Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFL031W
Length:
238
Number of sequences:
5887
Description:
YFL031W HAC1 SGDID:S000001863, Chr VI from 75179-75839,76092-76147, Genome Release 64-1-1, Verified ORF, "Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) that regulates the unfolded protein response, via UPRE binding, and membrane biogenesis; ER stress-induced splicing pathway facilitates efficient Hac1p synthesis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P18846    271   ATF1_HUMAN Cyclic AMP-dependent transcription...590.51     34.7     36     64
GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
32Q9VWW0    359   CREBB_DROME Cyclic AMP response element-bindi...410.51     35     37     71GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IDA:FlyBase.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0045475; P:locomotor rhythm; NAS:FlyBase.::GO:0007616; P:long-term memory; IDA:FlyBase.::GO:0072375; P:medium-term memory; IMP:FlyBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:FlyBase.::GO:0045187; P:regulation of circadian sleep/wake cycle, sleep; TAS:FlyBase.::GO:0030431; P:sleep; IMP:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
33P16951    487   ATF2_MOUSE Cyclic AMP-dependent transcription...490.56     35     35     65GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0060612; P:adipose tissue development; IGI:MGI.::GO:0045444; P:fat cell differentiation; IGI:MGI.::GO:0003151; P:outflow tract morphogenesis; IMP:MGI.::GO:0032915; P:positive regulation of transforming growth factor beta2 production; IMP:MGI.::GO:0006970; P:response to osmotic stress; ISS:UniProtKB.
34Q00969    487   ATF2_RAT Cyclic AMP-dependent transcription f...490.58     34.7     35     65GO:0005634; C:nucleus; IDA:RGD.
GO:0035497; F:cAMP response element binding; IDA:RGD.::GO:0046982; F:protein heterodimerization activity; IPI:RGD.::GO:0043565; F:sequence-specific DNA binding; IDA:RGD.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006970; P:response to osmotic stress; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
35P15336    505   ATF2_HUMAN Cyclic AMP-dependent transcription...490.63     34.7     35     65GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0035497; F:cAMP response element binding; IDA:BHF-UCL.::GO:0008140; F:cAMP response element binding protein binding; IDA:BHF-UCL.::GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.::GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IDA:BHF-UCL.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IC:BHF-UCL.::GO:0001076; F:RNA polymerase II transcription factor binding transcription factor activity; IC:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:Reactome.::GO:0006970; P:response to osmotic stress; IDA:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
36Q9MA75    341   VIP1_ARATH Transcription factor VIP1 OS=Arabi...361.2     33.5     44     69GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IMP:UniProtKB.
GO:0051019; F:mitogen-activated protein kinase binding; IPI:UniProtKB.::GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IDA:TAIR.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:TAIR.
GO:0009970; P:cellular response to sulfate starvation; IMP:TAIR.::GO:0006952; P:defense response; IEA:UniProtKB-KW.::GO:0009294; P:DNA mediated transformation; IDA:TAIR.::GO:0045596; P:negative regulation of cell differentiation; IDA:UniProtKB.::GO:0051170; P:nuclear import; IDA:TAIR.::GO:0080134; P:regulation of response to stress; IDA:TAIR.::GO:0008272; P:sulfate transport; IMP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
37A2C1Z5    291   RSMA_PROM1 Ribosomal RNA small subunit methyl...781.3     33.5     29     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0052908; F:16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0000179; F:rRNA (adenine-N6,N6-)-dimethyltransferase activity; IEA:InterPro.
38Q6ZDF3    318   TRAB1_ORYSJ bZIP transcription factor TRAB1 O...831.4     33.5     24     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0009738; P:abscisic acid mediated signaling pathway; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
39Q46L58    291   RSMA_PROMT Ribosomal RNA small subunit methyl...781.5     33.5     29     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0052908; F:16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0000179; F:rRNA (adenine-N6,N6-)-dimethyltransferase activity; IEA:InterPro.
40Q9C5Q2    262   AI5L3_ARATH ABSCISIC ACID-INSENSITIVE 5-like ...512     32.7     39     63GO:0005634; C:nucleus; IDA:TAIR.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:TAIR.
GO:0009738; P:abscisic acid mediated signaling pathway; TAS:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
41Q6S4P4    329   RF2B_ORYSJ Transcription factor RF2b OS=Oryza...352     33.1     43     71GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
42Q08CW8    428   CR3L4_XENTR Cyclic AMP-responsive element-bin...722.2     33.1     26     53GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
43P14233    242   TGA1B_TOBAC TGACG-sequence-specific DNA-bindi...472.2     32.7     32     68GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
44Q8R0S1    413   ATF7_MOUSE Cyclic AMP-dependent transcription...842.4     32.7     31     51GO:0034399; C:nuclear periphery; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
45P14907    823   NSP1_YEAST Nucleoporin NSP1 OS=Saccharomyces ...712.5     33.1     28     48GO:0055125; C:Nic96 complex; IDA:SGD.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0055126; C:Nup82 complex; IDA:SGD.
GO:0005543; F:phospholipid binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0017056; F:structural constituent of nuclear pore; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0097064; P:ncRNA export from nucleus; IMP:SGD.::GO:0016973; P:poly(A)+ mRNA export from nucleus; IGI:SGD.::GO:0006606; P:protein import into nucleus; IMP:SGD.::GO:0000055; P:ribosomal large subunit export from nucleus; IMP:SGD.::GO:0000056; P:ribosomal small subunit export from nucleus; IMP:SGD.::GO:0006409; P:tRNA export from nucleus; IMP:SGD.
46Q99941    703   ATF6B_HUMAN Cyclic AMP-dependent transcriptio...302.7     32.7     47     77GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; TAS:ProtInc.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; TAS:ProtInc.
47Q5R9C9    483   ATF7_PONAB Cyclic AMP-dependent transcription...1142.7     32.7     29     48GO:0034399; C:nuclear periphery; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
48Q9M7Q3    454   AI5L6_ARATH ABSCISIC ACID-INSENSITIVE 5-like ...492.8     32.7     33     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0009738; P:abscisic acid mediated signaling pathway; IMP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.::GO:0009414; P:response to water deprivation; IEP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
49P17544    494   ATF7_HUMAN Cyclic AMP-dependent transcription...1143.2     32.7     29     48GO:0005737; C:cytoplasm; IDA:HPA.::GO:0034399; C:nuclear periphery; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.
GO:0051019; F:mitogen-activated protein kinase binding; IDA:UniProtKB.::GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.::GO:0008134; F:transcription factor binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
50O35451    699   ATF6B_MOUSE Cyclic AMP-dependent transcriptio...303.3     32.7     47     77GO:0000794; C:condensed nuclear chromosome; ISS:UniProtKB.::GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; ISS:UniProtKB.::GO:0016363; C:nuclear matrix; ISS:UniProtKB.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0016458; P:gene silencing; ISS:UniProtKB.::GO:0007076; P:mitotic chromosome condensation; ISS:UniProtKB.::GO:0045749; P:negative regulation of S phase of mitotic cell cycle; ISS:UniProtKB.::GO:0045014; P:negative regulation of transcription by glucose; ISS:UniProtKB.::GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
51Q502F0    428   CR3LA_DANRE Cyclic AMP-responsive element-bin...483.4     32.3     33     65GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
52Q1LYG4    428   CR3LB_DANRE Cyclic AMP-responsive element-bin...483.5     32.3     33     65GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
53P18850    670   ATF6A_HUMAN Cyclic AMP-dependent transcriptio...386.4     31.6     45     71GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005635; C:nuclear envelope; TAS:ProtInc.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0006990; P:positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response; TAS:ProtInc.::GO:0006457; P:protein folding; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
54Q6NW59    339   ATF4_DANRE Cyclic AMP-dependent transcription...486.5     31.6     29     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
55Q54Q90    530   BZPL_DICDI Probable basic-leucine zipper tran...366.7     31.6     42     69GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
56Q68EL6    462   NFIL3_DANRE Nuclear factor interleukin-3-regu...757.4     31.2     39     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007623; P:circadian rhythm; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
57Q54Y73    834   BZPD_DICDI Probable basic-leucine zipper tran...387.9     31.6     29     71GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
58Q69IL4    380   RF2A_ORYSJ Transcription factor RF2a OS=Oryza...358.7     31.2     40     69GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
59Q9D2A5    370   CR3L4_MOUSE Cyclic AMP-responsive element-bin...708.8     31.2     29     56GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0002079; C:inner acrosomal membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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