Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFR021W
Length:
500
Number of sequences:
5887
Description:
YFR021W ATG18 SGDID:S000001917, Chr VI from 194812-196314, Genome Release 64-1-1, Verified ORF, "Phosphoinositide binding protein required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; binds both phosphatidylinositol (3,5)-bisphosphate and phosphatidylinositol 3-phosphate; WD-40 repeat protein"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
241P68040    317   GBLP_MOUSE Guanine nucleotide-binding protein...811.7     34.7     25     49GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; IDA:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0001891; C:phagocytic cup; ISS:UniProtKB.
GO:0008200; F:ion channel inhibitor activity; IDA:UniProtKB.::GO:0005080; F:protein kinase C binding; ISS:UniProtKB.::GO:0030292; F:protein tyrosine kinase inhibitor activity; ISS:UniProtKB.::GO:0030971; F:receptor tyrosine kinase binding; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0050765; P:negative regulation of phagocytosis; ISS:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; ISS:UniProtKB.::GO:0043547; P:positive regulation of GTPase activity; ISS:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0032464; P:positive regulation of protein homooligomerization; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0051726; P:regulation of cell cycle; ISS:UniProtKB.::GO:0051302; P:regulation of cell division; ISS:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.::GO:0032880; P:regulation of protein localization; ISS:UniProtKB.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.
242Q4R7Y4    317   GBLP_MACFA Guanine nucleotide-binding protein...811.7     34.7     25     49GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0001891; C:phagocytic cup; ISS:UniProtKB.
GO:0005080; F:protein kinase C binding; ISS:UniProtKB.::GO:0030292; F:protein tyrosine kinase inhibitor activity; ISS:UniProtKB.::GO:0030971; F:receptor tyrosine kinase binding; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0050765; P:negative regulation of phagocytosis; ISS:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; ISS:UniProtKB.::GO:0043547; P:positive regulation of GTPase activity; ISS:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0032464; P:positive regulation of protein homooligomerization; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0051726; P:regulation of cell cycle; ISS:UniProtKB.::GO:0051302; P:regulation of cell division; ISS:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.::GO:0032880; P:regulation of protein localization; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.
243P63244    317   GBLP_HUMAN Guanine nucleotide-binding protein...811.7     34.7     25     49GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0001891; C:phagocytic cup; IDA:UniProtKB.::GO:0015935; C:small ribosomal subunit; ISS:UniProtKB.
GO:0008200; F:ion channel inhibitor activity; ISS:UniProtKB.::GO:0005080; F:protein kinase C binding; IDA:UniProtKB.::GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.::GO:0030292; F:protein tyrosine kinase inhibitor activity; IDA:UniProtKB.::GO:0030971; F:receptor tyrosine kinase binding; IDA:UniProtKB.::GO:0042169; F:SH2 domain binding; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.::GO:0050765; P:negative regulation of phagocytosis; IMP:UniProtKB.::GO:0017148; P:negative regulation of translation; ISS:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; ISS:UniProtKB.::GO:0043547; P:positive regulation of GTPase activity; IDA:UniProtKB.::GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0032464; P:positive regulation of protein homooligomerization; IDA:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; IDA:UniProtKB.::GO:0051726; P:regulation of cell cycle; IDA:UniProtKB.::GO:0051302; P:regulation of cell division; ISS:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.::GO:0032880; P:regulation of protein localization; ISS:UniProtKB.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.
244P63247    317   GBLP_CHICK Guanine nucleotide-binding protein...811.7     34.7     25     49GO:0043025; C:neuronal cell body; ISS:UniProtKB.
GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; ISS:UniProtKB.::GO:0051302; P:regulation of cell division; ISS:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.::GO:0032880; P:regulation of protein localization; ISS:UniProtKB.::GO:0007165; P:signal transduction; TAS:UniProtKB.
245P63243    317   GBLP_BOVIN Guanine nucleotide-binding protein...811.7     34.7     25     49GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0001891; C:phagocytic cup; ISS:UniProtKB.
GO:0005080; F:protein kinase C binding; ISS:UniProtKB.::GO:0030292; F:protein tyrosine kinase inhibitor activity; ISS:UniProtKB.::GO:0030971; F:receptor tyrosine kinase binding; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0050765; P:negative regulation of phagocytosis; ISS:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; ISS:UniProtKB.::GO:0043547; P:positive regulation of GTPase activity; ISS:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0032464; P:positive regulation of protein homooligomerization; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0051726; P:regulation of cell cycle; ISS:UniProtKB.::GO:0051302; P:regulation of cell division; ISS:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.::GO:0032880; P:regulation of protein localization; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.
246O74309    807   SLM9_SCHPO Histone transcription regulator sl...1111.7     35     23     45GO:0005829; C:cytosol; IDA:PomBase.::GO:0000417; C:HIR complex; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0003714; F:transcription corepressor activity; TAS:PomBase.
GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0006995; P:cellular response to nitrogen starvation; IMP:PomBase.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0030702; P:chromatin silencing at centromere; IMP:PomBase.::GO:0030466; P:chromatin silencing at silent mating-type cassette; IMP:PomBase.::GO:0006336; P:DNA replication-independent nucleosome assembly; TAS:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.::GO:0007070; P:negative regulation of transcription from RNA polymerase II promoter during mitosis; IMP:PomBase.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IMP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
247P38123    315   SWD3_YEAST COMPASS component SWD3 OS=Saccharo...841.8     34.7     27     50GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0006348; P:chromatin silencing at telomere; IMP:SGD.::GO:0051568; P:histone H3-K4 methylation; IDA:SGD.::GO:0000723; P:telomere maintenance; IMP:SGD.
248P27612    794   PLAP_MOUSE Phospholipase A-2-activating prote...1501.8     35     22     49
GO:0016005; F:phospholipase A2 activator activity; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.
GO:0006954; P:inflammatory response; IDA:MGI.
249O42248    317   GBLP_DANRE Guanine nucleotide-binding protein...1051.8     34.7     26     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0001525; P:angiogenesis; IMP:ZFIN.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IMP:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; IMP:UniProtKB.::GO:0051302; P:regulation of cell division; IMP:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; IMP:UniProtKB.::GO:0032880; P:regulation of protein localization; IMP:UniProtKB.
250Q0P593    415   WDR69_BOVIN Outer row dynein assembly protein...951.9     34.7     24     47GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
251O55029    905   COPB2_MOUSE Coatomer subunit beta' OS=Mus mus...1072     35     23     45
GO:0005488; F:binding; IEA:InterPro.::GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
252O35142    905   COPB2_RAT Coatomer subunit beta' OS=Rattus no...1072     35     23     45GO:0030663; C:COPI coated vesicle membrane; IEA:UniProtKB-SubCell.::GO:0030117; C:membrane coat; IEA:InterPro.
GO:0005080; F:protein kinase C binding; IPI:RGD.::GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
253Q4R8E7    415   WDR69_MACFA Outer row dynein assembly protein...962     34.7     27     51GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
254P35606    906   COPB2_HUMAN Coatomer subunit beta' OS=Homo sa...1072     35     23     45GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0030126; C:COPI vesicle coat; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.
GO:0005488; F:binding; IEA:InterPro.::GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0048205; P:COPI coating of Golgi vesicle; TAS:Reactome.::GO:0006891; P:intra-Golgi vesicle-mediated transport; IDA:UniProtKB.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; TAS:UniProtKB.
255Q4R4I8    906   COPB2_MACFA Coatomer subunit beta' OS=Macaca ...1072     35     23     45GO:0030663; C:COPI coated vesicle membrane; IEA:UniProtKB-SubCell.::GO:0030117; C:membrane coat; IEA:InterPro.
GO:0005488; F:binding; IEA:InterPro.::GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
256P35605    906   COPB2_BOVIN Coatomer subunit beta' OS=Bos tau...1072.1     34.7     23     45GO:0030126; C:COPI vesicle coat; IDA:UniProtKB.
GO:0005080; F:protein kinase C binding; ISS:AgBase.::GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0006891; P:intra-Golgi vesicle-mediated transport; TAS:UniProtKB.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; TAS:UniProtKB.
257Q5R664    906   COPB2_PONAB Coatomer subunit beta' OS=Pongo a...1072.1     34.7     23     45GO:0030663; C:COPI coated vesicle membrane; IEA:UniProtKB-SubCell.::GO:0030117; C:membrane coat; IEA:InterPro.
GO:0005488; F:binding; IEA:InterPro.::GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
258P54319    795   PLAP_RAT Phospholipase A-2-activating protein...1502.1     34.7     22     49
259Q1HPW4    329   EIF3I_BOMMO Eukaryotic translation initiation...612.1     34.3     30     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
260P49177    377   GBB_ARATH Guanine nucleotide-binding protein ...1212.2     34.3     29     45GO:0080008; C:CUL4 RING ubiquitin ligase complex; IPI:TAIR.::GO:0005783; C:endoplasmic reticulum; IDA:TAIR.::GO:0005834; C:heterotrimeric G-protein complex; IPI:TAIR.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0009817; P:defense response to fungus, incompatible interaction; IMP:TAIR.::GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:TAIR.::GO:0010154; P:fruit development; IMP:TAIR.::GO:0009867; P:jasmonic acid mediated signaling pathway; IMP:TAIR.::GO:0048527; P:lateral root development; IMP:TAIR.::GO:0009788; P:negative regulation of abscisic acid mediated signaling pathway; IMP:UniProtKB.::GO:0009887; P:organ morphogenesis; IMP:TAIR.::GO:0072593; P:reactive oxygen species metabolic process; IMP:TAIR.::GO:0009723; P:response to ethylene stimulus; IMP:TAIR.::GO:0009845; P:seed germination; IEP:UniProtKB.
261Q40687    380   GBB_ORYSJ Guanine nucleotide-binding protein ...452.2     34.3     36     56
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0007186; P:G-protein coupled receptor signaling pathway; IEP:Gramene.
262Q54MZ3    499   CDC20_DICDI Anaphase-promoting complex subuni...1312.6     34.3     29     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
263Q91WQ5    589   TAF5L_MOUSE TAF5-like RNA polymerase II p300/...1352.8     34.3     23     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
264Q9HCE6    1279   ARGAL_HUMAN Rho guanine nucleotide exchange f...682.8     34.7     35     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
265B6GZD3    464   LIS12_PENCW Nuclear distribution protein nudF...822.8     34.3     27     49GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
266P93398    377   GBB2_TOBAC Guanine nucleotide-binding protein...782.8     33.9     29     49
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
267Q54MP8    2200   Y5837_DICDI Bromodomain and WD repeat-contain...382.9     34.7     37     66
268Q5R5M3    1233   ARGAL_PONAB Rho guanine nucleotide exchange f...683     34.3     35     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
269O14301    595   YE85_SCHPO Uncharacterized WD repeat-containi...613.1     34.3     33     56GO:0030479; C:actin cortical patch; ISS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0030042; P:actin filament depolymerization; ISS:PomBase.
270Q6FPI5    1029   SED4_CANGA Putative guanine nucleotide-exchan...953.1     34.3     27     51GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
271Q01369    316   GBLP_NEUCR Guanine nucleotide-binding protein...1103.2     33.9     28     45
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