UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YGL009C

Length:

779

Number of sequences:

5887

Description:

YGL009C LEU1 SGDID:S000002977, Chr VII from 478652-476313, Genome Release 64-1-1, reverse complement, Verified ORF, "Isopropylmalate isomerase, catalyzes the second step in the leucine biosynthesis pathway"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P07264	779	LEUC_YEAST 3-isopropylmalate dehydratase OS=S...	779	0	1615	100	100	GO:0009316; C:3-isopropylmalate dehydratase complex; IEA:InterPro.::GO:0005625; C:soluble fraction; IDA:SGD.
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
2	Q74ZM9	776	LEUC_ASHGO 3-isopropylmalate dehydratase OS=Y...	758	0	1168	75	85	GO:0009316; C:3-isopropylmalate dehydratase complex; IEA:InterPro.
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
3	Q00464	770	LEUC_CANMA 3-isopropylmalate dehydratase OS=C...	779	0	1122	72	82	GO:0009316; C:3-isopropylmalate dehydratase complex; IEA:InterPro.
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
4	P55251	755	LEUC_RHIPU 3-isopropylmalate dehydratase OS=R...	775	0	986	64	76	GO:0009316; C:3-isopropylmalate dehydratase complex; IEA:InterPro.
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
5	O14289	758	LEUC_SCHPO 3-isopropylmalate dehydratase OS=S...	745	0	953	64	77	GO:0009316; C:3-isopropylmalate dehydratase complex; IEA:InterPro.
									GO:0003861; F:3-isopropylmalate dehydratase activity; ISS:PomBase.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; ISS:PomBase.
6	P18250	744	LEUC_PHYBL 3-isopropylmalate dehydratase OS=P...	748	0	931	63	75	GO:0009316; C:3-isopropylmalate dehydratase complex; IEA:InterPro.
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
7	P55811	750	LEUC_RHINI 3-isopropylmalate dehydratase OS=R...	749	0	917	61	74	GO:0009316; C:3-isopropylmalate dehydratase complex; IEA:InterPro.
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
8	P49601	773	LEUC_USTMA 3-isopropylmalate dehydratase OS=U...	752	0	897	60	74	GO:0009316; C:3-isopropylmalate dehydratase complex; IEA:InterPro.
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
9	P17279	644	LEUC_MUCCL 3-isopropylmalate dehydratase OS=l...	603	0	793	65	77
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
10	Q1H0L4	468	LEUC_METFK 3-isopropylmalate dehydratase larg...	470	0	647	67	79
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
11	B8GQD6	470	LEUC_THISH 3-isopropylmalate dehydratase larg...	470	0	645	66	79
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
12	Q4FP15	467	LEUC_PELUB 3-isopropylmalate dehydratase larg...	472	0	645	65	79
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
13	A7HT10	473	LEUC_PARL1 3-isopropylmalate dehydratase larg...	476	0	643	66	77
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
14	A4G4F5	466	LEUC_HERAR 3-isopropylmalate dehydratase larg...	470	0	641	65	78
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
15	A6T015	468	LEUC_JANMA 3-isopropylmalate dehydratase larg...	472	0	640	64	78
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
16	A5G0G6	466	LEUC_ACICJ 3-isopropylmalate dehydratase larg...	469	0	639	65	78
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
17	Q13DU7	470	LEUC_RHOPS 3-isopropylmalate dehydratase larg...	471	0	633	65	79
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
18	Q3SNV3	468	LEUC_NITWN 3-isopropylmalate dehydratase larg...	471	0	633	65	79
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
19	C3M9V0	469	LEUC_RHISN 3-isopropylmalate dehydratase larg...	472	0	632	65	80
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
20	Q07UU3	470	LEUC_RHOP5 3-isopropylmalate dehydratase larg...	471	0	632	65	79
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
21	Q2RV55	472	LEUC_RHORT 3-isopropylmalate dehydratase larg...	471	0	630	62	78
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
22	Q5FUG3	475	LEUC_GLUOX 3-isopropylmalate dehydratase larg...	474	0	630	64	78
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
23	Q92L76	469	LEUC_RHIME 3-isopropylmalate dehydratase larg...	472	0	629	65	79
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
24	Q2J3A1	470	LEUC_RHOP2 3-isopropylmalate dehydratase larg...	471	0	629	65	79
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
25	Q0BAC8	469	LEUC_BURCM 3-isopropylmalate dehydratase larg...	472	0	628	65	78
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
26	B1Z1N0	469	LEUC_BURA4 3-isopropylmalate dehydratase larg...	472	0	628	65	78
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
27	Q6ND69	469	LEUC_RHOPA 3-isopropylmalate dehydratase larg...	475	0	628	64	79
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
28	Q393X2	469	LEUC_BURS3 3-isopropylmalate dehydratase larg...	472	0	628	65	78
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
29	Q606F2	470	LEUC_METCA 3-isopropylmalate dehydratase larg...	469	0	627	65	77
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
30	A0AZ60	469	LEUC_BURCH 3-isopropylmalate dehydratase larg...	472	0	627	64	78
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
31	B1K377	469	LEUC_BURCC 3-isopropylmalate dehydratase larg...	472	0	627	64	78
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.

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