Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFR004W
Length:
306
Number of sequences:
5887
Description:
YFR004W RPN11 SGDID:S000001900, Chr VI from 153393-154313, Genome Release 64-1-1, Verified ORF, "Metalloprotease subunit of the 19S regulatory particle of the 26S proteasome lid; couples the deubiquitination and degradation of proteasome substrates; involved, independent of catalytic activity, in fission of mitochondria and peroxisomes"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P0CQ25    371   CSN5_CRYNB COP9 signalosome complex subunit 5...2041e-31     125     37     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IEA:UniProtKB-KW.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
32O94454    299   CSN5_SCHPO COP9 signalosome complex subunit 5...2075e-31     123     36     55GO:0005829; C:cytosol; IDA:PomBase.::GO:0008180; C:signalosome; IDA:PomBase.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0010388; P:cullin deneddylation; IGI:PomBase.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
33Q59PG6    213   CSN5_CANAL COP9 signalosome complex subunit 5...1402e-26     108     39     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IEA:UniProtKB-KW.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
34Q75E19    420   CSN5_ASHGO COP9 signalosome complex subunit 5...1843e-24     104     33     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IEA:UniProtKB-KW.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
35Q6CRJ8    373   CSN5_KLULA COP9 signalosome complex subunit 5...1342e-22     99.4     37     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IEA:UniProtKB-KW.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
36A6ZXB7    440   CSN5_YEAS7 COP9 signalosome complex subunit 5...1509e-20     92.4     34     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IEA:UniProtKB-KW.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
37Q12468    440   CSN5_YEAST COP9 signalosome complex subunit 5...1509e-20     92.4     34     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IDA:SGD.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IMP:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0000754; P:adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion; IMP:SGD.::GO:0010388; P:cullin deneddylation; IMP:SGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
38B3LH96    440   CSN5_YEAS1 COP9 signalosome complex subunit 5...1509e-20     92.4     34     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IEA:UniProtKB-KW.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
39Q6FT36    465   CSN5_CANGA COP9 signalosome complex subunit 5...1415e-19     90.5     35     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IEA:UniProtKB-KW.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
40Q6AXJ2    335   EI3HA_DANRE Eukaryotic translation initiation...1550.0000000001     65.5     29     55GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:UniProtKB.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0007420; P:brain development; IMP:ZFIN.::GO:0048882; P:lateral line development; IMP:ZFIN.::GO:0001944; P:vasculature development; IMP:ZFIN.
41Q5ZLE6    348   EIF3H_CHICK Eukaryotic translation initiation...1740.0000000001     65.5     30     53GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:UniProtKB.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
42Q5PPY6    334   EIF3H_XENLA Eukaryotic translation initiation...1340.0000000002     64.3     31     57GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:UniProtKB.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
43Q6P381    335   EIF3H_XENTR Eukaryotic translation initiation...1490.0000000002     64.3     30     55GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:UniProtKB.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
44B5RI54    344   EIF3H_SALSA Eukaryotic translation initiation...1410.0000000002     64.3     30     55GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:UniProtKB.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
45B5FY35    348   EIF3H_TAEGU Eukaryotic translation initiation...1680.0000000004     63.5     29     53GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:UniProtKB.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
46Q6P9U8    352   EIF3H_RAT Eukaryotic translation initiation f...1680.0000000005     63.2     29     53GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:UniProtKB.::GO:0005792; C:microsome; IDA:RGD.
GO:0032403; F:protein complex binding; IDA:RGD.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
47O15372    352   EIF3H_HUMAN Eukaryotic translation initiation...1680.0000000008     62.8     29     53GO:0005829; C:cytosol; TAS:Reactome.::GO:0005852; C:eukaryotic translation initiation factor 3 complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0006446; P:regulation of translational initiation; TAS:UniProtKB.
48Q91WK2    352   EIF3H_MOUSE Eukaryotic translation initiation...1410.0000000009     62.4     29     55GO:0005852; C:eukaryotic translation initiation factor 3 complex; IDA:UniProtKB.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
49Q56JZ5    352   EIF3H_BOVIN Eukaryotic translation initiation...1410.0000000009     62.4     29     55GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:UniProtKB.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
50A7SA47    332   EIF3H_NEMVE Eukaryotic translation initiation...1400.000000001     62     26     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
51B5X8M4    260   BRCC3_SALSA Lys-63-specific deubiquitinase BR...1400.000000002     60.8     29     48GO:0070531; C:BRCA1-A complex; ISS:UniProtKB.::GO:0070552; C:BRISC complex; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; ISS:UniProtKB.::GO:0031593; F:polyubiquitin binding; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0070537; P:histone H2A K63-linked deubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
52Q5PR67    333   EI3HB_DANRE Eukaryotic translation initiation...1410.000000002     61.6     28     55GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:UniProtKB.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0007420; P:brain development; IMP:ZFIN.::GO:0007507; P:heart development; IMP:ZFIN.
53Q7PVR3    334   EIF3H_ANOGA Eukaryotic translation initiation...1410.000000002     61.2     31     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
54Q6NKP9    223   AMSH2_ARATH AMSH-like ubiquitin thioesterase ...1180.000000004     59.3     31     50
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
55Q54Q40    715   D1039_DICDI Probable ubiquitin thioesterase D...1200.000000004     61.2     28     51
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
56B2RYM5    291   BRCC3_RAT Lys-63-specific deubiquitinase BRCC...1620.000000004     60.1     27     41GO:0070531; C:BRCA1-A complex; ISS:UniProtKB.::GO:0070552; C:BRISC complex; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; ISS:UniProtKB.::GO:0031593; F:polyubiquitin binding; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0070537; P:histone H2A K63-linked deubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
57Q66GV6    261   BRCC3_XENLA Lys-63-specific deubiquitinase BR...1290.00000001     58.2     29     46GO:0070531; C:BRCA1-A complex; ISS:UniProtKB.::GO:0070552; C:BRISC complex; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; ISS:UniProtKB.::GO:0031593; F:polyubiquitin binding; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0070537; P:histone H2A K63-linked deubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
58Q5R558    436   STALP_PONAB AMSH-like protease OS=Pongo abeli...1220.00000002     58.9     30     50
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
59Q7M757    291   BRC3L_MOUSE Lys-63-specific deubiquitinase BR...1650.00000002     58.5     28     42GO:0070531; C:BRCA1-A complex; ISS:UniProtKB.::GO:0070552; C:BRISC complex; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; ISS:UniProtKB.::GO:0031593; F:polyubiquitin binding; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0070537; P:histone H2A K63-linked deubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
60Q9C5Z2    337   EIF3H_ARATH Eukaryotic translation initiation...1350.00000002     58.5     28     49GO:0005829; C:cytosol; IDA:TAIR.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
61Q4VA72    261   BRCC3_XENTR Lys-63-specific deubiquitinase BR...1200.00000002     57.8     32     48GO:0070531; C:BRCA1-A complex; ISS:UniProtKB.::GO:0070552; C:BRISC complex; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; ISS:UniProtKB.::GO:0031593; F:polyubiquitin binding; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0070537; P:histone H2A K63-linked deubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
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