Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL023C
Length:
635
Number of sequences:
5887
Description:
YGL023C PIB2 SGDID:S000002991, Chr VII from 452104-450197, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein binding phosphatidylinositol 3-phosphate, involved in telomere-proximal repression of gene expression; similar to Fab1 and Vps27"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P53191    635   PIB2_YEAST Phosphatidylinositol 3-phosphate-b...6350     1311     100     100GO:0005770; C:late endosome; TAS:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
2Q9Y7M3    293   YNT3_SCHPO FYVE-type zinc finger-containing p...2030.000000000005     70.5     26     41GO:0000324; C:fungal-type vacuole; IDA:PomBase.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
3B4IC49    975   LST2_DROSE Lateral signaling target protein 2...530.0000000002     67.8     45     62
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
4B4PRU6    984   LST2_DROYA Lateral signaling target protein 2...530.0000000002     67.4     45     62
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
5Q9VB70    989   LST2_DROME Lateral signaling target protein 2...530.0000000002     67.4     45     62
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
6B3P851    981   LST2_DROER Lateral signaling target protein 2...530.0000000003     67.4     45     62
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
7Q6CL17    603   VPS27_KLULA Vacuolar protein sorting-associat...1530.000000002     64.3     33     44GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
8P40343    622   VPS27_YEAST Vacuolar protein sorting-associat...960.000000003     63.9     35     51GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0033565; C:ESCRT-0 complex; IPI:SGD.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0045324; P:late endosome to vacuole transport; IMP:SGD.::GO:0045053; P:protein retention in Golgi apparatus; IMP:SGD.::GO:0006623; P:protein targeting to vacuole; IMP:SGD.
9B4K982    1051   LST2_DROMO Lateral signaling target protein 2...540.000000007     62.8     41     59GO:0016020; C:membrane; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009405; P:pathogenesis; IEA:InterPro.
10B4M140    1052   LST2_DROVI Lateral signaling target protein 2...420.00000001     61.6     50     64
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
11B4NFJ7    993   LST2_DROWI Lateral signaling target protein 2...420.00000002     61.2     50     62
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
12B3MT31    985   LST2_DROAN Lateral signaling target protein 2...340.00000002     61.2     56     68
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
13A3LX75    732   VPS27_PICST Vacuolar protein sorting-associat...1270.00000002     60.8     29     48GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
14B4JHI7    1115   LST2_DROGR Lateral signaling target protein 2...420.00000003     60.5     50     64
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
15Q6BSD6    732   VPS27_DEBHA Vacuolar protein sorting-associat...870.00000004     60.1     34     47GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
16B4G2G5    1009   LST2_DROPE Lateral signaling target protein 2...340.00000004     60.5     56     68
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
17A0JMD2    969   LST2_DANRE Lateral signaling target protein 2...410.00000005     60.1     56     63GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0031901; C:early endosome membrane; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB.
GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; ISS:UniProtKB.
18Q5ABD9    841   VPS27_CANAL Vacuolar protein sorting-associat...810.00000006     59.7     33     49GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0009405; P:pathogenesis; IMP:CGD.
19Q755J9    604   VPS27_ASHGO Vacuolar protein sorting-associat...1130.0000001     58.2     33     44GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
20O59722    1932   FAB1_SCHPO 1-phosphatidylinositol 3-phosphate...940.0000002     58.5     32     46GO:0000329; C:fungal-type vacuole membrane; ISS:PomBase.
GO:0000285; F:1-phosphatidylinositol-3-phosphate 5-kinase activity; IDA:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:PomBase.
GO:0044267; P:cellular protein metabolic process; IEA:InterPro.::GO:0006995; P:cellular response to nitrogen starvation; IMP:PomBase.::GO:0006886; P:intracellular protein transport; IC:PomBase.::GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; IMP:PomBase.::GO:0007033; P:vacuole organization; ISS:PomBase.::GO:0016192; P:vesicle-mediated transport; IGI:PomBase.
21Q96T51    708   RUFY1_HUMAN RUN and FYVE domain-containing pr...430.0000002     58.2     51     63GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
22Q5R5R4    606   RUFY2_PONAB RUN and FYVE domain-containing pr...340.0000002     57.8     53     74GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
23Q54TC3    585   SLOB1_DICDI Probable inactive serine/threonin...770.0000002     57.4     38     48
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IEA:InterPro.
24Q6FQJ1    603   VPS27_CANGA Vacuolar protein sorting-associat...1110.0000002     57.4     32     44GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
25Q69ZL1    1399   FGD6_MOUSE FYVE, RhoGEF and PH domain-contain...810.0000003     57.8     33     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
26Q8WXA3    655   RUFY2_HUMAN RUN and FYVE domain-containing pr...340.0000004     57     53     74GO:0005634; C:nucleus; IDA:HPA.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
27Q8BIJ7    712   RUFY1_MOUSE RUN and FYVE domain-containing pr...430.0000004     57     49     63GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008565; F:protein transporter activity; IDA:MGI.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0030100; P:regulation of endocytosis; IDA:MGI.
28Q6ZPK7    905   LST2_MOUSE Lateral signaling target protein 2...410.0000004     57     51     59GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0031901; C:early endosome membrane; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB.
GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; ISS:UniProtKB.
29Q8R4C2    606   RUFY2_MOUSE RUN and FYVE domain-containing pr...340.0000005     56.6     53     71GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
30Q0P4S0    951   LST2_XENTR Lateral signaling target protein 2...410.0000005     56.6     51     61GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0031901; C:early endosome membrane; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB.
GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; ISS:UniProtKB.
31Q9HCC9    887   LST2_HUMAN Lateral signaling target protein 2...410.0000006     56.6     51     59GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0031901; C:early endosome membrane; IDA:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IMP:UniProtKB.
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