rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | P61964 | 334 | WDR5_HUMAN WD repeat-containing protein 5 OS=... | 230 | 0.000001 | 54.7 | 26 | 44 | GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:BHF-UCL.::GO:0071339; C:MLL1 complex; IDA:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.::GO:0051568; P:histone H3-K4 methylation; IDA:UniProtKB.::GO:0043984; P:histone H4-K16 acetylation; IDA:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 62 | Q2KIG2 | 334 | WDR5_BOVIN WD repeat-containing protein 5 OS=... | 115 | 0.96 | 36.2 | 23 | 42 | GO:0000123; C:histone acetyltransferase complex; ISS:UniProtKB.::GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; ISS:UniProtKB. | | | | | | | | | | GO:0051568; P:histone H3-K4 methylation; ISS:UniProtKB.::GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 63 | A7S338 | 409 | LIS1_NEMVE Lissencephaly-1 homolog OS=Nematos... | 146 | 0.0003 | 47.8 | 25 | 45 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 64 | Q9PTR5 | 410 | LIS1_CHICK Lissencephaly-1 homolog OS=Gallus ... | 146 | 0.0004 | 47.4 | 26 | 43 | | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 65 | Q0U2T3 | 681 | MDV1_PHANO Mitochondrial division protein 1 O... | 355 | 0.0000001 | 59.3 | 21 | 37 | GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 66 | P25382 | 515 | NLE1_YEAST Ribosome assembly protein 4 OS=Sac... | 238 | 0.000006 | 53.1 | 26 | 42 | GO:0005730; C:nucleolus; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0000027; P:ribosomal large subunit assembly; IMP:SGD. | 67 | Q5AXW3 | 654 | MDV1_EMENI Mitochondrial division protein 1 O... | 184 | 0.0003 | 47.8 | 23 | 38 | GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 68 | Q01277 | 650 | SCONB_NEUCR Probable E3 ubiquitin ligase comp... | 100 | 0.000001 | 55.8 | 32 | 52 | | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 69 | P38129 | 798 | TAF5_YEAST Transcription initiation factor TF... | 193 | 0.88 | 37 | 22 | 44 | GO:0000124; C:SAGA complex; IDA:SGD.::GO:0046695; C:SLIK (SAGA-like) complex; IDA:SGD.::GO:0005669; C:transcription factor TFIID complex; IDA:SGD. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:SGD.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0032947; F:protein complex scaffold; IMP:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD. | | | | | | | | | | GO:0016573; P:histone acetylation; IDA:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0051123; P:RNA polymerase II transcriptional preinitiation complex assembly; IC:SGD. | 70 | A1DDL6 | 658 | MDV1_NEOFI Mitochondrial division protein 1 O... | 123 | 0.002 | 45.4 | 28 | 51 | GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 71 | A2R3Z3 | 657 | MDV1_ASPNC Mitochondrial division protein 1 O... | 123 | 0.009 | 43.1 | 28 | 50 | GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 72 | O74855 | 502 | NLE1_SCHPO Ribosome assembly protein C18.05c ... | 168 | 0.0000003 | 57.8 | 26 | 42 | GO:0005730; C:nucleolus; ISS:PomBase.::GO:0043234; C:protein complex; NAS:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0042254; P:ribosome biogenesis; ISS:PomBase. | 73 | Q2UFN8 | 705 | SCONB_ASPOR Probable E3 ubiquitin ligase comp... | 79 | 0.027 | 41.6 | 30 | 51 | | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 74 | P63004 | 410 | LIS1_RAT Platelet-activating factor acetylhyd... | 146 | 0.0002 | 48.1 | 27 | 43 | GO:0033267; C:axon part; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0030426; C:growth cone; IDA:RGD.::GO:0005871; C:kinesin complex; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0042598; C:vesicular fraction; IDA:RGD. | | | | | | | | | | GO:0045505; F:dynein intermediate chain binding; IDA:RGD.::GO:0047179; F:platelet-activating factor acetyltransferase activity; TAS:RGD. | | | | | | | | | | GO:0021895; P:cerebral cortex neuron differentiation; IMP:RGD.::GO:0051660; P:establishment of centrosome localization; IMP:RGD.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010977; P:negative regulation of neuron projection development; IMP:RGD.::GO:0001764; P:neuron migration; IMP:RGD.::GO:0007097; P:nuclear migration; IMP:RGD.::GO:0045773; P:positive regulation of axon extension; IMP:RGD.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:RGD.::GO:0017145; P:stem cell division; IMP:RGD. | 75 | P63005 | 410 | LIS1_MOUSE Platelet-activating factor acetylh... | 146 | 0.0002 | 48.1 | 27 | 43 | GO:0005813; C:centrosome; IDA:MGI.::GO:0031512; C:motile primary cilium; IDA:MGI.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:MGI. | | | | | | | | | | GO:0008017; F:microtubule binding; IDA:MGI.::GO:0051219; F:phosphoprotein binding; IPI:MGI.::GO:0042803; F:protein homodimerization activity; IPI:MGI. | | | | | | | | | | GO:0001675; P:acrosome assembly; IMP:MGI.::GO:0030036; P:actin cytoskeleton organization; IMP:MGI.::GO:0008344; P:adult locomotory behavior; IMP:MGI.::GO:0021766; P:hippocampus development; IMP:MGI.::GO:0021819; P:layer formation in cerebral cortex; IGI:MGI.::GO:0007611; P:learning or memory; IMP:MGI.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007405; P:neuroblast proliferation; IMP:MGI.::GO:0050885; P:neuromuscular process controlling balance; IMP:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0051081; P:nuclear envelope disassembly; IMP:MGI.::GO:0032319; P:regulation of Rho GTPase activity; IMP:MGI.::GO:0008090; P:retrograde axon cargo transport; IDA:MGI.::GO:0007268; P:synaptic transmission; IMP:MGI. | 76 | B0LSW3 | 410 | LIS1_FELCA Platelet-activating factor acetylh... | 146 | 0.0002 | 48.1 | 27 | 43 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 77 | D3TLL6 | 411 | LIS1_GLOMM Lissencephaly-1 homolog OS=Glossin... | 147 | 0.007 | 43.1 | 27 | 41 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 78 | B8NGT5 | 706 | SCONB_ASPFN Probable E3 ubiquitin ligase comp... | 79 | 0.028 | 41.6 | 30 | 51 | | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 79 | P43034 | 410 | LIS1_HUMAN Platelet-activating factor acetylh... | 146 | 0.0002 | 48.1 | 27 | 43 | GO:0000235; C:astral microtubule; IDA:UniProtKB.::GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; ISS:BHF-UCL.::GO:0000776; C:kinetochore; IDA:UniProtKB.::GO:0031512; C:motile primary cilium; ISS:BHF-UCL.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:BHF-UCL. | | | | | | | | | | GO:0034452; F:dynactin binding; ISS:BHF-UCL.::GO:0008201; F:heparin binding; ISS:BHF-UCL.::GO:0008017; F:microtubule binding; ISS:BHF-UCL.::GO:0043274; F:phospholipase binding; ISS:BHF-UCL.::GO:0051219; F:phosphoprotein binding; ISS:BHF-UCL.::GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL. | | | | | | | | | | GO:0001675; P:acrosome assembly; ISS:BHF-UCL.::GO:0030036; P:actin cytoskeleton organization; ISS:BHF-UCL.::GO:0008344; P:adult locomotory behavior; IMP:BHF-UCL.::GO:0048854; P:brain morphogenesis; IMP:BHF-UCL.::GO:0021540; P:corpus callosum morphogenesis; IMP:BHF-UCL.::GO:0000132; P:establishment of mitotic spindle orientation; IMP:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0021766; P:hippocampus development; ISS:BHF-UCL.::GO:0021819; P:layer formation in cerebral cortex; ISS:BHF-UCL.::GO:0007611; P:learning or memory; ISS:BHF-UCL.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0031023; P:microtubule organizing center organization; IMP:UniProtKB.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0007405; P:neuroblast proliferation; ISS:BHF-UCL.::GO:0050885; P:neuromuscular process controlling balance; IMP:BHF-UCL.::GO:0001764; P:neuron migration; IMP:UniProtKB.::GO:0046469; P:platelet activating factor metabolic process; ISS:BHF-UCL.::GO:0032319; P:regulation of Rho GTPase activity; ISS:BHF-UCL.::GO:0008090; P:retrograde axon cargo transport; ISS:BHF-UCL.::GO:0007268; P:synaptic transmission; ISS:BHF-UCL.::GO:0047496; P:vesicle transport along microtubule; ISS:BHF-UCL. | 80 | A4RJV3 | 661 | MDV1_MAGO7 Mitochondrial division protein 1 O... | 339 | 0.000000001 | 65.9 | 22 | 39 | GO:0030015; C:CCR4-NOT core complex; ISS:PAMGO_MGG.::GO:0005741; C:mitochondrial outer membrane; ISS:PAMGO_MGG. | | | | | | | | | | GO:0051020; F:GTPase binding; ISS:PAMGO_MGG. | | | | | | | | | | GO:0000266; P:mitochondrial fission; ISS:PAMGO_MGG.::GO:0000002; P:mitochondrial genome maintenance; ISS:PAMGO_MGG.::GO:0006402; P:mRNA catabolic process; ISS:PAMGO_MGG.::GO:0006355; P:regulation of transcription, DNA-dependent; ISS:PAMGO_MGG.::GO:0006354; P:transcription elongation, DNA-dependent; ISS:PAMGO_MGG.::GO:0006352; P:transcription initiation, DNA-dependent; ISS:PAMGO_MGG. | 81 | P43033 | 410 | LIS1_BOVIN Platelet-activating factor acetylh... | 146 | 0.0002 | 47.8 | 27 | 43 | GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0034452; F:dynactin binding; IDA:BHF-UCL.::GO:0045502; F:dynein binding; IDA:BHF-UCL.::GO:0008201; F:heparin binding; IDA:BHF-UCL.::GO:0008017; F:microtubule binding; IDA:MGI.::GO:0043274; F:phospholipase binding; IDA:BHF-UCL. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0046469; P:platelet activating factor metabolic process; IDA:BHF-UCL.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 82 | P16649 | 713 | TUP1_YEAST General transcriptional corepresso... | 139 | 3.7 | 34.7 | 24 | 40 | GO:0017053; C:transcriptional repressor complex; IDA:SGD. | | | | | | | | | | GO:0042393; F:histone binding; IDA:SGD.::GO:0042826; F:histone deacetylase binding; IDA:SGD.::GO:0036033; F:mediator complex binding; IDA:SGD.::GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IDA:SGD.::GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; IDA:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD. | | | | | | | | | | GO:0043486; P:histone exchange; IMP:SGD.::GO:0035955; P:negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0001198; P:negative regulation of mating-type specific transcription from RNA polymerase II promoter; IMP:SGD.::GO:0000433; P:negative regulation of transcription from RNA polymerase II promoter by glucose; IMP:SGD.::GO:0007070; P:negative regulation of transcription from RNA polymerase II promoter during mitosis; IMP:SGD.::GO:0016584; P:nucleosome positioning; IDA:SGD.::GO:2000531; P:regulation of fatty acid biosynthetic process by regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:2001020; P:regulation of response to DNA damage stimulus; IMP:SGD.::GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; IMP:SGD.::GO:0061392; P:regulation of transcription from RNA polymerase II promoter in response to osmotic stress; IMP:SGD. | 83 | Q5REG7 | 410 | LIS1_PONAB Platelet-activating factor acetylh... | 146 | 0.0004 | 47.4 | 26 | 43 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 84 | B7FNU7 | 439 | LIS1_PHATC Lissencephaly-1 homolog OS=Phaeoda... | 52 | 0.94 | 36.6 | 37 | 60 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 85 | A1C7E4 | 700 | SCONB_ASPCL Probable E3 ubiquitin ligase comp... | 173 | 0.0000000009 | 65.9 | 28 | 43 | | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 86 | Q8HXX0 | 410 | LIS1_MACFA Platelet-activating factor acetylh... | 146 | 0.0005 | 47 | 26 | 43 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 87 | O43017 | 380 | SWD3_SCHPO Set1 complex component swd3 OS=Sch... | 244 | 3e-18 | 90.9 | 27 | 47 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.::GO:0048188; C:Set1C/COMPASS complex; IDA:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0006338; P:chromatin remodeling; IC:PomBase.::GO:0051568; P:histone H3-K4 methylation; IMP:PomBase. | 88 | A2QCU8 | 670 | SCONB_ASPNC Probable E3 ubiquitin ligase comp... | 173 | 0.000000005 | 63.5 | 26 | 42 | | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 89 | A7ETB3 | 667 | MDV1_SCLS1 Mitochondrial division protein 1 O... | 72 | 0.001 | 45.8 | 33 | 56 | GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 90 | Q9GL51 | 410 | LIS1_PIG Platelet-activating factor acetylhyd... | 146 | 0.0002 | 48.5 | 27 | 43 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 91 | Q7ZUV2 | 694 | KTNB1_DANRE Katanin p80 WD40-containing subun... | 306 | 0.000000000008 | 72.4 | 21 | 43 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. |