rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q00684 | 551 | CDC14_YEAST Tyrosine-protein phosphatase CDC1... | 551 | 0 | 1154 | 100 | 100 | GO:0030869; C:RENT complex; IDA:SGD.::GO:0005816; C:spindle pole body; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0000278; P:mitotic cell cycle; IMP:SGD.::GO:0007096; P:regulation of exit from mitosis; IGI:SGD. | 2 | Q9P7H1 | 537 | FLP1_SCHPO Tyrosine-protein phosphatase CDC14... | 492 | 1e-127 | 391 | 44 | 59 | GO:0000777; C:condensed chromosome kinetochore; IDA:PomBase.::GO:0031097; C:medial cortex; IDA:PomBase.::GO:0005730; C:nucleolus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0004864; F:protein phosphatase inhibitor activity; IGI:PomBase.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0008608; P:attachment of spindle microtubules to kinetochore; IGI:PomBase.::GO:0071937; P:barrier septum assembly involved in cell cycle cytokinesis; IMP:PomBase.::GO:0035853; P:chromosome passenger complex localization to spindle midzone; IMP:PomBase.::GO:0031566; P:contractile ring maintenance involved in cell cycle cytokinesis; IMP:PomBase.::GO:0031565; P:cytokinesis checkpoint; IMP:PomBase.::GO:0045736; P:negative regulation of cyclin-dependent protein kinase activity; IGI:PomBase.::GO:0031031; P:positive regulation of septation initiation signaling cascade; TAS:PomBase.::GO:0007096; P:regulation of exit from mitosis; IMP:PomBase.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IMP:PomBase.::GO:0031134; P:sister chromatid biorientation; IMP:PomBase. | 3 | Q6GQT0 | 603 | CC14A_MOUSE Dual specificity protein phosphat... | 389 | 4e-74 | 253 | 35 | 56 | GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 4 | Q9UNH5 | 594 | CC14A_HUMAN Dual specificity protein phosphat... | 325 | 2e-70 | 243 | 37 | 58 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:HGNC.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; TAS:ProtInc. | 5 | O60729 | 498 | CC14B_HUMAN Dual specificity protein phosphat... | 333 | 4e-70 | 239 | 37 | 57 | GO:0005730; C:nucleolus; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0051488; P:activation of anaphase-promoting complex activity; IMP:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; IDA:UniProtKB. | 6 | A4D256 | 554 | CC14C_HUMAN Dual specificity protein phosphat... | 311 | 6e-69 | 238 | 38 | 59 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 7 | Q6PFY9 | 485 | CC14B_MOUSE Dual specificity protein phosphat... | 397 | 8e-69 | 236 | 35 | 53 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0051488; P:activation of anaphase-promoting complex activity; ISS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB. | 8 | A6N3Q4 | 483 | CC14C_HYLSY Dual specificity protein phosphat... | 331 | 1e-68 | 235 | 38 | 57 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 9 | P81299 | 1063 | CDC14_CAEEL Probable tyrosine-protein phospha... | 351 | 4e-52 | 196 | 33 | 51 | GO:0000235; C:astral microtubule; IDA:WormBase.::GO:0005813; C:centrosome; IDA:WormBase.::GO:0030496; C:midbody; IDA:WormBase.::GO:0005730; C:nucleolus; IDA:WormBase.::GO:0051233; C:spindle midzone; IDA:WormBase. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; TAS:UniProtKB.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0000910; P:cytokinesis; IMP:UniProtKB.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0071850; P:mitotic cell cycle arrest; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0060284; P:regulation of cell development; IMP:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IMP:WormBase. | 10 | A1L1R5 | 713 | PTPC1_DANRE Protein tyrosine phosphatase doma... | 88 | 0.00000009 | 58.5 | 35 | 55 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 11 | Q6NZK8 | 747 | PTPC1_MOUSE Protein tyrosine phosphatase doma... | 88 | 0.0000002 | 57.8 | 35 | 55 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 12 | A2A3K4 | 754 | PTPC1_HUMAN Protein tyrosine phosphatase doma... | 88 | 0.0000002 | 57.8 | 34 | 55 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 13 | A7E379 | 796 | PTPC1_BOVIN Protein tyrosine phosphatase doma... | 88 | 0.0000002 | 57.8 | 34 | 55 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 14 | Q9BVJ7 | 150 | DUS23_HUMAN Dual specificity protein phosphat... | 106 | 0.0000004 | 53.5 | 28 | 46 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 15 | Q6P9X4 | 167 | TP4A2_RAT Protein tyrosine phosphatase type I... | 136 | 0.0000006 | 53.1 | 31 | 45 | GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 16 | O70274 | 167 | TP4A2_MOUSE Protein tyrosine phosphatase type... | 136 | 0.0000006 | 53.1 | 31 | 45 | GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 17 | Q12974 | 167 | TP4A2_HUMAN Protein tyrosine phosphatase type... | 136 | 0.0000006 | 53.1 | 31 | 45 | GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004727; F:prenylated protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | | 18 | Q9D658 | 173 | TP4A3_MOUSE Protein tyrosine phosphatase type... | 106 | 0.0000007 | 53.1 | 34 | 50 | GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 19 | Q54DU9 | 166 | TP4AA_DICDI Probable protein tyrosine phospha... | 147 | 0.0000009 | 52.8 | 29 | 44 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 20 | A2VDT1 | 173 | TP4A3_BOVIN Protein tyrosine phosphatase type... | 124 | 0.0000009 | 52.8 | 30 | 44 | GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 21 | Q78EG7 | 173 | TP4A1_RAT Protein tyrosine phosphatase type I... | 134 | 0.000002 | 51.6 | 31 | 43 | GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:RGD.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IDA:RGD. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 22 | Q63739 | 173 | TP4A1_MOUSE Protein tyrosine phosphatase type... | 134 | 0.000002 | 51.6 | 31 | 43 | GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004727; F:prenylated protein tyrosine phosphatase activity; TAS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB. | 23 | Q9TSM6 | 173 | TP4A1_MACFA Protein tyrosine phosphatase type... | 134 | 0.000002 | 51.6 | 31 | 43 | GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 24 | Q93096 | 173 | TP4A1_HUMAN Protein tyrosine phosphatase type... | 134 | 0.000002 | 51.6 | 31 | 43 | GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; NAS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 25 | O75365 | 173 | TP4A3_HUMAN Protein tyrosine phosphatase type... | 106 | 0.000003 | 51.2 | 34 | 50 | GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004727; F:prenylated protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | | 26 | Q5R7J8 | 173 | TP4A1_PONAB Protein tyrosine phosphatase type... | 134 | 0.000003 | 50.8 | 31 | 43 | GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 27 | Q6NT99 | 150 | DUS23_MOUSE Dual specificity protein phosphat... | 106 | 0.000007 | 49.7 | 27 | 44 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 28 | Q9PUT6 | 402 | PTEN_XENLA Phosphatidylinositol 3,4,5-trispho... | 88 | 0.00001 | 51.2 | 32 | 53 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051717; F:inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.::GO:0016314; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0051800; F:phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; ISS:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0046855; P:inositol phosphate dephosphorylation; ISS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0051895; P:negative regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0010975; P:regulation of neuron projection development; ISS:UniProtKB.::GO:0031647; P:regulation of protein stability; ISS:UniProtKB. | 29 | Q9D700 | 211 | DUS26_MOUSE Dual specificity protein phosphat... | 106 | 0.00006 | 47.8 | 33 | 50 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; ISS:MGI. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | | 30 | O08586 | 403 | PTEN_MOUSE Phosphatidylinositol 3,4,5-trispho... | 89 | 0.0001 | 48.1 | 31 | 51 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0035749; C:myelin sheath adaxonal region; IDA:BHF-UCL.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0043220; C:Schmidt-Lanterman incisure; IDA:BHF-UCL.::GO:0019717; C:synaptosome; IDA:BHF-UCL. | | | | | | | | | | GO:0051717; F:inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.::GO:0016314; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0051800; F:phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0007092; P:activation of mitotic anaphase-promoting complex activity; IMP:BHF-UCL.::GO:0001525; P:angiogenesis; IMP:MGI.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0048738; P:cardiac muscle tissue development; IMP:MGI.::GO:0032286; P:central nervous system myelin maintenance; IMP:BHF-UCL.::GO:0021955; P:central nervous system neuron axonogenesis; IMP:BHF-UCL.::GO:0060997; P:dendritic spine morphogenesis; IMP:BHF-UCL.::GO:0021542; P:dentate gyrus development; IMP:BHF-UCL.::GO:0043542; P:endothelial cell migration; IMP:MGI.::GO:0048853; P:forebrain morphogenesis; IMP:BHF-UCL.::GO:0006917; P:induction of apoptosis; IMP:MGI.::GO:0046855; P:inositol phosphate dephosphorylation; ISS:UniProtKB.::GO:0007611; P:learning or memory; IMP:BHF-UCL.::GO:0045475; P:locomotor rhythm; IMP:BHF-UCL.::GO:0060291; P:long-term synaptic potentiation; IMP:BHF-UCL.::GO:0060179; P:male mating behavior; IMP:BHF-UCL.::GO:0042711; P:maternal behavior; IMP:BHF-UCL.::GO:0033555; P:multicellular organismal response to stress; IMP:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0050771; P:negative regulation of axonogenesis; IMP:BHF-UCL.::GO:0090344; P:negative regulation of cell aging; IMP:BHF-UCL.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0045792; P:negative regulation of cell size; IMP:BHF-UCL.::GO:0061002; P:negative regulation of dendritic spine morphogenesis; IMP:BHF-UCL.::GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:MGI.::GO:0090394; P:negative regulation of excitatory postsynaptic membrane potential; IMP:BHF-UCL.::GO:0051895; P:negative regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0031642; P:negative regulation of myelination; IMP:MGI.::GO:0046621; P:negative regulation of organ growth; IMP:BHF-UCL.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0090071; P:negative regulation of ribosome biogenesis; IMP:BHF-UCL.::GO:2000808; P:negative regulation of synaptic vesicle clustering; IMP:BHF-UCL.::GO:0007270; P:neuron-neuron synaptic transmission; IMP:BHF-UCL.::GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; IMP:BHF-UCL.::GO:0097107; P:postsynaptic density assembly; IMP:BHF-UCL.::GO:0060134; P:prepulse inhibition; IMP:BHF-UCL.::GO:0097105; P:presynaptic membrane assembly; IMP:BHF-UCL.::GO:0060736; P:prostate gland growth; IMP:MGI.::GO:0043491; P:protein kinase B signaling cascade; IMP:UniProtKB.::GO:0002902; P:regulation of B cell apoptotic process; IMP:MGI.::GO:0033032; P:regulation of myeloid cell apoptotic process; IMP:MGI.::GO:0060024; P:rhythmic synaptic transmission; IMP:BHF-UCL.::GO:0035176; P:social behavior; IMP:BHF-UCL.::GO:0060074; P:synapse maturation; IMP:BHF-UCL. | 31 | P60484 | 403 | PTEN_HUMAN Phosphatidylinositol 3,4,5-trispho... | 89 | 0.0001 | 48.1 | 31 | 51 | GO:0042995; C:cell projection; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB.::GO:0035749; C:myelin sheath adaxonal region; ISS:BHF-UCL.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0043220; C:Schmidt-Lanterman incisure; ISS:BHF-UCL.::GO:0019717; C:synaptosome; ISS:BHF-UCL. | | | | | | | | | | GO:0010997; F:anaphase-promoting complex binding; IPI:BHF-UCL.::GO:0051717; F:inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity; IDA:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030165; F:PDZ domain binding; IPI:UniProtKB.::GO:0016314; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; IDA:UniProtKB.::GO:0051800; F:phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity; IDA:UniProtKB.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; IDA:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0007092; P:activation of mitotic anaphase-promoting complex activity; IDA:BHF-UCL.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0060070; P:canonical Wnt receptor signaling pathway; IDA:BHF-UCL.::GO:0008283; P:cell proliferation; TAS:UniProtKB.::GO:0032286; P:central nervous system myelin maintenance; ISS:BHF-UCL.::GO:0021955; P:central nervous system neuron axonogenesis; ISS:BHF-UCL.::GO:0060997; P:dendritic spine morphogenesis; ISS:BHF-UCL.::GO:0021542; P:dentate gyrus development; ISS:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0048853; P:forebrain morphogenesis; ISS:BHF-UCL.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0046855; P:inositol phosphate dephosphorylation; IDA:UniProtKB.::GO:0007611; P:learning or memory; ISS:BHF-UCL.::GO:0045475; P:locomotor rhythm; ISS:BHF-UCL.::GO:0033555; P:multicellular organismal response to stress; ISS:BHF-UCL.::GO:0050771; P:negative regulation of axonogenesis; ISS:BHF-UCL.::GO:0030336; P:negative regulation of cell migration; IMP:UniProtKB.::GO:0045792; P:negative regulation of cell size; ISS:BHF-UCL.::GO:0031658; P:negative regulation of cyclin-dependent protein kinase activity involved in G1/S; IDA:BHF-UCL.::GO:0061002; P:negative regulation of dendritic spine morphogenesis; ISS:BHF-UCL.::GO:0090394; P:negative regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.::GO:0051895; P:negative regulation of focal adhesion assembly; IMP:UniProtKB.::GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IDA:BHF-UCL.::GO:0046621; P:negative regulation of organ growth; ISS:BHF-UCL.::GO:0014067; P:negative regulation of phosphatidylinositol 3-kinase cascade; TAS:BHF-UCL.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0001933; P:negative regulation of protein phosphorylation; IDA:BHF-UCL.::GO:2000808; P:negative regulation of synaptic vesicle clustering; ISS:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007270; P:neuron-neuron synaptic transmission; ISS:BHF-UCL.::GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0008284; P:positive regulation of cell proliferation; ISS:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.::GO:0097107; P:postsynaptic density assembly; ISS:BHF-UCL.::GO:0060134; P:prepulse inhibition; ISS:BHF-UCL.::GO:0097105; P:presynaptic membrane assembly; ISS:BHF-UCL.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0050821; P:protein stabilization; IDA:BHF-UCL.::GO:0060024; P:rhythmic synaptic transmission; ISS:BHF-UCL.::GO:0035176; P:social behavior; ISS:BHF-UCL.::GO:0060074; P:synapse maturation; ISS:BHF-UCL.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. |