Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFR044C
Length:
481
Number of sequences:
5887
Description:
YFR044C DUG1 SGDID:S000001940, Chr VI from 241437-239992, Genome Release 64-1-1, reverse complement, Verified ORF, "Cys-Gly metallo-di-peptidase; forms a complex with Dug2p and Dug3p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p)"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P43616    481   DUG1_YEAST Cys-Gly metallodipeptidase DUG1 OS...4810     989     100     100GO:0005739; C:mitochondrion; IDA:SGD.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0070573; F:metallodipeptidase activity; IMP:SGD.::GO:0034701; F:tripeptidase activity; IEA:InterPro.
GO:0006751; P:glutathione catabolic process; IMP:SGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
2Q5AKA5    485   DUG1_CANAL Cys-Gly metallodipeptidase DUG1 OS...4740     677     68     80GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016805; F:dipeptidase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0034701; F:tripeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
3Q9P6I2    474   DUG1_SCHPO Cys-Gly metallodipeptidase dug1 OS...4700     535     54     71GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0070573; F:metallodipeptidase activity; ISS:PomBase.::GO:0034701; F:tripeptidase activity; IEA:InterPro.
GO:0006751; P:glutathione catabolic process; ISS:PomBase.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
4Q96KP4    475   CNDP2_HUMAN Cytosolic non-specific dipeptidas...4742e-169     493     52     68GO:0005829; C:cytosol; TAS:Reactome.
GO:0004180; F:carboxypeptidase activity; TAS:Reactome.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0034701; F:tripeptidase activity; IEA:InterPro.
GO:0006750; P:glutathione biosynthetic process; TAS:Reactome.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0000096; P:sulfur amino acid metabolic process; TAS:Reactome.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
5Q9D1A2    475   CNDP2_MOUSE Cytosolic non-specific dipeptidas...4742e-169     493     52     69GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.::GO:0016805; F:dipeptidase activity; IDA:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0034701; F:tripeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IDA:MGI.
6Q5R432    475   CNDP2_PONAB Cytosolic non-specific dipeptidas...4742e-169     493     51     69GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.::GO:0016805; F:dipeptidase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0034701; F:tripeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
7Q6Q0N1    475   CNDP2_RAT Cytosolic non-specific dipeptidase ...4742e-168     490     51     68GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0034701; F:tripeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
8Q3ZC84    475   CNDP2_BOVIN Cytosolic non-specific dipeptidas...4741e-166     486     51     68GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0034701; F:tripeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
9Q66HG3    492   CNDP1_RAT Beta-Ala-His dipeptidase OS=Rattus ...4735e-140     419     45     63
GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.::GO:0016805; F:dipeptidase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0034701; F:tripeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
10Q8BUG2    492   CNDP1_MOUSE Beta-Ala-His dipeptidase OS=Mus m...4758e-139     416     45     62
GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.::GO:0016805; F:dipeptidase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0034701; F:tripeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
11Q96KN2    507   CNDP1_HUMAN Beta-Ala-His dipeptidase OS=Homo ...4706e-138     414     45     63GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.::GO:0016805; F:dipeptidase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0034701; F:tripeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
12P38149    878   DUG2_YEAST Probable di- and tripeptidase DUG2...3887e-52     192     32     50GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0016805; F:dipeptidase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0006751; P:glutathione catabolic process; IMP:SGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
13Q55DP8    408   ACY1_DICDI Aminoacylase-1 OS=Dictyostelium di...940.00006     48.9     35     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004046; F:aminoacylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:InterPro.
GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:InterPro.
14Q6GTS8    502   P20D1_HUMAN Probable carboxypeptidase PM20D1 ...550.0002     47.4     44     60GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
15Q99JW2    408   ACY1_MOUSE Aminoacylase-1 OS=Mus musculus (Mo...1590.44     36.6     26     36GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004046; F:aminoacylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:InterPro.
GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:InterPro.
16P37111    407   ACY1_PIG Aminoacylase-1 OS=Sus scrofa (Pig). ...1020.0004     46.2     29     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004046; F:aminoacylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:InterPro.
GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:InterPro.
17A5IG28    377   DAPE_LEGPC Succinyl-diaminopimelate desucciny...830.0005     45.8     35     47
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0009014; F:succinyl-diaminopimelate desuccinylase activity; IEA:EC.
GO:0019877; P:diaminopimelate biosynthetic process; IEA:UniProtKB-KW.
18Q5ZX46    377   DAPE_LEGPH Succinyl-diaminopimelate desucciny...830.0006     45.8     35     47
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0009014; F:succinyl-diaminopimelate desuccinylase activity; IEA:EC.
GO:0019877; P:diaminopimelate biosynthetic process; IEA:UniProtKB-KW.
19Q5X6L7    377   DAPE_LEGPA Succinyl-diaminopimelate desucciny...830.0006     45.8     35     47
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0009014; F:succinyl-diaminopimelate desuccinylase activity; IEA:EC.
GO:0019877; P:diaminopimelate biosynthetic process; IEA:UniProtKB-KW.
20Q6AYS7    408   ACY1A_RAT Aminoacylase-1A OS=Rattus norvegicu...1030.0006     45.8     28     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004046; F:aminoacylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:InterPro.
GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:InterPro.
21Q5WY21    377   DAPE_LEGPL Succinyl-diaminopimelate desucciny...830.0008     45.4     35     47
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0009014; F:succinyl-diaminopimelate desuccinylase activity; IEA:EC.
GO:0019877; P:diaminopimelate biosynthetic process; IEA:UniProtKB-KW.
22B2FIC0    375   DAPE_STRMK Succinyl-diaminopimelate desucciny...2780.0009     45.1     22     36
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:InterPro.::GO:0009014; F:succinyl-diaminopimelate desuccinylase activity; IEA:EC.
GO:0019877; P:diaminopimelate biosynthetic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.
23P45494    470   PEPV_LACDL Beta-Ala-Xaa dipeptidase OS=Lactob...910.001     45.1     34     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016805; F:dipeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
24Q8CQC2    405   DAPE_STAES Probable succinyl-diaminopimelate ...2870.001     45.1     25     40
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:InterPro.::GO:0009014; F:succinyl-diaminopimelate desuccinylase activity; IEA:EC.
GO:0019877; P:diaminopimelate biosynthetic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.
25Q7WKC6    379   DAPE_BORBR Succinyl-diaminopimelate desucciny...2230.001     44.7     22     39
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0009014; F:succinyl-diaminopimelate desuccinylase activity; IEA:EC.
GO:0019877; P:diaminopimelate biosynthetic process; IEA:UniProtKB-KW.
26Q5HKI1    405   DAPE_STAEQ Probable succinyl-diaminopimelate ...2870.002     44.3     25     40
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:InterPro.::GO:0009014; F:succinyl-diaminopimelate desuccinylase activity; IEA:EC.
GO:0019877; P:diaminopimelate biosynthetic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.
27Q7W8Y3    379   DAPE_BORPA Succinyl-diaminopimelate desucciny...2200.002     43.9     22     39
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0009014; F:succinyl-diaminopimelate desuccinylase activity; IEA:EC.
GO:0019877; P:diaminopimelate biosynthetic process; IEA:UniProtKB-KW.
28Q8C165    503   P20D1_MOUSE Probable carboxypeptidase PM20D1 ...620.002     43.9     34     58GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
29Q03154    408   ACY1_HUMAN Aminoacylase-1 OS=Homo sapiens (Hu...990.002     43.9     27     47GO:0005829; C:cytosol; TAS:ProtInc.
GO:0004046; F:aminoacylase activity; TAS:ProtInc.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:InterPro.
GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:InterPro.
30Q5RFB0    408   ACY1_PONAB Aminoacylase-1 OS=Pongo abelii (Su...990.002     43.9     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004046; F:aminoacylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:InterPro.
GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:InterPro.
31A4XWV4    380   DAPE_PSEMY Succinyl-diaminopimelate desucciny...540.003     43.5     43     56
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:InterPro.::GO:0009014; F:succinyl-diaminopimelate desuccinylase activity; IEA:EC.
GO:0019877; P:diaminopimelate biosynthetic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.
records
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