Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFL029C
Length:
368
Number of sequences:
5887
Description:
YFL029C CAK1 SGDID:S000001865, Chr VI from 79161-78055, Genome Release 64-1-1, reverse complement, Verified ORF, "Cyclin-dependent kinase-activating kinase required for passage through the cell cycle, phosphorylates and activates Cdc28p; nucleotide-binding pocket differs significantly from those of most other protein kinases"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
301Q54Y06    636   Y8487_DICDI Probable cyclin-dependent serine/...2280.000000003     62     25     43
GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
302Q90327    427   MK08A_CYPCA Mitogen-activated protein kinase ...1120.000000003     61.6     33     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
303O42781    351   MAPK2_PNECA Mitogen-activated protein kinase ...1020.000000003     61.2     31     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.
GO:0000751; P:cell cycle arrest in response to pheromone; NAS:UniProtKB.
304Q4PKS0    200   HOG1_GIBIN Mitogen-activated protein kinase H...1050.000000003     59.7     31     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
305A5PKJ4    781   MK07_BOVIN Mitogen-activated protein kinase 7...1050.000000003     62     29     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
306Q54QB1    369   ERK2_DICDI Extracellular signal-regulated kin...990.000000003     61.2     32     60GO:0005829; C:cytosol; TAS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007190; P:activation of adenylate cyclase activity; TAS:dictyBase.::GO:0031152; P:aggregation involved in sorocarp development; TAS:dictyBase.::GO:0019933; P:cAMP-mediated signaling; IDA:dictyBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051344; P:negative regulation of cyclic-nucleotide phosphodiesterase activity; IGI:dictyBase.
307Q14AX6    1484   CDK12_MOUSE Cyclin-dependent kinase 12 OS=Mus...1070.000000003     62.4     36     57GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:HGNC.::GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB.::GO:0008380; P:RNA splicing; ISS:UniProtKB.
308D2H526    1491   CDK12_AILME Cyclin-dependent kinase 12 OS=Ail...1070.000000003     62.4     36     57GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; ISS:UniProtKB.::GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB.::GO:0008380; P:RNA splicing; ISS:UniProtKB.
309P79996    382   MK09_CHICK Mitogen-activated protein kinase 9...1570.000000004     61.2     29     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0035419; P:activation of MAPK activity involved in innate immune response; TAS:Reactome.::GO:0009790; P:embryo development; IDA:UniProtKB.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0035681; P:toll-like receptor 15 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0035682; P:toll-like receptor 21 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.::GO:0034154; P:toll-like receptor 7 signaling pathway; TAS:Reactome.
310Q0D4J7    339   SAPK2_ORYSJ Serine/threonine-protein kinase S...950.000000004     61.2     39     57
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.
311Q9WVS8    806   MK07_MOUSE Mitogen-activated protein kinase 7...1050.000000004     62     29     53GO:0005829; C:cytosol; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006915; P:apoptotic process; IMP:MGI.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051534; P:negative regulation of NFAT protein import into nucleus; IMP:MGI.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI.::GO:0045765; P:regulation of angiogenesis; IMP:MGI.
312O93982    431   HOG1_ZYGRC Mitogen-activated protein kinase H...1020.000000004     61.6     34     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
313P0C865    806   MK07_RAT Mitogen-activated protein kinase 7 O...1050.000000004     62     29     53GO:0005634; C:nucleus; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0004707; F:MAP kinase activity; IDA:RGD.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0070375; P:ERK5 cascade; IMP:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.
314Q92207    377   HOG1_CANAL Mitogen-activated protein kinase H...1050.000000004     61.2     32     54GO:0005737; C:cytoplasm; IDA:CGD.::GO:0005634; C:nucleus; IDA:CGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; ISS:CGD.
GO:0071276; P:cellular response to cadmium ion; IMP:CGD.::GO:0034605; P:cellular response to heat; IMP:CGD.::GO:0034599; P:cellular response to oxidative stress; IMP:CGD.::GO:0001410; P:chlamydospore formation; IMP:CGD.::GO:0031505; P:fungal-type cell wall organization; IMP:CGD.::GO:0030448; P:hyphal growth; IMP:CGD.::GO:0006973; P:intracellular accumulation of glycerol; IMP:CGD.::GO:0009405; P:pathogenesis; IMP:CGD.::GO:0046173; P:polyol biosynthetic process; IMP:CGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0051403; P:stress-activated MAPK cascade; IDA:CGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
315Q75V57    361   SAPK9_ORYSJ Serine/threonine-protein kinase S...950.000000004     61.2     38     57
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.
316A2QRF6    365   HOG1_ASPNC Mitogen-activated protein kinase h...1050.000000004     61.2     31     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
317O61267    476   LOK_DROME Ovarian-specific serine/threonine-p...1140.000000004     61.6     35     54GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB.
GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:FlyBase.::GO:0071480; P:cellular response to gamma radiation; IMP:BHF-UCL.::GO:0000077; P:DNA damage checkpoint; IDA:FlyBase.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IMP:BHF-UCL.::GO:0007281; P:germ cell development; IEP:UniProtKB.::GO:0035234; P:germ cell programmed cell death; IMP:FlyBase.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0072332; P:signal transduction by p53 class mediator resulting in induction of apoptosis; IGI:BHF-UCL.
318Q13164    816   MK07_HUMAN Mitogen-activated protein kinase 7...1050.000000004     62     29     53GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0071499; P:cellular response to laminar fluid shear stress; TAS:BHF-UCL.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IGI:BHF-UCL.::GO:0034115; P:negative regulation of heterotypic cell-cell adhesion; IGI:BHF-UCL.::GO:0050728; P:negative regulation of inflammatory response; TAS:BHF-UCL.::GO:0060761; P:negative regulation of response to cytokine stimulus; IGI:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0051247; P:positive regulation of protein metabolic process; IGI:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:BHF-UCL.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
319Q0D0P5    364   HOG1_ASPTN Mitogen-activated protein kinase h...1050.000000004     61.2     31     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
320Q02066    332   AAIP_WHEAT Abscisic acid-inducible protein ki...1000.000000004     60.8     36     56
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
321Q1RLU9    418   CDK15_DANRE Cyclin-dependent kinase 15 OS=Dan...1530.000000004     61.2     24     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
322Q4PNJ1    207   HOG1_FUSCU Mitogen-activated protein kinase H...1050.000000004     59.3     31     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
323Q12126    335   CRK1_SCHPO Serine/threonine-protein kinase cr...1450.000000004     60.8     27     44GO:0005829; C:cytosol; IDA:PomBase.::GO:0005675; C:holo TFIIH complex; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019912; F:cyclin-dependent protein kinase activating kinase activity; IGI:PomBase.::GO:0004693; F:cyclin-dependent protein kinase activity; NAS:PomBase.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:PomBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0070817; P:P-TEFb-cap methyltransferase complex localization; IMP:PomBase.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IMP:PomBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IGI:PomBase.::GO:0034243; P:regulation of transcription elongation from RNA polymerase II promoter; IMP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
324A3LN91    385   HOG1_PICST Mitogen-activated protein kinase H...1050.000000005     61.2     32     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
325Q1DUU8    364   HOG1_COCIM Mitogen-activated protein kinase H...1020.000000005     60.8     33     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
326Q4V7Q6    468   ULK3_XENLA Serine/threonine-protein kinase UL...990.000000005     61.2     34     54GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0045879; P:negative regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
327Q0U4L8    355   HOG1_PHANO Mitogen-activated protein kinase H...1050.000000005     60.8     32     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
328Q16644    382   MAPK3_HUMAN MAP kinase-activated protein kina...1150.000000005     60.8     33     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0045087; P:innate immune response; TAS:Reactome.::GO:0044351; P:macropinocytosis; ISS:UniProtKB.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0032496; P:response to lipopolysaccharide; ISS:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
329O59854    407   HOG1_ZYGRO Mitogen-activated protein kinase H...1020.000000005     61.2     34     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
330P39745    444   SUR1_CAEEL Mitogen-activated protein kinase m...1070.000000005     61.2     31     56GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IMP:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0051729; P:germline cell cycle switching, mitotic to meiotic cell cycle; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:WormBase.::GO:0007265; P:Ras protein signal transduction; IGI:WormBase.::GO:0040025; P:vulval development; IMP:UniProtKB.
331O59853    420   HOG2_ZYGRO Mitogen-activated protein kinase H...1050.000000005     61.2     33     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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