Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL023C
Length:
635
Number of sequences:
5887
Description:
YGL023C PIB2 SGDID:S000002991, Chr VII from 452104-450197, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein binding phosphatidylinositol 3-phosphate, involved in telomere-proximal repression of gene expression; similar to Fab1 and Vps27"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q7Z6J4    655   FGD2_HUMAN FYVE, RhoGEF and PH domain-contain...360.008     43.1     42     53GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0031267; F:small GTPase binding; ISS:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
92Q3TB82    279   PKHF1_MOUSE Pleckstrin homology domain-contai...450.009     42     40     56GO:0005764; C:lysosome; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IDA:MGI.
93A4QTV1    713   VPS27_MAGO7 Vacuolar protein sorting-associat...260.009     42.7     58     62GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0043581; P:mycelium development; IEP:PAMGO_MGG.
94Q9JJ50    776   HGS_RAT Hepatocyte growth factor-regulated ty...250.009     42.7     56     60GO:0005829; C:cytosol; IDA:RGD.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0032585; C:multivesicular body membrane; IEA:UniProtKB-SubCell.::GO:0030141; C:secretory granule; IDA:RGD.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; NAS:RGD.
GO:0008333; P:endosome to lysosome transport; IMP:RGD.::GO:0006886; P:intracellular protein transport; IEA:InterPro.
95Q99LI8    775   HGS_MOUSE Hepatocyte growth factor-regulated ...250.009     42.7     56     60GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0032585; C:multivesicular body membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
96Q8BY35    655   FGD2_MOUSE FYVE, RhoGEF and PH domain-contain...360.01     42.7     42     53GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
97Q68FU1    279   PKHF1_RAT Pleckstrin homology domain-containi...450.01     42     40     56GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
98Q06651    286   PIB1_YEAST E3 ubiquitin-protein ligase PIB1 O...340.011     42     47     59GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0005770; C:late endosome; IDA:SGD.
GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:SGD.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
99P0CS26    750   VPS27_CRYNJ Vacuolar protein sorting-associat...440.015     42.4     43     55GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
100P0CS27    750   VPS27_CRYNB Vacuolar protein sorting-associat...440.015     42.4     43     55GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
101Q0CJV3    556   VPS27_ASPTN Vacuolar protein sorting-associat...330.024     41.2     48     64GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
102Q80Y56    783   RBNS5_MOUSE Rabenosyn-5 OS=Mus musculus (Mous...350.04     40.8     40     54GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0017137; F:Rab GTPase binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
103Q7RZJ2    724   VPS27_NEUCR Vacuolar protein sorting-associat...530.045     40.4     40     53GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
104Q9H1K0    784   RBNS5_HUMAN Rabenosyn-5 OS=Homo sapiens (Huma...350.045     40.4     40     54GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0016197; P:endosome transport; NAS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
105Q810B6    1169   ANFY1_MOUSE Ankyrin repeat and FYVE domain-co...330.045     40.8     42     55GO:0010008; C:endosome membrane; IDA:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; NAS:UniProtKB.
106O13786    536   PEP7_SCHPO Vacuolar segregation protein pep7 ...800.13     38.9     29     39GO:0005794; C:Golgi apparatus; IDA:PomBase.
GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006896; P:Golgi to vacuole transport; ISS:PomBase.::GO:0006904; P:vesicle docking involved in exocytosis; ISS:PomBase.::GO:0006906; P:vesicle fusion; ISS:PomBase.
107Q22712    1006   MTMR3_CAEEL Myotublarin-related protein 3 OS=...810.068     40     30     46
GO:0016312; F:inositol bisphosphate phosphatase activity; IDA:WormBase.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0034594; F:phosphatidylinositol trisphosphate phosphatase activity; IDA:WormBase.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0040002; P:collagen and cuticulin-based cuticle development; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0046855; P:inositol phosphate dephosphorylation; IDA:WormBase.::GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0045807; P:positive regulation of endocytosis; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040017; P:positive regulation of locomotion; IMP:WormBase.::GO:0046662; P:regulation of oviposition; IMP:WormBase.
108Q9P2R3    1169   ANFY1_HUMAN Ankyrin repeat and FYVE domain-co...260.072     40     50     58GO:0010008; C:endosome membrane; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
109Q2GS33    737   VPS27_CHAGB Vacuolar protein sorting-associat...260.076     40     54     62GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
110Q80UZ0    1219   FGD5_MOUSE FYVE, RhoGEF and PH domain-contain...760.11     39.7     28     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
111Q6ZNL6    1462   FGD5_HUMAN FYVE, RhoGEF and PH domain-contain...830.11     39.7     29     41GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0031267; F:small GTPase binding; ISS:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.
112Q54IL5    1697   UGT52_DICDI UDP-sugar-dependent glycosyltrans...390.16     38.9     44     54
GO:0051507; F:beta-sitosterol UDP-glucosyltransferase activity; IDA:dictyBase.::GO:0030246; F:carbohydrate binding; IEA:InterPro.::GO:0051505; F:cholesterol UDP-glucosyltransferase activity; IDA:dictyBase.::GO:0051506; F:ergosterol UDP-glucosyltransferase activity; IDA:dictyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0051508; F:stigmasterol UDP-glucosyltransferase activity; IDA:dictyBase.::GO:0051509; F:tomatidine UDP-glucosyltransferase activity; IDA:dictyBase.
GO:0030259; P:lipid glycosylation; IEA:InterPro.::GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
113Q6CFT4    565   VPS27_YARLI Vacuolar protein sorting-associat...750.16     38.9     29     45GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
114Q5JSP0    725   FGD3_HUMAN FYVE, RhoGEF and PH domain-contain...320.35     37.7     38     69GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0031267; F:small GTPase binding; ISS:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
115Q5R5T1    737   FGD3_PONAB FYVE, RhoGEF and PH domain-contain...320.47     37.4     38     69GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
116P52734    960   FGD1_MOUSE FYVE, RhoGEF and PH domain-contain...680.64     37     28     46GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0001726; C:ruffle; IDA:MGI.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0008360; P:regulation of cell shape; IDA:UniProtKB.
117P98174    961   FGD1_HUMAN FYVE, RhoGEF and PH domain-contain...681.1     36.2     26     46GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0001726; C:ruffle; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0031267; F:small GTPase binding; IDA:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0046847; P:filopodium assembly; IDA:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0043088; P:regulation of Cdc42 GTPase activity; IDA:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
118A8XXC7    417   WDFY2_CAEBR WD repeat and FYVE domain-contain...454     33.9     33     49
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
119Q0SGS7    112   CLPS_RHOSR ATP-dependent Clp protease adapter...1074.1     32.3     28     43
GO:0030163; P:protein catabolic process; IEA:InterPro.
120Q18964    415   WDFY2_CAEEL WD repeat and FYVE domain-contain...454.3     33.9     33     49
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:WormBase.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006897; P:endocytosis; IMP:WormBase.
121C1AVW7    112   CLPS_RHOOB ATP-dependent Clp protease adapter...1075     32     29     43
GO:0030163; P:protein catabolic process; IEA:InterPro.
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