Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFL005W
Length:
215
Number of sequences:
5887
Description:
YFL005W SEC4 SGDID:S000001889, Chr VI from 130334-130981, Genome Release 64-1-1, Verified ORF, "Rab family GTPase essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
871Q5R541    296   GEM_PONAB GTP-binding protein GEM OS=Pongo ab...1890.0000000003     62     27     49GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
872P51645    175   ARF6_XENLA ADP-ribosylation factor 6 OS=Xenop...1190.0000000003     60.1     30     48GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0031527; C:filopodium membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
873P55043    306   RAD_RAT GTP-binding protein RAD OS=Rattus nor...1790.0000000005     61.2     29     49GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0030308; P:negative regulation of cell growth; IMP:RGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
874O35929    297   REM1_MOUSE GTP-binding protein REM 1 OS=Mus m...1600.0000000005     61.2     26     49GO:0016020; C:membrane; IEA:InterPro.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
875P61208    192   ARL4C_MOUSE ADP-ribosylation factor-like prot...1510.0000000006     59.7     30     45GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0043014; F:alpha-tubulin binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0032456; P:endocytic recycling; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
876P56559    192   ARL4C_HUMAN ADP-ribosylation factor-like prot...1510.0000000006     59.7     30     45GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:ProtInc.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0043014; F:alpha-tubulin binding; IDA:UniProtKB.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.
GO:0032456; P:endocytic recycling; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
877Q6DIS1    616   MIRO2_XENTR Mitochondrial Rho GTPase 2 OS=Xen...1311.8     33.1     24     40GO:0031307; C:integral to mitochondrial outer membrane; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0019725; P:cellular homeostasis; ISS:UniProtKB.::GO:0047497; P:mitochondrion transport along microtubule; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
878Q54JJ3    189   ARFH_DICDI ADP-ribosylation factor H OS=Dicty...1300.0000000006     59.3     31     48GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
879Q8N4Z0    105   RAB42_HUMAN Putative Ras-related protein Rab-...850.0000000007     57.8     40     60GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
880Q8IYK8    340   REM2_HUMAN GTP-binding protein REM 2 OS=Homo ...1700.0000000008     60.8     29     48GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
881Q6P068    179   ARL5C_MOUSE ADP-ribosylation factor-like prot...1300.0000000009     58.9     29     52GO:0005622; C:intracellular; IEA:InterPro.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
882Q8N4G2    192   ARL14_HUMAN ADP-ribosylation factor-like prot...1260.000000001     58.9     29     50GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
883P49702    180   ARF5_CHICK ADP-ribosylation factor 5 OS=Gallu...1420.000000001     58.5     29     49GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:AgBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
884Q7RVM2    185   ARF_NEUCR ADP-ribosylation factor OS=1257 / F...1380.000000001     58.5     28     49GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
885O88667    308   RAD_MOUSE GTP-binding protein RAD OS=Mus musc...1780.000000002     59.7     29     51GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
886Q32LU1    617   MIRO2_DANRE Mitochondrial Rho GTPase 2 OS=Dan...1690.000000002     60.5     30     49GO:0031307; C:integral to mitochondrial outer membrane; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0019725; P:cellular homeostasis; ISS:UniProtKB.::GO:0047497; P:mitochondrion transport along microtubule; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
887P34727    183   ARF_AJECA ADP-ribosylation factor OS=capsulat...1440.000000002     58.2     27     49GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
888Q3SXC5    192   ARL14_MOUSE ADP-ribosylation factor-like prot...1180.000000002     58.2     31     53GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
889Q7Z444    233   RASE_HUMAN GTPase ERas OS=Homo sapiens (Human...1610.000000003     58.5     31     45GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
890P51821    181   ARF1_CHLRE ADP-ribosylation factor 1 OS=Chlam...1260.000000003     57.4     29     48GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
891O00909    182   ARF1_DICDI ADP-ribosylation factor 1 OS=Dicty...1310.000000003     57.4     29     48GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0005525; F:GTP binding; IDA:dictyBase.::GO:0005515; F:protein binding; IPI:dictyBase.
GO:0015031; P:protein transport; ISS:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; ISS:dictyBase.
892P91924    183   ARF_DUGJA ADP-ribosylation factor OS=Dugesia ...1260.000000003     57.4     29     49GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
893P22274    179   ARF_CANAL ADP-ribosylation factor OS=Candida ...1310.000000003     57.4     27     49GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
894P51823    181   ARF2_ORYSJ ADP-ribosylation factor 2 OS=Oryza...1260.000000003     57.4     29     48GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0006886; P:intracellular protein transport; IEP:Gramene.::GO:0006471; P:protein ADP-ribosylation; IEP:Gramene.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEP:Gramene.
895Q06396    181   ARF1_ORYSJ ADP-ribosylation factor 1 OS=Oryza...1260.000000003     57.4     29     48GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
896Q5ZM83    618   MIRO2_CHICK Mitochondrial Rho GTPase 2 OS=Gal...1690.000000004     59.3     30     49GO:0031307; C:integral to mitochondrial outer membrane; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0019725; P:cellular homeostasis; ISS:UniProtKB.::GO:0047497; P:mitochondrion transport along microtubule; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
897P0CM16    182   ARF_CRYNJ ADP-ribosylation factor OS=ATCC MYA...1260.000000004     57     28     48GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
898P0CM17    182   ARF_CRYNB ADP-ribosylation factor OS=(Filobas...1260.000000004     57     28     48GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
899Q7TN89    227   RASE_MOUSE GTPase ERas OS=Mus musculus (Mouse...1610.000000004     57.8     30     46GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
900Q627K4    184   ARL2_CAEBR ADP-ribosylation factor-like prote...1180.000000004     57     31     51GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0030540; P:female genitalia development; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
901P40616    181   ARL1_HUMAN ADP-ribosylation factor-like prote...1410.000000005     56.6     30     50GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005802; C:trans-Golgi network; ISS:UniProtKB.
GO:0008047; F:enzyme activator activity; IDA:UniProtKB.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
GO:0031584; P:activation of phospholipase D activity; IDA:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0034067; P:protein localization in Golgi apparatus; IMP:UniProtKB.::GO:0042147; P:retrograde transport, endosome to Golgi; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0009404; P:toxin metabolic process; IDA:UniProtKB.
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