Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL025C
Length:
397
Number of sequences:
5887
Description:
YGL025C PGD1 SGDID:S000002993, Chr VII from 449957-448764, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for basal and activated transcription; direct target of Cyc8p-Tup1p transcriptional corepressor"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P40356    397   MED3_YEAST Mediator of RNA polymerase II tran...3970     806     100     100GO:0070847; C:core mediator complex; IDA:SGD.::GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001102; F:RNA polymerase II activating transcription factor binding; IDA:SGD.::GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.::GO:0001135; F:RNA polymerase II transcription factor recruiting transcription factor activity; IMP:SGD.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0051123; P:RNA polymerase II transcriptional preinitiation complex assembly; IMP:SGD.
2Q6FXZ4    481   MED3_CANGA Mediator of RNA polymerase II tran...1361e-25     111     43     64GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
3Q752T7    332   MED3_ASHGO Mediator of RNA polymerase II tran...3981e-17     86.7     27     42GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
4Q6CNQ9    318   MED3_KLULA Mediator of RNA polymerase II tran...3970.00000000001     68.9     24     40GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
5A2ASS6    35213   TITIN_MOUSE Titin OS=Mus musculus (Mouse). GN...750.96     35.8     32     51GO:0031430; C:M band; IDA:MGI.::GO:0005859; C:muscle myosin complex; TAS:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IDA:MGI.
GO:0030506; F:ankyrin binding; IPI:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005200; F:structural constituent of cytoskeleton; TAS:MGI.
GO:0007512; P:adult heart development; IMP:MGI.::GO:0055003; P:cardiac myofibril assembly; IMP:MGI.::GO:0043056; P:forward locomotion; IMP:MGI.::GO:0003007; P:heart morphogenesis; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0006936; P:muscle contraction; IMP:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0045214; P:sarcomere organization; IMP:MGI.::GO:0001756; P:somitogenesis; IEP:BHF-UCL.
6Q8WZ42    34350   TITIN_HUMAN Titin OS=Homo sapiens (Human). GN...751.3     35.4     32     51GO:0000794; C:condensed nuclear chromosome; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005576; C:extracellular region; TAS:Reactome.::GO:0031430; C:M band; IDA:BHF-UCL.::GO:0005865; C:striated muscle thin filament; IDA:BHF-UCL.::GO:0030018; C:Z disc; IDA:UniProtKB.
GO:0051015; F:actin filament binding; IDA:BHF-UCL.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IDA:BHF-UCL.::GO:0005516; F:calmodulin binding; TAS:UniProtKB.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0051371; F:muscle alpha-actinin binding; IPI:BHF-UCL.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0002020; F:protease binding; IPI:UniProtKB.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0043621; F:protein self-association; IDA:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0008307; F:structural constituent of muscle; TAS:UniProtKB.::GO:0031433; F:telethonin binding; ISS:BHF-UCL.
GO:0048739; P:cardiac muscle fiber development; IMP:BHF-UCL.::GO:0055008; P:cardiac muscle tissue morphogenesis; IMP:BHF-UCL.::GO:0055003; P:cardiac myofibril assembly; IMP:BHF-UCL.::GO:0007076; P:mitotic chromosome condensation; IEP:BHF-UCL.::GO:0030049; P:muscle filament sliding; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0002576; P:platelet degranulation; TAS:Reactome.::GO:0045859; P:regulation of protein kinase activity; IMP:BHF-UCL.::GO:0051592; P:response to calcium ion; IDA:BHF-UCL.::GO:0045214; P:sarcomere organization; IMP:BHF-UCL.::GO:0048769; P:sarcomerogenesis; IMP:BHF-UCL.::GO:0030241; P:skeletal muscle myosin thick filament assembly; IMP:BHF-UCL.::GO:0030240; P:skeletal muscle thin filament assembly; IMP:BHF-UCL.::GO:0006941; P:striated muscle contraction; TAS:UniProtKB.
7Q54XM9    450   TAF11_DICDI Transcription initiation factor T...809.3     32     28     50GO:0005669; C:transcription factor TFIID complex; ISS:dictyBase.
GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; ISS:dictyBase.
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