Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFL029C
Length:
368
Number of sequences:
5887
Description:
YFL029C CAK1 SGDID:S000001865, Chr VI from 79161-78055, Genome Release 64-1-1, reverse complement, Verified ORF, "Cyclin-dependent kinase-activating kinase required for passage through the cell cycle, phosphorylates and activates Cdc28p; nucleotide-binding pocket differs significantly from those of most other protein kinases"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
271Q9HGN1    1576   GCN2_SCHPO Serine/threonine-protein kinase gc...1110.000000002     63.2     35     57
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004694; F:eukaryotic translation initiation factor 2alpha kinase activity; IDA:PomBase.::GO:0042803; F:protein homodimerization activity; ISS:PomBase.::GO:0000049; F:tRNA binding; IEA:InterPro.
GO:0002183; P:cytoplasmic translational initiation; NAS:PomBase.::GO:0031575; P:mitotic cell cycle G1/S transition checkpoint; IMP:PomBase.::GO:0071263; P:negative regulation of translational initiation in response to starvation; TAS:PomBase.::GO:0043561; P:regulation of translational initiation in response to osmotic stress; IGI:PomBase.
272Q84UI5    398   MPK1_ORYSJ Mitogen-activated protein kinase 1...1180.000000002     62.4     30     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
273Q8SR90    309   Y8H9_ENCCU Probable cell division protein kin...1540.000000002     62     31     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
274Q9TXJ0    348   CMK1_CAEEL Calcium/calmodulin-dependent prote...1010.000000002     62     37     54GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IDA:WormBase.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:WormBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0048812; P:neuron projection morphogenesis; IMP:WormBase.::GO:0032793; P:positive regulation of CREB transcription factor activity; IDA:WormBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:WormBase.::GO:0046777; P:protein autophosphorylation; IDA:WormBase.::GO:0045664; P:regulation of neuron differentiation; IMP:WormBase.::GO:0040040; P:thermosensory behavior; IMP:WormBase.
275Q6Z437    370   MPK3_ORYSJ Mitogen-activated protein kinase 3...1120.000000002     62.4     30     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
276Q39024    376   MPK4_ARATH Mitogen-activated protein kinase 4...1180.000000002     62     29     51GO:0005829; C:cytosol; IDA:TAIR.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0043622; P:cortical microtubule organization; IMP:UniProtKB.::GO:0006972; P:hyperosmotic response; IMP:TAIR.::GO:0042539; P:hypotonic salinity response; IDA:TAIR.::GO:0009868; P:jasmonic acid and ethylene-dependent systemic resistance, jasmonic acid mediated signaling pathway; TAS:TAIR.::GO:0007112; P:male meiosis cytokinesis; IMP:TAIR.::GO:0009555; P:pollen development; IMP:TAIR.::GO:0009737; P:response to abscisic acid stimulus; IEP:TAIR.::GO:0009409; P:response to cold; IDA:TAIR.::GO:0009620; P:response to fungus; IMP:TAIR.::GO:0009862; P:systemic acquired resistance, salicylic acid mediated signaling pathway; IMP:TAIR.
277P43068    501   MKC1_CANAX Mitogen-activated protein kinase M...1020.000000002     62.4     30     56
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
278Q4I5U9    473   BUR1_GIBZE Serine/threonine-protein kinase BU...1050.000000002     62.4     29     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
279Q40517    372   NTF3_TOBAC Mitogen-activated protein kinase h...1180.000000002     62     30     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
280Q6CR51    593   SSN3_KLULA Serine/threonine-protein kinase SS...1170.000000002     62.8     32     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
281Q9Y6R4    1608   M3K4_HUMAN Mitogen-activated protein kinase k...1510.000000002     63.2     31     48GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; TAS:ProtInc.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007254; P:JNK cascade; TAS:ProtInc.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB.
282O75385    1050   ULK1_HUMAN Serine/threonine-protein kinase UL...1070.000000002     62.8     34     52GO:0005776; C:autophagic vacuole; IDA:UniProtKB.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0034045; C:pre-autophagosomal structure membrane; IDA:UniProtKB.::GO:0070969; C:ULK1-ATG13-FIP200 complex; IPI:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0032403; F:protein complex binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0008104; P:protein localization; IMP:UniProtKB.
283Q9UV50    387   HOG1_DEBHA Mitogen-activated protein kinase H...1020.000000002     62     34     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
284Q40353    371   MMK2_MEDSA Mitogen-activated protein kinase h...1180.000000002     62     29     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
285Q10452    387   GSK3_SCHPO Protein kinase gsk3 OS=Schizosacch...2260.000000002     62     24     44GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:PomBase.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IDA:UniProtKB.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051984; P:positive regulation of chromosome segregation; IMP:UniProtKB.::GO:0071775; P:regulation of cell cycle cytokinesis; IGI:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.
286A2YNT8    339   SAPK2_ORYSI Serine/threonine-protein kinase S...950.000000002     61.6     39     57
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.
287Q75LR7    342   SAPK1_ORYSJ Serine/threonine-protein kinase S...1000.000000003     61.6     37     56
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.
288Q9DGD9    384   MK08_DANRE Mitogen-activated protein kinase 8...1560.000000003     62     31     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0048263; P:determination of dorsal identity; IMP:MGI.::GO:0007254; P:JNK cascade; ISS:UniProtKB.
289Q9NYV4    1490   CDK12_HUMAN Cyclin-dependent kinase 12 OS=Hom...1070.000000003     62.8     36     57GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0016607; C:nuclear speck; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IMP:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:HGNC.::GO:0043405; P:regulation of MAP kinase activity; IMP:UniProtKB.::GO:0008380; P:RNA splicing; ISS:UniProtKB.
290P34208    496   CHK1_SCHPO Serine/threonine-protein kinase ch...1760.000000003     62     30     46GO:0005829; C:cytosol; IDA:PomBase.::GO:0005654; C:nucleoplasm; TAS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:PomBase.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000077; P:DNA damage checkpoint; IGI:PomBase.
291Q10N20    369   MPK5_ORYSJ Mitogen-activated protein kinase 5...1180.000000003     61.6     31     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006952; P:defense response; IEA:UniProtKB-KW.
292A2XFC8    369   MPK5_ORYSI Mitogen-activated protein kinase 5...1180.000000003     61.6     31     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006952; P:defense response; IEA:UniProtKB-KW.
293Q75H77    362   SAPKA_ORYSJ Serine/threonine-protein kinase S...1000.000000003     61.6     36     56
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.
294Q3MJK5    1484   CDK12_RAT Cyclin-dependent kinase 12 OS=Rattu...1070.000000003     62.4     36     57GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; IDA:UniProtKB.::GO:0016607; C:nuclear speck; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030332; F:cyclin binding; IPI:UniProtKB.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; ISS:UniProtKB.::GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB.::GO:0008380; P:RNA splicing; IMP:UniProtKB.
295Q8SW92    308   KIN28_ENCCU Probable serine/threonine-protein...1540.000000003     61.2     28     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
296P46551    730   CDK12_CAEEL Cyclin-dependent kinase 12 OS=Cae...1550.000000003     62.4     26     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.
297Q4PC06    358   HOG1_USTMA Mitogen-activated protein kinase H...1050.000000003     61.6     32     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
298P0CP66    366   CPK1_CRYNJ Mitogen-activated protein kinase C...1020.000000003     61.6     30     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
299P0CP67    366   CPK1_CRYNB Mitogen-activated protein kinase C...1020.000000003     61.6     30     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
300Q5Z859    369   MPK4_ORYSJ Mitogen-activated protein kinase 4...1120.000000003     61.6     32     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
301Q54Y06    636   Y8487_DICDI Probable cyclin-dependent serine/...2280.000000003     62     25     43
GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
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