Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFR052W
Length:
274
Number of sequences:
5887
Description:
YFR052W RPN12 SGDID:S000001948, Chr VI from 252505-253329, Genome Release 64-1-1, Verified ORF, "Subunit of the 19S regulatory particle of the 26S proteasome lid; synthetically lethal with RPT1, which is an ATPase component of the 19S regulatory particle; physically interacts with Nob1p and Rpn3p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P32496    274   RPN12_YEAST 26S proteasome regulatory subunit...2740     548     100     100GO:0008541; C:proteasome regulatory particle, lid subcomplex; IDA:SGD.::GO:0034515; C:proteasome storage granule; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:SGD.
2P50524    270   RPN12_SCHPO 26S proteasome regulatory subunit...2562e-35     133     34     54GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0008541; C:proteasome regulatory particle, lid subcomplex; ISS:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:PomBase.
3P02889    263   PSMD8_DICDI Probable 26S proteasome non-ATPas...2223e-27     110     32     57GO:0005838; C:proteasome regulatory particle; IEA:InterPro.
GO:0004175; F:endopeptidase activity; ISS:dictyBase.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.
4Q5RE15    289   PSMD8_PONAB 26S proteasome non-ATPase regulat...2523e-26     108     33     54GO:0005838; C:proteasome regulatory particle; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
5P48556    350   PSMD8_HUMAN 26S proteasome non-ATPase regulat...2523e-26     109     33     54GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005838; C:proteasome regulatory particle; TAS:ProtInc.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
6Q9CX56    353   PSMD8_MOUSE 26S proteasome non-ATPase regulat...2594e-26     109     32     54GO:0005838; C:proteasome regulatory particle; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
7Q3SYT7    287   PSMD8_BOVIN 26S proteasome non-ATPase regulat...2533e-25     106     32     53GO:0005838; C:proteasome regulatory particle; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
8Q9SGW3    267   RP12A_ARATH 26S proteasome non-ATPase regulat...2782e-24     103     30     51GO:0009941; C:chloroplast envelope; IDA:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; TAS:TAIR.::GO:0005838; C:proteasome regulatory particle; IEA:InterPro.
GO:0048825; P:cotyledon development; IMP:TAIR.::GO:0009736; P:cytokinin mediated signaling pathway; IEA:UniProtKB-KW.::GO:0009908; P:flower development; IMP:TAIR.::GO:0048366; P:leaf development; IMP:TAIR.::GO:0048528; P:post-embryonic root development; IMP:TAIR.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:TAIR.::GO:0043248; P:proteasome assembly; IMP:TAIR.::GO:0031540; P:regulation of anthocyanin biosynthetic process; IMP:TAIR.::GO:0009733; P:response to auxin stimulus; IMP:TAIR.::GO:0009408; P:response to heat; IMP:TAIR.::GO:0051788; P:response to misfolded protein; IMP:TAIR.::GO:0009647; P:skotomorphogenesis; IMP:TAIR.
9Q23449    250   PSMD8_CAEEL 26S proteasome non-ATPase regulat...2254e-17     81.6     29     49GO:0005838; C:proteasome regulatory particle; IEA:InterPro.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0016246; P:RNA interference; IMP:WormBase.
10Q9FHY0    233   RP12B_ARATH 26S proteasome non-ATPase regulat...1890.000000000004     67.4     25     50GO:0005838; C:proteasome regulatory particle; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
11A3LQ86    467   YTM1_PICST Ribosome biogenesis protein YTM1 O...1132.4     33.1     28     46GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
12Q9US03    817   KLP2_SCHPO Kinesin-like protein 2 OS=Schizosa...732.5     33.5     27     53GO:0000778; C:condensed nuclear chromosome kinetochore; TAS:PomBase.::GO:0005737; C:cytoplasm; IDA:PomBase.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IC:PomBase.::GO:0003777; F:microtubule motor activity; TAS:PomBase.
GO:0031122; P:cytoplasmic microtubule organization; IMP:PomBase.::GO:0030951; P:establishment or maintenance of microtubule cytoskeleton polarity; IMP:PomBase.::GO:0000741; P:karyogamy; IGI:PomBase.::GO:0031534; P:minus-end directed microtubule sliding; IMP:PomBase.::GO:0000022; P:mitotic spindle elongation; IGI:PomBase.
13O28228    191   RLME_ARCFU Ribosomal RNA large subunit methyl...562.9     32.3     29     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0001510; P:RNA methylation; IEA:InterPro.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
14P18299    357   LUXA_KRYAS Alkanal monooxygenase alpha chain ...563.3     32.7     30     54
GO:0047646; F:alkanal monooxygenase (FMN-linked) activity; IEA:EC.
GO:0008218; P:bioluminescence; IEA:UniProtKB-KW.
15A4XGB8    330   BIOB_CALS8 Biotin synthase OS=Caldicellulosir...1344.5     32.3     26     43
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004076; F:biotin synthase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
16B1MZG8    342   HRCA_LEUCK Heat-inducible transcription repre...1085.6     32     26     46
GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
17Q9V2G2    306   MOAA_PYRAB Probable molybdenum cofactor biosy...526.8     31.6     35     58GO:0019008; C:molybdopterin synthase complex; IEA:InterPro.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0003824; F:catalytic activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:HAMAP.
18Q18297    1211   TRPA1_CAEEL Transient receptor potential cati...1208.1     31.6     31     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005216; F:ion channel activity; IEA:UniProtKB-KW.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
19A8PKH2    1096   EIF3A_BRUMA Eukaryotic translation initiation...549.4     31.6     28     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
20Q24498    5127   RY44_DROME Ryanodine receptor 44F OS=Drosophi...609.5     31.6     28     55GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0005219; F:ryanodine-sensitive calcium-release channel activity; TAS:UniProtKB.
GO:0006874; P:cellular calcium ion homeostasis; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006936; P:muscle contraction; IMP:UniProtKB.
21Q21MP3    500   ARAA_SACD2 L-arabinose isomerase OS=Saccharop...769.9     31.2     33     53GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0008733; F:L-arabinose isomerase activity; IEA:EC.::GO:0008736; F:L-fucose isomerase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019568; P:arabinose catabolic process; IEA:UniProtKB-KW.::GO:0006004; P:fucose metabolic process; IEA:InterPro.
records
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