Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFR010W
Length:
499
Number of sequences:
5887
Description:
YFR010W UBP6 SGDID:S000001906, Chr VI from 165067-166566, Genome Release 64-1-1, Verified ORF, "Ubiquitin-specific protease situated in the base subcomplex of the 26S proteasome, releases free ubiquitin from branched polyubiquitin chains; works in opposition to Hul5p polyubiquitin elongation activity; mutant has aneuploidy tolerance"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91P50101    1230   UBP15_YEAST Ubiquitin carboxyl-terminal hydro...2450.3     37.7     24     39GO:0005737; C:cytoplasm; IDA:SGD.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:SGD.
GO:0016579; P:protein deubiquitination; IC:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
92P35125    1406   UBP6_HUMAN Ubiquitin carboxyl-terminal hydrol...710.19     38.1     31     49GO:0005764; C:lysosome; TAS:ProtInc.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0055037; C:recycling endosome; IDA:UniProtKB.
GO:0005516; F:calmodulin binding; IPI:UniProtKB.::GO:0004197; F:cysteine-type endopeptidase activity; TAS:UniProtKB.::GO:0003676; F:nucleic acid binding; TAS:ProtInc.::GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0060627; P:regulation of vesicle-mediated transport; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
93Q2UUG8    754   CREB_ASPOR Probable ubiquitin carboxyl-termin...790.89     35.8     28     44
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
GO:0045013; P:carbon catabolite repression of transcription; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
94Q9VYQ8    1129   UBP7_DROME Ubiquitin carboxyl-terminal hydrol...640.02     41.2     36     52GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005700; C:polytene chromosome; IDA:FlyBase.::GO:0043234; C:protein complex; IPI:FlyBase.::GO:0035328; C:transcriptionally silent chromatin; IDA:FlyBase.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0006342; P:chromatin silencing; IGI:FlyBase.::GO:0016578; P:histone deubiquitination; IDA:FlyBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
95Q5U349    618   UBP2_RAT Ubiquitin carboxyl-terminal hydrolas...1200.001     45.1     28     44GO:0005813; C:centrosome; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.::GO:0048642; P:negative regulation of skeletal muscle tissue development; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0048643; P:positive regulation of skeletal muscle tissue development; IDA:UniProtKB.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
96F1SRY5    982   UBP37_PIG Ubiquitin carboxyl-terminal hydrola...2920.036     40.4     24     37
GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0035871; P:protein K11-linked deubiquitination; ISS:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
97Q8C0R0    979   UBP37_MOUSE Ubiquitin carboxyl-terminal hydro...290.095     39.3     48     72
GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0035871; P:protein K11-linked deubiquitination; ISS:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
98Q7JKC3    1135   UBP7_CAEEL Ubiquitin carboxyl-terminal hydrol...780.021     41.2     36     47GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0031581; P:hemidesmosome assembly; IGI:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
99Q86T82    979   UBP37_HUMAN Ubiquitin carboxyl-terminal hydro...2790.073     39.7     24     37GO:0005634; C:nucleus; IDA:LIFEdb.
GO:0004197; F:cysteine-type endopeptidase activity; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0035871; P:protein K11-linked deubiquitination; IDA:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
100E2RK09    981   UBP37_CANFA Ubiquitin carboxyl-terminal hydro...2790.071     39.7     24     37
GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0035871; P:protein K11-linked deubiquitination; ISS:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
101F1N5V1    981   UBP37_BOVIN Ubiquitin carboxyl-terminal hydro...2790.019     41.6     24     37
GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0035871; P:protein K11-linked deubiquitination; ISS:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
102O88623    613   UBP2_MOUSE Ubiquitin carboxyl-terminal hydrol...1200.002     44.7     28     44GO:0005938; C:cell cortex; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IDA:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
103Q9FPS4    859   UBP23_ARATH Ubiquitin carboxyl-terminal hydro...3240.22     38.1     23     36
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
104Q70CQ1    688   UBP49_HUMAN Ubiquitin carboxyl-terminal hydro...490.8     36.2     33     51GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
105B2GUZ1    961   UBP4_RAT Ubiquitin carboxyl-terminal hydrolas...1090.81     36.2     26     40GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0031397; P:negative regulation of protein ubiquitination; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0034394; P:protein localization at cell surface; ISS:UniProtKB.::GO:0031647; P:regulation of protein stability; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
106Q13107    963   UBP4_HUMAN Ubiquitin carboxyl-terminal hydrol...1150.34     37.4     26     40GO:0005764; C:lysosome; TAS:ProtInc.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0031685; F:adenosine receptor binding; IPI:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
GO:0031397; P:negative regulation of protein ubiquitination; IMP:UniProtKB.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0034394; P:protein localization at cell surface; IDA:UniProtKB.::GO:0031647; P:regulation of protein stability; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
107Q5RCD3    963   UBP4_PONAB Ubiquitin carboxyl-terminal hydrol...1600.33     37.4     26     40GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0031397; P:negative regulation of protein ubiquitination; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0034394; P:protein localization at cell surface; ISS:UniProtKB.::GO:0031647; P:regulation of protein stability; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
108Q9NVE5    1235   UBP40_HUMAN Ubiquitin carboxyl-terminal hydro...2530.003     44.3     23     43
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
109P35123    962   UBP4_MOUSE Ubiquitin carboxyl-terminal hydrol...1091.5     35.4     26     40GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0031397; P:negative regulation of protein ubiquitination; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0034394; P:protein localization at cell surface; ISS:UniProtKB.::GO:0031647; P:regulation of protein stability; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
110O75604    605   UBP2_HUMAN Ubiquitin carboxyl-terminal hydrol...1180.003     43.9     26     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0030332; F:cyclin binding; IPI:UniProtKB.::GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0050821; P:protein stabilization; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
111F6V6I0    846   UBP13_XENTR Ubiquitin carboxyl-terminal hydro...450.003     43.9     42     60
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
112P39967    754   UBP9_YEAST Ubiquitin carboxyl-terminal hydrol...310.023     41.2     48     68GO:0005737; C:cytoplasm; IC:SGD.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; TAS:SGD.
GO:0016579; P:protein deubiquitination; TAS:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
113Q9H9J4    1324   UBP42_HUMAN Ubiquitin carboxyl-terminal hydro...660.14     38.5     35     47
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
114Q09879    1108   UBP5_SCHPO Probable ubiquitin carboxyl-termin...720.007     42.7     35     54GO:0005829; C:cytosol; IDA:PomBase.::GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0030133; C:transport vesicle; IDA:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:PomBase.
GO:0006897; P:endocytosis; IMP:PomBase.::GO:0016579; P:protein deubiquitination; IDA:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
115Q01476    1272   UBP2_YEAST Ubiquitin carboxyl-terminal hydrol...660.041     40.4     30     53GO:0005737; C:cytoplasm; IC:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:SGD.
GO:0016579; P:protein deubiquitination; IDA:SGD.::GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:SGD.
116Q9FPT5    1083   UBP1_ARATH Ubiquitin carboxyl-terminal hydrol...1690.004     43.5     26     43
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
117E1B9W9    1333   UBP42_BOVIN Ubiquitin carboxyl-terminal hydro...660.19     38.1     33     47
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
118A2Q9N1    758   CREB_ASPNC Probable ubiquitin carboxyl-termin...790.97     35.8     28     44
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
GO:0045013; P:carbon catabolite repression of transcription; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
119Q9FPT1    1116   UBP12_ARATH Ubiquitin carboxyl-terminal hydro...310.4     37.4     45     61GO:0005829; C:cytosol; IDA:TAIR.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
120P38237    781   UBP14_YEAST Ubiquitin carboxyl-terminal hydro...560.004     43.5     41     57GO:0005737; C:cytoplasm; IC:SGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045721; P:negative regulation of gluconeogenesis; IMP:SGD.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:SGD.::GO:0016579; P:protein deubiquitination; TAS:SGD.
121Q9HBJ7    922   UBP29_HUMAN Ubiquitin carboxyl-terminal hydro...600.043     40.4     33     60
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; TAS:UniProtKB.
GO:0006464; P:protein modification process; NAS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
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