Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFL005W
Length:
215
Number of sequences:
5887
Description:
YFL005W SEC4 SGDID:S000001889, Chr VI from 130334-130981, Genome Release 64-1-1, Verified ORF, "Rab family GTPase essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q6PHN9    201   RAB35_MOUSE Ras-related protein Rab-35 OS=Mus...1682e-58     189     53     75GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:MGI.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
92Q15286    201   RAB35_HUMAN Ras-related protein Rab-35 OS=Hom...1682e-58     189     53     75GO:0031253; C:cell projection membrane; IDA:UniProtKB.::GO:0045334; C:clathrin-coated endocytic vesicle; IDA:UniProtKB.::GO:0005905; C:coated pit; IDA:UniProtKB.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0045171; C:intercellular bridge; IDA:UniProtKB.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:UniProtKB.
GO:0000910; P:cytokinesis; IMP:UniProtKB.::GO:0016197; P:endosome transport; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
93P59190    212   RAB15_HUMAN Ras-related protein Rab-15 OS=Hom...1682e-58     189     51     75GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
94Q94986    219   RAB3_CAEEL Ras-related protein Rab-3 OS=Caeno...1854e-58     189     48     74GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
95Q9CZT8    219   RAB3B_MOUSE Ras-related protein Rab-3B OS=Mus...1744e-58     189     50     74GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0008021; C:synaptic vesicle; IDA:MGI.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.
GO:0018125; P:peptidyl-cysteine methylation; IDA:MGI.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0017157; P:regulation of exocytosis; IDA:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
96Q5KTJ7    219   RAB3B_MESAU Ras-related protein Rab-3B OS=Mes...1744e-58     189     50     74GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
97P10948    219   RAB3B_BOVIN Ras-related protein Rab-3B OS=Bos...1745e-58     189     50     74GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
98Q63941    219   RAB3B_RAT Ras-related protein Rab-3B OS=Rattu...1747e-58     188     49     74GO:0005829; C:cytosol; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; NAS:RGD.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0017157; P:regulation of exocytosis; TAS:RGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
99P10949    227   RAB3C_BOVIN Ras-related protein Rab-3C OS=Bos...1717e-58     188     50     75GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
100Q96E17    227   RAB3C_HUMAN Ras-related protein Rab-3C OS=Hom...1717e-58     188     50     75GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
101Q29RR0    256   RAB26_BOVIN Ras-related protein Rab-26 OS=Bos...1781e-57     189     50     72GO:0031226; C:intrinsic to plasma membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; ISS:UniProtKB.
GO:0035272; P:exocrine system development; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0017157; P:regulation of exocytosis; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
102P51156    257   RAB26_RAT Ras-related protein Rab-26 OS=Rattu...1742e-57     188     51     74GO:0031226; C:intrinsic to plasma membrane; IDA:UniProtKB.
GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; TAS:RGD.
GO:0035272; P:exocrine system development; IDA:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0017157; P:regulation of exocytosis; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; TAS:RGD.
103P62824    227   RAB3C_RAT Ras-related protein Rab-3C OS=Rattu...1712e-57     187     50     75GO:0005829; C:cytosol; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0017156; P:calcium ion-dependent exocytosis; TAS:RGD.::GO:0007269; P:neurotransmitter secretion; TAS:RGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
104P62823    227   RAB3C_MOUSE Ras-related protein Rab-3C OS=Mus...1712e-57     187     50     75GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0008021; C:synaptic vesicle; IDA:MGI.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0017157; P:regulation of exocytosis; IDA:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
105Q9ULW5    256   RAB26_HUMAN Ras-related protein Rab-26 OS=Hom...1693e-57     187     51     74GO:0031226; C:intrinsic to plasma membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; ISS:UniProtKB.
GO:0035272; P:exocrine system development; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0017157; P:regulation of exocytosis; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
106O76173    201   RAB1C_DICDI Ras-related protein Rab-1C OS=Dic...1736e-57     185     50     73
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
107Q4UB16    220   RAB1_THEAN Ras-related protein Rab-1 OS=Theil...1721e-56     185     51     76GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
108Q8WUD1    216   RAB2B_HUMAN Ras-related protein Rab-2B OS=Hom...2151e-56     185     43     63GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0045921; P:positive regulation of exocytosis; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
109Q504M8    260   RAB26_MOUSE Ras-related protein Rab-26 OS=Mus...1724e-56     185     50     73GO:0031226; C:intrinsic to plasma membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:MGI.
GO:0035272; P:exocrine system development; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0017157; P:regulation of exocytosis; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
110P53994    212   RAB2A_MOUSE Ras-related protein Rab-2A OS=Mus...1701e-55     182     49     71GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0033116; C:endoplasmic reticulum-Golgi intermediate compartment membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0006886; P:intracellular protein transport; TAS:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
111Q38922    211   RAB1B_ARATH Ras-related protein RABB1b OS=Ara...2172e-55     182     41     60GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IDA:TAIR.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
112Q5R6B6    212   RAB2A_PONAB Ras-related protein Rab-2A OS=Pon...1702e-55     181     49     71GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0033116; C:endoplasmic reticulum-Golgi intermediate compartment membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
113Q4R4X6    212   RAB2A_MACFA Ras-related protein Rab-2A OS=Mac...1702e-55     181     49     71GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0033116; C:endoplasmic reticulum-Golgi intermediate compartment membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
114P61019    212   RAB2A_HUMAN Ras-related protein Rab-2A OS=Hom...1702e-55     181     49     71GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0033116; C:endoplasmic reticulum-Golgi intermediate compartment membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; IDA:UniProtKB.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:UniProtKB.
GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:ProtInc.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
115P61105    212   RAB2A_CANFA Ras-related protein Rab-2A OS=Can...1702e-55     181     49     71GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0033116; C:endoplasmic reticulum-Golgi intermediate compartment membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
116Q01971    212   RAB2A_RABIT Ras-related protein Rab-2A OS=Ory...1702e-55     181     49     71GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0033116; C:endoplasmic reticulum-Golgi intermediate compartment membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
117Q90965    212   RAB2A_CHICK Ras-related protein Rab-2A OS=Gal...1702e-55     181     49     71GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0033116; C:endoplasmic reticulum-Golgi intermediate compartment membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
118P05712    212   RAB2A_RAT Ras-related protein Rab-2A OS=Rattu...1704e-55     181     48     71GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0033116; C:endoplasmic reticulum-Golgi intermediate compartment membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:HGNC.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032482; P:Rab protein signal transduction; IC:RGD.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
119P51152    208   RAB12_CANFA Ras-related protein Rab-12 OS=Can...1726e-55     180     51     75GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
120Q05975    212   RAB2_LYMST Ras-related protein Rab-2 OS=Lymna...1706e-55     180     49     70GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0033116; C:endoplasmic reticulum-Golgi intermediate compartment membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
121Q96AX2    223   RAB37_HUMAN Ras-related protein Rab-37 OS=Hom...1769e-55     180     46     72GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IDA:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
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