Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFL018C
Length:
499
Number of sequences:
5887
Description:
YFL018C LPD1 SGDID:S000001876, Chr VI from 103127-101628, Genome Release 64-1-1, reverse complement, Verified ORF, "Dihydrolipoamide dehydrogenase, the lipoamide dehydrogenase component (E3) of the pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase multi-enzyme complexes"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
211Q9MYY8    499   TRXR1_PIG Thioredoxin reductase 1, cytoplasmi...4396e-35     140     26     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
212Q86VQ6    682   TRXR3_HUMAN Thioredoxin reductase 3 OS=Homo s...4368e-35     141     26     46GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; NAS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045454; P:cell redox homeostasis; NAS:UniProtKB.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
213Q5NVA2    499   TRXR1_PONAB Thioredoxin reductase 1, cytoplas...4391e-34     139     26     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
214O62768    499   TRXR1_BOVIN Thioredoxin reductase 1, cytoplas...4393e-34     138     25     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
215O89049    499   TRXR1_RAT Thioredoxin reductase 1, cytoplasmi...4373e-34     138     25     46GO:0005829; C:cytosol; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0045340; F:mercury ion binding; IDA:RGD.::GO:0016174; F:NAD(P)H oxidase activity; IDA:RGD.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0033797; F:selenate reductase activity; IDA:RGD.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:RGD.
GO:0042537; P:benzene-containing compound metabolic process; IDA:RGD.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0071280; P:cellular response to copper ion; IEP:RGD.::GO:0071455; P:cellular response to hyperoxia; IEP:RGD.::GO:0006749; P:glutathione metabolic process; IEP:RGD.::GO:0070276; P:halogen metabolic process; IEP:RGD.::GO:0042744; P:hydrogen peroxide catabolic process; IMP:RGD.::GO:0042191; P:methylmercury metabolic process; IEP:RGD.::GO:0070995; P:NADPH oxidation; IDA:RGD.::GO:0001890; P:placenta development; IEP:RGD.::GO:0010942; P:positive regulation of cell death; IMP:RGD.::GO:0051262; P:protein tetramerization; IDA:RGD.::GO:0048678; P:response to axon injury; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0010269; P:response to selenium ion; IEP:RGD.::GO:0016259; P:selenocysteine metabolic process; IMP:RGD.
216Q9JMH6    613   TRXR1_MOUSE Thioredoxin reductase 1, cytoplas...4396e-34     138     26     46GO:0005829; C:cytosol; IDA:MGI.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:MGI.
GO:0008283; P:cell proliferation; IMP:MGI.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0001707; P:mesoderm formation; IMP:MGI.
217P39040    491   TYTR_CRIFA Trypanothione reductase OS=Crithid...4939e-34     136     26     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015042; F:trypanothione-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
218Q16881    649   TRXR1_HUMAN Thioredoxin reductase 1, cytoplas...4391e-33     137     26     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; EXP:Reactome.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.::GO:0007165; P:signal transduction; NAS:ProtInc.::GO:0006810; P:transport; IEA:UniProtKB-KW.
219O07927    459   MTR_MYCTU Mycothione reductase OS=Mycobacteri...4823e-33     134     26     46GO:0005829; C:cytosol; TAS:Reactome.
GO:0050660; F:flavin adenine dinucleotide binding; IDA:MTBBASE.::GO:0050627; F:mycothione reductase activity; IDA:MTBBASE.::GO:0070402; F:NADPH binding; IDA:MTBBASE.::GO:0042803; F:protein homodimerization activity; IPI:MTBBASE.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0040007; P:growth; IMP:MTBBASE.::GO:0010126; P:mycothiol metabolic process; TAS:Reactome.
220Q25861    541   TRXR_PLAF5 Thioredoxin reductase OS=Plasmodiu...4884e-33     135     26     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
221Q6BPI1    490   GSHR_DEBHA Glutathione reductase OS=0083 / IG...4855e-33     134     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro.
222P91938    596   TRXR1_DROME Thioredoxin reductase 1, mitochon...4961e-32     134     25     45GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005739; C:mitochondrion; IDA:UniProtKB.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IMP:FlyBase.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:FlyBase.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:UniProtKB.
GO:0045454; P:cell redox homeostasis; IMP:UniProtKB.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0001666; P:response to hypoxia; IMP:FlyBase.
223P61076    617   TRXR2_PLAF7 Thioredoxin reductase 2 OS=Plasmo...4881e-32     134     26     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
224P70619    424   GSHR_RAT Glutathione reductase OS=Rattus norv...4361e-32     132     27     46GO:0005829; C:cytosol; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0050660; F:flavin adenine dinucleotide binding; IDA:RGD.::GO:0043295; F:glutathione binding; IDA:RGD.::GO:0004362; F:glutathione-disulfide reductase activity; IDA:RGD.::GO:0050661; F:NADP binding; IDA:RGD.::GO:0042803; F:protein homodimerization activity; IDA:RGD.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IDA:RGD.::GO:0007283; P:spermatogenesis; IMP:RGD.
225P28593    492   TYTR_TRYCR Trypanothione reductase OS=Trypano...5075e-32     131     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015042; F:trypanothione-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
226Q9VNT5    516   TRXR2_DROME Thioredoxin reductase 2, mitochon...5083e-31     129     26     44GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:FlyBase.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
227P30635    503   GSHR_CAEEL Probable glutathione reductase 2 O...4972e-30     126     26     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:WormBase.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
228P39050    491   TYTR_LEIDO Trypanothione reductase OS=Leishma...5027e-30     125     25     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015042; F:trypanothione-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
229Q17745    667   TRXR1_CAEEL Thioredoxin reductase 1 OS=Caenor...4871e-29     126     25     46GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0015036; F:disulfide oxidoreductase activity; NAS:UniProtKB.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; ISS:UniProtKB.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
230O15770    500   GSHR_PLAF7 Glutathione reductase OS=Plasmodiu...4832e-29     124     26     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
231Q94655    500   GSHR_PLAFK Glutathione reductase OS=Plasmodiu...4843e-29     123     26     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
232B9A1H3    495   TRXR1_EMIHU Thioredoxin reductase SEP1 OS=Emi...4916e-26     114     26     44GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
233Q56839    523   XECC_XANP2 2-oxopropyl-CoM reductase, carboxy...4786e-23     105     22     43GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0050628; F:2-oxopropyl-CoM reductase (carboxylating) activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
234P08662    460   MERA_SERMA Mercuric reductase OS=Serratia mar...1430.00000002     59.7     28     46GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016152; F:mercury (II) reductase activity; IEA:EC.::GO:0045340; F:mercury ion binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0016668; F:oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0050787; P:detoxification of mercury ion; IEA:InterPro.::GO:0030001; P:metal ion transport; IEA:InterPro.
235P80647    53   DLDH_HYMDI Dihydrolipoyl dehydrogenase OS=Hym...475e-16     77     74     81GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0004148; F:dihydrolipoyl dehydrogenase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
236P08655    180   YMER_STAAU Uncharacterized 19.7 kDa protein i...1310.000000000009     67.8     30     56GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
237P71317    150   STHA_PECCC Soluble pyridine nucleotide transh...1470.00000000003     65.9     29     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
238P42435    805   NASD_BACSU Nitrite reductase [NAD(P)H] OS=Bac...2620.0000000002     67.4     27     45
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0008942; F:nitrite reductase [NAD(P)H activity; IEA:EC.
GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.]
239P66011    311   TRXB_STAAW Thioredoxin reductase OS=Staphyloc...3300.0000000006     63.9     25     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC.
GO:0019430; P:removal of superoxide radicals; IEA:InterPro.
240Q6GB66    311   TRXB_STAAS Thioredoxin reductase OS=Staphyloc...3300.0000000006     63.9     25     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC.
GO:0019430; P:removal of superoxide radicals; IEA:InterPro.
241P99101    311   TRXB_STAAN Thioredoxin reductase OS=Staphyloc...3300.0000000006     63.9     25     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC.
GO:0019430; P:removal of superoxide radicals; IEA:InterPro.
records
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