rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | Q8I1C0 | 369 | SH3G3_DROPS Endophilin-A OS=Drosophila pseudo... | 66 | 0.00000005 | 58.2 | 41 | 59 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042171; F:lysophosphatidic acid acyltransferase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050803; P:regulation of synapse structure and activity; ISS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; ISS:UniProtKB. | 62 | Q6C2N2 | 685 | HSE1_YARLI Class E vacuolar protein-sorting m... | 62 | 0.00000005 | 58.9 | 45 | 58 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 63 | Q0U6X7 | 618 | HSE1_PHANO Class E vacuolar protein-sorting m... | 51 | 0.00000007 | 58.5 | 49 | 63 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 64 | Q8BZT2 | 735 | SH3R2_MOUSE Putative E3 ubiquitin-protein lig... | 53 | 0.1 | 38.9 | 38 | 60 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008157; F:protein phosphatase 1 binding; ISS:UniProtKB.::GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 65 | Q8I190 | 369 | SH3G3_DROVI Endophilin-A OS=Drosophila virili... | 66 | 0.00000007 | 57.8 | 41 | 59 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042171; F:lysophosphatidic acid acyltransferase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050803; P:regulation of synapse structure and activity; ISS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; ISS:UniProtKB. | 66 | P47941 | 303 | CRKL_MOUSE Crk-like protein OS=Mus musculus (... | 40 | 2.7 | 33.9 | 35 | 60 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0009952; P:anterior/posterior pattern specification; IGI:MGI.::GO:0001568; P:blood vessel development; IGI:MGI.::GO:0007507; P:heart development; IGI:MGI.::GO:0009887; P:organ morphogenesis; IMP:MGI.::GO:0060017; P:parathyroid gland development; IGI:MGI.::GO:0048538; P:thymus development; IGI:MGI. | 67 | Q75DS3 | 443 | HSE1_ASHGO Class E vacuolar protein-sorting m... | 92 | 0.00000007 | 58.2 | 34 | 50 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 68 | Q6ZMT1 | 411 | STAC2_HUMAN SH3 and cysteine-rich domain-cont... | 89 | 0.00000008 | 57.8 | 37 | 49 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 69 | P38753 | 452 | HSE1_YEAST Class E vacuolar protein-sorting m... | 50 | 0.00000008 | 58.2 | 52 | 62 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0033565; C:ESCRT-0 complex; IPI:SGD. | | | | | | | | | | GO:0043130; F:ubiquitin binding; IDA:SGD. | | | | | | | | | | GO:0045324; P:late endosome to vacuole transport; IMP:SGD.::GO:0006623; P:protein targeting to vacuole; IMP:SGD. | 70 | Q6FN49 | 450 | HSE1_CANGA Class E vacuolar protein-sorting m... | 50 | 0.00000008 | 57.8 | 50 | 64 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 71 | Q99961 | 368 | SH3G1_HUMAN Endophilin-A2 OS=Homo sapiens (Hu... | 84 | 0.00000008 | 57.8 | 35 | 58 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:ProtInc. | 72 | Q99963 | 347 | SH3G3_HUMAN Endophilin-A3 OS=Homo sapiens (Hu... | 85 | 0.00000009 | 57.4 | 36 | 54 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:ProtInc. | 73 | A5D8S5 | 867 | SH3R1_DANRE E3 ubiquitin-protein ligase SH3RF... | 53 | 0.5 | 36.6 | 28 | 60 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 74 | Q5HYK7 | 790 | SH319_HUMAN SH3 domain-containing protein 19 ... | 56 | 0.0001 | 48.5 | 43 | 66 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:BHF-UCL. | | | | | | | | | | GO:0070064; F:proline-rich region binding; IPI:BHF-UCL. | | | | | | | | | | GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IMP:BHF-UCL.::GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.::GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB. | 75 | Q2KJA1 | 368 | SH3G1_BOVIN Endophilin-A2 OS=Bos taurus (Bovi... | 84 | 0.0000001 | 57.4 | 33 | 58 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 76 | O35964 | 368 | SH3G1_RAT Endophilin-A2 OS=Rattus norvegicus ... | 69 | 0.0000001 | 57 | 36 | 59 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0051020; F:GTPase binding; IPI:RGD.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0019902; F:phosphatase binding; IPI:RGD. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 77 | Q5U2U2 | 303 | CRKL_RAT Crk-like protein OS=Rattus norvegicu... | 40 | 2.7 | 33.9 | 35 | 60 | | | | | | | | | | | | | | | | | | | | | | 78 | Q8R1B0 | 408 | STAC2_MOUSE SH3 and cysteine-rich domain-cont... | 54 | 0.0000001 | 57 | 46 | 63 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 79 | Q9NZM3 | 1697 | ITSN2_HUMAN Intersectin-2 OS=Homo sapiens (Hu... | 51 | 0.009 | 42.4 | 37 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 80 | A6QLK6 | 217 | GRAP_BOVIN GRB2-related adapter protein OS=Bo... | 71 | 0.0000005 | 53.9 | 37 | 56 | | | | | | | | | | | | | | | | | | | | | | 81 | Q06449 | 215 | PIN3_YEAST [PSI+] inducibility protein 3 OS=S... | 66 | 0.0000002 | 55.1 | 41 | 61 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IPI:SGD. | 82 | O35180 | 347 | SH3G3_RAT Endophilin-A3 OS=Rattus norvegicus ... | 73 | 0.0000002 | 56.2 | 37 | 55 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 83 | Q8T390 | 369 | SH3G3_DROME Endophilin-A OS=Drosophila melano... | 52 | 0.0000002 | 56.2 | 46 | 69 | GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042171; F:lysophosphatidic acid acyltransferase activity; IDA:FlyBase. | | | | | | | | | | GO:0007269; P:neurotransmitter secretion; NAS:FlyBase.::GO:0050803; P:regulation of synapse structure and activity; IMP:FlyBase.::GO:0048488; P:synaptic vesicle endocytosis; IMP:FlyBase. | 84 | Q8I1I3 | 369 | SH3G3_DROER Endophilin-A OS=Drosophila erecta... | 52 | 0.0000002 | 56.2 | 46 | 69 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042171; F:lysophosphatidic acid acyltransferase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050803; P:regulation of synapse structure and activity; ISS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; ISS:UniProtKB. | 85 | Q07883 | 217 | GRB2_CHICK Growth factor receptor-bound prote... | 55 | 0.00006 | 47.8 | 35 | 60 | GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | | 86 | Q498M5 | 735 | SH3R2_RAT Putative E3 ubiquitin-protein ligas... | 61 | 0.095 | 38.9 | 36 | 51 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008157; F:protein phosphatase 1 binding; ISS:UniProtKB.::GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 87 | P14317 | 486 | HCLS1_HUMAN Hematopoietic lineage cell-specif... | 55 | 0.0000003 | 56.2 | 49 | 65 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc. | | | | | | | | | | GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; TAS:ProtInc.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; ISS:UniProtKB.::GO:0009725; P:response to hormone stimulus; ISS:UniProtKB. | 88 | Q6BNP6 | 512 | HSE1_DEBHA Class E vacuolar protein-sorting m... | 77 | 0.0000003 | 56.2 | 44 | 55 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 89 | Q8IVI9 | 506 | NOSTN_HUMAN Nostrin OS=Homo sapiens (Human). ... | 64 | 0.0000003 | 56.2 | 42 | 58 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0046209; P:nitric oxide metabolic process; TAS:Reactome.::GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 90 | O89100 | 322 | GRAP2_MOUSE GRB2-related adaptor protein 2 OS... | 55 | 0.28 | 37 | 29 | 53 | GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | | 91 | Q8TC17 | 118 | GRAPL_HUMAN GRB2-related adapter protein-like... | 55 | 0.0000004 | 52.8 | 45 | 60 | | | | | | | | | | | | | | | | | | | | | |