rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P43623 | 340 | METC_YEAST Putative cystathionine beta-lyase ... | 340 | 0 | 697 | 100 | 100 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0047804; F:cysteine-S-conjugate beta-lyase activity; IDA:SGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0019450; P:L-cysteine catabolic process to pyruvate; IMP:SGD.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 2 | Q52811 | 396 | METC_RHIL3 Putative cystathionine beta-lyase ... | 338 | 1e-102 | 314 | 45 | 62 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 3 | P44527 | 396 | METC_HAEIN Cystathionine beta-lyase OS=Haemop... | 341 | 5e-87 | 274 | 40 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 4 | P18949 | 395 | METC_SALTY Cystathionine beta-lyase OS=Salmon... | 335 | 1e-84 | 267 | 41 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 5 | P06721 | 395 | METC_ECOLI Cystathionine beta-lyase metC OS=E... | 337 | 8e-83 | 263 | 40 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; IDA:EcoCyc.::GO:0080146; F:L-cysteine desulfhydrase activity; IMP:EcoCyc.::GO:0030170; F:pyridoxal phosphate binding; IDA:EcoCyc. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 6 | Q07703 | 396 | METC_BORAV Cystathionine beta-lyase OS=Bordet... | 329 | 5e-65 | 217 | 38 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 7 | Q1M0P5 | 380 | METB_HELPX Cystathionine gamma-synthase OS=He... | 330 | 1e-53 | 186 | 36 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 8 | P56069 | 380 | METB_HELPY Cystathionine gamma-synthase OS=py... | 330 | 3e-53 | 185 | 36 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 9 | Q9ZMW7 | 380 | METB_HELPJ Cystathionine gamma-synthase OS=He... | 333 | 9e-53 | 184 | 36 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 10 | P24601 | 319 | METB_HERAU Probable cystathionine gamma-synth... | 308 | 2e-51 | 179 | 34 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 11 | O31632 | 390 | METC_BACSU Cystathionine beta-lyase metC OS=B... | 338 | 1e-50 | 179 | 33 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 12 | O05394 | 379 | MCCB_BACSU Cystathionine gamma-lyase OS=Bacil... | 288 | 6e-47 | 168 | 33 | 57 | | | | | | | | | | | GO:0004123; F:cystathionine gamma-lyase activity; IEA:EC.::GO:0047982; F:homocysteine desulfhydrase activity; IEA:EC.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro. | 13 | P55216 | 392 | CGL2_CAEEL Putative cystathionine gamma-lyase... | 327 | 1e-46 | 168 | 34 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004123; F:cystathionine gamma-lyase activity; IEA:EC.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase. | 14 | P32929 | 405 | CGL_HUMAN Cystathionine gamma-lyase OS=Homo s... | 332 | 5e-46 | 166 | 33 | 53 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004123; F:cystathionine gamma-lyase activity; IDA:UniProtKB.::GO:0047982; F:homocysteine desulfhydrase activity; TAS:Reactome.::GO:0080146; F:L-cysteine desulfhydrase activity; TAS:Reactome.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IMP:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IDA:UniProtKB. | | | | | | | | | | GO:0019344; P:cysteine biosynthetic process; IDA:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:UniProtKB.::GO:0070814; P:hydrogen sulfide biosynthetic process; IDA:UniProtKB.::GO:0051289; P:protein homotetramerization; IPI:UniProtKB.::GO:0044524; P:protein sulfhydration; IMP:UniProtKB.::GO:0018272; P:protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; IDA:UniProtKB.::GO:0000098; P:sulfur amino acid catabolic process; TAS:Reactome.::GO:0019346; P:transsulfuration; TAS:Reactome. | 15 | A2RM21 | 380 | METC_LACLM Cystathionine beta-lyase OS=Lactoc... | 322 | 4e-45 | 164 | 34 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 16 | P0A4K2 | 380 | METC_LACLA Cystathionine beta-lyase OS=lactis... | 322 | 4e-45 | 164 | 34 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 17 | Q60HG7 | 405 | CGL_MACFA Cystathionine gamma-lyase OS=Macaca... | 331 | 5e-44 | 161 | 31 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004123; F:cystathionine gamma-lyase activity; ISS:UniProtKB.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0019344; P:cysteine biosynthetic process; ISS:UniProtKB.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0044524; P:protein sulfhydration; ISS:UniProtKB.::GO:0018272; P:protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; ISS:UniProtKB. | 18 | P0C2T9 | 380 | METC_LACLC Cystathionine beta-lyase OS=Lactoc... | 322 | 3e-43 | 159 | 34 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 19 | Q19QT7 | 405 | CGL_PIG Cystathionine gamma-lyase OS=Sus scro... | 332 | 1e-42 | 157 | 32 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004123; F:cystathionine gamma-lyase activity; ISS:UniProtKB.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0019344; P:cysteine biosynthetic process; ISS:UniProtKB.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0044524; P:protein sulfhydration; ISS:UniProtKB.::GO:0018272; P:protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; ISS:UniProtKB. | 20 | Q58DW2 | 405 | CGL_BOVIN Cystathionine gamma-lyase OS=Bos ta... | 332 | 3e-42 | 156 | 31 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004123; F:cystathionine gamma-lyase activity; ISS:UniProtKB.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0019344; P:cysteine biosynthetic process; ISS:UniProtKB.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0044524; P:protein sulfhydration; ISS:UniProtKB.::GO:0018272; P:protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; ISS:UniProtKB. | 21 | Q8VCN5 | 398 | CGL_MOUSE Cystathionine gamma-lyase OS=Mus mu... | 332 | 9e-42 | 155 | 31 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004123; F:cystathionine gamma-lyase activity; ISS:UniProtKB.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IDA:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IMP:UniProtKB.::GO:0019344; P:cysteine biosynthetic process; ISS:UniProtKB.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0044524; P:protein sulfhydration; IDA:UniProtKB.::GO:0018272; P:protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; ISS:UniProtKB. | 22 | P46807 | 388 | METB_MYCLE Cystathionine gamma-synthase OS=My... | 334 | 3e-41 | 153 | 30 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 23 | P66875 | 388 | METB_MYCTU Cystathionine gamma-synthase OS=My... | 334 | 5e-41 | 152 | 30 | 49 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:MTBBASE. | | | | | | | | | | GO:0004123; F:cystathionine gamma-lyase activity; IDA:MTBBASE.::GO:0003962; F:cystathionine gamma-synthase activity; IDA:MTBBASE.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0019343; P:cysteine biosynthetic process via cystathionine; IMP:MTBBASE.::GO:0019279; P:L-methionine biosynthetic process from L-homoserine via cystathionine; IMP:MTBBASE. | 24 | P66876 | 388 | METB_MYCBO Cystathionine gamma-synthase OS=My... | 334 | 5e-41 | 152 | 30 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 25 | P18757 | 398 | CGL_RAT Cystathionine gamma-lyase OS=Rattus n... | 332 | 1e-40 | 152 | 30 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004121; F:cystathionine beta-lyase activity; IDA:RGD.::GO:0004123; F:cystathionine gamma-lyase activity; ISS:UniProtKB.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0019344; P:cysteine biosynthetic process; ISS:UniProtKB.::GO:0006749; P:glutathione metabolic process; IMP:RGD.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; IMP:RGD.::GO:0008285; P:negative regulation of cell proliferation; IMP:RGD.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0044524; P:protein sulfhydration; ISS:UniProtKB.::GO:0018272; P:protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; ISS:UniProtKB.::GO:0019346; P:transsulfuration; TAS:RGD. | 26 | Q55DV9 | 387 | CGL_DICDI Cystathionine gamma-lyase OS=Dictyo... | 337 | 2e-40 | 151 | 28 | 50 | GO:0005737; C:cytoplasm; ISS:dictyBase.::GO:0005615; C:extracellular space; IDA:dictyBase. | | | | | | | | | | GO:0004123; F:cystathionine gamma-lyase activity; ISS:dictyBase.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW. | 27 | P55217 | 563 | METB_ARATH Cystathionine gamma-synthase, chlo... | 317 | 7e-38 | 146 | 31 | 49 | GO:0009570; C:chloroplast stroma; IDA:TAIR. | | | | | | | | | | GO:0003962; F:cystathionine gamma-synthase activity; IDA:TAIR.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IMP:TAIR.::GO:0001887; P:selenium compound metabolic process; IDA:TAIR. | 28 | O31631 | 373 | METI_BACSU Cystathionine gamma-synthase/O-ace... | 278 | 9e-38 | 144 | 32 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 29 | P13254 | 398 | MEGL_PSEPU Methionine gamma-lyase OS=Pseudomo... | 314 | 2e-37 | 143 | 28 | 48 | | | | | | | | | | | GO:0018826; F:methionine gamma-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro. | 30 | P00935 | 386 | METB_ECOLI Cystathionine gamma-synthase OS=Es... | 322 | 2e-35 | 137 | 29 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003962; F:cystathionine gamma-synthase activity; IDA:EcoCyc.::GO:0042802; F:identical protein binding; IPI:EcoCyc.::GO:0030170; F:pyridoxal phosphate binding; IDA:EcoCyc. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IMP:EcoCyc. | 31 | Q83A83 | 387 | METC_COXBU Cystathionine beta-lyase OS=Coxiel... | 335 | 1e-33 | 132 | 27 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. |