Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFR024C-A
Length:
459
Number of sequences:
5887
Description:
YFR024C-A LSB3 SGDID:S000002968, Chr VI from 203292-201960,203433-203387, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein containing a C-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
541Q6CVE9    1260   MYO1_KLULA Myosin-1 OS=1267 / NRRL Y-1140 / W...570.93     35.8     40     53GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
542A1X283    911   SPD2B_HUMAN SH3 and PX domain-containing prot...541.1     35.4     26     54GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0002102; C:podosome; ISS:UniProtKB.
GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; ISS:UniProtKB.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB.::GO:0010314; F:phosphatidylinositol-5-phosphate binding; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB.
GO:0060612; P:adipose tissue development; ISS:UniProtKB.::GO:0060348; P:bone development; IMP:UniProtKB.::GO:0007154; P:cell communication; IEA:InterPro.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0022617; P:extracellular matrix disassembly; IMP:UniProtKB.::GO:0001654; P:eye development; IMP:UniProtKB.::GO:0007507; P:heart development; IMP:UniProtKB.::GO:0071800; P:podosome assembly; ISS:UniProtKB.::GO:0072657; P:protein localization in membrane; IDA:UniProtKB.::GO:0006801; P:superoxide metabolic process; IDA:UniProtKB.
543P70290    466   EM55_MOUSE 55 kDa erythrocyte membrane protei...281.2     35.4     54     64GO:0030863; C:cortical cytoskeleton; IDA:MGI.::GO:0016020; C:membrane; IDA:MGI.::GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0090022; P:regulation of neutrophil chemotaxis; IMP:UniProtKB.
544A8N2Y6    1277   MYO1_COPC7 Myosin-1 OS=9003) (Inky cap fungus...531.2     35.4     32     57GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
545A9CB74    466   EM55_PAPAN 55 kDa erythrocyte membrane protei...281.2     35     54     64GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell.
GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0090022; P:regulation of neutrophil chemotaxis; ISS:UniProtKB.
546Q00013    466   EM55_HUMAN 55 kDa erythrocyte membrane protei...281.2     35     54     64GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell.
GO:0004385; F:guanylate kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0090022; P:regulation of neutrophil chemotaxis; ISS:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc.
547A2AAY5    908   SPD2B_MOUSE SH3 and PX domain-containing prot...541.2     35.4     26     54GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0002102; C:podosome; IDA:UniProtKB.
GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IDA:UniProtKB.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; IMP:UniProtKB.::GO:0070273; F:phosphatidylinositol-4-phosphate binding; IDA:UniProtKB.::GO:0010314; F:phosphatidylinositol-5-phosphate binding; IDA:UniProtKB.::GO:0042169; F:SH2 domain binding; IDA:UniProtKB.
GO:0060612; P:adipose tissue development; IMP:UniProtKB.::GO:0060348; P:bone development; IMP:UniProtKB.::GO:0007154; P:cell communication; IEA:InterPro.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0001654; P:eye development; IMP:UniProtKB.::GO:0007507; P:heart development; IMP:UniProtKB.::GO:0071800; P:podosome assembly; IMP:UniProtKB.::GO:0045600; P:positive regulation of fat cell differentiation; IMP:UniProtKB.::GO:0072657; P:protein localization in membrane; ISS:UniProtKB.::GO:0006801; P:superoxide metabolic process; ISS:UniProtKB.
548Q2US45    1261   MYO1_ASPOR Myosin-1 OS=Aspergillus oryzae (st...551.2     35.4     36     47GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
549Q5RDW4    466   EM55_PONAB 55 kDa erythrocyte membrane protei...281.2     35     54     64GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell.
GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0090022; P:regulation of neutrophil chemotaxis; ISS:UniProtKB.
550Q8WV41    574   SNX33_HUMAN Sorting nexin-33 OS=Homo sapiens ...571.2     35.4     33     56
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007154; P:cell communication; IEA:InterPro.
551Q9H7D0    1870   DOCK5_HUMAN Dedicator of cytokinesis protein ...611.2     35.4     26     51GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB.
552Q6GPD0    1940   RHG32_XENLA Rho GTPase-activating protein 32 ...561.4     35.4     25     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
553A7TDZ8    1214   MYO1_VANPO Myosin-1 OS=(Kluyveromyces polyspo...611.4     35.4     38     51GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
554A1IGU5    675   ARH37_HUMAN Rho guanine nucleotide exchange f...751.5     35     27     49GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
555O89032    1124   SPD2A_MOUSE SH3 and PX domain-containing prot...547.3     33.1     28     54GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0002102; C:podosome; ISS:UniProtKB.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007154; P:cell communication; IEA:InterPro.
556Q6CHN0    1136   SLA1_YARLI Actin cytoskeleton-regulatory comp...601.7     35     35     53GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
557Q92608    1830   DOCK2_HUMAN Dedicator of cytokinesis protein ...681.7     35     28     50GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IDA:UniProtKB.::GO:0042608; F:T cell receptor binding; IDA:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; TAS:UniProtKB.::GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
558Q5TCZ1    1133   SPD2A_HUMAN SH3 and PX domain-containing prot...547     33.1     28     54GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0002102; C:podosome; IDA:UniProtKB.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0006801; P:superoxide metabolic process; IDA:UniProtKB.
559Q62915    909   CSKP_RAT Peripheral plasma membrane protein C...371.7     35     41     62GO:0060170; C:cilium membrane; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030425; C:dendrite; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0042734; C:presynaptic membrane; IDA:BHF-UCL.::GO:0043234; C:protein complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; TAS:RGD.::GO:0004683; F:calmodulin-dependent protein kinase activity; TAS:RGD.::GO:0030165; F:PDZ domain binding; IPI:RGD.::GO:0008022; F:protein C-terminus binding; IMP:RGD.::GO:0032403; F:protein complex binding; IPI:RGD.::GO:0003713; F:transcription coactivator activity; TAS:RGD.
GO:0006886; P:intracellular protein transport; IMP:RGD.::GO:0006461; P:protein complex assembly; TAS:RGD.
560C4QVD6    273   SHO1_PICPG High osmolarity signaling protein ...541.9     34.3     35     56GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
561Q8IZD9    2030   DOCK3_HUMAN Dedicator of cytokinesis protein ...651.9     35     31     48GO:0005737; C:cytoplasm; IDA:HPA.
GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
562Q8VCM2    349   NOXO1_MOUSE NADPH oxidase organizer 1 OS=Mus ...482     34.3     33     52
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0016176; F:superoxide-generating NADPH oxidase activator activity; IDA:MGI.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0022617; P:extracellular matrix disassembly; ISS:UniProtKB.::GO:0006801; P:superoxide metabolic process; IDA:MGI.
563O14559    1287   RHG33_HUMAN Rho GTPase-activating protein 33 ...552     34.7     25     53
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
564Q5U2Y3    576   MPP7_RAT MAGUK p55 subfamily member 7 OS=Ratt...892     34.7     28     43GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
565P24135    1265   PLCG2_RAT 1-phosphatidylinositol 4,5-bisphosp...622.2     34.7     34     48GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:RGD.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:RGD.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006661; P:phosphatidylinositol biosynthetic process; ISS:UniProtKB.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0051209; P:release of sequestered calcium ion into cytosol; ISS:UniProtKB.::GO:0033198; P:response to ATP; IDA:RGD.::GO:0032026; P:response to magnesium ion; IDA:RGD.
566Q8CIH5    1265   PLCG2_MOUSE 1-phosphatidylinositol 4,5-bispho...622.3     34.7     34     48GO:0005829; C:cytosol; IMP:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0004435; F:phosphatidylinositol phospholipase C activity; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0032237; P:activation of store-operated calcium channel activity; IMP:MGI.::GO:0050853; P:B cell receptor signaling pathway; IMP:UniProtKB.::GO:0002316; P:follicular B cell differentiation; IMP:MGI.::GO:0032959; P:inositol trisphosphate biosynthetic process; IDA:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043069; P:negative regulation of programmed cell death; IMP:MGI.::GO:0006661; P:phosphatidylinositol biosynthetic process; ISS:UniProtKB.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0010468; P:regulation of gene expression; IMP:MGI.::GO:0051209; P:release of sequestered calcium ion into cytosol; IMP:UniProtKB.::GO:0032496; P:response to lipopolysaccharide; IDA:MGI.::GO:0050852; P:T cell receptor signaling pathway; IDA:MGI.
567Q80YF9    1305   RHG33_MOUSE Rho GTPase-activating protein 33 ...492.6     34.3     27     55GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; IDA:MGI.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
568P16885    1265   PLCG2_HUMAN 1-phosphatidylinositol 4,5-bispho...622.6     34.3     34     48GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0019722; P:calcium-mediated signaling; NAS:UniProtKB.::GO:0006661; P:phosphatidylinositol biosynthetic process; IDA:UniProtKB.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0051209; P:release of sequestered calcium ion into cytosol; IDA:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; TAS:UniProtKB.
569Q32LM0    365   SHLB1_BOVIN Endophilin-B1 OS=Bos taurus (Bovi...582.7     33.9     29     47GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
570Q9H6Q3    261   SLAP2_HUMAN Src-like-adapter 2 OS=Homo sapien...702.8     33.5     34     47GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; NAS:UniProtKB.::GO:0005886; C:plasma membrane; TAS:UniProtKB.
GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0005070; F:SH3/SH2 adaptor activity; IDA:UniProtKB.
GO:0050851; P:antigen receptor-mediated signaling pathway; TAS:UniProtKB.::GO:0019724; P:B cell mediated immunity; TAS:UniProtKB.::GO:0030522; P:intracellular receptor mediated signaling pathway; TAS:UniProtKB.::GO:0050869; P:negative regulation of B cell activation; TAS:UniProtKB.::GO:0050849; P:negative regulation of calcium-mediated signaling; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0042110; P:T cell activation; TAS:UniProtKB.
571Q07533    885   CYK3_YEAST Cytokinesis protein 3 OS=Saccharom...592.9     34.3     32     56GO:0000142; C:cellular bud neck contractile ring; IDA:SGD.
GO:0071937; P:barrier septum assembly involved in cell cycle cytokinesis; IPI:SGD.
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