Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFR038W
Length:
853
Number of sequences:
5887
Description:
YFR038W IRC5 SGDID:S000001934, Chr VI from 229380-231941, Genome Release 64-1-1, Verified ORF, "Putative ATPase containing the DEAD/H helicase-related sequence motif; null mutant displays increased levels of spontaneous Rad52p foci"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151Q92698    747   RAD54_HUMAN DNA repair and recombination prot...1521e-23     110     38     57GO:0005634; C:nucleus; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007126; P:meiosis; TAS:ProtInc.
152P75093    1030   Y020_MYCPN Uncharacterized ATP-dependent heli...1522e-20     100     36     57
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
153P70270    747   RAD54_MOUSE DNA repair and recombination prot...1528e-24     111     38     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0051276; P:chromosome organization; IGI:MGI.::GO:0000724; P:double-strand break repair via homologous recombination; IGI:MGI.::GO:0042493; P:response to drug; IMP:MGI.::GO:0010212; P:response to ionizing radiation; IMP:MGI.
154Q57X81    1077   JBP2_TRYB2 Bifunctional helicase and thymine ...5577e-28     124     25     43GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0050341; F:thymine dioxygenase activity; IMP:UniProtKB.
GO:0070580; P:base J metabolic process; IMP:UniProtKB.
155B3NAN8    784   RAD54_DROER DNA repair and recombination prot...1521e-23     110     36     59GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0043150; P:DNA synthesis involved in double-strand break repair via homologous recombination; ISS:UniProtKB.::GO:0000711; P:meiotic DNA repair synthesis; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
156Q29KH2    782   RAD54_DROPS DNA repair and recombination prot...1522e-23     110     36     59GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0043150; P:DNA synthesis involved in double-strand break repair via homologous recombination; ISS:UniProtKB.::GO:0000711; P:meiotic DNA repair synthesis; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
157B4GS98    782   RAD54_DROPE DNA repair and recombination prot...1525e-23     108     36     59GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0043150; P:DNA synthesis involved in double-strand break repair via homologous recombination; ISS:UniProtKB.::GO:0000711; P:meiotic DNA repair synthesis; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
158P32863    898   RAD54_YEAST DNA repair and recombination prot...1671e-24     114     35     55GO:0005634; C:nucleus; IMP:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0015616; F:DNA translocase activity; IDA:SGD.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0006338; P:chromatin remodeling; IDA:SGD.::GO:0032392; P:DNA geometric change; IDA:SGD.::GO:0045003; P:double-strand break repair via synthesis-dependent strand annealing; TAS:SGD.::GO:0030491; P:heteroduplex formation; IDA:SGD.::GO:0032079; P:positive regulation of endodeoxyribonuclease activity; IDA:SGD.::GO:0000722; P:telomere maintenance via recombination; IMP:SGD.
159Q7YQM3    2492   ATRX_PONPY Transcriptional regulator ATRX OS=...1782e-23     111     35     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
160P46100    2492   ATRX_HUMAN Transcriptional regulator ATRX OS=...1782e-23     111     35     55GO:0005720; C:nuclear heterochromatin; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0070087; F:chromo shadow domain binding; IPI:BHF-UCL.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003678; F:DNA helicase activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006306; P:DNA methylation; TAS:ProtInc.::GO:0006310; P:DNA recombination; TAS:ProtInc.::GO:0006281; P:DNA repair; TAS:ProtInc.::GO:0006355; P:regulation of transcription, DNA-dependent; TAS:ProtInc.
161Q7YQM4    2492   ATRX_PANTR Transcriptional regulator ATRX OS=...1782e-23     111     35     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
162B3LN76    924   RDH54_YEAS1 DNA repair and recombination prot...3432e-24     114     29     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003916; F:DNA topoisomerase activity; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
163P38086    958   RDH54_YEAST DNA repair and recombination prot...3431e-24     114     29     45GO:0005634; C:nucleus; IC:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003916; F:DNA topoisomerase activity; IEA:UniProtKB-KW.::GO:0015616; F:DNA translocase activity; IDA:SGD.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0032392; P:DNA geometric change; IDA:SGD.::GO:0000727; P:double-strand break repair via break-induced replication; TAS:SGD.::GO:0030491; P:heteroduplex formation; IDA:SGD.::GO:0045144; P:meiotic sister chromatid segregation; IMP:SGD.::GO:0007131; P:reciprocal meiotic recombination; IMP:SGD.
164A6ZL17    924   RDH54_YEAS7 DNA repair and recombination prot...3432e-24     114     29     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003916; F:DNA topoisomerase activity; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
165Q09772    811   RDH54_SCHPO Meiotic recombination protein rdh...1588e-18     92.4     33     52GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004003; F:ATP-dependent DNA helicase activity; ISS:PomBase.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0000724; P:double-strand break repair via homologous recombination; IDA:PomBase.::GO:0007131; P:reciprocal meiotic recombination; IDA:PomBase.
166C7GQI8    924   RDH54_YEAS2 DNA repair and recombination prot...3432e-24     114     29     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003916; F:DNA topoisomerase activity; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
167B5VE38    924   RDH54_YEAS6 DNA repair and recombination prot...3433e-24     113     29     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003916; F:DNA topoisomerase activity; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
168Q9GQN5    1311   ATRX_DROME Transcriptional regulator ATRX hom...1574e-20     100     36     53GO:0005722; C:beta-heterochromatin; IDA:FlyBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IDA:FlyBase.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0008347; P:glial cell migration; IMP:FlyBase.::GO:0070868; P:heterochromatin organization involved in chromatin silencing; IMP:FlyBase.::GO:0006917; P:induction of apoptosis; IMP:FlyBase.::GO:0046328; P:regulation of JNK cascade; IGI:FlyBase.
169Q61687    2476   ATRX_MOUSE Transcriptional regulator ATRX OS=...1787e-24     112     36     56GO:0000792; C:heterochromatin; IDA:MGI.::GO:0000228; C:nuclear chromosome; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0030900; P:forebrain development; IMP:MGI.
170P31244    790   RAD16_YEAST DNA repair protein RAD16 OS=Sacch...1637e-19     95.5     35     55GO:0031463; C:Cul3-RING ubiquitin ligase complex; IDA:SGD.::GO:0000113; C:nucleotide-excision repair factor 4 complex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000715; P:nucleotide-excision repair, DNA damage recognition; IDA:SGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:SGD.
171Q9Y4B4    1467   ARIP4_HUMAN Helicase ARIP4 OS=Homo sapiens (H...3364e-20     100     26     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
172P34739    1061   TTF2_DROME Transcription termination factor 2...4050.0000000000003     77.4     24     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; IDA:FlyBase.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0007143; P:female meiosis; IMP:FlyBase.::GO:0034454; P:microtubule anchoring at centrosome; IMP:FlyBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IMP:FlyBase.::GO:0006353; P:transcription termination, DNA-dependent; IDA:FlyBase.
173Q99NG0    1466   ARIP4_MOUSE Helicase ARIP4 OS=Mus musculus (M...3366e-20     99.4     26     40GO:0005634; C:nucleus; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:MGI.::GO:0003712; F:transcription cofactor activity; IDA:MGI.
174Q9UNY4    1162   TTF2_HUMAN Transcription termination factor 2...3060.000000000000001     85.9     26     43GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.::GO:0008023; C:transcription elongation factor complex; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0006369; P:termination of RNA polymerase II transcription; TAS:ProtInc.
175Q9U7E0    1359   ATRX_CAEEL Transcriptional regulator ATRX hom...1780.000000000000001     85.5     31     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0040025; P:vulval development; IMP:WormBase.
176P79051    861   RHP16_SCHPO ATP-dependent helicase rhp16 OS=S...1545e-18     93.2     36     53GO:0000109; C:nucleotide-excision repair complex; IPI:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0034644; P:cellular response to UV; IGI:PomBase.::GO:0006289; P:nucleotide-excision repair; IGI:PomBase.
177Q10332    830   YBMA_SCHPO Uncharacterized ATP-dependent heli...3152e-19     97.8     29     44GO:0005829; C:cytosol; IDA:PomBase.::GO:0000113; C:nucleotide-excision repair factor 4 complex; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; ISS:PomBase.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0006289; P:nucleotide-excision repair; ISS:PomBase.
178Q5NC05    1138   TTF2_MOUSE Transcription termination factor 2...2622e-16     87.8     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0006353; P:transcription termination, DNA-dependent; IEA:UniProtKB-KW.
179Q4IJ84    1154   RAD5_GIBZE DNA repair protein RAD5 OS=(Wheat ...1180.000000000000002     84.7     38     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
180Q6PCN7    1003   HLTF_MOUSE Helicase-like transcription factor...2290.000000000000007     82.8     30     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IDA:MGI.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
181O60177    1040   YG42_SCHPO Uncharacterized ATP-dependent heli...1513e-16     87.4     33     50GO:0016585; C:chromatin remodeling complex; ISS:PomBase.::GO:0000790; C:nuclear chromatin; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006338; P:chromatin remodeling; ISS:PomBase.::GO:0006281; P:DNA repair; ISS:PomBase.
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