Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFR034C
Length:
312
Number of sequences:
5887
Description:
YFR034C PHO4 SGDID:S000001930, Chr VI from 225958-225020, Genome Release 64-1-1, reverse complement, Verified ORF, "Basic helix-loop-helix (bHLH) transcription factor of the myc-family; activates transcription cooperatively with Pho2p in response to phosphate limitation; binding to 'CACGTG' motif is regulated by chromatin restriction, competitive binding of Cbf1p to the same DNA binding motif and cooperation with Pho2p,; function is regulated by phosphorylation at multiple sites and by phosphate availability"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P07270    312   PHO4_YEAST Phosphate system positive regulato...3120     640     100     100GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0043565; F:sequence-specific DNA binding; IDA:SGD.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:SGD.
GO:0016036; P:cellular response to phosphate starvation; IMP:SGD.::GO:0006338; P:chromatin remodeling; IMP:SGD.::GO:0006796; P:phosphate-containing compound metabolic process; TAS:SGD.::GO:0045937; P:positive regulation of phosphate metabolic process; IGI:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
2P20824    823   NUC1_NEUCR Phosphorus acquisition-controlling...950.001     44.7     34     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
3Q07957    307   USF1_XENBO Upstream stimulatory factor 1 OS=X...610.045     38.5     30     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
4Q15853    346   USF2_HUMAN Upstream stimulatory factor 2 OS=H...610.078     38.1     31     52GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0043425; F:bHLH transcription factor binding; IPI:BHF-UCL.::GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.::GO:0043565; F:sequence-specific DNA binding; IDA:BHF-UCL.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
GO:0019086; P:late viral mRNA transcription; IC:BHF-UCL.::GO:0055088; P:lipid homeostasis; ISS:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0000432; P:positive regulation of transcription from RNA polymerase II promoter by glucose; IMP:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
5Q9R210    475   TFEB_MOUSE Transcription factor EB OS=Mus mus...1830.098     37.7     25     44GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0001892; P:embryonic placenta development; IMP:UniProtKB.::GO:0006959; P:humoral immune response; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
6Q63665    346   USF2_RAT Upstream stimulatory factor 2 OS=Rat...610.12     37.4     31     52GO:0005634; C:nucleus; IDA:RGD.
GO:0003690; F:double-stranded DNA binding; IDA:RGD.::GO:0046982; F:protein heterodimerization activity; IMP:RGD.::GO:0042803; F:protein homodimerization activity; IMP:RGD.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:RGD.
7Q64705    346   USF2_MOUSE Upstream stimulatory factor 2 OS=M...610.12     37.4     31     52GO:0005634; C:nucleus; IDA:MGI.
GO:0007595; P:lactation; IMP:MGI.::GO:0055088; P:lipid homeostasis; IMP:BHF-UCL.::GO:0000432; P:positive regulation of transcription from RNA polymerase II promoter by glucose; IMP:BHF-UCL.
8P97309    243   MESP1_MOUSE Mesoderm posterior protein 1 OS=M...1170.13     37     30     46GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0035326; F:enhancer binding; IDA:BHF-UCL.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.
GO:0060913; P:cardiac cell fate determination; IDA:BHF-UCL.::GO:0003259; P:cardioblast anterior-lateral migration; IEP:BHF-UCL.::GO:0060975; P:cardioblast migration to the midline involved in heart field formation; IMP:BHF-UCL.::GO:0003241; P:growth involved in heart morphogenesis; IMP:BHF-UCL.::GO:0001947; P:heart looping; IMP:BHF-UCL.::GO:0048368; P:lateral mesoderm development; IEP:BHF-UCL.::GO:0008078; P:mesodermal cell migration; IGI:MGI.::GO:0042664; P:negative regulation of endodermal cell fate specification; IDA:BHF-UCL.::GO:0042662; P:negative regulation of mesodermal cell fate specification; IDA:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:BHF-UCL.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0090082; P:positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway; IDA:BHF-UCL.::GO:0070368; P:positive regulation of hepatocyte differentiation; IDA:BHF-UCL.::GO:0035481; P:positive regulation of Notch signaling pathway involved in heart induction; IDA:BHF-UCL.::GO:0051155; P:positive regulation of striated muscle cell differentiation; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0003139; P:secondary heart field specification; IDA:BHF-UCL.::GO:0023019; P:signal transduction involved in regulation of gene expression; IDA:MGI.::GO:0003236; P:sinus venosus morphogenesis; IMP:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
9O02818    310   USF1_RABIT Upstream stimulatory factor 1 OS=O...620.15     37     27     56
10Q6XBT4    310   USF1_BOVIN Upstream stimulatory factor 1 OS=B...620.16     37     27     56
11P22415    310   USF1_HUMAN Upstream stimulatory factor 1 OS=H...620.16     37     27     56GO:0005667; C:transcription factor complex; IDA:BHF-UCL.
GO:0043425; F:bHLH transcription factor binding; IPI:BHF-UCL.::GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.::GO:0043565; F:sequence-specific DNA binding; IDA:BHF-UCL.
GO:0032869; P:cellular response to insulin stimulus; IDA:BHF-UCL.::GO:0042593; P:glucose homeostasis; TAS:BHF-UCL.::GO:0019086; P:late viral mRNA transcription; IDA:BHF-UCL.::GO:0055088; P:lipid homeostasis; ISS:BHF-UCL.::GO:0051918; P:negative regulation of fibrinolysis; IC:BHF-UCL.::GO:0000432; P:positive regulation of transcription from RNA polymerase II promoter by glucose; IMP:BHF-UCL.::GO:0001666; P:response to hypoxia; IMP:BHF-UCL.::GO:0009411; P:response to UV; ISS:BHF-UCL.
12Q61069    310   USF1_MOUSE Upstream stimulatory factor 1 OS=M...620.19     36.6     27     56GO:0005667; C:transcription factor complex; IC:MGI.
GO:0003677; F:DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
GO:0055088; P:lipid homeostasis; IMP:BHF-UCL.::GO:0000432; P:positive regulation of transcription from RNA polymerase II promoter by glucose; IMP:BHF-UCL.::GO:0009411; P:response to UV; IMP:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
13C1DFK0    126   PAND_AZOVD Aspartate 1-decarboxylase OS=Azoto...410.25     35     41     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004068; F:aspartate 1-decarboxylase activity; IEA:EC.::GO:0005488; F:binding; IEA:InterPro.
GO:0006523; P:alanine biosynthetic process; IEA:InterPro.::GO:0015940; P:pantothenate biosynthetic process; IEA:UniProtKB-KW.
14P19484    476   TFEB_HUMAN Transcription factor EB OS=Homo sa...1220.3     36.2     25     46GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0001892; P:embryonic placenta development; ISS:UniProtKB.::GO:0006959; P:humoral immune response; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
15Q9STJ7    163   BH118_ARATH Transcription factor bHLH118 OS=A...560.4     35     36     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; TAS:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
16Q6QB00    270   HELT_DANRE Hairy and enhancer of split-relate...540.47     35.4     37     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
17Q02FU1    126   PAND_PSEAB Aspartate 1-decarboxylase OS=Pseud...411     33.1     37     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004068; F:aspartate 1-decarboxylase activity; IEA:EC.::GO:0005488; F:binding; IEA:InterPro.
GO:0006523; P:alanine biosynthetic process; IEA:InterPro.::GO:0015940; P:pantothenate biosynthetic process; IEA:UniProtKB-KW.
18B7V1E3    126   PAND_PSEA8 Aspartate 1-decarboxylase OS=Pseud...411     33.1     37     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004068; F:aspartate 1-decarboxylase activity; IEA:EC.::GO:0005488; F:binding; IEA:InterPro.
GO:0006523; P:alanine biosynthetic process; IEA:InterPro.::GO:0015940; P:pantothenate biosynthetic process; IEA:UniProtKB-KW.
19Q9HV68    126   PAND_PSEAE Aspartate 1-decarboxylase OS=12228...411     33.1     37     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004068; F:aspartate 1-decarboxylase activity; IEA:EC.::GO:0005488; F:binding; IEA:InterPro.
GO:0006523; P:alanine biosynthetic process; IEA:InterPro.::GO:0015940; P:pantothenate biosynthetic process; IEA:UniProtKB-KW.
20P53201    476   SWC4_YEAST SWR1-complex protein 4 OS=Saccharo...1031     34.7     18     49GO:0035267; C:NuA4 histone acetyltransferase complex; IPI:SGD.::GO:0000812; C:Swr1 complex; IDA:SGD.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006281; P:DNA repair; IDA:SGD.::GO:0034087; P:establishment of mitotic sister chromatid cohesion; IMP:SGD.::GO:0016573; P:histone acetylation; IPI:SGD.::GO:0043486; P:histone exchange; IPI:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
21Q64092    572   TFE3_MOUSE Transcription factor E3 OS=Mus mus...741.2     34.7     30     53GO:0005667; C:transcription factor complex; IC:MGI.
GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0006959; P:humoral immune response; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0045670; P:regulation of osteoclast differentiation; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
22A4VPM8    126   PAND_PSEU5 Aspartate 1-decarboxylase OS=Pseud...471.2     33.1     34     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004068; F:aspartate 1-decarboxylase activity; IEA:EC.::GO:0005488; F:binding; IEA:InterPro.
GO:0006523; P:alanine biosynthetic process; IEA:InterPro.::GO:0015940; P:pantothenate biosynthetic process; IEA:UniProtKB-KW.
23Q9NP71    852   MLXPL_HUMAN Carbohydrate-responsive element-b...641.3     34.7     34     50GO:0005829; C:cytosol; TAS:Reactome.::GO:0005667; C:transcription factor complex; NAS:UniProtKB.
GO:0035538; F:carbohydrate response element binding; TAS:BHF-UCL.::GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:BHF-UCL.::GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0055089; P:fatty acid homeostasis; ISS:UniProtKB.::GO:0010255; P:glucose mediated signaling pathway; ISS:BHF-UCL.::GO:0007243; P:intracellular protein kinase cascade; TAS:Reactome.::GO:0071157; P:negative regulation of cell cycle arrest; IMP:BHF-UCL.::GO:0090324; P:negative regulation of oxidative phosphorylation; IMP:BHF-UCL.::GO:0033137; P:negative regulation of peptidyl-serine phosphorylation; IMP:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:0045723; P:positive regulation of fatty acid biosynthetic process; ISS:BHF-UCL.::GO:0045821; P:positive regulation of glycolysis; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0070328; P:triglyceride homeostasis; NAS:BHF-UCL.
24Q8VIP2    865   MLXPL_RAT Carbohydrate-responsive element-bin...641.3     34.7     34     50GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0035538; F:carbohydrate response element binding; NAS:BHF-UCL.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:RGD.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:RGD.
GO:0071333; P:cellular response to glucose stimulus; IDA:BHF-UCL.::GO:0055089; P:fatty acid homeostasis; IMP:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; IMP:UniProtKB.::GO:0006110; P:regulation of glycolysis; IDA:RGD.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0006351; P:transcription, DNA-dependent; IDA:BHF-UCL.
25Q99MZ3    864   MLXPL_MOUSE Carbohydrate-responsive element-b...641.3     34.7     34     50GO:0005829; C:cytosol; TAS:Reactome.::GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0035538; F:carbohydrate response element binding; TAS:BHF-UCL.::GO:0008134; F:transcription factor binding; IDA:BHF-UCL.
GO:0055089; P:fatty acid homeostasis; ISS:UniProtKB.::GO:0010255; P:glucose mediated signaling pathway; IDA:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0045723; P:positive regulation of fatty acid biosynthetic process; IMP:BHF-UCL.::GO:0045821; P:positive regulation of glycolysis; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
26Q05B92    573   TFE3_BOVIN Transcription factor E3 OS=Bos tau...741.4     34.3     30     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
GO:0006959; P:humoral immune response; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
27P19532    575   TFE3_HUMAN Transcription factor E3 OS=Homo sa...741.4     34.3     30     53GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
GO:0006959; P:humoral immune response; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
28P49379    359   CBF1_KLULA Centromere-binding protein 1 OS=12...581.5     33.9     29     53GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
29Q7ZVS9    396   MYCB_DANRE Transcriptional regulator Myc-B OS...471.6     33.9     38     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
30Q10186    201   YAWC_SCHPO Uncharacterized bHLH domain-contai...581.8     33.1     29     53GO:0005634; C:nucleus; IDA:PomBase.
GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; ISS:PomBase.
GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:PomBase.
31Q9UH92    298   MLX_HUMAN Max-like protein X OS=Homo sapiens ...611.8     33.5     31     52GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003677; F:DNA binding; IDA:BHF-UCL.::GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:BHF-UCL.::GO:0031325; P:positive regulation of cellular metabolic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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