Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFR034C
Length:
312
Number of sequences:
5887
Description:
YFR034C PHO4 SGDID:S000001930, Chr VI from 225958-225020, Genome Release 64-1-1, reverse complement, Verified ORF, "Basic helix-loop-helix (bHLH) transcription factor of the myc-family; activates transcription cooperatively with Pho2p in response to phosphate limitation; binding to 'CACGTG' motif is regulated by chromatin restriction, competitive binding of Cbf1p to the same DNA binding motif and cooperation with Pho2p,; function is regulated by phosphorylation at multiple sites and by phosphate availability"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q9UH92    298   MLX_HUMAN Max-like protein X OS=Homo sapiens ...611.8     33.5     31     52GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003677; F:DNA binding; IDA:BHF-UCL.::GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:BHF-UCL.::GO:0031325; P:positive regulation of cellular metabolic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
32Q9BRJ9    268   MESP1_HUMAN Mesoderm posterior protein 1 OS=H...962.1     33.5     31     46GO:0005634; C:nucleus; IC:BHF-UCL.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
GO:0003210; P:cardiac atrium formation; IMP:BHF-UCL.::GO:0060913; P:cardiac cell fate determination; ISS:BHF-UCL.::GO:0060947; P:cardiac vascular smooth muscle cell differentiation; IMP:BHF-UCL.::GO:0003211; P:cardiac ventricle formation; IMP:BHF-UCL.::GO:0003259; P:cardioblast anterior-lateral migration; ISS:BHF-UCL.::GO:0060975; P:cardioblast migration to the midline involved in heart field formation; ISS:BHF-UCL.::GO:0045446; P:endothelial cell differentiation; IMP:BHF-UCL.::GO:0003241; P:growth involved in heart morphogenesis; ISS:BHF-UCL.::GO:0001947; P:heart looping; ISS:BHF-UCL.::GO:0048368; P:lateral mesoderm development; ISS:BHF-UCL.::GO:0042664; P:negative regulation of endodermal cell fate specification; ISS:BHF-UCL.::GO:0042662; P:negative regulation of mesodermal cell fate specification; ISS:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:BHF-UCL.::GO:0022008; P:neurogenesis; IMP:BHF-UCL.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0090082; P:positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway; ISS:BHF-UCL.::GO:0070368; P:positive regulation of hepatocyte differentiation; ISS:BHF-UCL.::GO:0051155; P:positive regulation of striated muscle cell differentiation; ISS:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0003139; P:secondary heart field specification; ISS:BHF-UCL.::GO:0060921; P:sinoatrial node cell differentiation; IMP:BHF-UCL.::GO:0003236; P:sinus venosus morphogenesis; ISS:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
33O61734    413   CYCL_DROME Protein cycle OS=Drosophila melano...602.2     33.5     25     60GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005667; C:transcription factor complex; IEA:InterPro.
GO:0003677; F:DNA binding; IDA:FlyBase.::GO:0046982; F:protein heterodimerization activity; IPI:FlyBase.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro.
GO:0048148; P:behavioral response to cocaine; NAS:FlyBase.::GO:0032922; P:circadian regulation of gene expression; IMP:FlyBase.::GO:0008062; P:eclosion rhythm; NAS:FlyBase.::GO:0045475; P:locomotor rhythm; NAS:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; NAS:FlyBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; NAS:FlyBase.::GO:0045187; P:regulation of circadian sleep/wake cycle, sleep; IMP:FlyBase.::GO:0042594; P:response to starvation; IDA:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
34O75030    526   MITF_HUMAN Microphthalmia-associated transcri...772.4     33.5     31     52GO:0005634; C:nucleus; NAS:UniProtKB.::GO:0043234; C:protein complex; IDA:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.
GO:0030318; P:melanocyte differentiation; NAS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006461; P:protein complex assembly; IDA:UniProtKB.
35P52161    165   MAX_DANRE Protein max OS=Danio rerio (Zebrafi...602.5     32.7     30     60GO:0071339; C:MLL1 complex; ISS:UniProtKB.
GO:0003677; F:DNA binding; NAS:UniProtKB.
GO:0006355; P:regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
36A6VCI7    126   PAND_PSEA7 Aspartate 1-decarboxylase OS=Pseud...412.8     32     34     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004068; F:aspartate 1-decarboxylase activity; IEA:EC.::GO:0005488; F:binding; IEA:InterPro.
GO:0006523; P:alanine biosynthetic process; IEA:InterPro.::GO:0015940; P:pantothenate biosynthetic process; IEA:UniProtKB-KW.
37Q7TS99    240   HELT_MOUSE Hairy and enhancer of split-relate...544     32.3     35     54GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0003677; F:DNA binding; IDA:MGI.::GO:0042803; F:protein homodimerization activity; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
GO:0007417; P:central nervous system development; IMP:MGI.::GO:0021858; P:GABAergic neuron differentiation in basal ganglia; IMP:MGI.::GO:0035264; P:multicellular organism growth; IMP:MGI.::GO:0010259; P:multicellular organismal aging; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0001967; P:suckling behavior; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
38Q8KCC0    878   MUTS_CHLTE DNA mismatch repair protein MutS O...944.1     33.1     22     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
39P41846    1009   WBS14_CAEEL Protein WBSCR14 homolog OS=Caenor...604.5     32.7     32     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
40Q08874    526   MITF_MOUSE Microphthalmia-associated transcri...774.9     32.7     31     52GO:0005634; C:nucleus; IDA:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003677; F:DNA binding; IDA:MGI.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:MGI.
GO:0046849; P:bone remodeling; IMP:MGI.::GO:0043010; P:camera-type eye development; IGI:MGI.::GO:0045165; P:cell fate commitment; IMP:MGI.::GO:0030318; P:melanocyte differentiation; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0030316; P:osteoclast differentiation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0042127; P:regulation of cell proliferation; IDA:MGI.::GO:0045670; P:regulation of osteoclast differentiation; IMP:MGI.::GO:0016055; P:Wnt receptor signaling pathway; IDA:MGI.
41Q8S3F1    320   BH020_ARATH Transcription factor NAI1 OS=Arab...565.9     32     34     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; TAS:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
42Q9HBZ2    717   ARNT2_HUMAN Aryl hydrocarbon receptor nuclear...776.6     32.3     26     48GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0017162; F:aryl hydrocarbon receptor binding; ISS:UniProtKB.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:InterPro.
GO:0007417; P:central nervous system development; ISS:UniProtKB.::GO:0001701; P:in utero embryonic development; ISS:UniProtKB.::GO:0001666; P:response to hypoxia; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
43Q78E60    712   ARNT2_RAT Aryl hydrocarbon receptor nuclear t...777     32.3     26     48GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IDA:RGD.::GO:0004871; F:signal transducer activity; IEA:InterPro.
GO:0043066; P:negative regulation of apoptotic process; IMP:RGD.::GO:0008284; P:positive regulation of cell proliferation; IMP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
44Q61324    712   ARNT2_MOUSE Aryl hydrocarbon receptor nuclear...777.5     32     26     48GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0017162; F:aryl hydrocarbon receptor binding; IPI:UniProtKB.::GO:0003677; F:DNA binding; IDA:MGI.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:InterPro.
GO:0007417; P:central nervous system development; IMP:UniProtKB.::GO:0001701; P:in utero embryonic development; IEP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0001666; P:response to hypoxia; TAS:UniProtKB.::GO:0009636; P:response to toxin; TAS:UniProtKB.::GO:0009410; P:response to xenobiotic stimulus; TAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
45A2T7L5    439   MYC_PONPY Myc proto-oncogene protein OS=Pongo...767.5     32     34     51GO:0005730; C:nucleolus; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; ISS:UniProtKB.
GO:0070888; F:E-box binding; ISS:UniProtKB.::GO:0032403; F:protein complex binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0006879; P:cellular iron ion homeostasis; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0000165; P:MAPK cascade; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0051782; P:negative regulation of cell division; ISS:UniProtKB.::GO:0045656; P:negative regulation of monocyte differentiation; ISS:UniProtKB.::GO:0032873; P:negative regulation of stress-activated MAPK cascade; ISS:UniProtKB.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:2000573; P:positive regulation of DNA biosynthetic process; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0048146; P:positive regulation of fibroblast proliferation; ISS:UniProtKB.::GO:2001022; P:positive regulation of response to DNA damage stimulus; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0032204; P:regulation of telomere maintenance; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; ISS:UniProtKB.::GO:0042493; P:response to drug; ISS:UniProtKB.::GO:0010332; P:response to gamma radiation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
46O88368    110   MITF_RAT Microphthalmia-associated transcript...778     30.4     31     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
47Q6YGZ4    851   CLOCK_TYTAL Circadian locomoter output cycles...838.3     32     27     51GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IEA:InterPro.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro.
GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
48Q8QGQ6    875   CLOCK_CHICK Circadian locomoter output cycles...838.4     32     27     51GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004871; F:signal transducer activity; IEA:InterPro.
49Q2VPU4    917   MLXIP_MOUSE MLX-interacting protein OS=Mus mu...578.5     32     37     47GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.
GO:0006913; P:nucleocytoplasmic transport; IDA:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
50P17106    351   CBF1_YEAST Centromere-binding protein 1 OS=Sa...588.8     31.6     29     52GO:0000775; C:chromosome, centromeric region; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0019237; F:centromeric DNA binding; IDA:SGD.::GO:0001102; F:RNA polymerase II activating transcription factor binding; IMP:SGD.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:SGD.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:SGD.::GO:0001103; F:RNA polymerase II repressing transcription factor binding; IDA:SGD.::GO:0001076; F:RNA polymerase II transcription factor binding transcription factor activity; IMP:SGD.
GO:0006338; P:chromatin remodeling; IDA:SGD.::GO:0007059; P:chromosome segregation; IMP:SGD.::GO:0006021; P:inositol biosynthetic process; IMP:SGD.::GO:0009086; P:methionine biosynthetic process; IMP:SGD.::GO:2000303; P:regulation of ceramide biosynthetic process; IMP:SGD.::GO:0061432; P:regulation of transcription from RNA polymerase II promoter in response to methionine; IMP:SGD.::GO:0000103; P:sulfate assimilation; IMP:SGD.
51O94855    1032   SC24D_HUMAN Protein transport protein Sec24D ...958.8     32     33     43GO:0030127; C:COPII vesicle coat; NAS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.::GO:0048208; P:COPII vesicle coating; TAS:Reactome.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0043687; P:post-translational protein modification; TAS:Reactome.::GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
52Q8WYA1    636   BMAL2_HUMAN Aryl hydrocarbon receptor nuclear...759.4     31.6     29     55GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005667; C:transcription factor complex; IEA:InterPro.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000982; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.::GO:0004871; F:signal transducer activity; IEA:InterPro.
GO:0007623; P:circadian rhythm; IDA:MGI.::GO:0009649; P:entrainment of circadian clock; NAS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
53O59678    166   RRS1_SCHPO Ribosome biogenesis regulatory pro...949.4     30.8     28     46GO:0005730; C:nucleolus; IDA:PomBase.
GO:0006364; P:rRNA processing; ISS:PomBase.
54Q9SVU7    445   BH056_ARATH Putative transcription factor bHL...839.7     31.6     31     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; TAS:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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