Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL040C
Length:
342
Number of sequences:
5887
Description:
YGL040C HEM2 SGDID:S000003008, Chr VII from 420555-419527, Genome Release 64-1-1, reverse complement, Verified ORF, "Aminolevulinate dehydratase, a homo-octameric enzyme, catalyzes the conversion of 5-aminolevulinate to porphobilinogen, the second step in heme biosynthesis; enzymatic activity is zinc-dependent; localizes to the cytoplasm and nucleus"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P05373    342   HEM2_YEAST Delta-aminolevulinic acid dehydrat...3420     706     100     100GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0032791; F:lead ion binding; ISS:UniProtKB.::GO:0004655; F:porphobilinogen synthase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0006783; P:heme biosynthetic process; ISS:UniProtKB.
2O42768    340   HEM2_CANGA Delta-aminolevulinic acid dehydrat...3380     622     87     94
GO:0032791; F:lead ion binding; ISS:UniProtKB.::GO:0004655; F:porphobilinogen synthase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0006783; P:heme biosynthetic process; ISS:UniProtKB.
3Q750E0    340   HEM2_ASHGO Delta-aminolevulinic acid dehydrat...3370     558     81     89
GO:0032791; F:lead ion binding; ISS:UniProtKB.::GO:0004655; F:porphobilinogen synthase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0006783; P:heme biosynthetic process; ISS:UniProtKB.
4P78974    329   HEM2_SCHPO Delta-aminolevulinic acid dehydrat...3293e-128     377     57     73GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0032791; F:lead ion binding; ISS:UniProtKB.::GO:0004655; F:porphobilinogen synthase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0006783; P:heme biosynthetic process; ISS:UniProtKB.
5P13716    330   HEM2_HUMAN Delta-aminolevulinic acid dehydrat...3295e-120     356     53     68GO:0005829; C:cytosol; TAS:Reactome.
GO:0042802; F:identical protein binding; IPI:UniProtKB.::GO:0032791; F:lead ion binding; IDA:UniProtKB.::GO:0004655; F:porphobilinogen synthase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
GO:0006783; P:heme biosynthetic process; IDA:UniProtKB.::GO:0051260; P:protein homooligomerization; IPI:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
6Q5R971    330   HEM2_PONAB Delta-aminolevulinic acid dehydrat...3291e-119     355     53     68
GO:0032791; F:lead ion binding; ISS:UniProtKB.::GO:0004655; F:porphobilinogen synthase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0006783; P:heme biosynthetic process; ISS:UniProtKB.
7Q58DK5    329   HEM2_BOVIN Delta-aminolevulinic acid dehydrat...3281e-119     355     53     68
GO:0032791; F:lead ion binding; ISS:UniProtKB.::GO:0004655; F:porphobilinogen synthase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0006783; P:heme biosynthetic process; ISS:UniProtKB.
8Q60HH9    330   HEM2_MACFA Delta-aminolevulinic acid dehydrat...3292e-119     355     53     68
GO:0032791; F:lead ion binding; ISS:UniProtKB.::GO:0004655; F:porphobilinogen synthase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0006783; P:heme biosynthetic process; ISS:UniProtKB.
9P10518    330   HEM2_MOUSE Delta-aminolevulinic acid dehydrat...3291e-118     353     52     68
GO:0042802; F:identical protein binding; IPI:MGI.::GO:0032791; F:lead ion binding; ISS:UniProtKB.::GO:0004655; F:porphobilinogen synthase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0006783; P:heme biosynthetic process; ISS:UniProtKB.
10P06214    330   HEM2_RAT Delta-aminolevulinic acid dehydratas...3291e-117     350     52     68GO:0005829; C:cytosol; IDA:RGD.::GO:0005615; C:extracellular space; IDA:RGD.
GO:0032791; F:lead ion binding; ISS:UniProtKB.::GO:0004655; F:porphobilinogen synthase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0071284; P:cellular response to lead ion; IEP:RGD.::GO:0006783; P:heme biosynthetic process; ISS:UniProtKB.::GO:0014823; P:response to activity; IEP:RGD.::GO:0010044; P:response to aluminum ion; IEP:RGD.::GO:0043200; P:response to amino acid stimulus; IEP:RGD.::GO:0046685; P:response to arsenic-containing substance; IDA:RGD.::GO:0046686; P:response to cadmium ion; IDA:RGD.::GO:0032025; P:response to cobalt ion; IEP:RGD.::GO:0042493; P:response to drug; IDA:RGD.::GO:0045471; P:response to ethanol; IDA:RGD.::GO:0070542; P:response to fatty acid; IEP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0009635; P:response to herbicide; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0010212; P:response to ionizing radiation; IEP:RGD.::GO:0010039; P:response to iron ion; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IEP:RGD.::GO:0046689; P:response to mercury ion; IEP:RGD.::GO:0051597; P:response to methylmercury; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0006979; P:response to oxidative stress; IEP:RGD.::GO:0070541; P:response to platinum ion; IEP:RGD.::GO:0010269; P:response to selenium ion; IEP:RGD.::GO:0010266; P:response to vitamin B1; IEP:RGD.::GO:0033197; P:response to vitamin E; IEP:RGD.::GO:0010043; P:response to zinc ion; IDA:RGD.
11Q55E06    333   HEM2_DICDI Delta-aminolevulinic acid dehydrat...3331e-104     317     47     66
GO:0032791; F:lead ion binding; ISS:UniProtKB.::GO:0004655; F:porphobilinogen synthase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0006783; P:heme biosynthetic process; ISS:UniProtKB.
12P30950    324   HEM2_BACSU Delta-aminolevulinic acid dehydrat...3147e-82     258     45     61
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004655; F:porphobilinogen synthase activity; IEA:EC.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
13Q9K8G2    328   HEM2_BACHD Delta-aminolevulinic acid dehydrat...3258e-80     253     42     62
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004655; F:porphobilinogen synthase activity; IEA:EC.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
14P64335    324   HEM2_STAAW Delta-aminolevulinic acid dehydrat...3162e-79     252     42     62
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004655; F:porphobilinogen synthase activity; IEA:EC.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
15Q6G8Q7    324   HEM2_STAAS Delta-aminolevulinic acid dehydrat...3162e-79     252     42     62
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004655; F:porphobilinogen synthase activity; IEA:EC.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
16Q6GG37    324   HEM2_STAAR Delta-aminolevulinic acid dehydrat...3162e-79     252     42     62
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004655; F:porphobilinogen synthase activity; IEA:EC.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
17P64334    324   HEM2_STAAN Delta-aminolevulinic acid dehydrat...3162e-79     252     42     62
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004655; F:porphobilinogen synthase activity; IEA:EC.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
18P64333    324   HEM2_STAAM Delta-aminolevulinic acid dehydrat...3162e-79     252     42     62
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004655; F:porphobilinogen synthase activity; IEA:EC.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
19Q5HFA4    324   HEM2_STAAC Delta-aminolevulinic acid dehydrat...3162e-79     252     42     62
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004655; F:porphobilinogen synthase activity; IEA:EC.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
20Q2FXR3    324   HEM2_STAA8 Delta-aminolevulinic acid dehydrat...3162e-79     252     42     62
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004655; F:porphobilinogen synthase activity; IEA:EC.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
21Q8CNZ0    324   HEM2_STAES Delta-aminolevulinic acid dehydrat...3161e-78     249     43     61
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004655; F:porphobilinogen synthase activity; IEA:EC.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
22Q5HNN5    324   HEM2_STAEQ Delta-aminolevulinic acid dehydrat...3161e-78     249     43     61
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004655; F:porphobilinogen synthase activity; IEA:EC.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
23P0C1R9    323   HEM2_STAAU Delta-aminolevulinic acid dehydrat...3059e-77     245     43     62
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004655; F:porphobilinogen synthase activity; IEA:EC.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
24O67876    330   HEM2_AQUAE Delta-aminolevulinic acid dehydrat...3072e-71     231     40     62
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004655; F:porphobilinogen synthase activity; IEA:EC.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
25Q60178    335   HEM2_METJA Delta-aminolevulinic acid dehydrat...3103e-71     231     45     61
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004655; F:porphobilinogen synthase activity; IEA:EC.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
26Q02250    320   HEM2_METSC Delta-aminolevulinic acid dehydrat...3151e-70     229     40     62
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004655; F:porphobilinogen synthase activity; IEA:EC.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
27O26839    326   HEM2_METTH Delta-aminolevulinic acid dehydrat...3131e-68     224     41     61
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004655; F:porphobilinogen synthase activity; IEA:EC.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
28O28305    322   HEM2_ARCFU Delta-aminolevulinic acid dehydrat...3123e-68     223     42     61
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004655; F:porphobilinogen synthase activity; IEA:EC.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
29P43087    326   HEM2_SYNE7 Delta-aminolevulinic acid dehydrat...3152e-66     218     40     57
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004655; F:porphobilinogen synthase activity; IEA:EC.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
30O84638    338   HEM2_CHLTR Delta-aminolevulinic acid dehydrat...3164e-65     215     39     59
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004655; F:porphobilinogen synthase activity; IEA:EC.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
31Q9PLU4    333   HEM2_CHLMU Delta-aminolevulinic acid dehydrat...3139e-65     214     39     58
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004655; F:porphobilinogen synthase activity; IEA:EC.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
records
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