rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | P0CS49 | 473 | PRP46_CRYNB Pre-mRNA-splicing factor PRP46 OS... | 93 | 0.016 | 41.2 | 24 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 32 | Q6NZH4 | 410 | LIS1_XENTR Lissencephaly-1 homolog OS=Xenopus... | 123 | 0.0006 | 45.4 | 27 | 41 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 33 | Q90ZL4 | 410 | LIS1_XENLA Lissencephaly-1 homolog OS=Xenopus... | 123 | 0.0006 | 45.4 | 27 | 41 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 34 | Q5M786 | 334 | WDR5_XENTR WD repeat-containing protein 5 OS=... | 155 | 7.6 | 32.3 | 25 | 43 | GO:0000123; C:histone acetyltransferase complex; ISS:UniProtKB.::GO:0071339; C:MLL1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; ISS:UniProtKB. | | | | | | | | | | GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0034968; P:histone lysine methylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 35 | Q8HXX0 | 410 | LIS1_MACFA Platelet-activating factor acetylh... | 100 | 0.0008 | 45.1 | 26 | 50 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 36 | P0CS42 | 433 | LIS1_CRYNJ Nuclear distribution protein PAC1 ... | 73 | 0.12 | 38.1 | 30 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 37 | P0CS43 | 433 | LIS1_CRYNB Nuclear distribution protein PAC1 ... | 73 | 0.12 | 38.1 | 30 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 38 | Q9GL51 | 410 | LIS1_PIG Platelet-activating factor acetylhyd... | 100 | 0.0008 | 45.1 | 26 | 50 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 39 | Q2KIG2 | 334 | WDR5_BOVIN WD repeat-containing protein 5 OS=... | 208 | 0.0000005 | 55.1 | 22 | 44 | GO:0000123; C:histone acetyltransferase complex; ISS:UniProtKB.::GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; ISS:UniProtKB. | | | | | | | | | | GO:0051568; P:histone H3-K4 methylation; ISS:UniProtKB.::GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 40 | Q4RJN5 | 410 | LIS1_TETNG Lissencephaly-1 homolog OS=nigrovi... | 151 | 0.00001 | 50.8 | 25 | 46 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 41 | Q498M4 | 334 | WDR5_RAT WD repeat-containing protein 5 OS=Ra... | 208 | 0.0000005 | 55.1 | 22 | 44 | GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; ISS:UniProtKB. | | | | | | | | | | GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 42 | P61965 | 334 | WDR5_MOUSE WD repeat-containing protein 5 OS=... | 208 | 0.0000005 | 55.1 | 22 | 44 | GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; ISS:UniProtKB. | | | | | | | | | | GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0001501; P:skeletal system development; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 43 | P61964 | 334 | WDR5_HUMAN WD repeat-containing protein 5 OS=... | 208 | 0.0000005 | 55.1 | 22 | 44 | GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:BHF-UCL.::GO:0071339; C:MLL1 complex; IDA:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.::GO:0051568; P:histone H3-K4 methylation; IDA:UniProtKB.::GO:0043984; P:histone H4-K16 acetylation; IDA:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 44 | Q7T394 | 410 | LIS1A_DANRE Lissencephaly-1 homolog A OS=Dani... | 59 | 0.007 | 42 | 34 | 58 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0048854; P:brain morphogenesis; IMP:ZFIN.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 45 | A4RDD7 | 341 | EIF3I_MAGO7 Eukaryotic translation initiation... | 243 | 0.0000000003 | 64.7 | 24 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0043581; P:mycelium development; IEP:PAMGO_MGG. | 46 | B5X3Z6 | 410 | LIS1A_SALSA Lissencephaly-1 homolog A OS=Salm... | 74 | 0.003 | 43.1 | 31 | 51 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 47 | A7S338 | 409 | LIS1_NEMVE Lissencephaly-1 homolog OS=Nematos... | 64 | 0.001 | 44.7 | 36 | 55 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 48 | Q75AV4 | 449 | PFS2_ASHGO Polyadenylation factor subunit 2 O... | 83 | 7.7 | 32.3 | 27 | 43 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW. | 49 | Q2GTM8 | 341 | EIF3I_CHAGB Eukaryotic translation initiation... | 240 | 0.000000001 | 63.2 | 25 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 50 | Q17963 | 376 | TG125_CAEEL WD repeat-containing protein tag-... | 145 | 0.00008 | 48.1 | 22 | 44 | GO:0005634; C:nucleus; IDA:WormBase. | | | | | | | | | | | | | | | | | | | | GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0051568; P:histone H3-K4 methylation; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase. | 51 | Q7SZM9 | 519 | TB1RA_XENLA F-box-like/WD repeat-containing p... | 85 | 0.037 | 40 | 29 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 52 | Q95RJ9 | 700 | EBI_DROME F-box-like/WD repeat-containing pro... | 107 | 0.32 | 37 | 27 | 41 | GO:0005700; C:polytene chromosome; IDA:FlyBase.::GO:0017053; C:transcriptional repressor complex; IGI:FlyBase. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:FlyBase.::GO:0070491; F:repressing transcription factor binding; IPI:FlyBase. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0022416; P:chaeta development; IMP:FlyBase.::GO:0042676; P:compound eye cone cell fate commitment; TAS:FlyBase.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IPI:GOC.::GO:0007219; P:Notch signaling pathway; TAS:FlyBase.::GO:0042461; P:photoreceptor cell development; IMP:FlyBase.::GO:0031065; P:positive regulation of histone deacetylation; IDA:FlyBase.::GO:0045572; P:positive regulation of imaginal disc growth; IMP:FlyBase.::GO:0045747; P:positive regulation of Notch signaling pathway; IDA:FlyBase.::GO:0042058; P:regulation of epidermal growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0030162; P:regulation of proteolysis; TAS:FlyBase.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.::GO:0035220; P:wing disc development; IMP:FlyBase. | 53 | P42841 | 465 | PFS2_YEAST Polyadenylation factor subunit 2 O... | 73 | 5 | 33.1 | 26 | 44 | GO:0005847; C:mRNA cleavage and polyadenylation specificity factor complex; IDA:SGD. | | | | | | | | | | | | | | | | | | | | GO:0006379; P:mRNA cleavage; IDA:SGD.::GO:0006378; P:mRNA polyadenylation; IDA:SGD. | 54 | Q6GPC6 | 522 | TB1RB_XENLA F-box-like/WD repeat-containing p... | 85 | 0.039 | 39.7 | 29 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 55 | Q4P9P9 | 453 | LIS1_USTMA Nuclear distribution protein PAC1 ... | 92 | 1 | 35.4 | 32 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 56 | Q9BZK7 | 514 | TBL1R_HUMAN F-box-like/WD repeat-containing p... | 85 | 0.036 | 40 | 29 | 47 | GO:0005876; C:spindle microtubule; IDA:UniProtKB.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 57 | Q8BHJ5 | 514 | TBL1R_MOUSE F-box-like/WD repeat-containing p... | 85 | 0.037 | 40 | 29 | 47 | | | | | | | | | | | GO:0003714; F:transcription corepressor activity; IMP:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 58 | Q9BQ87 | 522 | TBL1Y_HUMAN F-box-like/WD repeat-containing p... | 85 | 0.53 | 36.2 | 28 | 46 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 59 | B7PS00 | 411 | LIS1_IXOSC Lissencephaly-1 homolog OS=Ixodes ... | 60 | 0.0003 | 46.6 | 40 | 58 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 60 | Q8VBV4 | 629 | FBXW7_MOUSE F-box/WD repeat-containing protei... | 76 | 0.058 | 39.3 | 32 | 53 | GO:0005783; C:endoplasmic reticulum; IDA:MGI.::GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI. | | | | | | | | | | GO:0007219; P:Notch signaling pathway; IDA:MGI.::GO:0016567; P:protein ubiquitination; ISS:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB. | 61 | Q9D7H2 | 328 | WDR5B_MOUSE WD repeat-containing protein 5B O... | 218 | 0.0000001 | 56.6 | 22 | 42 | | | | | | | | | | | | | | | | | | | | | |