Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFR019W
Length:
2278
Number of sequences:
5887
Description:
YFR019W FAB1 SGDID:S000001915, Chr VI from 184502-191338, Genome Release 64-1-1, Verified ORF, "1-phosphatidylinositol-3-phosphate 5-kinase; vacuolar membrane kinase that generates phosphatidylinositol (3,5)P2, which is involved in vacuolar sorting and homeostasis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q80XI4    416   PI42B_MOUSE Phosphatidylinositol 5-phosphate ...1830.000000004     65.1     27     51GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0016309; F:1-phosphatidylinositol-5-phosphate 4-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.
62Q0P5F7    421   PI42C_BOVIN Phosphatidylinositol 5-phosphate ...1950.000000004     65.1     27     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0016309; F:1-phosphatidylinositol-5-phosphate 4-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
63Q6ZPK7    905   LST2_MOUSE Lateral signaling target protein 2...600.000000005     65.9     47     58GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0031901; C:early endosome membrane; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB.
GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; ISS:UniProtKB.
64A0JMD2    969   LST2_DANRE Lateral signaling target protein 2...600.000000005     65.5     45     58GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0031901; C:early endosome membrane; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB.
GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; ISS:UniProtKB.
65O70172    405   PI42A_MOUSE Phosphatidylinositol 5-phosphate ...1830.000000005     64.7     28     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0016309; F:1-phosphatidylinositol-5-phosphate 4-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0035855; P:megakaryocyte development; IMP:UniProtKB.
66B0WAQ0    907   LST2_CULQU Lateral signaling target protein 2...600.000000006     65.5     37     55
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
67Q6VNB8    3508   WDFY3_MOUSE WD repeat and FYVE domain-contain...790.000000006     65.5     37     52
GO:0003831; F:beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; IDA:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
68Q55GN6    719   Y7588_DICDI Probable phosphatidylinositol pho...1950.000000006     65.1     29     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016307; F:phosphatidylinositol phosphate kinase activity; ISS:dictyBase.
69Q8IZQ1    3526   WDFY3_HUMAN WD repeat and FYVE domain-contain...790.000000007     65.5     37     52GO:0044444; C:cytoplasmic part; IDA:MGI.::GO:0019898; C:extrinsic to membrane; IDA:MGI.::GO:0005635; C:nuclear envelope; IDA:MGI.
GO:0005545; F:1-phosphatidylinositol binding; IDA:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
70O24732    545   THSB_THEK8 Thermosome subunit beta OS=Thermoc...1980.000000008     64.3     25     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.
71O28045    545   THSA_ARCFU Thermosome subunit alpha OS=9628 /...1860.000000008     64.3     25     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.
72Q0P4S0    951   LST2_XENTR Lateral signaling target protein 2...600.000000009     64.7     45     57GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0031901; C:early endosome membrane; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB.
GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; ISS:UniProtKB.
73Q6EX42    801   PI5K1_ORYSJ Phosphatidylinositol 4-phosphate ...1770.00000001     64.7     28     49
GO:0016308; F:1-phosphatidylinositol-4-phosphate 5-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009908; P:flower development; IEA:UniProtKB-KW.
74O48709    705   PI5K3_ARATH Phosphatidylinositol 4-phosphate ...1650.00000001     63.9     28     53GO:0016324; C:apical plasma membrane; IDA:TAIR.::GO:0005737; C:cytoplasm; IDA:TAIR.
GO:0016308; F:1-phosphatidylinositol-4-phosphate 5-kinase activity; IDA:TAIR.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0048768; P:root hair cell tip growth; IMP:TAIR.
75P70182    546   PI51A_MOUSE Phosphatidylinositol 4-phosphate ...2030.00000001     63.9     28     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0032587; C:ruffle membrane; IDA:MGI.
GO:0016308; F:1-phosphatidylinositol-4-phosphate 5-kinase activity; IDA:MGI.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.
GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0032863; P:activation of Rac GTPase activity; ISS:UniProtKB.::GO:0060326; P:cell chemotaxis; ISS:UniProtKB.::GO:0010761; P:fibroblast migration; IMP:MGI.::GO:0048041; P:focal adhesion assembly; ISS:UniProtKB.::GO:0072661; P:protein targeting to plasma membrane; ISS:UniProtKB.::GO:0097178; P:ruffle assembly; ISS:UniProtKB.
76Q8TBX8    421   PI42C_HUMAN Phosphatidylinositol 5-phosphate ...1950.00000001     63.2     27     50GO:0005737; C:cytoplasm; IDA:HPA.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.
GO:0016309; F:1-phosphatidylinositol-5-phosphate 4-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0016307; F:phosphatidylinositol phosphate kinase activity; IEA:InterPro.
77Q54TC3    585   SLOB1_DICDI Probable inactive serine/threonin...800.00000001     63.5     39     51
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IEA:InterPro.
78Q99755    562   PI51A_HUMAN Phosphatidylinositol 4-phosphate ...1920.00000002     63.5     28     42GO:0005737; C:cytoplasm; IDA:HPA.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0016607; C:nuclear speck; IDA:UniProtKB.::GO:0032587; C:ruffle membrane; IDA:UniProtKB.
GO:0016308; F:1-phosphatidylinositol-4-phosphate 5-kinase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019900; F:kinase binding; IDA:UniProtKB.
GO:0031532; P:actin cytoskeleton reorganization; IMP:UniProtKB.::GO:0032863; P:activation of Rac GTPase activity; IMP:UniProtKB.::GO:0060326; P:cell chemotaxis; IMP:UniProtKB.::GO:0048041; P:focal adhesion assembly; IMP:UniProtKB.::GO:0030216; P:keratinocyte differentiation; TAS:UniProtKB.::GO:0006909; P:phagocytosis; TAS:UniProtKB.::GO:0008654; P:phospholipid biosynthetic process; IDA:UniProtKB.::GO:0072661; P:protein targeting to plasma membrane; IMP:UniProtKB.::GO:0097178; P:ruffle assembly; IMP:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc.
79O70161    661   PI51C_MOUSE Phosphatidylinositol 4-phosphate ...1700.00000002     63.5     30     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0001891; C:phagocytic cup; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.::GO:0001931; C:uropod; IEA:UniProtKB-SubCell.
GO:0016308; F:1-phosphatidylinositol-4-phosphate 5-kinase activity; IDA:MGI.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0007409; P:axonogenesis; IDA:MGI.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW.
80P38994    779   MSS4_YEAST Probable phosphatidylinositol 4-ph...2050.00000002     63.5     30     46GO:0005634; C:nucleus; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD.
GO:0016308; F:1-phosphatidylinositol-4-phosphate 5-kinase activity; IDA:SGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0031321; P:ascospore-type prospore assembly; IGI:SGD.
81Q9HCC9    887   LST2_HUMAN Lateral signaling target protein 2...600.00000002     63.5     45     58GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0031901; C:early endosome membrane; IDA:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IMP:UniProtKB.
82Q5I6B8    688   PI51C_RAT Phosphatidylinositol 4-phosphate 5-...1700.00000002     63.2     30     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0001891; C:phagocytic cup; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.::GO:0001931; C:uropod; IEA:UniProtKB-SubCell.
GO:0016308; F:1-phosphatidylinositol-4-phosphate 5-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW.
83P61112    548   THSA_THEK1 Thermosome subunit alpha OS=Thermo...2750.00000003     62.8     24     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.
84P61111    548   THSA_PYRKO Thermosome subunit alpha OS=(Therm...2750.00000003     62.8     24     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.
85Q9V2T3    502   THSB_DESMO Thermosome subunit beta OS=Desulfu...2690.00000003     62.4     23     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.
86O13853    742   ITS3_SCHPO Phosphatidylinositol 4-phosphate 5...1820.00000003     62.8     27     49GO:0030428; C:cell septum; IDA:PomBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:PomBase.
GO:0016308; F:1-phosphatidylinositol-4-phosphate 5-kinase activity; IGI:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006651; P:diacylglycerol biosynthetic process; IC:PomBase.::GO:0071775; P:regulation of cell cycle cytokinesis; IMP:PomBase.
87Q9M1K2    779   PI5K4_ARATH Phosphatidylinositol 4-phosphate ...1730.00000003     62.8     31     50GO:0016324; C:apical plasma membrane; IDA:TAIR.::GO:0044445; C:cytosolic part; IDA:TAIR.::GO:0090406; C:pollen tube; IDA:TAIR.
GO:0016308; F:1-phosphatidylinositol-4-phosphate 5-kinase activity; IDA:TAIR.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IMP:TAIR.::GO:0007164; P:establishment of tissue polarity; IMP:TAIR.::GO:0009827; P:plant-type cell wall modification; IMP:TAIR.::GO:0009846; P:pollen germination; IGI:TAIR.::GO:0009860; P:pollen tube growth; IMP:TAIR.::GO:0010118; P:stomatal movement; IMP:TAIR.
88Q5R488    421   PI42C_PONAB Phosphatidylinositol 5-phosphate ...1950.00000003     62     27     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0016309; F:1-phosphatidylinositol-5-phosphate 4-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
89O88377    416   PI42B_RAT Phosphatidylinositol 5-phosphate 4-...1830.00000003     62     27     51GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0016309; F:1-phosphatidylinositol-5-phosphate 4-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
90O13010    406   PI42A_PIG Phosphatidylinositol 5-phosphate 4-...1830.00000004     61.6     27     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0016309; F:1-phosphatidylinositol-5-phosphate 4-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
91Q91ZT5    766   FGD4_MOUSE FYVE, RhoGEF and PH domain-contain...850.00000004     62.4     31     51GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030175; C:filopodium; IDA:MGI.::GO:0030027; C:lamellipodium; IDA:MGI.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0030032; P:lamellipodium assembly; IDA:MGI.::GO:0030035; P:microspike assembly; IDA:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
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