Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFL005W
Length:
215
Number of sequences:
5887
Description:
YFL005W SEC4 SGDID:S000001889, Chr VI from 130334-130981, Genome Release 64-1-1, Verified ORF, "Rab family GTPase essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
961Q8IXI2    618   MIRO1_HUMAN Mitochondrial Rho GTPase 1 OS=Hom...1690.00000005     55.8     27     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0031307; C:integral to mitochondrial outer membrane; IDA:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006915; P:apoptotic process; IMP:UniProtKB.::GO:0019725; P:cellular homeostasis; IMP:UniProtKB.::GO:0047497; P:mitochondrion transport along microtubule; IMP:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
962O23778    181   ARF1_CATRO ADP-ribosylation factor 1 OS=Catha...1260.00000005     53.9     27     48GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
963Q8BG51    631   MIRO1_MOUSE Mitochondrial Rho GTPase 1 OS=Mus...1690.00000006     55.8     27     49GO:0031307; C:integral to mitochondrial outer membrane; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0019725; P:cellular homeostasis; ISS:UniProtKB.::GO:0047497; P:mitochondrion transport along microtubule; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
964Q5E9M9    618   MIRO2_BOVIN Mitochondrial Rho GTPase 2 OS=Bos...1690.00000006     55.8     28     47GO:0031307; C:integral to mitochondrial outer membrane; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0019725; P:cellular homeostasis; ISS:UniProtKB.::GO:0047497; P:mitochondrion transport along microtubule; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
965Q7TSA0    622   MIRO2_RAT Mitochondrial Rho GTPase 2 OS=Rattu...1710.00000006     55.8     29     49GO:0031307; C:integral to mitochondrial outer membrane; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0019725; P:cellular homeostasis; ISS:UniProtKB.::GO:0047497; P:mitochondrion transport along microtubule; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
966Q2HJF8    631   MIRO1_BOVIN Mitochondrial Rho GTPase 1 OS=Bos...1690.00000006     55.8     27     49GO:0031307; C:integral to mitochondrial outer membrane; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0019725; P:cellular homeostasis; ISS:UniProtKB.::GO:0047497; P:mitochondrion transport along microtubule; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
967O95661    229   DIRA3_HUMAN GTP-binding protein Di-Ras3 OS=Ho...1500.00000006     54.7     28     45GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.
GO:0000079; P:regulation of cyclin-dependent protein kinase activity; TAS:ProtInc.::GO:0006349; P:regulation of gene expression by genetic imprinting; TAS:ProtInc.::GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc.
968Q8VEL9    341   REM2_MOUSE GTP-binding protein REM 2 OS=Mus m...1640.00000007     55.1     27     49GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
969Q9WTY2    341   REM2_RAT GTP-binding protein REM 2 OS=Rattus ...1590.00000007     55.1     27     51GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005525; F:GTP binding; IDA:RGD.::GO:0003924; F:GTPase activity; IDA:RGD.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
970Q94263    625   MIRO_CAEEL Mitochondrial Rho GTPase OS=Caenor...1730.0000001     55.1     28     47GO:0031307; C:integral to mitochondrial outer membrane; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0019725; P:cellular homeostasis; ISS:UniProtKB.::GO:0047497; P:mitochondrion transport along microtubule; ISS:UniProtKB.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
971P25160    180   ARL1_DROME ADP-ribosylation factor-like prote...1340.0000001     53.1     30     46GO:0005794; C:Golgi apparatus; IDA:FlyBase.
GO:0005525; F:GTP binding; IDA:FlyBase.
GO:0033227; P:dsRNA transport; IMP:FlyBase.::GO:0090158; P:endoplasmic reticulum membrane organization; IMP:FlyBase.::GO:0016197; P:endosome transport; TAS:FlyBase.::GO:0007030; P:Golgi organization; IMP:FlyBase.::GO:0007269; P:neurotransmitter secretion; TAS:FlyBase.::GO:0030334; P:regulation of cell migration; IMP:FlyBase.::GO:0060628; P:regulation of ER to Golgi vesicle-mediated transport; IMP:FlyBase.::GO:0070861; P:regulation of protein exit from endoplasmic reticulum; IMP:FlyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0048488; P:synaptic vesicle endocytosis; TAS:FlyBase.
972P40945    180   ARF2_DROME ADP-ribosylation factor 2 OS=Droso...1310.0000001     53.1     27     47GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003956; F:NAD(P)+-protein-arginine ADP-ribosyltransferase activity; IDA:FlyBase.
GO:0016197; P:endosome transport; TAS:FlyBase.::GO:0007269; P:neurotransmitter secretion; TAS:FlyBase.::GO:0006471; P:protein ADP-ribosylation; IDA:FlyBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0048488; P:synaptic vesicle endocytosis; TAS:FlyBase.
973P61751    180   ARF4_RAT ADP-ribosylation factor 4 OS=Rattus ...1310.0000001     53.1     28     47GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007420; P:brain development; IEP:RGD.::GO:0007173; P:epidermal growth factor receptor signaling pathway; IDA:RGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0048678; P:response to axon injury; IEP:RGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
974P61750    180   ARF4_MOUSE ADP-ribosylation factor 4 OS=Mus m...1310.0000001     53.1     28     47GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0005525; F:GTP binding; TAS:MGI.
GO:0015031; P:protein transport; TAS:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
975P40617    200   ARL4A_HUMAN ADP-ribosylation factor-like prot...1540.0000001     53.1     29     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
976Q54I24    216   ARFD_DICDI ADP-ribosylation factor D OS=Dicty...1370.0000002     53.5     29     50GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
977P51824    197   ARF1_SOLTU ADP-ribosylation factor 1 OS=Solan...1260.0000002     52.8     27     48GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
978Q553R6    444   RABX_DICDI Ras-related protein RabX OS=Dictyo...750.0000002     53.9     31     59GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
979Q20758    180   ARL1_CAEEL ADP-ribosylation factor-like prote...1690.0000002     52.4     30     47GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
980Q06849    184   ARL2_DROME ADP-ribosylation factor-like prote...1360.0000002     52.4     31     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0016197; P:endosome transport; TAS:FlyBase.::GO:0007269; P:neurotransmitter secretion; TAS:FlyBase.::GO:0006471; P:protein ADP-ribosylation; ISS:FlyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0048488; P:synaptic vesicle endocytosis; TAS:FlyBase.
981P84082    181   ARF2_RAT ADP-ribosylation factor 2 OS=Rattus ...1260.0000003     52     28     48GO:0005794; C:Golgi apparatus; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
982Q8BSL7    181   ARF2_MOUSE ADP-ribosylation factor 2 OS=Mus m...1260.0000003     52     28     48GO:0005794; C:Golgi apparatus; IDA:MGI.
GO:0005525; F:GTP binding; TAS:MGI.
GO:0015031; P:protein transport; TAS:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
983P84081    181   ARF2_BOVIN ADP-ribosylation factor 2 OS=Bos t...1260.0000003     52     28     48GO:0005794; C:Golgi apparatus; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
984Q9Y272    281   RASD1_HUMAN Dexamethasone-induced Ras-related...1760.0000003     53.1     25     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.
GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
985Q5RCF1    180   ARF4_PONAB ADP-ribosylation factor 4 OS=Pongo...1330.0000004     51.6     28     46GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
986P18085    180   ARF4_HUMAN ADP-ribosylation factor 4 OS=Homo ...1330.0000004     51.6     28     46GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
987P61214    200   ARL4A_RAT ADP-ribosylation factor-like protei...1340.0000004     52     30     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; ISS:UniProtKB.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
988P61213    200   ARL4A_MOUSE ADP-ribosylation factor-like prot...1340.0000004     52     30     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; TAS:MGI.
GO:0050873; P:brown fat cell differentiation; IDA:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
989Q3T0M9    200   ARL4A_BOVIN ADP-ribosylation factor-like prot...1340.0000004     52     30     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; ISS:UniProtKB.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
990Q86JP5    307   RABR_DICDI Ras-related protein RabR OS=Dictyo...2290.0000004     53.1     25     37GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0006972; P:hyperosmotic response; IEP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
991Q9JKF8    280   RASD1_RAT Dexamethasone-induced Ras-related p...1760.0000005     52.8     25     47GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0007263; P:nitric oxide mediated signal transduction; IDA:RGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
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