Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFR010W
Length:
499
Number of sequences:
5887
Description:
YFR010W UBP6 SGDID:S000001906, Chr VI from 165067-166566, Genome Release 64-1-1, Verified ORF, "Ubiquitin-specific protease situated in the base subcomplex of the 26S proteasome, releases free ubiquitin from branched polyubiquitin chains; works in opposition to Hul5p polyubiquitin elongation activity; mutant has aneuploidy tolerance"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
181B3NC86    1085   UBP36_DROER Ubiquitin carboxyl-terminal hydro...492.5     34.7     29     47GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
GO:0030718; P:germ-line stem cell maintenance; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
182A5PN09    911   UBP20_DANRE Ubiquitin carboxyl-terminal hydro...1110.2     38.1     27     40GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
183B4PIW8    1082   UBP36_DROYA Ubiquitin carboxyl-terminal hydro...492.6     34.7     29     47GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
GO:0030718; P:germ-line stem cell maintenance; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
184Q9P7S5    875   UBP7_SCHPO Probable ubiquitin carboxyl-termin...1090.051     40     30     42GO:0005829; C:cytosol; IDA:PomBase.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016579; P:protein deubiquitination; IDA:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
185Q9VRP5    1085   UBP36_DROME Ubiquitin carboxyl-terminal hydro...491.7     35     31     47GO:0005730; C:nucleolus; IDA:UniProtKB.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.
GO:0030718; P:germ-line stem cell maintenance; IMP:UniProtKB.::GO:0016578; P:histone deubiquitination; IDA:FlyBase.::GO:0045824; P:negative regulation of innate immune response; IMP:FlyBase.::GO:0042981; P:regulation of apoptotic process; IMP:FlyBase.::GO:0035019; P:somatic stem cell maintenance; IMP:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
186Q99K46    921   UBP11_MOUSE Ubiquitin carboxyl-terminal hydro...1150.092     39.3     26     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
187Q7RTZ2    530   U17L1_HUMAN Putative ubiquitin carboxyl-termi...660.076     39.3     36     53GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
188O94269    512   UBP3_SCHPO Probable ubiquitin carboxyl-termin...870.056     39.7     25     48GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:PomBase.
GO:0016579; P:protein deubiquitination; IDA:PomBase.::GO:0060628; P:regulation of ER to Golgi vesicle-mediated transport; ISS:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
189B4HUI5    1059   UBP36_DROSE Ubiquitin carboxyl-terminal hydro...491.3     35.4     31     49GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
GO:0030718; P:germ-line stem cell maintenance; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
190B4QIS3    988   UBP36_DROSI Ubiquitin carboxyl-terminal hydro...490.94     35.8     31     49GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
GO:0030718; P:germ-line stem cell maintenance; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
191E1BMF7    863   UBP13_BOVIN Ubiquitin carboxyl-terminal hydro...1310.19     38.1     25     44
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
192A0JM59    884   UBP20_XENTR Ubiquitin carboxyl-terminal hydro...300.64     36.6     50     60GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
193Q6J1Y9    1357   UBP19_RAT Ubiquitin carboxyl-terminal hydrola...1660.064     39.7     23     37GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030433; P:ER-associated protein catabolic process; ISS:UniProtKB.::GO:0048642; P:negative regulation of skeletal muscle tissue development; ISS:UniProtKB.::GO:0090068; P:positive regulation of cell cycle process; IMP:UniProtKB.::GO:0016579; P:protein deubiquitination; IMP:UniProtKB.::GO:1900037; P:regulation of cellular response to hypoxia; ISS:UniProtKB.::GO:0031647; P:regulation of protein stability; IDA:UniProtKB.::GO:0034976; P:response to endoplasmic reticulum stress; ISS:UniProtKB.::GO:0014732; P:skeletal muscle atrophy; IEP:UniProtKB.
194B1WBD7    840   UBP20_XENLA Ubiquitin carboxyl-terminal hydro...300.67     36.2     50     60GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
195Q5BKP2    858   UBP13_MOUSE Ubiquitin carboxyl-terminal hydro...1310.2     38.1     25     44
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
196Q3UJD6    1360   UBP19_MOUSE Ubiquitin carboxyl-terminal hydro...1660.068     39.7     23     37GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030433; P:ER-associated protein catabolic process; ISS:UniProtKB.::GO:0048642; P:negative regulation of skeletal muscle tissue development; IMP:UniProtKB.::GO:0090068; P:positive regulation of cell cycle process; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:1900037; P:regulation of cellular response to hypoxia; ISS:UniProtKB.::GO:0031647; P:regulation of protein stability; ISS:UniProtKB.::GO:0034976; P:response to endoplasmic reticulum stress; ISS:UniProtKB.::GO:0014732; P:skeletal muscle atrophy; ISS:UniProtKB.
197A7Z056    912   UBP20_BOVIN Ubiquitin carboxyl-terminal hydro...300.36     37.4     50     60GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
198Q9FIQ1    732   UBP21_ARATH Ubiquitin carboxyl-terminal hydro...690.08     39.3     29     49
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
199A6NCW7    530   U17L4_HUMAN Inactive ubiquitin carboxyl-termi...440.18     38.1     34     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
200O60079    979   UBP12_SCHPO Probable ubiquitin carboxyl-termi...637.5     33.1     35     52GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:PomBase.
GO:0016579; P:protein deubiquitination; IDA:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
201F1QFS9    860   UBP13_DANRE Ubiquitin carboxyl-terminal hydro...1300.3     37.4     24     42
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
202P0C7H9    530   U17L7_HUMAN Inactive ubiquitin carboxyl-termi...430.091     38.9     35     63GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
203Q92995    863   UBP13_HUMAN Ubiquitin carboxyl-terminal hydro...1310.21     38.1     25     44
GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
204P45974    858   UBP5_HUMAN Ubiquitin carboxyl-terminal hydrol...450.15     38.5     38     51GO:0005764; C:lysosome; TAS:ProtInc.
GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004221; F:ubiquitin thiolesterase activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; IMP:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
205Q9BXU7    913   UBP26_HUMAN Ubiquitin carboxyl-terminal hydro...622.6     34.7     32     58GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
206Q9ZSB5    923   UBP10_ARATH Ubiquitin carboxyl-terminal hydro...690.81     36.2     35     51
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
207P56399    858   UBP5_MOUSE Ubiquitin carboxyl-terminal hydrol...1350.26     37.7     23     42
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
208O94966    1318   UBP19_HUMAN Ubiquitin carboxyl-terminal hydro...1660.1     39.3     23     37GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030433; P:ER-associated protein catabolic process; IDA:UniProtKB.::GO:0048642; P:negative regulation of skeletal muscle tissue development; ISS:UniProtKB.::GO:0090068; P:positive regulation of cell cycle process; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:1900037; P:regulation of cellular response to hypoxia; IMP:UniProtKB.::GO:0031647; P:regulation of protein stability; ISS:UniProtKB.::GO:0034976; P:response to endoplasmic reticulum stress; IEP:UniProtKB.::GO:0014732; P:skeletal muscle atrophy; ISS:UniProtKB.
209Q5FWT7    318   UBCP1_RAT Ubiquitin-like domain-containing CT...930.11     38.5     33     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
210Q8BGR9    318   UBCP1_MOUSE Ubiquitin-like domain-containing ...930.11     38.5     33     53
GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
211Q9P3U0    1141   UBP2_SCHPO Probable ubiquitin carboxyl-termin...320.13     38.9     44     69GO:0005829; C:cytosol; IDA:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:PomBase.
GO:0016579; P:protein deubiquitination; IDA:PomBase.::GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; ISS:PomBase.
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