Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL001C
Length:
349
Number of sequences:
5887
Description:
YGL001C ERG26 SGDID:S000002969, Chr VII from 496502-495453, Genome Release 64-1-1, reverse complement, Verified ORF, "C-3 sterol dehydrogenase, catalyzes the second of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q61767    373   3BHS4_MOUSE 3 beta-hydroxysteroid dehydrogena...3648e-24     103     28     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0035634; P:response to stilbenoid; IEP:UniProtKB.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
32Q5IFP1    373   3BHS_CANFA 3 beta-hydroxysteroid dehydrogenas...3681e-23     103     29     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004769; F:steroid delta-isomerase activity; IEA:EC.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
33Q9H2F3    369   3BHS7_HUMAN 3 beta-hydroxysteroid dehydrogena...3591e-23     103     27     45GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; NAS:UniProtKB.::GO:0047016; F:cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006699; P:bile acid biosynthetic process; TAS:UniProtKB.
34P21097    346   3BHS_VACCC 3 beta-hydroxysteroid dehydrogenas...3632e-23     102     25     45
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004769; F:steroid delta-isomerase activity; IEA:EC.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
35P22071    373   3BHS1_RAT 3 beta-hydroxysteroid dehydrogenase...3642e-23     102     27     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0030061; C:mitochondrial crista; IDA:RGD.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IDA:RGD.::GO:0035410; F:dihydrotestosterone 17-beta-dehydrogenase activity; IDA:RGD.::GO:0051287; F:NAD binding; IDA:RGD.::GO:0005496; F:steroid binding; IPI:RGD.::GO:0004769; F:steroid delta-isomerase activity; IDA:RGD.
GO:0030325; P:adrenal gland development; IEP:RGD.::GO:0018879; P:biphenyl metabolic process; IEP:RGD.::GO:0071236; P:cellular response to antibiotic; IEP:RGD.::GO:0071320; P:cellular response to cAMP; IEP:RGD.::GO:0071549; P:cellular response to dexamethasone stimulus; IEP:RGD.::GO:0044344; P:cellular response to fibroblast growth factor stimulus; IEP:RGD.::GO:0071372; P:cellular response to follicle-stimulating hormone stimulus; IEP:RGD.::GO:0071333; P:cellular response to glucose stimulus; IEP:RGD.::GO:0070301; P:cellular response to hydrogen peroxide; IEP:RGD.::GO:0032869; P:cellular response to insulin stimulus; IEP:RGD.::GO:0071373; P:cellular response to luteinizing hormone stimulus; IEP:RGD.::GO:0071288; P:cellular response to mercury ion; IEP:RGD.::GO:0071406; P:cellular response to methylmercury; IEP:RGD.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEP:RGD.::GO:0018894; P:dibenzo-p-dioxin metabolic process; IEP:RGD.::GO:0016101; P:diterpenoid metabolic process; IEP:RGD.::GO:0006703; P:estrogen biosynthetic process; IEP:RGD.::GO:0008585; P:female gonad development; IEP:RGD.::GO:0050756; P:fractalkine metabolic process; IEP:RGD.::GO:0030851; P:granulocyte differentiation; IEP:RGD.::GO:0021766; P:hippocampus development; IEP:RGD.::GO:0017143; P:insecticide metabolic process; IEP:RGD.::GO:0033327; P:Leydig cell differentiation; IEP:RGD.::GO:0060135; P:maternal process involved in female pregnancy; IEP:RGD.::GO:0006082; P:organic acid metabolic process; IEP:RGD.::GO:0030728; P:ovulation; IEP:RGD.::GO:0018958; P:phenol-containing compound metabolic process; IEP:RGD.::GO:0046470; P:phosphatidylcholine metabolic process; IEP:RGD.::GO:0006701; P:progesterone biosynthetic process; IDA:RGD.::GO:0014823; P:response to activity; IEP:RGD.::GO:0043279; P:response to alkaloid; IEP:RGD.::GO:0046685; P:response to arsenic-containing substance; IEP:RGD.::GO:0046686; P:response to cadmium ion; IEP:RGD.::GO:0051592; P:response to calcium ion; IEP:RGD.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0070542; P:response to fatty acid; IEP:RGD.::GO:0060992; P:response to fungicide; IEP:RGD.::GO:0009635; P:response to herbicide; IEP:RGD.::GO:0033591; P:response to L-ascorbic acid; IEP:RGD.::GO:0010288; P:response to lead ion; IEP:RGD.::GO:0010226; P:response to lithium ion; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0033197; P:response to vitamin E; IEP:RGD.::GO:0061370; P:testosterone biosynthetic process; IEP:RGD.::GO:0018970; P:toluene metabolic process; IEP:RGD.
36P26670    346   3BHS_VACCW 3 beta-hydroxysteroid dehydrogenas...3633e-23     102     25     45
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004769; F:steroid delta-isomerase activity; IEA:EC.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
37P14893    373   3BHS_BOVIN 3 beta-hydroxysteroid dehydrogenas...3664e-23     102     28     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0030868; C:smooth endoplasmic reticulum membrane; IDA:UniProtKB.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004769; F:steroid delta-isomerase activity; IEA:EC.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
38Q60555    373   3BHS1_MESAU 3 beta-hydroxysteroid dehydrogena...3657e-23     101     28     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004769; F:steroid delta-isomerase activity; IEA:EC.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
39Q9N119    373   3BHS_PIG 3 beta-hydroxysteroid dehydrogenase/...3681e-22     100     28     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004769; F:steroid delta-isomerase activity; IEA:EC.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
40P24815    373   3BHS1_MOUSE 3 beta-hydroxysteroid dehydrogena...3705e-22     98.6     28     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004769; F:steroid delta-isomerase activity; IEA:EC.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
41Q61694    373   3BHS5_MOUSE 3 beta-hydroxysteroid dehydrogena...3646e-22     98.6     27     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IDA:MGI.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0035634; P:response to stilbenoid; IEP:UniProtKB.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
42O35296    373   3BHS3_MESAU 3 beta-hydroxysteroid dehydrogena...3717e-22     98.2     29     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
43P22072    373   3BHS2_RAT 3 beta-hydroxysteroid dehydrogenase...3637e-22     98.2     27     42GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004769; F:steroid delta-isomerase activity; IEA:EC.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
44Q8X7P7    331   GNE_ECO57 UDP-N-acetylglucosamine 4-epimerase...3455e-20     92.4     26     46
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003974; F:UDP-N-acetylglucosamine 4-epimerase activity; IEA:EC.
GO:0044237; P:cellular metabolic process; IEA:InterPro.
45O35048    338   3BHS7_RAT 3 beta-hydroxysteroid dehydrogenase...3552e-19     90.5     26     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.::GO:0047016; F:cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity; IDA:RGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0008206; P:bile acid metabolic process; TAS:RGD.::GO:0001558; P:regulation of cell growth; IDA:RGD.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
46Q54L85    328   NSDHL_DICDI Sterol-4-alpha-carboxylate 3-dehy...3555e-17     84     25     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0047012; F:sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity; IEA:EC.
GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.
47P75821    337   YBJS_ECOLI Uncharacterized protein ybjS OS=Es...2947e-17     83.6     26     45
GO:0003824; F:catalytic activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0044237; P:cellular metabolic process; IEA:InterPro.
48P73212    343   DFRA_SYNY3 Putative dihydroflavonol-4-reducta...3490.00000000000005     75.9     24     42
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0045552; F:dihydrokaempferol 4-reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0009813; P:flavonoid biosynthetic process; IEA:UniProtKB-KW.
49Q6GZS4    355   052L_FRG3G Uncharacterized protein 052L OS=Fr...3620.00000000000005     75.9     25     42
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
50P55584    356   Y4NL_RHISN Uncharacterized protein y4nL OS=Rh...3510.00000000000007     75.1     23     40
GO:0003824; F:catalytic activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0044237; P:cellular metabolic process; IEA:InterPro.
51Q57664    305   GALE_METJA Putative UDP-glucose 4-epimerase O...3540.00000000000008     74.7     25     44
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003978; F:UDP-glucose 4-epimerase activity; IEA:EC.
GO:0006012; P:galactose metabolic process; IEA:UniProtKB-KW.
52O65781    350   GALE2_CYATE UDP-glucose 4-epimerase GEPI48 OS...3100.0000000000004     72.8     24     43
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003978; F:UDP-glucose 4-epimerase activity; IEA:EC.
GO:0006012; P:galactose metabolic process; IEA:UniProtKB-KW.
53Q9T0A7    350   GALE3_ARATH UDP-glucose 4-epimerase 3 OS=Arab...3020.000000000004     70.1     23     43GO:0005829; C:cytosol; IDA:TAIR.
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0046983; F:protein dimerization activity; IPI:TAIR.::GO:0003978; F:UDP-glucose 4-epimerase activity; IDA:TAIR.
GO:0042546; P:cell wall biogenesis; IMP:TAIR.::GO:0006012; P:galactose metabolic process; IEA:UniProtKB-KW.
54P21977    332   GALE_STRTR UDP-glucose 4-epimerase OS=Strepto...2580.00000000007     66.2     24     47
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003978; F:UDP-glucose 4-epimerase activity; IEA:EC.
GO:0006012; P:galactose metabolic process; IEA:UniProtKB-KW.
55Q43070    350   GALE1_PEA UDP-glucose 4-epimerase OS=Pisum sa...3710.0000000001     65.5     23     40
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003978; F:UDP-glucose 4-epimerase activity; IEA:EC.
GO:0006012; P:galactose metabolic process; IEA:UniProtKB-KW.
56Q9SN58    351   GALE2_ARATH UDP-glucose 4-epimerase 2 OS=Arab...3100.0000000002     65.5     23     43
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0046983; F:protein dimerization activity; IPI:TAIR.::GO:0003978; F:UDP-glucose 4-epimerase activity; IDA:TAIR.
GO:0006012; P:galactose metabolic process; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IMP:TAIR.
57Q42605    351   GALE1_ARATH UDP-glucose 4-epimerase 1 OS=Arab...3810.0000000004     63.9     24     39GO:0005829; C:cytosol; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0046983; F:protein dimerization activity; IPI:TAIR.::GO:0003978; F:UDP-glucose 4-epimerase activity; IDA:TAIR.
GO:0006012; P:galactose metabolic process; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IMP:TAIR.
58Q8R059    347   GALE_MOUSE UDP-glucose 4-epimerase OS=Mus mus...3140.0000000005     63.5     22     40
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003978; F:UDP-glucose 4-epimerase activity; IDA:MGI.
59Q7WTB1    330   GALE_LACHE UDP-glucose 4-epimerase OS=Lactoba...2510.0000000008     62.8     25     44
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003978; F:UDP-glucose 4-epimerase activity; IEA:EC.
GO:0006012; P:galactose metabolic process; IEA:UniProtKB-KW.
60P55180    339   GALE_BACSU UDP-glucose 4-epimerase OS=Bacillu...3700.0000000009     62.8     22     41
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003978; F:UDP-glucose 4-epimerase activity; IEA:EC.
GO:0006012; P:galactose metabolic process; IEA:UniProtKB-KW.
61Q89187    210   3BHS_VAR67 3 beta-hydroxysteroid dehydrogenas...1550.000000001     61.2     27     45
GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004769; F:steroid delta-isomerase activity; IEA:EC.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
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