Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFR010W
Length:
499
Number of sequences:
5887
Description:
YFR010W UBP6 SGDID:S000001906, Chr VI from 165067-166566, Genome Release 64-1-1, Verified ORF, "Ubiquitin-specific protease situated in the base subcomplex of the 26S proteasome, releases free ubiquitin from branched polyubiquitin chains; works in opposition to Hul5p polyubiquitin elongation activity; mutant has aneuploidy tolerance"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31A6NNY8    438   UBP27_HUMAN Ubiquitin carboxyl-terminal hydro...4330.000002     53.9     23     34
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
32Q8CEG8    438   UBP27_MOUSE Ubiquitin carboxyl-terminal hydro...4300.000002     53.9     23     34
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
33Q6GNI6    523   UB22A_XENLA Ubiquitin carboxyl-terminal hydro...4350.000002     53.9     22     35GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
34P57080    1055   UBP25_MOUSE Ubiquitin carboxyl-terminal hydro...660.006     43.1     38     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
35O00507    2555   USP9Y_HUMAN Probable ubiquitin carboxyl-termi...4420.000003     53.9     23     36GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0070410; F:co-SMAD binding; ISS:BHF-UCL.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; TAS:ProtInc.
GO:0030509; P:BMP signaling pathway; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; TAS:ProtInc.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
36Q93008    2570   USP9X_HUMAN Probable ubiquitin carboxyl-termi...4420.000004     53.5     23     36GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0070410; F:co-SMAD binding; IPI:BHF-UCL.::GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0030509; P:BMP signaling pathway; IDA:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007292; P:female gamete generation; TAS:ProtInc.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
37Q01477    912   UBP3_YEAST Ubiquitin carboxyl-terminal hydrol...690.000004     53.1     43     59GO:0005737; C:cytoplasm; IC:SGD.
GO:0003729; F:mRNA binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:SGD.
GO:0016579; P:protein deubiquitination; IDA:SGD.::GO:0060628; P:regulation of ER to Golgi vesicle-mediated transport; IMP:SGD.::GO:0047484; P:regulation of response to osmotic stress; IMP:SGD.::GO:0034517; P:ribophagy; IMP:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
38Q9QZL6    566   UBP21_MOUSE Ubiquitin carboxyl-terminal hydro...560.37     37     34     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IC:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019784; F:NEDD8-specific protease activity; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0016578; P:histone deubiquitination; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
39Q91W36    520   UBP3_MOUSE Ubiquitin carboxyl-terminal hydrol...1272.4     34.7     25     43
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
40P50102    471   UBP8_YEAST Ubiquitin carboxyl-terminal hydrol...570.000007     52     40     67GO:0071819; C:DUBm complex; IDA:SGD.::GO:0000124; C:SAGA complex; IDA:SGD.::GO:0046695; C:SLIK (SAGA-like) complex; IDA:SGD.
GO:0032947; F:protein complex scaffold; IDA:SGD.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IMP:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016578; P:histone deubiquitination; IMP:SGD.::GO:0051568; P:histone H3-K4 methylation; IMP:SGD.::GO:0034729; P:histone H3-K79 methylation; IMP:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
41A3AF13    1079   UBP26_ORYSJ Ubiquitin carboxyl-terminal hydro...600.0003     47.4     38     62GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
42A2XDG4    1079   UBP26_ORYSI Ubiquitin carboxyl-terminal hydro...600.0003     47.4     38     62GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
43Q5DU02    525   UBP22_MOUSE Ubiquitin carboxyl-terminal hydro...4360.00001     51.6     23     35
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IC:MGI.
44Q11119    775   UBP14_SCHPO Ubiquitin carboxyl-terminal hydro...461.1     35.8     35     57GO:0005654; C:nucleoplasm; IDA:PomBase.
GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:PomBase.::GO:0016579; P:protein deubiquitination; IDA:PomBase.
45Q9UK80    565   UBP21_HUMAN Ubiquitin carboxyl-terminal hydro...560.33     37.4     34     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019784; F:NEDD8-specific protease activity; IDA:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
GO:0016578; P:histone deubiquitination; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
46B2GUX4    565   UBP21_RAT Ubiquitin carboxyl-terminal hydrola...560.32     37.4     34     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019784; F:NEDD8-specific protease activity; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0016578; P:histone deubiquitination; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
47Q2KJ72    565   UBP21_BOVIN Ubiquitin carboxyl-terminal hydro...560.29     37.4     34     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019784; F:NEDD8-specific protease activity; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0016578; P:histone deubiquitination; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
48Q5RE63    375   UBP18_PONAB Ubl carboxyl-terminal hydrolase 1...2520.006     42.7     21     39
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
49O42726    1220   UBP2_KLULA Ubiquitin carboxyl-terminal hydrol...570.017     41.6     33     53
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
50Q9UMW8    372   UBP18_HUMAN Ubl carboxyl-terminal hydrolase 1...2510.00007     48.5     22     41GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:LIFEdb.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; TAS:ProtInc.
GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.::GO:0060337; P:type I interferon-mediated signaling pathway; TAS:Reactome.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
51O74442    457   UBP16_SCHPO Probable ubiquitin carboxyl-termi...710.00003     50.1     38     52GO:0005730; C:nucleolus; IDA:PomBase.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:PomBase.
GO:0016579; P:protein deubiquitination; IDA:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
52Q9Y6I4    520   UBP3_HUMAN Ubiquitin carboxyl-terminal hydrol...1272.7     34.3     24     39GO:0000790; C:nuclear chromatin; IDA:UniProtKB.
GO:0042393; F:histone binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IMP:UniProtKB.::GO:0016578; P:histone deubiquitination; IDA:UniProtKB.::GO:0000278; P:mitotic cell cycle; IMP:UniProtKB.::GO:0031647; P:regulation of protein stability; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
53Q7ZUM8    695   UBP44_DANRE Ubiquitin carboxyl-terminal hydro...4290.00004     50.1     20     36GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051322; P:anaphase; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0021551; P:central nervous system morphogenesis; IMP:ZFIN.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0090231; P:regulation of spindle checkpoint; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
54Q6A4J8    1103   UBP7_MOUSE Ubiquitin carboxyl-terminal hydrol...1310.002     44.7     30     48GO:0005737; C:cytoplasm; IDA:MGI.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
55B4IXE0    1240   UBP36_DROGR Ubiquitin carboxyl-terminal hydro...2920.00005     49.7     24     43GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
GO:0030718; P:germ-line stem cell maintenance; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
56Q3LFD5    358   UBP41_HUMAN Putative ubiquitin carboxyl-termi...2500.002     43.9     21     41
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
57Q8LAM0    365   UBP4_ARATH Ubiquitin carboxyl-terminal hydrol...1180.012     41.6     29     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
58B4LG38    1214   UBP36_DROVI Ubiquitin carboxyl-terminal hydro...2880.00008     49.3     24     43GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
GO:0030718; P:germ-line stem cell maintenance; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
59Q4VSI4    1103   UBP7_RAT Ubiquitin carboxyl-terminal hydrolas...1310.002     44.7     30     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0006917; P:induction of apoptosis; IDA:RGD.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0031647; P:regulation of protein stability; IDA:RGD.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
60Q93009    1102   UBP7_HUMAN Ubiquitin carboxyl-terminal hydrol...1310.002     44.7     30     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.::GO:0002039; F:p53 binding; IDA:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
61Q5M981    370   UB12B_XENLA Ubiquitin carboxyl-terminal hydro...750.014     41.6     31     49
GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
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