Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFL044C
Length:
301
Number of sequences:
5887
Description:
YFL044C OTU1 SGDID:S000001850, Chr VI from 45560-44655, Genome Release 64-1-1, reverse complement, Verified ORF, "Deubiquitylation enzyme that binds to the chaperone-ATPase Cdc48p; may contribute to regulation of protein degradation by deubiquitylating substrates that have been ubiquitylated by Ufd2p; member of the Ovarian Tumor (OTU) family"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P43558    301   OTU1_YEAST Ubiquitin thioesterase OTU1 OS=Sac...3010     625     100     100GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0004843; F:ubiquitin-specific protease activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016579; P:protein deubiquitination; IDA:SGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IMP:SGD.
2Q5F3A6    302   OTU1_CHICK Ubiquitin thioesterase OTU1 OS=Gal...2826e-43     155     30     53GO:0005622; C:intracellular; IEA:InterPro.
GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006520; P:cellular amino acid metabolic process; ISS:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:UniProtKB.::GO:0030433; P:ER-associated protein catabolic process; ISS:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.
3Q567B1    301   OTU1_DANRE Ubiquitin thioesterase OTU1 OS=Dan...2932e-41     150     31     53
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0006520; P:cellular amino acid metabolic process; ISS:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:UniProtKB.::GO:0030433; P:ER-associated protein catabolic process; ISS:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.
4Q8CB27    343   OTU1_MOUSE Ubiquitin thioesterase OTU1 OS=Mus...2789e-41     150     33     51GO:0005622; C:intracellular; IEA:InterPro.
GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006520; P:cellular amino acid metabolic process; ISS:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:UniProtKB.::GO:0030433; P:ER-associated protein catabolic process; ISS:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.
5Q32Q05    343   OTU1_RAT Ubiquitin thioesterase OTU1 OS=Rattu...2785e-39     145     32     51GO:0005622; C:intracellular; IEA:InterPro.
GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006520; P:cellular amino acid metabolic process; ISS:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:UniProtKB.::GO:0030433; P:ER-associated protein catabolic process; ISS:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.
6Q5VVQ6    348   OTU1_HUMAN Ubiquitin thioesterase OTU1 OS=Hom...2786e-39     145     32     52GO:0005622; C:intracellular; IEA:InterPro.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006520; P:cellular amino acid metabolic process; ISS:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:UniProtKB.::GO:0030433; P:ER-associated protein catabolic process; IMP:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; IDA:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; IDA:UniProtKB.
7Q0IH43    304   OTU1_XENLA Ubiquitin thioesterase OTU1 OS=Xen...2869e-37     138     28     51GO:0005622; C:intracellular; IEA:InterPro.
GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006520; P:cellular amino acid metabolic process; ISS:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:UniProtKB.::GO:0030433; P:ER-associated protein catabolic process; ISS:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.
8Q05B57    348   OTU1_BOVIN Ubiquitin thioesterase OTU1 OS=Bos...2911e-36     139     31     51GO:0005622; C:intracellular; IEA:InterPro.
GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006520; P:cellular amino acid metabolic process; ISS:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:UniProtKB.::GO:0030433; P:ER-associated protein catabolic process; ISS:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.
9Q9VRJ9    347   OTU1_DROME Ubiquitin thioesterase OTU1 OS=Dro...3354e-35     135     30     47
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006520; P:cellular amino acid metabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
10O13974    329   OTU1_SCHPO Putative ubiquitin thioesterase ot...3356e-35     134     30     47GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004843; F:ubiquitin-specific protease activity; IDA:PomBase.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; IDA:PomBase.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
11Q29FC9    358   OTU1_DROPS Ubiquitin thioesterase OTU1 OS=Dro...3493e-33     130     30     44
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006520; P:cellular amino acid metabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
12Q55BI3    325   OTU1_DICDI Ubiquitin thioesterase OTU1 OS=Dic...3112e-32     127     28     49
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004843; F:ubiquitin-specific protease activity; ISS:dictyBase.
GO:0016579; P:protein deubiquitination; ISS:dictyBase.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0030587; P:sorocarp development; IMP:dictyBase.
13Q9UUK3    324   YLO3_SCHPO OTU domain-containing protein C195...1280.0002     46.2     28     48GO:0005829; C:cytosol; IDA:PomBase.
GO:0004843; F:ubiquitin-specific protease activity; IDA:PomBase.
GO:0016579; P:protein deubiquitination; IDA:PomBase.
14Q01804    1113   OTUD4_HUMAN OTU domain-containing protein 4 O...1130.006     42     27     44
15Q7RTX8    443   HIN1L_HUMAN Putative HIN1-like protein OS=Hom...1140.053     38.5     27     47
16Q8LBZ4    317   OTU_ARATH OTU domain-containing protein At3g5...1420.062     38.1     23     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
17P58816    265   MCRZ_METTM Methyl-coenzyme M reductase II sub...1390.079     37.7     27     47
GO:0050524; F:coenzyme-B sulfoethylthiotransferase activity; IEA:EC.
GO:0015948; P:methanogenesis; IEA:UniProtKB-KW.
18P21112    265   MCRZ_METTH Methyl-coenzyme M reductase II sub...1390.082     37.7     27     47
GO:0050524; F:coenzyme-B sulfoethylthiotransferase activity; IEA:EC.
GO:0015948; P:methanogenesis; IEA:UniProtKB-KW.
19B2RRE7    1107   OTUD4_MOUSE OTU domain-containing protein 4 O...1130.12     37.7     27     44
20P16112    2415   PGCA_HUMAN Aggrecan core protein OS=Homo sapi...320.22     37     47     69GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell.
GO:0005201; F:extracellular matrix structural constituent; TAS:UniProtKB.::GO:0005540; F:hyaluronic acid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007155; P:cell adhesion; IEA:InterPro.::GO:0006508; P:proteolysis; NAS:UniProtKB.::GO:0001501; P:skeletal system development; NAS:UniProtKB.
21Q5M8L0    294   OTU6B_XENTR OTU domain-containing protein 6B ...1420.31     35.8     21     42
22Q8N6M0    293   OTU6B_HUMAN OTU domain-containing protein 6B ...1370.4     35.4     24     42
23Q66431    4036   L_DUGBA RNA-directed RNA polymerase L OS=Dugb...1470.57     35.8     23     46
GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro.
24Q8K2H2    294   OTU6B_MOUSE OTU domain-containing protein 6B ...1370.83     34.7     23     41
25Q61247    491   A2AP_MOUSE Alpha-2-antiplasmin OS=Mus musculu...1411     34.7     23     43
GO:0004867; F:serine-type endopeptidase inhibitor activity; IBA:RefGenome.
GO:0006953; P:acute-phase response; IEA:UniProtKB-KW.::GO:0048514; P:blood vessel morphogenesis; IMP:BHF-UCL.::GO:0030199; P:collagen fibril organization; IMP:BHF-UCL.::GO:0045597; P:positive regulation of cell differentiation; IMP:BHF-UCL.::GO:0032967; P:positive regulation of collagen biosynthetic process; IMP:BHF-UCL.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0071636; P:positive regulation of transforming growth factor beta production; IMP:BHF-UCL.::GO:0002034; P:regulation of blood vessel size by renin-angiotensin; IMP:BHF-UCL.::GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
26Q7ZV00    293   OTU6B_DANRE OTU domain-containing protein 6B ...1421     34.3     21     44
27Q6GM06    294   OTU6B_XENLA OTU domain-containing protein 6B ...1401     34.3     21     41
28Q96KN3    472   PKNX2_HUMAN Homeobox protein PKNOX2 OS=Homo s...531.1     34.7     36     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
29Q8BG99    474   PKNX2_MOUSE Homeobox protein PKNOX2 OS=Mus mu...531.1     34.7     36     55GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0015630; C:microtubule cytoskeleton; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0051015; F:actin filament binding; IDA:MGI.::GO:0003785; F:actin monomer binding; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IGI:MGI.
30Q5R6L1    472   PKNX2_PONAB Homeobox protein PKNOX2 OS=Pongo ...531.1     34.3     36     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
31P39453    914   TORS_ECOLI Sensor protein torS OS=Escherichia...1132.3     33.5     26     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016868; F:intramolecular transferase activity, phosphotransferases; IMP:EcoCyc.::GO:0004721; F:phosphoprotein phosphatase activity; IMP:EcoCyc.::GO:0042803; F:protein homodimerization activity; IMP:EcoCyc.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.::GO:0000155; F:two-component sensor activity; IMP:EcoCyc.
GO:0009061; P:anaerobic respiration; IMP:EcoCyc.::GO:0071310; P:cellular response to organic substance; IMP:EcoCyc.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0046777; P:protein autophosphorylation; IMP:EcoCyc.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
records
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