UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YFR024C-A

Length:

459

Number of sequences:

5887

Description:

YFR024C-A LSB3 SGDID:S000002968, Chr VI from 203292-201960,203433-203387, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein containing a C-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P43603	459	LSB3_YEAST LAS seventeen-binding protein 3 OS...	459	0	916	100	100	GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.
									GO:0005515; F:protein binding; IPI:IntAct.
									GO:0051666; P:actin cortical patch localization; IMP:SGD.
2	A7A261	459	LSB3_YEAS7 LAS seventeen-binding protein 3 OS...	459	0	916	100	100	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
3	P32793	468	YSC84_YEAST Protein YSC84 OS=Saccharomyces ce...	510	4e-176	509	63	71	GO:0030479; C:actin cortical patch; IDA:SGD.
									GO:0051015; F:actin filament binding; IDA:SGD.
									GO:0051666; P:actin cortical patch localization; IMP:SGD.::GO:0051017; P:actin filament bundle assembly; IDA:SGD.::GO:0006897; P:endocytosis; IGI:SGD.
4	Q9URW6	430	YIE2_SCHPO SH3 domain-containing protein PJ69...	468	3e-120	365	46	60	GO:0030479; C:actin cortical patch; ISS:PomBase.
									GO:0007015; P:actin filament organization; ISS:PomBase.::GO:0006897; P:endocytosis; ISS:PomBase.
5	Q3SZ01	341	SH3Y1_BOVIN SH3 domain-containing YSC84-like ...	55	0.00000000000008	75.9	56	75
6	Q96HL8	342	SH3Y1_HUMAN SH3 domain-containing YSC84-like ...	55	0.0000000000003	74.3	55	75
7	Q5RAQ2	342	SH3Y1_PONAB SH3 domain-containing YSC84-like ...	55	0.0000000000003	74.3	55	75
8	B0BNA1	340	SH3Y1_RAT SH3 domain-containing YSC84-like pr...	61	0.000000000001	72.8	54	70
9	O08641	340	SH3Y1_MOUSE SH3 domain-containing YSC84-like ...	55	0.000000000002	71.6	53	73
									GO:0005515; F:protein binding; IPI:IntAct.
10	Q6DFH5	335	SH3Y1_XENLA SH3 domain-containing YSC84-like ...	73	0.000000000000006	79.3	52	63
11	O74352	466	HOB1_SCHPO Protein hob1 OS=Schizosaccharomyce...	54	0.000000000002	72.8	52	74	GO:0051285; C:cell cortex of cell tip; TAS:PomBase.::GO:0031097; C:medial cortex; TAS:PomBase.
									GO:0051020; F:GTPase binding; NAS:PomBase.
									GO:0030702; P:chromatin silencing at centromere; IMP:PomBase.::GO:0006348; P:chromatin silencing at telomere; IMP:PomBase.::GO:0007163; P:establishment or maintenance of cell polarity; IGI:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0006974; P:response to DNA damage stimulus; IGI:PomBase.::GO:0000723; P:telomere maintenance; IMP:PomBase.
12	O43125	296	CSH3_SCHPO Protein csh3 OS=Schizosaccharomyce...	56	0.000000000005	70.1	50	73	GO:0005737; C:cytoplasm; IDA:PomBase.
									GO:0030036; P:actin cytoskeleton organization; ISS:PomBase.
13	Q15811	1721	ITSN1_HUMAN Intersectin-1 OS=Homo sapiens (Hu...	61	5.2	33.5	36	49	GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005905; C:coated pit; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
									GO:0005509; F:calcium ion binding; NAS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0070064; F:proline-rich region binding; IPI:UniProtKB.::GO:0032947; F:protein complex scaffold; IDA:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
									GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0048488; P:synaptic vesicle endocytosis; TAS:ProtInc.
14	P39743	482	RV167_YEAST Reduced viability upon starvation...	54	0.00000000005	68.2	48	70	GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.
									GO:0003779; F:actin binding; IEA:UniProtKB-KW.
									GO:0051666; P:actin cortical patch localization; IMP:SGD.::GO:0006897; P:endocytosis; IMP:SGD.::GO:0060988; P:lipid tube assembly; IDA:SGD.
15	Q6YKA8	211	DRK_DROSI Protein E(sev)2B OS=Drosophila simu...	55	0.00006	47.8	35	62	GO:0005886; C:plasma membrane; ISS:UniProtKB.
									GO:0005070; F:SH3/SH2 adaptor activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
16	Q08012	211	DRK_DROME Protein enhancer of sevenless 2B OS...	55	0.00006	47.8	35	62	GO:0005886; C:plasma membrane; IDA:UniProtKB.
									GO:0005118; F:sevenless binding; IPI:FlyBase.::GO:0005070; F:SH3/SH2 adaptor activity; NAS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
									GO:0007015; P:actin filament organization; IMP:FlyBase.::GO:0007256; P:activation of JNKK activity; NAS:UniProtKB.::GO:0008595; P:anterior/posterior axis specification, embryo; TAS:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IGI:FlyBase.::GO:0008355; P:olfactory learning; IMP:FlyBase.::GO:0045678; P:positive regulation of R7 cell differentiation; IGI:FlyBase.::GO:0007265; P:Ras protein signal transduction; IPI:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0045500; P:sevenless signaling pathway; IGI:FlyBase.::GO:0007614; P:short-term memory; IMP:FlyBase.::GO:0008293; P:torso signaling pathway; TAS:FlyBase.
17	P29355	228	SEM5_CAEEL Sex muscle abnormal protein 5 OS=C...	55	0.024	40	31	56
									GO:0016477; P:cell migration; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0019915; P:lipid storage; IMP:WormBase.::GO:0030539; P:male genitalia development; IMP:WormBase.::GO:0007517; P:muscle organ development; IMP:WormBase.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0031344; P:regulation of cell projection organization; IMP:WormBase.::GO:0040028; P:regulation of vulval development; IMP:WormBase.::GO:0032940; P:secretion by cell; IMP:WormBase.
18	O74749	373	HSE1_SCHPO Class E vacuolar protein-sorting m...	64	0.0000000003	65.5	45	61	GO:0005829; C:cytosol; IDA:PomBase.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0033565; C:ESCRT-0 complex; IPI:PomBase.::GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
									GO:0031321; P:ascospore-type prospore assembly; IGI:PomBase.::GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006900; P:membrane budding; IC:PomBase.::GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:PomBase.
19	Q9Z0R4	1714	ITSN1_MOUSE Intersectin-1 OS=Mus musculus (Mo...	81	3.1	34.3	32	46	GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0030139; C:endocytic vesicle; IDA:MGI.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
									GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0019209; F:kinase activator activity; IDA:MGI.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
									GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:MGI.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IDA:MGI.
20	Q5BBL4	581	HSE1_EMENI Class E vacuolar protein-sorting m...	122	0.0000000005	65.5	35	48	GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.
21	Q99469	402	STAC_HUMAN SH3 and cysteine-rich domain-conta...	52	0.0000000005	64.7	52	69	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; TAS:ProtInc.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0035556; P:intracellular signal transduction; IEA:InterPro.
22	A0JNJ1	403	STAC_BOVIN SH3 and cysteine-rich domain-conta...	54	0.0000000005	64.7	52	69	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0035556; P:intracellular signal transduction; IEA:InterPro.
23	O42287	1270	ITSN1_XENLA Intersectin-1 OS=Xenopus laevis (...	60	2.3	34.7	35	47	GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
24	Q2GT05	713	HSE1_CHAGB Class E vacuolar protein-sorting m...	149	0.0000000006	65.1	28	43	GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.
25	P97306	403	STAC_MOUSE SH3 and cysteine-rich domain-conta...	54	0.0000000006	64.3	52	69	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0034605; P:cellular response to heat; IDA:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.
26	Q6NRD3	826	SH3R1_XENLA E3 ubiquitin-protein ligase SH3RF...	56	1.1	35.4	29	54	GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
27	Q7S6J4	745	HSE1_NEUCR Class E vacuolar protein-sorting m...	51	0.0000000007	64.7	55	67	GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.
28	P10569	1168	MYSC_ACACA Myosin IC heavy chain OS=Acanthamo...	56	0.0000000008	65.1	50	71	GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
29	A2QW93	611	HSE1_ASPNC Class E vacuolar protein-sorting m...	124	0.000000001	63.9	34	45	GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.
30	Q91X43	789	SH319_MOUSE SH3 domain-containing protein 19 ...	57	0.0002	47.8	37	61
									GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB.
31	Q8AXV0	367	SH3G1_CHICK Endophilin-A2 OS=Gallus gallus (C...	69	0.000000002	62.8	39	59	GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
									GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
									GO:0006897; P:endocytosis; IEA:UniProtKB-KW.

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