Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFR004W
Length:
306
Number of sequences:
5887
Description:
YFR004W RPN11 SGDID:S000001900, Chr VI from 153393-154313, Genome Release 64-1-1, Verified ORF, "Metalloprotease subunit of the 19S regulatory particle of the 26S proteasome lid; couples the deubiquitination and degradation of proteasome substrates; involved, independent of catalytic activity, in fission of mitochondria and peroxisomes"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q4VA72    261   BRCC3_XENTR Lys-63-specific deubiquitinase BR...1200.00000002     57.8     32     48GO:0070531; C:BRCA1-A complex; ISS:UniProtKB.::GO:0070552; C:BRISC complex; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; ISS:UniProtKB.::GO:0031593; F:polyubiquitin binding; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0070537; P:histone H2A K63-linked deubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
62Q170C2    336   EIF3H_AEDAE Eukaryotic translation initiation...1420.00000003     57.8     32     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
63A5PJP6    316   BRCC3_BOVIN Lys-63-specific deubiquitinase BR...1730.00000005     57     26     41GO:0070531; C:BRCA1-A complex; ISS:UniProtKB.::GO:0070552; C:BRISC complex; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; ISS:UniProtKB.::GO:0031593; F:polyubiquitin binding; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0070537; P:histone H2A K63-linked deubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
64P46737    291   BRCC3_MOUSE Lys-63-specific deubiquitinase BR...1730.00000008     56.2     25     41GO:0070531; C:BRCA1-A complex; ISS:UniProtKB.::GO:0070552; C:BRISC complex; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; ISS:UniProtKB.::GO:0031593; F:polyubiquitin binding; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0070537; P:histone H2A K63-linked deubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
65B0KWU8    316   BRCC3_CALJA Lys-63-specific deubiquitinase BR...1730.00000009     56.2     27     42GO:0070531; C:BRCA1-A complex; ISS:UniProtKB.::GO:0070552; C:BRISC complex; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; ISS:UniProtKB.::GO:0031593; F:polyubiquitin binding; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0070537; P:histone H2A K63-linked deubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
66Q5R9L6    247   BRCC3_PONAB Lys-63-specific deubiquitinase BR...1730.00000009     55.8     27     42GO:0070531; C:BRCA1-A complex; ISS:UniProtKB.::GO:0070552; C:BRISC complex; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; ISS:UniProtKB.::GO:0031593; F:polyubiquitin binding; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0070537; P:histone H2A K63-linked deubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
67B4JAS7    337   EIF3H_DROGR Eukaryotic translation initiation...1510.00000009     56.2     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
68Q5F3F2    832   MYSM1_CHICK Histone H2A deubiquitinase MYSM1 ...1160.0000001     57     34     49GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0016578; P:histone deubiquitination; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
69B0WDA9    336   EIF3H_CULQU Eukaryotic translation initiation...1420.0000001     56.2     32     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
70Q96FJ0    436   STALP_HUMAN AMSH-like protease OS=Homo sapien...1220.0000001     55.8     29     49
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
71P46736    316   BRCC3_HUMAN Lys-63-specific deubiquitinase BR...1730.0000002     55.5     27     42GO:0070531; C:BRCA1-A complex; IDA:UniProtKB.::GO:0070552; C:BRISC complex; IDA:UniProtKB.::GO:0000152; C:nuclear ubiquitin ligase complex; IDA:UniProtKB.
GO:0030234; F:enzyme regulator activity; IDA:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IMP:UniProtKB.::GO:0031593; F:polyubiquitin binding; IDA:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; IMP:UniProtKB.
GO:0006302; P:double-strand break repair; IMP:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0070537; P:histone H2A K63-linked deubiquitination; IDA:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; IMP:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0010165; P:response to X-ray; IDA:MGI.
72Q54UD0    319   EIF3H_DICDI Eukaryotic translation initiation...1370.0000002     55.5     26     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0006446; P:regulation of translational initiation; ISS:dictyBase.
73B5DJJ2    337   EIF3H_DROPS Eukaryotic translation initiation...1410.0000002     55.5     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
74B3N4F1    338   EIF3H_DROER Eukaryotic translation initiation...1410.0000002     55.5     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
75B6MUN4    809   MYSM1_BRAFL Histone H2A deubiquitinase MYSM1 ...1280.0000002     55.8     33     47GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0016578; P:histone deubiquitination; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
76Q9U9Q4    338   EIF3H_DROME Eukaryotic translation initiation...1410.0000002     55.5     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
77B4P3T9    338   EIF3H_DROYA Eukaryotic translation initiation...1410.0000002     55.5     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
78B4I1C2    338   EIF3H_DROSE Eukaryotic translation initiation...1410.0000002     55.1     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
79B3MP94    337   EIF3H_DROAN Eukaryotic translation initiation...1410.0000002     55.1     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
80B4LTW0    337   EIF3H_DROVI Eukaryotic translation initiation...1410.0000003     54.7     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
81Q9GV27    337   EIF3H_BOMMO Eukaryotic translation initiation...1550.0000006     53.9     27     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
82A9V3P1    354   EIF3H_MONBE Eukaryotic translation initiation...1400.0000007     53.9     25     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
83Q76N33    436   STALP_MOUSE AMSH-like protease OS=Mus musculu...1220.0000007     53.9     29     48
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
84B4KGS4    337   EIF3H_DROMO Eukaryotic translation initiation...1410.0000007     53.5     29     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
85Q5BDW0    366   EIF3H_EMENI Eukaryotic translation initiation...1500.0000007     53.5     27     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
86Q5VVJ2    828   MYSM1_HUMAN Histone H2A deubiquitinase MYSM1 ...1220.000001     53.9     33     48GO:0016585; C:chromatin remodeling complex; IDA:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IMP:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
GO:0016578; P:histone deubiquitination; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
87A4QT78    363   EIF3H_MAGO7 Eukaryotic translation initiation...1640.000002     52.4     24     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
88B4N116    337   EIF3H_DROWI Eukaryotic translation initiation...1350.000002     52     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
89Q9P371    435   SST2_SCHPO AMSH-like protease sst2 OS=Schizos...680.000003     52     34     59GO:0032153; C:cell division site; IDA:PomBase.::GO:0005768; C:endosome; IDA:PomBase.::GO:0030133; C:transport vesicle; IDA:PomBase.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:PomBase.::GO:0004843; F:ubiquitin-specific protease activity; IDA:PomBase.
GO:0006897; P:endocytosis; IMP:PomBase.::GO:0016579; P:protein deubiquitination; IDA:PomBase.::GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:PomBase.
90A0JMR6    818   MYSM1_XENLA Histone H2A deubiquitinase MYSM1 ...1150.000003     52.4     32     51GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0016578; P:histone deubiquitination; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
91A7E7B3    367   EIF3H_SCLS1 Eukaryotic translation initiation...1600.000003     52     24     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
records
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