rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
211 | Q5ZJJ9 | 202 | OSTF1_CHICK Osteoclast-stimulating factor 1 O... | 50 | 0.00005 | 47.8 | 44 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 212 | Q96HU1 | 749 | SGSM3_HUMAN Small G protein signaling modulat... | 56 | 0.00005 | 49.3 | 41 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0017137; F:Rab GTPase binding; IDA:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0032486; P:Rap protein signal transduction; IEP:UniProtKB. | 213 | Q9BY11 | 444 | PACN1_HUMAN Protein kinase C and casein kinas... | 54 | 0.00005 | 49.3 | 44 | 67 | | | | | | | | | | | GO:0004672; F:protein kinase activity; NAS:UniProtKB. | | | | | | | | | | GO:0006897; P:endocytosis; NAS:UniProtKB. | 214 | Q62422 | 215 | OSTF1_MOUSE Osteoclast-stimulating factor 1 O... | 50 | 0.00005 | 47.8 | 44 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017124; F:SH3 domain binding; IDA:MGI. | | | | | | | | | | | 215 | Q7T2V3 | 1005 | M3K10_XENLA Mitogen-activated protein kinase ... | 60 | 0.00005 | 49.7 | 35 | 58 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004706; F:JUN kinase kinase kinase activity; IDA:UniProtKB.::GO:0019900; F:kinase binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0048365; F:Rac GTPase binding; IDA:UniProtKB.::GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:UniProtKB. | | | | | | | | | | GO:0071570; P:cement gland development; IMP:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; IDA:UniProtKB.::GO:0048793; P:pronephros development; IMP:UniProtKB. | 216 | P97369 | 339 | NCF4_MOUSE Neutrophil cytosol factor 4 OS=Mus... | 60 | 0.00005 | 48.5 | 38 | 58 | GO:0005737; C:cytoplasm; IDA:MGI. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 217 | Q62415 | 1087 | ASPP1_MOUSE Apoptosis-stimulating of p53 prot... | 53 | 0.00007 | 49.3 | 40 | 62 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB. | 218 | P16086 | 2472 | SPTA2_RAT Spectrin alpha chain, brain OS=Ratt... | 151 | 0.00007 | 49.3 | 26 | 43 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0008091; C:spectrin; TAS:RGD. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0032403; F:protein complex binding; IPI:RGD.::GO:0047485; F:protein N-terminus binding; IPI:RGD.::GO:0019905; F:syntaxin binding; IPI:RGD. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; IMP:RGD.::GO:0051693; P:actin filament capping; IEA:UniProtKB-KW. | 219 | P20929 | 6669 | NEBU_HUMAN Nebulin OS=Homo sapiens (Human). G... | 89 | 0.00007 | 49.3 | 30 | 53 | GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030018; C:Z disc; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0008307; F:structural constituent of muscle; TAS:ProtInc. | | | | | | | | | | GO:0030049; P:muscle filament sliding; TAS:Reactome.::GO:0007517; P:muscle organ development; TAS:ProtInc.::GO:0030832; P:regulation of actin filament length; NAS:UniProtKB.::GO:0007525; P:somatic muscle development; NAS:UniProtKB. | 220 | P16546 | 2472 | SPTA2_MOUSE Spectrin alpha chain, brain OS=Mu... | 151 | 0.00008 | 49.3 | 26 | 43 | GO:0032437; C:cuticular plate; IDA:MGI.::GO:0005916; C:fascia adherens; IDA:MGI.::GO:0016328; C:lateral plasma membrane; IDA:MGI.::GO:0033270; C:paranode region of axon; IDA:BHF-UCL.::GO:0030018; C:Z disc; IDA:MGI. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IDA:MGI.::GO:0030507; F:spectrin binding; IDA:MGI. | | | | | | | | | | GO:0051693; P:actin filament capping; IEA:UniProtKB-KW. | 221 | Q8MJ49 | 214 | OSTF1_PIG Osteoclast-stimulating factor 1 OS=... | 50 | 0.00008 | 47.4 | 44 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 222 | Q8IZP0 | 508 | ABI1_HUMAN Abl interactor 1 OS=Homo sapiens (... | 63 | 0.00008 | 48.5 | 35 | 59 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:ProtInc.::GO:0005783; C:endoplasmic reticulum; TAS:ProtInc.::GO:0030175; C:filopodium; IDA:UniProtKB.::GO:0030426; C:growth cone; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; TAS:ProtInc.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; TAS:ProtInc. | | | | | | | | | | GO:0008154; P:actin polymerization or depolymerization; NAS:UniProtKB.::GO:0006928; P:cellular component movement; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc. | 223 | Q92882 | 214 | OSTF1_HUMAN Osteoclast-stimulating factor 1 O... | 50 | 0.00008 | 47.4 | 44 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0001503; P:ossification; TAS:ProtInc.::GO:0007165; P:signal transduction; TAS:ProtInc. | 224 | A6H8I2 | 753 | SGSM3_XENLA Small G protein signaling modulat... | 56 | 0.00009 | 48.5 | 39 | 59 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005097; F:Rab GTPase activator activity; IEA:InterPro. | | | | | | | | | | | 225 | O77775 | 527 | NCF2_BOVIN Neutrophil cytosol factor 2 OS=Bos... | 53 | 0.022 | 40.8 | 34 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | | 226 | B0CRJ3 | 1252 | MYO1_LACBS Myosin-1 OS=deceiver) (Laccaria la... | 53 | 0.0001 | 48.5 | 42 | 68 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 227 | O74653 | 871 | POB1_SCHPO Protein pob1 OS=Schizosaccharomyce... | 57 | 0.0001 | 48.1 | 40 | 60 | GO:0051285; C:cell cortex of cell tip; IDA:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0000920; P:cytokinetic cell separation; IMP:PomBase.::GO:0008360; P:regulation of cell shape; IMP:PomBase. | 228 | Q09822 | 927 | CDC15_SCHPO Cell division control protein 15 ... | 60 | 0.0002 | 48.1 | 33 | 60 | GO:0051286; C:cell tip; IDA:PomBase.::GO:0005737; C:cytoplasm; IDA:PomBase.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0032178; C:medial membrane band; IDA:PomBase. | | | | | | | | | | GO:0043495; F:protein anchor; TAS:PomBase. | | | | | | | | | | GO:0030866; P:cortical actin cytoskeleton organization; IMP:PomBase.::GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; IMP:PomBase.::GO:0061166; P:establishment of endoplasmic reticulum localization involved in endoplasmic reticulum polarization at cell division site; IMP:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051125; P:regulation of actin nucleation; IGI:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase. | 229 | P35991 | 659 | BTK_MOUSE Tyrosine-protein kinase BTK OS=Mus ... | 64 | 0.0002 | 47.8 | 42 | 58 | GO:0031410; C:cytoplasmic vesicle; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0048469; P:cell maturation; IMP:MGI.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; IMP:MGI.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 230 | P46108 | 304 | CRK_HUMAN Adapter molecule crk OS=Homo sapien... | 52 | 0.0002 | 47 | 42 | 58 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005768; C:endosome; TAS:Reactome.::GO:0005634; C:nucleus; TAS:ProtInc.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB. | | | | | | | | | | GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0048013; P:ephrin receptor signaling pathway; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0032956; P:regulation of actin cytoskeleton organization; IDA:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; IDA:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc. | 231 | Q64010 | 304 | CRK_MOUSE Adapter molecule crk OS=Mus musculu... | 52 | 0.0002 | 47 | 42 | 58 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0045309; F:protein phosphorylated amino acid binding; IDA:MGI.::GO:0005070; F:SH3/SH2 adaptor activity; IPI:BHF-UCL. | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 232 | Q63768 | 304 | CRK_RAT Adapter molecule crk OS=Rattus norveg... | 52 | 0.0002 | 47 | 42 | 58 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; TAS:RGD.::GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0051270; P:regulation of cellular component movement; TAS:RGD.::GO:0035020; P:regulation of Rac protein signal transduction; IMP:RGD.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 233 | P42522 | 1182 | MYOC_DICDI Myosin IC heavy chain OS=Dictyoste... | 56 | 0.0002 | 47.8 | 36 | 63 | GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0097203; C:phagocytic cup lip; IDA:dictyBase. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006909; P:phagocytosis; IMP:dictyBase. | 234 | A3LXQ8 | 475 | HSE1_PICST Class E vacuolar protein-sorting m... | 54 | 0.0002 | 47.4 | 41 | 56 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 235 | Q6XZF7 | 1577 | DNMBP_HUMAN Dynamin-binding protein OS=Homo s... | 53 | 5.9 | 33.1 | 34 | 53 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 236 | Q7ZYG4 | 214 | OSTF1_XENLA Osteoclast-stimulating factor 1 O... | 50 | 0.0002 | 46.2 | 40 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 237 | P43069 | 1333 | CDC25_CANAL Cell division control protein 25 ... | 57 | 0.0002 | 47.8 | 44 | 53 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; IDA:CGD. | | | | | | | | | | GO:0019933; P:cAMP-mediated signaling; IMP:CGD.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0071333; P:cellular response to glucose stimulus; IMP:CGD.::GO:0030447; P:filamentous growth; IMP:CGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007265; P:Ras protein signal transduction; IGI:CGD.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro. | 238 | Q1KKW7 | 363 | SKAP1_TAKRU Src kinase-associated phosphoprot... | 50 | 0.0002 | 47 | 36 | 62 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 239 | P19878 | 526 | NCF2_HUMAN Neutrophil cytosol factor 2 OS=Hom... | 117 | 0.008 | 42.4 | 26 | 47 | GO:0043020; C:NADPH oxidase complex; TAS:BHF-UCL.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0032010; C:phagolysosome; TAS:Reactome. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB. | | | | | | | | | | GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006968; P:cellular defense response; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:BHF-UCL.::GO:0045730; P:respiratory burst; TAS:BHF-UCL.::GO:0042554; P:superoxide anion generation; TAS:BHF-UCL. | 240 | O94868 | 740 | FCSD2_HUMAN FCH and double SH3 domains protei... | 52 | 0.0002 | 47.4 | 42 | 62 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 241 | A7E3N2 | 527 | NCF2_RAT Neutrophil cytosol factor 2 OS=Rattu... | 53 | 0.039 | 40 | 34 | 57 | GO:0005624; C:membrane fraction; IDA:RGD. | | | | | | | | | | | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0032870; P:cellular response to hormone stimulus; IDA:RGD.::GO:0045777; P:positive regulation of blood pressure; IMP:RGD.::GO:0043525; P:positive regulation of neuron apoptotic process; IMP:RGD.::GO:0014823; P:response to activity; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IDA:RGD.::GO:0055093; P:response to hyperoxia; IEP:RGD.::GO:0034616; P:response to laminar fluid shear stress; IEP:RGD.::GO:0033993; P:response to lipid; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IDA:RGD.::GO:0014070; P:response to organic cyclic compound; IDA:RGD.::GO:0032570; P:response to progesterone stimulus; IEP:RGD. |