UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YFR010W

Length:

499

Number of sequences:

5887

Description:

YFR010W UBP6 SGDID:S000001906, Chr VI from 165067-166566, Genome Release 64-1-1, Verified ORF, "Ubiquitin-specific protease situated in the base subcomplex of the 26S proteasome, releases free ubiquitin from branched polyubiquitin chains; works in opposition to Hul5p polyubiquitin elongation activity; mutant has aneuploidy tolerance"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
61	Q5M981	370	UB12B_XENLA Ubiquitin carboxyl-terminal hydro...	75	0.014	41.6	31	49
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
62	A4FUN7	371	UBP12_DANRE Ubiquitin carboxyl-terminal hydro...	297	0.005	42.7	24	37
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
63	O75317	370	UBP12_HUMAN Ubiquitin carboxyl-terminal hydro...	75	0.013	41.6	31	49
									GO:0004197; F:cysteine-type endopeptidase activity; IMP:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
									GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
64	Q9FPS2	661	UBP25_ARATH Ubiquitin carboxyl-terminal hydro...	107	0.026	40.8	29	40
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
65	Q52KZ6	370	UB12A_XENLA Ubiquitin carboxyl-terminal hydro...	75	0.013	41.6	31	49
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
66	C0HB46	372	UBP12_SALSA Ubiquitin carboxyl-terminal hydro...	304	0.014	41.2	25	37
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
67	Q9D9M2	370	UBP12_MOUSE Ubiquitin carboxyl-terminal hydro...	334	0.012	41.6	22	37
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
68	A5D9H7	369	UBP12_BOVIN Ubiquitin carboxyl-terminal hydro...	317	0.009	42	21	39
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
69	B4KXJ5	1185	UBP36_DROMO Ubiquitin carboxyl-terminal hydro...	132	0.0002	47.8	27	44	GO:0005730; C:nucleolus; ISS:UniProtKB.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
									GO:0030718; P:germ-line stem cell maintenance; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
70	O24454	371	UBP3_ARATH Ubiquitin carboxyl-terminal hydrol...	34	0.003	43.5	53	65	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
71	Q5ZM45	1033	UBP48_CHICK Ubiquitin carboxyl-terminal hydro...	251	0.0006	46.2	25	41	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
72	Q3V0C5	1052	UBP48_MOUSE Ubiquitin carboxyl-terminal hydro...	258	0.002	44.7	25	40	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
73	Q86UV5	1035	UBP48_HUMAN Ubiquitin carboxyl-terminal hydro...	254	0.017	41.6	26	42	GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
74	Q6U7I1	1101	UBP7_CHICK Ubiquitin carboxyl-terminal hydrol...	120	0.002	44.7	30	49	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
									GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
75	Q09931	1307	UBPY_CAEEL Probable ubiquitin carboxyl-termin...	70	1.7	35	36	51
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
76	A5PMR2	897	UBP33_DANRE Ubiquitin carboxyl-terminal hydro...	159	0.026	40.8	23	40	GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
									GO:0007411; P:axon guidance; ISS:UniProtKB.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
77	Q9UTT1	1129	UBP21_SCHPO Ubiquitin carboxyl-terminal hydro...	66	0.5	37	32	52	GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0030133; C:transport vesicle; IDA:PomBase.
									GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:PomBase.
									GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006897; P:endocytosis; IMP:PomBase.::GO:0016579; P:protein deubiquitination; IDA:PomBase.::GO:0045859; P:regulation of protein kinase activity; IGI:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
78	Q76LT8	1036	UBP48_RAT Ubiquitin carboxyl-terminal hydrola...	257	0.035	40.4	24	39	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IDA:RGD.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
79	A6QNM7	912	UBP33_BOVIN Ubiquitin carboxyl-terminal hydro...	67	0.0007	46.2	36	57	GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
									GO:0007411; P:axon guidance; ISS:UniProtKB.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
80	Q6P9L4	685	UBP49_MOUSE Ubiquitin carboxyl-terminal hydro...	49	0.95	35.8	33	49
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
81	Q2KHV7	606	UBP2_BOVIN Ubiquitin carboxyl-terminal hydrol...	38	1.1	35.4	42	55	GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
82	Q6P8X6	390	UBP50_MOUSE Putative ubiquitin carboxyl-termi...	51	0.01	42	33	61
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
83	P39538	1254	UBP12_YEAST Ubiquitin carboxyl-terminal hydro...	66	1.4	35.4	36	53	GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
									GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; TAS:SGD.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
84	Q8TEY7	942	UBP33_HUMAN Ubiquitin carboxyl-terminal hydro...	111	0.002	44.3	32	41	GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0030891; C:VCB complex; TAS:UniProtKB.
									GO:0004197; F:cysteine-type endopeptidase activity; IMP:UniProtKB.::GO:0001664; F:G-protein coupled receptor binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; TAS:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
									GO:0007411; P:axon guidance; ISS:UniProtKB.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0071108; P:protein K48-linked deubiquitination; IDA:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; IDA:UniProtKB.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IMP:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:UniProtKB.
85	Q8R5K2	909	UBP33_MOUSE Ubiquitin carboxyl-terminal hydro...	147	0.001	45.1	29	41	GO:0044297; C:cell body; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
									GO:0007411; P:axon guidance; IMP:UniProtKB.::GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
86	Q5REG5	914	UBP33_PONAB Ubiquitin carboxyl-terminal hydro...	111	0.007	42.7	32	41	GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
									GO:0007411; P:axon guidance; ISS:UniProtKB.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
87	Q28CN3	892	UBP33_XENTR Ubiquitin carboxyl-terminal hydro...	111	0.052	40	28	42	GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
									GO:0007411; P:axon guidance; ISS:UniProtKB.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
88	B8NSV5	755	CREB_ASPFN Probable ubiquitin carboxyl-termin...	79	0.88	35.8	28	44
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
									GO:0045013; P:carbon catabolite repression of transcription; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
89	O57429	357	UBP2_CHICK Ubiquitin carboxyl-terminal hydrol...	51	0.047	39.7	33	55	GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:Roslin.
									GO:0016579; P:protein deubiquitination; IDA:Roslin.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
90	Q8L6Y1	797	UBP14_ARATH Ubiquitin carboxyl-terminal hydro...	42	0.0009	45.8	45	60	GO:0005829; C:cytosol; IDA:TAIR.
									GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.::GO:0016579; P:protein deubiquitination; IDA:TAIR.::GO:0048767; P:root hair elongation; IMP:TAIR.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
91	P50101	1230	UBP15_YEAST Ubiquitin carboxyl-terminal hydro...	245	0.3	37.7	24	39	GO:0005737; C:cytoplasm; IDA:SGD.
									GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:SGD.
									GO:0016579; P:protein deubiquitination; IC:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.

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