rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | Q8K296 | 1196 | MTMR3_MOUSE Myotubularin-related protein 3 OS... | 34 | 0.0002 | 48.1 | 50 | 62 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; ISS:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:UniProtKB. | 62 | Q91ZT5 | 766 | FGD4_MOUSE FYVE, RhoGEF and PH domain-contain... | 148 | 0.0003 | 47.8 | 26 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030175; C:filopodium; IDA:MGI.::GO:0030027; C:lamellipodium; IDA:MGI. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0030032; P:lamellipodium assembly; IDA:MGI.::GO:0030035; P:microspike assembly; IDA:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 63 | Q54LD5 | 785 | ADCD_DICDI Arrestin domain-containing protein... | 50 | 0.0003 | 47.8 | 42 | 54 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 64 | Q9BQ24 | 234 | ZFY21_HUMAN Zinc finger FYVE domain-containin... | 35 | 0.0003 | 46.2 | 46 | 51 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 65 | Q05B78 | 254 | ZFY21_BOVIN Zinc finger FYVE domain-containin... | 51 | 0.0004 | 46.2 | 37 | 47 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 66 | Q5ZLY5 | 249 | PKHF2_CHICK Pleckstrin homology domain-contai... | 97 | 0.0005 | 45.8 | 32 | 43 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 67 | Q9NYA4 | 1195 | MTMR4_HUMAN Myotubularin-related protein 4 OS... | 34 | 0.0005 | 47 | 47 | 68 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | | 68 | Q91XS1 | 1190 | MTMR4_MOUSE Myotubularin-related protein 4 OS... | 34 | 0.0007 | 46.6 | 47 | 68 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 69 | Q7ZXF1 | 1078 | MTMR4_XENLA Myotubularin-related protein 4 OS... | 34 | 0.0007 | 46.6 | 47 | 68 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 70 | Q91WB4 | 249 | PKHF2_MOUSE Pleckstrin homology domain-contai... | 97 | 0.0008 | 45.1 | 32 | 44 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 71 | Q8VCM3 | 234 | ZFY21_MOUSE Zinc finger FYVE domain-containin... | 34 | 0.001 | 44.7 | 47 | 53 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 72 | Q5BBK9 | 715 | VPS27_EMENI Vacuolar protein sorting-associat... | 33 | 0.001 | 45.8 | 52 | 67 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 73 | Q0U4Z8 | 720 | VPS27_PHANO Vacuolar protein sorting-associat... | 25 | 0.001 | 45.8 | 56 | 68 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 74 | D3ZVP7 | 234 | ZFY21_RAT Zinc finger FYVE domain-containing ... | 34 | 0.001 | 44.3 | 47 | 53 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 75 | Q9HBF4 | 777 | ZFYV1_HUMAN Zinc finger FYVE domain-containin... | 35 | 0.73 | 36.6 | 46 | 60 | GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB.::GO:0005795; C:Golgi stack; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; IDA:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; NAS:UniProtKB. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB. | 76 | Q5RFL4 | 789 | ZFYV1_PONAB Zinc finger FYVE domain-containin... | 35 | 0.78 | 36.6 | 46 | 60 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 77 | Q9H8W4 | 249 | PKHF2_HUMAN Pleckstrin homology domain-contai... | 43 | 0.002 | 44.3 | 44 | 58 | GO:0030133; C:transport vesicle; IDA:LIFEdb. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 78 | A1DFP5 | 729 | VPS27_NEOFI Vacuolar protein sorting-associat... | 33 | 0.002 | 45.1 | 52 | 67 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 79 | A1CEK1 | 714 | VPS27_ASPCL Vacuolar protein sorting-associat... | 33 | 0.002 | 45.1 | 45 | 61 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 80 | Q4WHN8 | 729 | VPS27_ASPFU Vacuolar protein sorting-associat... | 33 | 0.002 | 45.1 | 52 | 67 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 81 | P34657 | 266 | YOTB_CAEEL Uncharacterized protein ZK632.12 O... | 35 | 0.002 | 43.9 | 46 | 63 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:WormBase.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 82 | A2QWA2 | 703 | VPS27_ASPNC Vacuolar protein sorting-associat... | 33 | 0.002 | 44.7 | 52 | 64 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 83 | P32609 | 515 | PEP7_YEAST Vacuolar segregation protein PEP7 ... | 36 | 0.003 | 44.3 | 47 | 53 | GO:0010009; C:external side of endosome membrane; IDA:SGD.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006895; P:Golgi to endosome transport; IMP:SGD.::GO:0006896; P:Golgi to vacuole transport; IPI:SGD.::GO:0000011; P:vacuole inheritance; IMP:SGD.::GO:0006904; P:vesicle docking involved in exocytosis; IMP:SGD.::GO:0006906; P:vesicle fusion; IMP:SGD. | 84 | Q810J8 | 777 | ZFYV1_MOUSE Zinc finger FYVE domain-containin... | 35 | 0.71 | 36.6 | 46 | 60 | GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0005795; C:Golgi stack; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 85 | Q8VDC1 | 1437 | FYCO1_MOUSE FYVE and coiled-coil domain-conta... | 38 | 0.004 | 44.3 | 39 | 58 | GO:0005776; C:autophagic vacuole; ISS:UniProtKB.::GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:InterPro.::GO:0005770; C:late endosome; ISS:UniProtKB.::GO:0005764; C:lysosome; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0072383; P:plus-end-directed vesicle transport along microtubule; ISS:UniProtKB. | 86 | Q0V8S0 | 777 | HGS_BOVIN Hepatocyte growth factor-regulated ... | 25 | 0.004 | 43.9 | 56 | 60 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0032585; C:multivesicular body membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 87 | Q96S99 | 279 | PKHF1_HUMAN Pleckstrin homology domain-contai... | 47 | 0.005 | 42.7 | 38 | 55 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. | 88 | O14964 | 777 | HGS_HUMAN Hepatocyte growth factor-regulated ... | 25 | 0.005 | 43.5 | 56 | 60 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0032585; C:multivesicular body membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB. | | | | | | | | | | GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0046426; P:negative regulation of JAK-STAT cascade; IDA:HGNC.::GO:0042176; P:regulation of protein catabolic process; TAS:HGNC. | 89 | Q960X8 | 760 | HRS_DROME Hepatocyte growth factor-regulated ... | 25 | 0.006 | 43.5 | 56 | 64 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0033565; C:ESCRT-0 complex; IDA:FlyBase.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0008021; C:synaptic vesicle; NAS:FlyBase. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0006897; P:endocytosis; IMP:FlyBase.::GO:0016197; P:endosome transport; TAS:FlyBase.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; NAS:FlyBase.::GO:0045752; P:positive regulation of Toll signaling pathway; IMP:FlyBase.::GO:0016082; P:synaptic vesicle priming; NAS:FlyBase.::GO:0008293; P:torso signaling pathway; NAS:FlyBase.::GO:0016050; P:vesicle organization; NAS:FlyBase. | 90 | Q9HGN5 | 279 | YO45_SCHPO Putative E3 ubiquitin-protein liga... | 34 | 0.007 | 42.4 | 47 | 59 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000329; C:fungal-type vacuole membrane; ISS:PomBase.::GO:0005770; C:late endosome; ISS:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:PomBase.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 91 | Q7Z6J4 | 655 | FGD2_HUMAN FYVE, RhoGEF and PH domain-contain... | 36 | 0.008 | 43.1 | 42 | 53 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0031267; F:small GTPase binding; ISS:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. |