Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL011C
Length:
252
Number of sequences:
5887
Description:
YGL011C SCL1 SGDID:S000002979, Chr VII from 475247-474489, Genome Release 64-1-1, reverse complement, Verified ORF, "Alpha 1 subunit of the 20S proteasome involved in the degradation of ubiquitinated substrates; 20S proteasome is the core complex of the 26S proteasome; essential for growth; detected in the mitochondria"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151P92188    265   PSA1_TRYCR Proteasome subunit alpha type-1 OS...1764e-22     96.3     34     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
152O23712    277   PSA1B_ARATH Proteasome subunit alpha type-1-B...2346e-22     95.9     31     49GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
153Q55G04    241   PSA5_DICDI Proteasome subunit alpha type-5 OS...2257e-22     95.1     26     48GO:0005737; C:cytoplasm; IPI:dictyBase.::GO:0005634; C:nucleus; IPI:dictyBase.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
154P40303    254   PSA7_YEAST Proteasome component PRE6 OS=Sacch...2449e-22     95.1     28     50GO:0005739; C:mitochondrion; IDA:SGD.::GO:0042175; C:nuclear outer membrane-endoplasmic reticulum membrane network; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IDA:SGD.::GO:0034515; C:proteasome storage granule; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:SGD.::GO:0010499; P:proteasomal ubiquitin-independent protein catabolic process; IDA:SGD.
155Q94561    247   PSA5_ENTHI Proteasome subunit alpha type-5 OS...2461e-21     94.7     27     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
156Q9LSU0    249   PSA3_ORYSJ Proteasome subunit alpha type-3 OS...1741e-21     94.7     32     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
157Q5REN2    263   PSA1_PONAB Proteasome subunit alpha type-1 OS...2431e-21     94.7     27     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
158P25786    263   PSA1_HUMAN Proteasome subunit alpha type-1 OS...2272e-21     94.4     27     50GO:0005813; C:centrosome; IDA:HPA.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005844; C:polysome; TAS:ProtInc.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; TAS:ProtInc.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.::GO:0016032; P:viral reproduction; TAS:Reactome.
159Q4R3H2    263   PSA1_MACFA Proteasome subunit alpha type-1 OS...2272e-21     94.4     27     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
160Q3T0X5    263   PSA1_BOVIN Proteasome subunit alpha type-1 OS...2272e-21     94     27     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
161Q9R1P4    263   PSA1_MOUSE Proteasome subunit alpha type-1 OS...2273e-21     94     27     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0001530; F:lipopolysaccharide binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0002862; P:negative regulation of inflammatory response to antigenic stimulus; IMP:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
162P34066    278   PSA1A_ARATH Proteasome subunit alpha type-1-A...2123e-21     94     30     49GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0046685; P:response to arsenic-containing substance; IMP:TAIR.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
163Q27575    252   PSA73_DROME Proteasome subunit alpha type-7-1...2203e-21     93.6     30     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
164P18420    263   PSA1_RAT Proteasome subunit alpha type-1 OS=R...2271e-20     92     26     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
165O44156    260   PSA1_CAEEL Proteasome subunit alpha type-1 OS...2391e-20     92     28     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
166Q09583    250   PSA3_CAEEL Proteasome subunit alpha type-3 OS...1852e-20     91.3     31     50GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
167O42265    260   PSA1_CHICK Proteasome subunit alpha type-1 OS...2455e-20     90.1     27     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
168O14250    272   PSA1_SCHPO Probable proteasome subunit alpha ...2316e-20     90.1     29     50GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0019773; C:proteasome core complex, alpha-subunit complex; ISS:PomBase.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; NAS:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.
169Q9V2V5    249   PSA2_HALVD Proteasome subunit alpha 2 OS=1474...1758e-20     89.4     30     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IDA:UniProtKB.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0010498; P:proteasomal protein catabolic process; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
170O16812    245   PSA73_DROVI Proteasome subunit alpha type-7-1...1743e-19     87.8     32     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
171P32379    260   PSA5_YEAST Proteasome component PUP2 OS=Sacch...1846e-19     87     28     48GO:0005739; C:mitochondrion; IC:SGD.::GO:0042175; C:nuclear outer membrane-endoplasmic reticulum membrane network; IC:SGD.::GO:0005634; C:nucleus; IC:SGD.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IDA:SGD.::GO:0034515; C:proteasome storage granule; IDA:SGD.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:SGD.::GO:0010499; P:proteasomal ubiquitin-independent protein catabolic process; IDA:SGD.
172P52428    270   PSA1_ORYSJ Proteasome subunit alpha type-1 OS...2397e-19     87     28     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
173Q8SRU3    232   PSA5_ENCCU Probable proteasome subunit alpha ...1820.000000000000001     77     29     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
174P40302    234   PSA1_YEAST Proteasome component PRE5 OS=Sacch...2260.00000000003     64.3     26     43GO:0005739; C:mitochondrion; IC:SGD.::GO:0042175; C:nuclear outer membrane-endoplasmic reticulum membrane network; IC:SGD.::GO:0005634; C:nucleus; IC:SGD.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IDA:SGD.::GO:0034515; C:proteasome storage granule; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:SGD.::GO:0010499; P:proteasomal ubiquitin-independent protein catabolic process; IDA:SGD.
175Q8SRU7    232   PSA4_ENCCU Probable proteasome subunit alpha ...1750.00000000008     63.5     28     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
176Q2NI68    205   PSB_METST Proteasome subunit beta OS=Methanos...1720.000004     50.1     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
177Q8SQP9    242   PSA3_ENCCU Probable proteasome subunit alpha ...2140.00003     47.8     24     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
178O27270    210   PSB_METTH Proteasome subunit beta OS=thermoau...2070.00008     46.2     26     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
179D3E0A3    207   PSB_METRM Proteasome subunit beta OS=13430 / ...2030.0002     44.7     24     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
180Q18GX3    243   PSB_HALWD Proteasome subunit beta OS=Haloquad...2390.001     42.7     23     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
181Q8PZ04    210   PSB_METMA Proteasome subunit beta OS=JCM 1183...1910.002     42.4     23     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005839; C:proteasome core complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
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