Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL011C
Length:
252
Number of sequences:
5887
Description:
YGL011C SCL1 SGDID:S000002979, Chr VII from 475247-474489, Genome Release 64-1-1, reverse complement, Verified ORF, "Alpha 1 subunit of the 20S proteasome involved in the degradation of ubiquitinated substrates; 20S proteasome is the core complex of the 26S proteasome; essential for growth; detected in the mitochondria"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61O70435    255   PSA3_MOUSE Proteasome subunit alpha type-3 OS...1733e-29     115     36     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0005515; F:protein binding; IPI:MGI.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
62O82530    249   PSA4_PETHY Proteasome subunit alpha type-4 OS...2383e-29     115     32     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
63P25788    255   PSA3_HUMAN Proteasome subunit alpha type-3 OS...1735e-29     115     36     53GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
64Q58DU5    255   PSA3_BOVIN Proteasome subunit alpha type-3 OS...1736e-29     115     36     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
65P18422    255   PSA3_RAT Proteasome subunit alpha type-3 OS=R...1736e-29     115     36     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
66O24616    250   PSA7B_ARATH Proteasome subunit alpha type-7-B...2248e-29     114     33     51GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.::GO:0005773; C:vacuole; IDA:TAIR.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:TAIR.
67Q9XZG5    246   PSA5_TRYBB Proteasome subunit alpha type-5 OS...1711e-28     114     36     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
68Q54DM7    232   PSA2_DICDI Proteasome subunit alpha type-2 OS...2251e-28     114     29     54GO:0005737; C:cytoplasm; IPI:dictyBase.::GO:0005634; C:nucleus; IPI:dictyBase.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
69Q0J006    249   PSA7B_ORYSJ Proteasome subunit alpha type-7-B...2361e-28     114     33     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
70A2Z3I9    249   PSA7B_ORYSI Proteasome subunit alpha type-7-B...2361e-28     114     33     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
71Q975G5    242   PSA_SULTO Proteasome subunit alpha OS=Sulfolo...2301e-28     114     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
72P21242    288   PSA3_YEAST Proteasome component C1 OS=Sacchar...1752e-28     114     37     51GO:0005739; C:mitochondrion; IC:SGD.::GO:0042175; C:nuclear outer membrane-endoplasmic reticulum membrane network; IC:SGD.::GO:0005634; C:nucleus; IC:SGD.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IDA:SGD.::GO:0034515; C:proteasome storage granule; IDA:SGD.
GO:0003729; F:mRNA binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:SGD.::GO:0010499; P:proteasomal ubiquitin-independent protein catabolic process; IDA:SGD.
73Q10KF0    235   PSA2_ORYSJ Proteasome subunit alpha type-2 OS...2352e-28     113     29     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
74A2YVR7    235   PSA2_ORYSI Proteasome subunit alpha type-2 OS...2352e-28     113     29     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
75Q9YC01    258   PSA_AERPE Proteasome subunit alpha OS=100138 ...1762e-28     113     36     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
76O73672    234   PSA2_CARAU Proteasome subunit alpha type-2 OS...2402e-28     112     32     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
77Q9V2V6    252   PSA1_HALVD Proteasome subunit alpha 1 OS=1474...2473e-28     113     35     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IDA:UniProtKB.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0010498; P:proteasomal protein catabolic process; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
78Q4JB24    242   PSA_SULAC Proteasome subunit alpha OS=NBRC 15...2434e-28     112     30     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
79P30186    250   PSA7A_ARATH Proteasome subunit alpha type-7-A...2244e-28     112     32     51GO:0009507; C:chloroplast; IDA:TAIR.::GO:0022626; C:cytosolic ribosome; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0009524; C:phragmoplast; IDA:TAIR.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.::GO:0005819; C:spindle; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
80A7I9C7    240   PSA_METB6 Proteasome subunit alpha OS=Methano...1634e-28     112     39     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
81Q8X077    249   PSA2_NEUCR Probable proteasome subunit alpha ...2329e-28     111     31     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
82Q5RDH8    248   PSA7_PONAB Proteasome subunit alpha type-7 OS...2331e-27     111     31     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
83Q9PVY6    248   PSA7A_XENLA Proteasome subunit alpha type-7-A...2371e-27     111     32     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
84Q6YT00    249   PSA7A_ORYSJ Proteasome subunit alpha type-7-A...2362e-27     110     32     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
85A2YXU2    249   PSA7A_ORYSI Proteasome subunit alpha type-7-A...2362e-27     110     32     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
86Q9PVQ1    247   PSA7B_XENLA Proteasome subunit alpha type-7-B...2372e-27     110     32     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
87P25787    234   PSA2_HUMAN Proteasome subunit alpha type-2 OS...2402e-27     110     30     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0009615; P:response to virus; IEP:UniProtKB.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
88Q3T0Y5    234   PSA2_BOVIN Proteasome subunit alpha type-2 OS...2402e-27     110     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
89O23708    235   PSA2A_ARATH Proteasome subunit alpha type-2-A...2382e-27     110     29     50GO:0022626; C:cytosolic ribosome; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0010043; P:response to zinc ion; IEP:TAIR.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
90P48004    254   PSA7_RAT Proteasome subunit alpha type-7 OS=R...2392e-27     110     31     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
91P49722    234   PSA2_MOUSE Proteasome subunit alpha type-2 OS...2402e-27     110     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
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