rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
271 | Q6TXD4 | 1580 | DNMBP_MOUSE Dynamin-binding protein OS=Mus mu... | 53 | 5.6 | 33.5 | 36 | 53 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 272 | P08032 | 2415 | SPTA1_MOUSE Spectrin alpha chain, erythrocyte... | 85 | 0.0007 | 45.8 | 28 | 44 | GO:0032437; C:cuticular plate; IDA:MGI.::GO:0016020; C:membrane; IDA:MGI.::GO:0008091; C:spectrin; IMP:MGI.::GO:0014731; C:spectrin-associated cytoskeleton; IMP:MGI. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0046982; F:protein heterodimerization activity; IPI:MGI. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IMP:MGI.::GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.::GO:0030097; P:hemopoiesis; IMP:MGI.::GO:0002260; P:lymphocyte homeostasis; IMP:MGI.::GO:0007009; P:plasma membrane organization; IMP:MGI.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IMP:MGI.::GO:0042102; P:positive regulation of T cell proliferation; IMP:MGI.::GO:0008360; P:regulation of cell shape; IMP:MGI. | 273 | Q6XJU9 | 214 | OSTF1_MONAL Osteoclast-stimulating factor 1 O... | 50 | 0.0007 | 44.3 | 40 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 274 | Q7SIG6 | 958 | ASAP2_MOUSE Arf-GAP with SH3 domain, ANK repe... | 65 | 0.0008 | 45.8 | 35 | 57 | GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 275 | Q3UTH8 | 516 | ARHG9_MOUSE Rho guanine nucleotide exchange f... | 54 | 0.0008 | 45.4 | 39 | 61 | GO:0005938; C:cell cortex; TAS:MGI. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:MGI. | 276 | Q58DL7 | 561 | ARHG9_BOVIN Rho guanine nucleotide exchange f... | 54 | 0.0008 | 45.4 | 39 | 61 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 277 | Q09746 | 642 | BZZ1_SCHPO Protein BZZ1 OS=Schizosaccharomyce... | 50 | 0.01 | 42 | 38 | 62 | GO:0030479; C:actin cortical patch; ISS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007015; P:actin filament organization; ISS:PomBase.::GO:0006897; P:endocytosis; ISS:PomBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 278 | O43307 | 516 | ARHG9_HUMAN Rho guanine nucleotide exchange f... | 54 | 0.0009 | 45.4 | 39 | 61 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0034220; P:ion transmembrane transport; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome. | 279 | Q91Z67 | 1071 | FNBP2_MOUSE SLIT-ROBO Rho GTPase-activating p... | 53 | 0.0009 | 45.4 | 32 | 62 | GO:0005743; C:mitochondrial inner membrane; IDA:MGI. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 280 | Q80XI6 | 850 | M3K11_MOUSE Mitogen-activated protein kinase ... | 102 | 0.0009 | 45.4 | 35 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 281 | Q86WV1 | 359 | SKAP1_HUMAN Src kinase-associated phosphoprot... | 49 | 0.001 | 45.1 | 37 | 57 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0003823; F:antigen binding; IPI:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0042169; F:SH2 domain binding; IDA:UniProtKB.::GO:0005070; F:SH3/SH2 adaptor activity; IC:UniProtKB. | | | | | | | | | | GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IMP:UniProtKB. | 282 | O75044 | 1071 | FNBP2_HUMAN SLIT-ROBO Rho GTPase-activating p... | 53 | 0.001 | 45.4 | 32 | 62 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 283 | Q5TCX8 | 1036 | M3KL4_HUMAN Mitogen-activated protein kinase ... | 53 | 0.001 | 45.4 | 38 | 55 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB. | 284 | Q3UND0 | 358 | SKAP2_MOUSE Src kinase-associated phosphoprot... | 83 | 0.001 | 44.7 | 31 | 48 | GO:0005737; C:cytoplasm; IDA:MGI. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI. | 285 | Q32LP7 | 358 | SKAP2_BOVIN Src kinase-associated phosphoprot... | 49 | 0.001 | 44.7 | 41 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW. | 286 | P27447 | 544 | YES_XIPHE Tyrosine-protein kinase Yes OS=Xiph... | 53 | 0.001 | 45.1 | 45 | 60 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 287 | Q3USJ8 | 740 | FCSD2_MOUSE FCH and double SH3 domains protei... | 52 | 0.001 | 45.1 | 40 | 62 | | | | | | | | | | | | | | | | | | | | | | 288 | Q3UUV5 | 355 | SKAP1_MOUSE Src kinase-associated phosphoprot... | 49 | 0.001 | 44.7 | 37 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 289 | Q91Z69 | 1062 | SRGP1_MOUSE SLIT-ROBO Rho GTPase-activating p... | 66 | 0.001 | 45.1 | 32 | 53 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; IDA:MGI.::GO:0017048; F:Rho GTPase binding; IDA:MGI. | | | | | | | | | | GO:0016477; P:cell migration; IDA:MGI.::GO:0007266; P:Rho protein signal transduction; IDA:MGI. | 290 | P0CP00 | 1274 | MYO1_CRYNJ Myosin-1 OS=ATCC MYA-565) (Filobas... | 53 | 0.001 | 45.1 | 42 | 64 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 291 | P0CP01 | 1274 | MYO1_CRYNB Myosin-1 OS=(Filobasidiella neofor... | 53 | 0.001 | 45.1 | 42 | 64 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 292 | Q80U40 | 1072 | RIMB2_MOUSE RIMS-binding protein 2 OS=Mus mus... | 68 | 0.001 | 45.1 | 34 | 60 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 293 | Q9ES28 | 862 | ARHG7_MOUSE Rho guanine nucleotide exchange f... | 50 | 0.001 | 45.1 | 42 | 56 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 294 | Q4V7G1 | 354 | SKAP1_RAT Src kinase-associated phosphoprotei... | 49 | 0.001 | 44.3 | 37 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0042169; F:SH2 domain binding; IPI:RGD. | | | | | | | | | | | 295 | Q16584 | 847 | M3K11_HUMAN Mitogen-activated protein kinase ... | 66 | 0.001 | 44.7 | 33 | 55 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005874; C:microtubule; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004706; F:JUN kinase kinase kinase activity; ISS:UniProtKB.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; IMP:UniProtKB.::GO:0008283; P:cell proliferation; IMP:UniProtKB.::GO:0000080; P:G1 phase of mitotic cell cycle; IMP:UniProtKB.::GO:0007017; P:microtubule-based process; IMP:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB. | 296 | Q812A2 | 1099 | SRGP3_MOUSE SLIT-ROBO Rho GTPase-activating p... | 66 | 0.002 | 44.7 | 32 | 52 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 297 | O55043 | 646 | ARHG7_RAT Rho guanine nucleotide exchange fac... | 50 | 0.002 | 44.7 | 42 | 56 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:RGD.::GO:0030426; C:growth cone; IDA:RGD.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0043615; P:astrocyte cell migration; IMP:RGD.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IDA:RGD. | 298 | Q7Z6B7 | 1085 | SRGP1_HUMAN SLIT-ROBO Rho GTPase-activating p... | 66 | 0.002 | 44.7 | 32 | 53 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome. | 299 | Q8VDG6 | 1002 | M3KL4_MOUSE Mitogen-activated protein kinase ... | 78 | 0.002 | 44.7 | 33 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 300 | O60861 | 476 | GAS7_HUMAN Growth arrest-specific protein 7 O... | 54 | 0.002 | 44.3 | 44 | 63 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc. | | | | | | | | | | GO:0007050; P:cell cycle arrest; TAS:ProtInc. | 301 | Q6DII7 | 345 | SKAP1_XENTR Src kinase-associated phosphoprot... | 51 | 0.002 | 43.9 | 37 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | |