Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL004C
Length:
417
Number of sequences:
5887
Description:
YGL004C RPN14 SGDID:S000002972, Chr VII from 491956-490703, Genome Release 64-1-1, reverse complement, Verified ORF, "Proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasome regulatory particle (RP); null mutants accumulate ubiquitinated Gcn4p and display decreased 26S proteasome stability; interacts with Rpt5p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P53196    417   RPN14_YEAST 26S proteasome regulatory subunit...4170     863     100     100GO:0005829; C:cytosol; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0070682; P:proteasome regulatory particle assembly; IMP:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:SGD.
2Q5ZK69    392   PAAF1_CHICK Proteasomal ATPase-associated fac...2273e-26     112     32     50GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
3Q9BRP4    392   PAAF1_HUMAN Proteasomal ATPase-associated fac...2461e-25     110     30     48GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.
4Q148I1    392   PAAF1_BOVIN Proteasomal ATPase-associated fac...2457e-23     102     29     47GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
5Q8MYE8    425   PAAF1_DICDI Probable proteasomal ATPase-assoc...2678e-23     102     29     50GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
6A0DB19    403   LIS11_PARTE Lissencephaly-1 homolog 1 OS=Para...1083.8     33.5     26     41GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
7A0CH87    403   LIS12_PARTE Lissencephaly-1 homolog 2 OS=Para...870.004     42.7     24     49GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
8Q00808    1356   HETE1_PODAS Vegetative incompatibility protei...2570.000000006     62     25     43
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
9O43071    558   PRP17_SCHPO Pre-mRNA-processing factor 17 OS=...2190.000000000004     71.6     28     42GO:0005681; C:spliceosomal complex; ISS:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; ISS:PomBase.
10B5X3C4    410   LIS1B_SALSA Lissencephaly-1 homolog B OS=Salm...600.001     44.7     35     58GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
11Q6CP71    452   PFS2_KLULA Polyadenylation factor subunit 2 O...682.6     33.9     24     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
12Q9V3J8    361   WDS_DROME Protein will die slowly OS=Drosophi...1582.3     33.9     26     44GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IPI:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0048188; C:Set1C/COMPASS complex; IDA:FlyBase.
GO:0051568; P:histone H3-K4 methylation; IMP:FlyBase.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IGI:FlyBase.
13Q5RE95    330   WDR5B_PONAB WD repeat-containing protein 5B O...2180.0000004     55.5     22     42
14Q54KL5    335   WDR5_DICDI WD repeat-containing protein 5 hom...2170.0000003     55.5     23     41GO:0035097; C:histone methyltransferase complex; ISS:dictyBase.
GO:0042393; F:histone binding; ISS:dictyBase.
GO:0051568; P:histone H3-K4 methylation; ISS:dictyBase.
15C4Q0P6    417   LIS1_SCHMA Lissencephaly-1 homolog OS=Schisto...449.3     32.3     36     55GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
16O13615    473   PRP46_SCHPO Pre-mRNA-splicing factor prp5 OS=...930.02     40.8     26     44GO:0005681; C:spliceosomal complex; IDA:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; IMP:PomBase.
17Q5REG7    410   LIS1_PONAB Platelet-activating factor acetylh...1000.0008     45.1     26     50GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
18Q9QXE7    527   TBL1X_MOUSE F-box-like/WD repeat-containing p...850.11     38.5     28     47GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003714; F:transcription corepressor activity; IMP:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
GO:0045444; P:fat cell differentiation; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:MGI.::GO:0043627; P:response to estrogen stimulus; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
19Q86VZ2    330   WDR5B_HUMAN WD repeat-containing protein 5B O...2180.0000004     55.1     22     42
20A8X8C6    368   TG125_CAEBR WD repeat-containing protein tag-...1740.000001     53.9     24     43
21Q5IS43    410   LIS1_PANTR Platelet-activating factor acetylh...1000.005     42.4     25     49GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
22P43034    410   LIS1_HUMAN Platelet-activating factor acetylh...1000.0008     45.1     26     50GO:0000235; C:astral microtubule; IDA:UniProtKB.::GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; ISS:BHF-UCL.::GO:0000776; C:kinetochore; IDA:UniProtKB.::GO:0031512; C:motile primary cilium; ISS:BHF-UCL.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:BHF-UCL.
GO:0034452; F:dynactin binding; ISS:BHF-UCL.::GO:0008201; F:heparin binding; ISS:BHF-UCL.::GO:0008017; F:microtubule binding; ISS:BHF-UCL.::GO:0043274; F:phospholipase binding; ISS:BHF-UCL.::GO:0051219; F:phosphoprotein binding; ISS:BHF-UCL.::GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.
GO:0001675; P:acrosome assembly; ISS:BHF-UCL.::GO:0030036; P:actin cytoskeleton organization; ISS:BHF-UCL.::GO:0008344; P:adult locomotory behavior; IMP:BHF-UCL.::GO:0048854; P:brain morphogenesis; IMP:BHF-UCL.::GO:0021540; P:corpus callosum morphogenesis; IMP:BHF-UCL.::GO:0000132; P:establishment of mitotic spindle orientation; IMP:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0021766; P:hippocampus development; ISS:BHF-UCL.::GO:0021819; P:layer formation in cerebral cortex; ISS:BHF-UCL.::GO:0007611; P:learning or memory; ISS:BHF-UCL.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0031023; P:microtubule organizing center organization; IMP:UniProtKB.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0007405; P:neuroblast proliferation; ISS:BHF-UCL.::GO:0050885; P:neuromuscular process controlling balance; IMP:BHF-UCL.::GO:0001764; P:neuron migration; IMP:UniProtKB.::GO:0046469; P:platelet activating factor metabolic process; ISS:BHF-UCL.::GO:0032319; P:regulation of Rho GTPase activity; ISS:BHF-UCL.::GO:0008090; P:retrograde axon cargo transport; ISS:BHF-UCL.::GO:0007268; P:synaptic transmission; ISS:BHF-UCL.::GO:0047496; P:vesicle transport along microtubule; ISS:BHF-UCL.
23Q803D2    410   LIS1B_DANRE Lissencephaly-1 homolog B OS=Dani...740.002     43.5     31     51GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0045176; P:apical protein localization; IMP:ZFIN.::GO:0048854; P:brain morphogenesis; IMP:ZFIN.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0040023; P:establishment of nucleus localization; IMP:ZFIN.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045494; P:photoreceptor cell maintenance; IMP:ZFIN.::GO:0006810; P:transport; IEA:UniProtKB-KW.
24P63004    410   LIS1_RAT Platelet-activating factor acetylhyd...1000.0008     45.1     26     50GO:0033267; C:axon part; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0030426; C:growth cone; IDA:RGD.::GO:0005871; C:kinesin complex; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0042598; C:vesicular fraction; IDA:RGD.
GO:0045505; F:dynein intermediate chain binding; IDA:RGD.::GO:0047179; F:platelet-activating factor acetyltransferase activity; TAS:RGD.
GO:0021895; P:cerebral cortex neuron differentiation; IMP:RGD.::GO:0051660; P:establishment of centrosome localization; IMP:RGD.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010977; P:negative regulation of neuron projection development; IMP:RGD.::GO:0001764; P:neuron migration; IMP:RGD.::GO:0007097; P:nuclear migration; IMP:RGD.::GO:0045773; P:positive regulation of axon extension; IMP:RGD.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:RGD.::GO:0017145; P:stem cell division; IMP:RGD.
25P63005    410   LIS1_MOUSE Platelet-activating factor acetylh...1000.0008     45.1     26     50GO:0005813; C:centrosome; IDA:MGI.::GO:0031512; C:motile primary cilium; IDA:MGI.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:MGI.
GO:0008017; F:microtubule binding; IDA:MGI.::GO:0051219; F:phosphoprotein binding; IPI:MGI.::GO:0042803; F:protein homodimerization activity; IPI:MGI.
GO:0001675; P:acrosome assembly; IMP:MGI.::GO:0030036; P:actin cytoskeleton organization; IMP:MGI.::GO:0008344; P:adult locomotory behavior; IMP:MGI.::GO:0021766; P:hippocampus development; IMP:MGI.::GO:0021819; P:layer formation in cerebral cortex; IGI:MGI.::GO:0007611; P:learning or memory; IMP:MGI.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007405; P:neuroblast proliferation; IMP:MGI.::GO:0050885; P:neuromuscular process controlling balance; IMP:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0051081; P:nuclear envelope disassembly; IMP:MGI.::GO:0032319; P:regulation of Rho GTPase activity; IMP:MGI.::GO:0008090; P:retrograde axon cargo transport; IDA:MGI.::GO:0007268; P:synaptic transmission; IMP:MGI.
26B0LSW3    410   LIS1_FELCA Platelet-activating factor acetylh...1000.0008     45.1     26     50GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
27P43033    410   LIS1_BOVIN Platelet-activating factor acetylh...1000.0008     45.1     26     50GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0034452; F:dynactin binding; IDA:BHF-UCL.::GO:0045502; F:dynein binding; IDA:BHF-UCL.::GO:0008201; F:heparin binding; IDA:BHF-UCL.::GO:0008017; F:microtubule binding; IDA:MGI.::GO:0043274; F:phospholipase binding; IDA:BHF-UCL.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0046469; P:platelet activating factor metabolic process; IDA:BHF-UCL.::GO:0006810; P:transport; IEA:UniProtKB-KW.
28Q4V8C4    328   WDR5B_RAT WD repeat-containing protein 5B OS=...1750.00007     48.1     22     42
29P0CS48    473   PRP46_CRYNJ Pre-mRNA-splicing factor PRP46 OS...930.017     40.8     24     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
30Q9PTR5    410   LIS1_CHICK Lissencephaly-1 homolog OS=Gallus ...1000.001     44.7     26     50
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
31P0CS49    473   PRP46_CRYNB Pre-mRNA-splicing factor PRP46 OS...930.016     41.2     24     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
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