rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
511 | Q62077 | 1302 | PLCG1_MOUSE 1-phosphatidylinositol 4,5-bispho... | 68 | 0.37 | 37 | 32 | 51 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0035254; F:glutamate receptor binding; IPI:MGI.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IDA:MGI. | 512 | Q9QX74 | 1474 | SHAN2_RAT SH3 and multiple ankyrin repeat dom... | 54 | 0.37 | 37 | 33 | 52 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0060170; C:cilium membrane; IDA:BHF-UCL.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030426; C:growth cone; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0014069; C:postsynaptic density; IDA:RGD.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035255; F:ionotropic glutamate receptor binding; ISS:BHF-UCL.::GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0017124; F:SH3 domain binding; IPI:RGD. | | | | | | | | | | GO:0007420; P:brain development; IEP:RGD. | 513 | Q8AXQ3 | 966 | SH3B4_SERQU SH3 domain-binding protein 4 OS=S... | 89 | 0.38 | 37 | 30 | 45 | GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 514 | B6QEE0 | 282 | SHO1_PENMQ High osmolarity signaling protein ... | 59 | 0.4 | 36.2 | 37 | 58 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 515 | B2RQE8 | 841 | RHG42_MOUSE Rho GTPase-activating protein 42 ... | 59 | 0.4 | 37 | 34 | 51 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 516 | Q9NR46 | 395 | SHLB2_HUMAN Endophilin-B2 OS=Homo sapiens (Hu... | 62 | 0.41 | 36.6 | 27 | 48 | GO:0005737; C:cytoplasm; IDA:HGNC.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 517 | Q8R3V5 | 400 | SHLB2_MOUSE Endophilin-B2 OS=Mus musculus (Mo... | 62 | 0.42 | 36.6 | 27 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 518 | E7RAI2 | 282 | SHO1_PICAD High osmolarity signaling protein ... | 43 | 0.43 | 36.2 | 37 | 63 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 519 | Q9UPX8 | 1470 | SHAN2_HUMAN SH3 and multiple ankyrin repeat d... | 54 | 0.47 | 37 | 33 | 52 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0060170; C:cilium membrane; ISS:BHF-UCL.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; ISS:BHF-UCL. | | | | | | | | | | GO:0030160; F:GKAP/Homer scaffold activity; NAS:UniProtKB.::GO:0035255; F:ionotropic glutamate receptor binding; ISS:BHF-UCL.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; NAS:UniProtKB. | 520 | Q5R5W0 | 261 | LASP1_PONAB LIM and SH3 domain protein 1 OS=P... | 73 | 0.47 | 36.2 | 32 | 52 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006811; P:ion transport; IEA:UniProtKB-KW. | 521 | Q14847 | 261 | LASP1_HUMAN LIM and SH3 domain protein 1 OS=H... | 73 | 0.47 | 36.2 | 32 | 52 | GO:0030864; C:cortical actin cytoskeleton; ISS:UniProtKB. | | | | | | | | | | GO:0015075; F:ion transmembrane transporter activity; ISS:UniProtKB.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 522 | Q80Z38 | 1476 | SHAN2_MOUSE SH3 and multiple ankyrin repeat d... | 54 | 0.49 | 37 | 33 | 52 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030426; C:growth cone; IEA:UniProtKB-SubCell.::GO:0001917; C:photoreceptor inner segment; IDA:BHF-UCL.::GO:0001750; C:photoreceptor outer segment; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; IDA:BHF-UCL.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IDA:BHF-UCL. | | | | | | | | | | GO:0035255; F:ionotropic glutamate receptor binding; IPI:BHF-UCL.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | | 523 | Q9R144 | 448 | ANM2_MOUSE Protein arginine N-methyltransfera... | 51 | 0.52 | 36.2 | 33 | 55 | GO:0005829; C:cytosol; ISS:BHF-UCL.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0050681; F:androgen receptor binding; ISS:BHF-UCL.::GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0030331; F:estrogen receptor binding; ISS:UniProtKB.::GO:0008469; F:histone-arginine N-methyltransferase activity; IDA:UniProtKB.::GO:0042975; F:peroxisome proliferator activated receptor binding; ISS:BHF-UCL.::GO:0033142; F:progesterone receptor binding; ISS:BHF-UCL.::GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.::GO:0042974; F:retinoic acid receptor binding; ISS:BHF-UCL.::GO:0046966; F:thyroid hormone receptor binding; ISS:BHF-UCL. | | | | | | | | | | GO:0048588; P:developmental cell growth; IMP:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0033210; P:leptin-mediated signaling pathway; NAS:BHF-UCL.::GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IMP:UniProtKB.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; ISS:UniProtKB.::GO:0042516; P:regulation of tyrosine phosphorylation of Stat3 protein; NAS:BHF-UCL.::GO:0001666; P:response to hypoxia; IDA:BHF-UCL. | 524 | Q61792 | 263 | LASP1_MOUSE LIM and SH3 domain protein 1 OS=M... | 73 | 0.55 | 35.8 | 32 | 52 | GO:0030864; C:cortical actin cytoskeleton; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IDA:MGI. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:MGI.::GO:0015075; F:ion transmembrane transporter activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 525 | Q5U3Q6 | 542 | CIP4_DANRE Cdc42-interacting protein 4 homolo... | 58 | 0.62 | 36.2 | 31 | 55 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 526 | Q99MZ8 | 263 | LASP1_RAT LIM and SH3 domain protein 1 OS=Rat... | 73 | 0.64 | 35.8 | 32 | 52 | GO:0030864; C:cortical actin cytoskeleton; IDA:UniProtKB. | | | | | | | | | | GO:0015075; F:ion transmembrane transporter activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 527 | Q9JK48 | 365 | SHLB1_MOUSE Endophilin-B1 OS=Mus musculus (Mo... | 61 | 0.65 | 35.8 | 30 | 49 | GO:0005783; C:endoplasmic reticulum; IC:MGI.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:MGI.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0043234; C:protein complex; IDA:MGI. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005504; F:fatty acid binding; IDA:MGI.::GO:0042171; F:lysophosphatidic acid acyltransferase activity; IDA:MGI.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0051084; P:'de novo' posttranslational protein folding; IDA:MGI.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0006654; P:phosphatidic acid biosynthetic process; IDA:MGI.::GO:0001844; P:protein insertion into mitochondrial membrane involved in induction of apoptosis; IMP:MGI.::GO:0007165; P:signal transduction; IEA:InterPro. | 528 | Q9JJS5 | 961 | SH3B4_RAT SH3 domain-binding protein 4 OS=Rat... | 89 | 0.66 | 36.2 | 27 | 44 | GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 529 | Q64434 | 451 | PTK6_MOUSE Protein-tyrosine kinase 6 OS=Mus m... | 59 | 0.68 | 35.8 | 31 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MGI. | | | | | | | | | | GO:0060575; P:intestinal epithelial cell differentiation; IMP:UniProtKB.::GO:0045926; P:negative regulation of growth; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0042503; P:tyrosine phosphorylation of Stat3 protein; ISS:UniProtKB.::GO:0042506; P:tyrosine phosphorylation of Stat5 protein; ISS:UniProtKB. | 530 | Q3B7M5 | 260 | LASP1_BOVIN LIM and SH3 domain protein 1 OS=B... | 73 | 0.69 | 35.4 | 32 | 52 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006811; P:ion transport; IEA:UniProtKB-KW. | 531 | Q921I6 | 962 | SH3B4_MOUSE SH3 domain-binding protein 4 OS=M... | 89 | 0.69 | 36.2 | 27 | 44 | GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 532 | Q17QN6 | 466 | EM55_BOVIN 55 kDa erythrocyte membrane protei... | 28 | 0.7 | 35.8 | 57 | 64 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0090022; P:regulation of neutrophil chemotaxis; ISS:UniProtKB. | 533 | Q6FTC4 | 353 | SHO1_CANGA High osmolarity signaling protein ... | 56 | 0.77 | 35.8 | 30 | 61 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 534 | Q7SGL6 | 304 | SHO1_NEUCR High osmolarity signaling protein ... | 100 | 0.8 | 35.4 | 30 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 535 | Q1LWE6 | 516 | BI2L2_DANRE Brain-specific angiogenesis inhib... | 40 | 0.8 | 35.8 | 45 | 65 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 536 | Q4VAA7 | 574 | SNX33_MOUSE Sorting nexin-33 OS=Mus musculus ... | 57 | 0.8 | 35.8 | 33 | 56 | | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 537 | Q5ZJ81 | 403 | SHLB2_CHICK Endophilin-B2 OS=Gallus gallus (C... | 62 | 0.86 | 35.4 | 27 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 538 | Q1DLP2 | 1251 | MYO1_COCIM Myosin-1 OS=Coccidioides immitis (... | 55 | 0.87 | 35.8 | 35 | 49 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 539 | A2R5J1 | 1270 | MYO1_ASPNC Myosin-1 OS=Aspergillus niger (str... | 57 | 0.9 | 35.8 | 33 | 47 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 540 | Q1LYG0 | 1119 | SPD2A_DANRE SH3 and PX domain-containing prot... | 54 | 0.9 | 35.8 | 30 | 59 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0002102; C:podosome; ISS:UniProtKB. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0006801; P:superoxide metabolic process; ISS:UniProtKB. | 541 | Q6CVE9 | 1260 | MYO1_KLULA Myosin-1 OS=1267 / NRRL Y-1140 / W... | 57 | 0.93 | 35.8 | 40 | 53 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | |