Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL003C
Length:
566
Number of sequences:
5887
Description:
YGL003C CDH1 SGDID:S000002971, Chr VII from 494174-492474, Genome Release 64-1-1, reverse complement, Verified ORF, "Cell-cycle regulated activator of the anaphase-promoting complex/cyclosome (APC/C), which directs ubiquitination of cyclins resulting in mitotic exit; targets the APC/C to specific substrates including Cdc20p, Ase1p, Cin8p and Fin1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P53197    566   CDH1_YEAST APC/C activator protein CDH1 OS=Sa...5660     1172     100     100GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0010997; F:anaphase-promoting complex binding; IDA:SGD.::GO:0030332; F:cyclin binding; IDA:SGD.::GO:0097027; F:ubiquitin-protein ligase activator activity; IDA:SGD.
GO:0007092; P:activation of mitotic anaphase-promoting complex activity; IMP:SGD.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010697; P:negative regulation of spindle pole body separation; IMP:SGD.::GO:2000600; P:positive regulation of cyclin catabolic process; IDA:SGD.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:SGD.::GO:0008361; P:regulation of cell size; IMP:SGD.
2O13286    556   SRW1_SCHPO WD repeat-containing protein srw1 ...5325e-120     372     41     58GO:0005634; C:nucleus; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0007092; P:activation of mitotic anaphase-promoting complex activity; TAS:PomBase.::GO:0030996; P:cell cycle arrest in response to nitrogen starvation; IMP:PomBase.::GO:0008054; P:cyclin catabolic process; IMP:PomBase.::GO:0045736; P:negative regulation of cyclin-dependent protein kinase activity; IC:PomBase.::GO:0031137; P:regulation of conjugation with cellular fusion; IMP:PomBase.
3O94423    421   MFR1_SCHPO Meiotic fizzy-related protein 1 OS...3283e-110     342     50     70GO:0005634; C:nucleus; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.
GO:0051487; P:activation of anaphase-promoting complex activity involved in meiotic cell cycle; IGI:PomBase.::GO:0030437; P:ascospore formation; IMP:PomBase.::GO:0007138; P:meiotic anaphase II; IMP:PomBase.
4Q9R1K5    493   FZR_MOUSE Fizzy-related protein homolog OS=Mu...5329e-110     343     39     55
GO:0005515; F:protein binding; IPI:IntAct.
GO:0051488; P:activation of anaphase-promoting complex activity; ISS:UniProtKB.::GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0070306; P:lens fiber cell differentiation; IMP:MGI.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0090344; P:negative regulation of cell aging; IMP:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:0045732; P:positive regulation of protein catabolic process; ISS:UniProtKB.::GO:0040020; P:regulation of meiosis; IDA:MGI.
5Q9UM11    496   FZR_HUMAN Fizzy-related protein homolog OS=Ho...5219e-110     343     39     56GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0051488; P:activation of anaphase-promoting complex activity; IDA:UniProtKB.::GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; IDA:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0045732; P:positive regulation of protein catabolic process; IGI:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0070979; P:protein K11-linked ubiquitination; TAS:UniProtKB.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.
6Q8L3Z8    483   FZR2_ARATH Protein FIZZY-RELATED 2 OS=Arabido...3347e-108     338     48     67
GO:0005515; F:protein binding; IPI:TAIR.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016049; P:cell growth; IMP:TAIR.::GO:0042023; P:DNA endoreduplication; IMP:TAIR.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010091; P:trichome branching; IMP:TAIR.
7Q8VZS9    475   FZR1_ARATH Protein FIZZY-RELATED 1 OS=Arabido...3153e-105     331     50     71GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0032877; P:positive regulation of DNA endoreduplication; IMP:TAIR.
8Q8LPL5    481   FZR3_ARATH Protein FIZZY-RELATED 3 OS=Arabido...3045e-100     318     48     68
GO:0005515; F:protein binding; IPI:IntAct.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
9Q54KM3    754   CDH1_DICDI Anaphase-promoting complex subunit...750.057     40     36     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
10Q54MZ3    499   CDC20_DICDI Anaphase-promoting complex subuni...3125e-94     303     45     68GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
11Q9JJ66    499   CDC20_MOUSE Cell division cycle protein 20 ho...3426e-94     303     44     66GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051488; P:activation of anaphase-promoting complex activity; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0090129; P:positive regulation of synapse maturation; IDA:UniProtKB.::GO:0031915; P:positive regulation of synaptic plasticity; IDA:UniProtKB.::GO:0040020; P:regulation of meiosis; IGI:MGI.
12Q62623    499   CDC20_RAT Cell division cycle protein 20 homo...3422e-93     301     44     65GO:0005813; C:centrosome; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051488; P:activation of anaphase-promoting complex activity; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0008284; P:positive regulation of cell proliferation; IMP:RGD.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0031915; P:positive regulation of synaptic plasticity; ISS:UniProtKB.::GO:0050773; P:regulation of dendrite development; IMP:RGD.
13Q12834    499   CDC20_HUMAN Cell division cycle protein 20 ho...3423e-93     301     44     65GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
GO:0051488; P:activation of anaphase-promoting complex activity; IDA:UniProtKB.::GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:Reactome.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0031915; P:positive regulation of synaptic plasticity; ISS:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
14Q5H7C0    499   CDC20_PIG Cell division cycle protein 20 homo...3429e-92     297     43     64GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051488; P:activation of anaphase-promoting complex activity; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0031915; P:positive regulation of synaptic plasticity; ISS:UniProtKB.
15P78972    488   SLP1_SCHPO WD repeat-containing protein slp1 ...3282e-84     277     42     64GO:0032153; C:cell division site; IDA:PomBase.::GO:0000778; C:condensed nuclear chromosome kinetochore; IDA:PomBase.::GO:0033597; C:mitotic checkpoint complex; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007092; P:activation of mitotic anaphase-promoting complex activity; TAS:PomBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0033314; P:mitotic cell cycle DNA replication checkpoint; IGI:PomBase.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IGI:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; IGI:PomBase.
16P26309    610   CDC20_YEAST APC/C activator protein CDC20 OS=...3162e-59     213     36     57GO:0005680; C:anaphase-promoting complex; IPI:SGD.::GO:0033597; C:mitotic checkpoint complex; IDA:SGD.
GO:0010997; F:anaphase-promoting complex binding; IDA:SGD.::GO:0097027; F:ubiquitin-protein ligase activator activity; IDA:SGD.
GO:0051487; P:activation of anaphase-promoting complex activity involved in meiotic cell cycle; IMP:SGD.::GO:0007092; P:activation of mitotic anaphase-promoting complex activity; IMP:SGD.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008054; P:cyclin catabolic process; IMP:SGD.::GO:0007133; P:meiotic anaphase I; IMP:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0031577; P:spindle checkpoint; IPI:SGD.
17Q86Y33    519   CD20B_HUMAN Cell division cycle protein 20 ho...2934e-56     202     37     58
18O94411    509   MFR2_SCHPO Meiotic fizzy-related protein 2 OS...3401e-37     149     29     51GO:0005634; C:nucleus; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.
19Q09786    535   YA98_SCHPO Uncharacterized WD repeat-containi...2542e-32     134     31     53GO:0043234; C:protein complex; NAS:PomBase.
20P50082    593   AMA1_YEAST Meiosis-specific APC/C activator p...3611e-31     132     27     47GO:0005680; C:anaphase-promoting complex; IPI:SGD.
GO:0008047; F:enzyme activator activity; IMP:SGD.
GO:0030476; P:ascospore wall assembly; IMP:SGD.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007127; P:meiosis I; IMP:SGD.::GO:0045732; P:positive regulation of protein catabolic process; IMP:SGD.
21Q09373    507   FZY1_CAEEL WD repeat-containing protein fzy-1...4232e-28     122     25     45GO:0000793; C:condensed chromosome; IDA:WormBase.::GO:0005737; C:cytoplasm; IDA:WormBase.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0007091; P:mitotic metaphase/anaphase transition; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.
22Q8YRI1    1526   YY46_NOSS1 Uncharacterized WD repeat-containi...1500.000000004     63.5     27     57
23Q8YTC2    1258   Y2800_NOSS1 Uncharacterized WD repeat-contain...1250.011     42.4     26     43
GO:0043531; F:ADP binding; IEA:InterPro.
GO:0006952; P:defense response; IEA:InterPro.
24Q00808    1356   HETE1_PODAS Vegetative incompatibility protei...1130.013     42.4     26     48
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
25Q8R537    318   PEX7_CRIGR Peroxisomal targeting signal 2 rec...1180.009     42     28     47GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
GO:0005053; F:peroxisome matrix targeting signal-2 binding; ISS:UniProtKB.
GO:0008611; P:ether lipid biosynthetic process; ISS:UniProtKB.::GO:0016558; P:protein import into peroxisome matrix; ISS:UniProtKB.
26P97865    318   PEX7_MOUSE Peroxisomal targeting signal 2 rec...1180.009     42     28     47GO:0005829; C:cytosol; IDA:MGI.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
GO:0001958; P:endochondral ossification; IMP:MGI.::GO:0006635; P:fatty acid beta-oxidation; IMP:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0016558; P:protein import into peroxisome matrix; IMP:MGI.
27Q5JTN6    314   WDR38_HUMAN WD repeat-containing protein 38 O...1472.9     34.3     24     44
28P49695    742   PKWA_THECU Probable serine/threonine-protein ...1250.00006     49.7     27     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
29O00628    323   PEX7_HUMAN Peroxisomal targeting signal 2 rec...1180.091     38.9     27     47GO:0005777; C:peroxisome; IDA:UniProtKB.
GO:0005053; F:peroxisome matrix targeting signal-2 binding; IDA:UniProtKB.
GO:0008611; P:ether lipid biosynthetic process; IMP:UniProtKB.::GO:0016558; P:protein import into peroxisome matrix; IMP:UniProtKB.
30Q6NVM2    655   KTNB1_XENTR Katanin p80 WD40-containing subun...860.18     38.5     29     51GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
31Q7ZUV2    694   KTNB1_DANRE Katanin p80 WD40-containing subun...1850.0001     48.5     24     44GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
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