Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFL008W
Length:
1225
Number of sequences:
5887
Description:
YFL008W SMC1 SGDID:S000001886, Chr VI from 119429-123106, Genome Release 64-1-1, Verified ORF, "Subunit of the multiprotein cohesin complex, essential protein involved in chromosome segregation and in double-strand DNA break repair; SMC chromosomal ATPase family member, binds DNA with a preference for DNA with secondary structure"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q8IY18    1101   SMC5_HUMAN Structural maintenance of chromoso...830.077     41.2     28     49GO:0000781; C:chromosome, telomeric region; IDA:UniProtKB.::GO:0016605; C:PML body; IDA:UniProtKB.::GO:0030915; C:Smc5-Smc6 complex; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0090398; P:cellular senescence; IMP:UniProtKB.::GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0034184; P:positive regulation of maintenance of mitotic sister chromatid cohesion; IMP:UniProtKB.::GO:0045842; P:positive regulation of mitotic metaphase/anaphase transition; IMP:UniProtKB.::GO:0000722; P:telomere maintenance via recombination; IMP:UniProtKB.
92Q5ZJY5    1065   SMC5_CHICK Structural maintenance of chromoso...1210.002     45.8     27     47GO:0000781; C:chromosome, telomeric region; ISS:UniProtKB.::GO:0016605; C:PML body; ISS:UniProtKB.::GO:0030915; C:Smc5-Smc6 complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0090398; P:cellular senescence; ISS:UniProtKB.::GO:0000724; P:double-strand break repair via homologous recombination; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0034184; P:positive regulation of maintenance of mitotic sister chromatid cohesion; ISS:UniProtKB.::GO:0045842; P:positive regulation of mitotic metaphase/anaphase transition; ISS:UniProtKB.::GO:0000722; P:telomere maintenance via recombination; ISS:UniProtKB.
93P53692    1140   SMC6_SCHPO Structural maintenance of chromoso...830.35     38.9     31     49GO:0005634; C:nucleus; IDA:PomBase.::GO:0030915; C:Smc5-Smc6 complex; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:PomBase.
GO:0000724; P:double-strand break repair via homologous recombination; TAS:PomBase.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0048478; P:replication fork protection; IC:PomBase.
94Q802R8    1090   SMC6_TAKRU Structural maintenance of chromoso...4320.064     41.2     24     39GO:0000781; C:chromosome, telomeric region; ISS:UniProtKB.::GO:0016605; C:PML body; ISS:UniProtKB.::GO:0030915; C:Smc5-Smc6 complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0090398; P:cellular senescence; ISS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0000722; P:telomere maintenance via recombination; ISS:UniProtKB.
95Q58718    1005   RAD50_METJA DNA double-strand break repair Ra...3720.007     44.3     24     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
96Q8CG46    1101   SMC5_MOUSE Structural maintenance of chromoso...830.087     40.8     28     49GO:0000781; C:chromosome, telomeric region; ISS:UniProtKB.::GO:0016605; C:PML body; ISS:UniProtKB.::GO:0030915; C:Smc5-Smc6 complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0090398; P:cellular senescence; ISS:UniProtKB.::GO:0000724; P:double-strand break repair via homologous recombination; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0034184; P:positive regulation of maintenance of mitotic sister chromatid cohesion; ISS:UniProtKB.::GO:0045842; P:positive regulation of mitotic metaphase/anaphase transition; ISS:UniProtKB.::GO:0000722; P:telomere maintenance via recombination; ISS:UniProtKB.
97Q805A1    1065   SMC5_XENLA Structural maintenance of chromoso...3622.2     36.2     20     44GO:0000781; C:chromosome, telomeric region; ISS:UniProtKB.::GO:0009295; C:nucleoid; IEA:InterPro.::GO:0016605; C:PML body; ISS:UniProtKB.::GO:0030915; C:Smc5-Smc6 complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0090398; P:cellular senescence; ISS:UniProtKB.::GO:0030261; P:chromosome condensation; IEA:InterPro.::GO:0007059; P:chromosome segregation; IEA:InterPro.::GO:0000724; P:double-strand break repair via homologous recombination; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0034184; P:positive regulation of maintenance of mitotic sister chromatid cohesion; ISS:UniProtKB.::GO:0045842; P:positive regulation of mitotic metaphase/anaphase transition; ISS:UniProtKB.::GO:0000722; P:telomere maintenance via recombination; ISS:UniProtKB.
98Q08204    1093   SMC5_YEAST Structural maintenance of chromoso...3250.24     39.3     25     43GO:0005634; C:nucleus; IDA:SGD.::GO:0030915; C:Smc5-Smc6 complex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IDA:SGD.::GO:0003684; F:damaged DNA binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003697; F:single-stranded DNA binding; IDA:SGD.
GO:0034500; P:rDNA separation; IMP:SGD.::GO:0000725; P:recombinational repair; IPI:SGD.::GO:0071139; P:resolution of recombination intermediates; IMP:SGD.
99Q5L3Y9    372   RECF_GEOKA DNA replication and repair protein...630.036     41.6     44     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
100Q5JHN1    883   RAD50_PYRKO DNA double-strand break repair Ra...1060.036     42     29     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
101Q9YFZ1    919   RAD50_AERPE DNA double-strand break repair Ra...630.13     40.4     38     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
102Q196W6    829   VF050_IIV3 Uncharacterized protein 094L OS=In...500.051     41.6     40     52
103Q14789    3259   GOGB1_HUMAN Golgin subfamily B member 1 OS=Ho...1450.059     41.6     30     50GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IDA:UniProtKB.::GO:0000139; C:Golgi membrane; TAS:ProtInc.::GO:0005795; C:Golgi stack; TAS:ProtInc.::GO:0016021; C:integral to membrane; TAS:ProtInc.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007030; P:Golgi organization; TAS:ProtInc.
104O58687    879   RAD50_PYRHO DNA double-strand break repair Ra...1165.3     35     23     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
105C5BUP6    397   RECF_BEUC1 DNA replication and repair protein...500.08     40.4     42     68GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
106Q03I57    374   RECF_PEDPA DNA replication and repair protein...600.11     40     40     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
107Q9WXF2    564   RECN_DEIRA DNA repair protein recN OS=LMG 405...580.11     40.4     34     57
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
108Q74M31    374   RECF_LACJO DNA replication and repair protein...660.17     39.3     36     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
109O13710    1076   SMC5_SCHPO Structural maintenance of chromoso...464.9     35     28     61GO:0000935; C:barrier septum; IEA:UniProtKB-SubCell.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0030915; C:Smc5-Smc6 complex; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:PomBase.
GO:0000724; P:double-strand break repair via homologous recombination; TAS:PomBase.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0048478; P:replication fork protection; IC:PomBase.
110B0BRG1    360   RECF_ACTPJ DNA replication and repair protein...1900.21     39.3     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
111P24718    360   RECF_ACTPL DNA replication and repair protein...1900.21     39.3     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
112B3GZJ3    360   RECF_ACTP7 DNA replication and repair protein...1900.22     38.9     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
113Q047F1    374   RECF_LACGA DNA replication and repair protein...660.23     38.9     36     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
114C5D330    374   RECF_GEOSW DNA replication and repair protein...630.3     38.5     41     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
115O33600    886   RAD50_SULAC DNA double-strand break repair Ra...500.4     38.5     44     60
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
116Q96YR5    879   RAD50_SULTO DNA double-strand break repair Ra...1990.41     38.5     26     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
117A4IFI1    688   CC157_BOVIN Coiled-coil domain-containing pro...1740.45     38.5     26     51
118Q8TRL1    1074   RAD50_METAC DNA double-strand break repair Ra...710.47     38.5     35     58
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
119Q4QLR9    359   RECF_HAEI8 DNA replication and repair protein...2460.5     37.7     24     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
120A3MY75    360   RECF_ACTP2 DNA replication and repair protein...1900.59     37.7     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
121Q60902    907   EP15R_MOUSE Epidermal growth factor receptor ...1870.62     38.1     25     48GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
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