transcription elongation ...	59	0.00000007	53.5	42	53
									GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.
23	Q9Y2Y1	108	RPC10_HUMAN DNA-directed RNA polymerase III s...	40	0.00001	47.8	53	70	GO:0005666; C:DNA-directed RNA polymerase III complex; TAS:ProtInc.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003899; F:DNA-directed RNA polymerase activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.::GO:0006386; P:termination of RNA polymerase III transcription; TAS:Reactome.::GO:0006385; P:transcription elongation from RNA polymerase III promoter; TAS:Reactome.
24	Q04307	110	RPC10_YEAST DNA-directed RNA polymerase III s...	34	0.00001	47.4	56	71	GO:0005666; C:DNA-directed RNA polymerase III complex; IDA:SGD.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006386; P:termination of RNA polymerase III transcription; IMP:SGD.::GO:0042797; P:tRNA transcription from RNA polymerase III promoter; IMP:SGD.
25	Q5UQS8	173	TFS2_MIMIV Transcription factor S-II-related ...	51	0.00001	48.1	47	57
									GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
26	Q9CQZ7	108	RPC10_MOUSE DNA-directed RNA polymerase III s...	39	0.00001	47.4	54	69	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.
27	Q197A5	137	VF349_IIV3 Putative transcription elongation ...	36	0.00005	45.8	50	61
									GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.
28	Q2M2S7	108	RPC10_BOVIN DNA-directed RNA polymerase III s...	39	0.00007	45.1	51	67	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.
29	Q56254	110	RPOM_THECE DNA-directed RNA polymerase subuni...	42	0.0002	43.5	40	60
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
30	P32529	125	RPA12_YEAST DNA-directed RNA polymerase I sub...	83	0.0003	43.5	34	55	GO:0005736; C:DNA-directed RNA polymerase I complex; IDA:SGD.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006363; P:termination of RNA polymerase I transcription; IMP:SGD.::GO:0042790; P:transcription of nuclear large rRNA transcript from RNA polymerase I promoter; IGI:SGD.
31	O13896	109	RPC10_SCHPO DNA-directed RNA polymerase III s...	35	0.0007	42	46	66	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005666; C:DNA-directed RNA polymerase III complex; TAS:PomBase.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003899; F:DNA-directed RNA polymerase activity; TAS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006384; P:transcription initiation from RNA polymerase III promoter; TAS:PomBase.::GO:0042779; P:tRNA 3'-trailer cleavage; IMP:PomBase.

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