Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFL005W
Length:
215
Number of sequences:
5887
Description:
YFL005W SEC4 SGDID:S000001889, Chr VI from 130334-130981, Genome Release 64-1-1, Verified ORF, "Rab family GTPase essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
841Q54V41    188   ARFK_DICDI ADP-ribosylation factor K OS=Dicty...1270.00000000004     62.8     34     49GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
842Q9GPR2    205   RACI_DICDI Rho-related protein racI OS=Dictyo...1720.00000000004     62.8     23     47GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
843Q08E00    266   RASLC_BOVIN Ras-like protein family member 12...1880.00000000005     63.9     29     48GO:0016020; C:membrane; IEA:InterPro.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
844P34150    254   RACD_DICDI Rho-related protein racD OS=Dictyo...1530.00000000005     63.5     30     48GO:0005622; C:intracellular; IEA:InterPro.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
845Q9Y7Z2    184   ARF6_SCHPO ADP-ribosylation factor 6 OS=Schiz...1310.00000000005     62.4     27     50GO:0030428; C:cell septum; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0000139; C:Golgi membrane; ISS:PomBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; ISS:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0006888; P:ER to Golgi vesicle-mediated transport; ISS:PomBase.::GO:0006886; P:intracellular protein transport; IC:PomBase.::GO:0007264; P:small GTPase mediated signal transduction; NAS:PomBase.
846Q54V47    188   ARFJ_DICDI ADP-ribosylation factor J OS=Dicty...1270.00000000006     62.4     32     49GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
847Q7SZ59    255   RASLC_DANRE Ras-like protein family member 12...1690.00000000006     63.2     30     52GO:0016020; C:membrane; IEA:InterPro.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
848P55040    296   GEM_HUMAN GTP-binding protein GEM OS=Homo sap...1890.00000000006     63.9     28     50GO:0009898; C:internal side of plasma membrane; IDA:BHF-UCL.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0019003; F:GDP binding; IDA:BHF-UCL.::GO:0005525; F:GTP binding; IDA:BHF-UCL.::GO:0003924; F:GTPase activity; IDA:BHF-UCL.::GO:0000287; F:magnesium ion binding; IDA:BHF-UCL.
GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.::GO:0006955; P:immune response; TAS:ProtInc.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
849P55041    295   GEM_MOUSE GTP-binding protein GEM OS=Mus musc...1890.00000000006     63.9     28     50GO:0005634; C:nucleus; IDA:MGI.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
850Q54R04    185   ARL8_DICDI ADP-ribosylation factor-like prote...1190.00000000007     62     33     49GO:0005622; C:intracellular; IEA:InterPro.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
851O94103    190   CDC42_COLGL Cell division control protein 42 ...1700.00000000007     62     25     47GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
852P62332    175   ARF6_RAT ADP-ribosylation factor 6 OS=Rattus ...1190.00000000007     61.6     30     49GO:0005769; C:early endosome; IDA:RGD.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0031527; C:filopodium membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IDA:RGD.::GO:0001726; C:ruffle; IDA:RGD.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0016358; P:dendrite development; TAS:RGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0060998; P:regulation of dendritic spine development; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
853Q007T5    175   ARF6_PIG ADP-ribosylation factor 6 OS=Sus scr...1190.00000000007     61.6     30     49GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0031527; C:filopodium membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0060998; P:regulation of dendritic spine development; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
854P62331    175   ARF6_MOUSE ADP-ribosylation factor 6 OS=Mus m...1190.00000000007     61.6     30     49GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0031527; C:filopodium membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; TAS:BHF-UCL.::GO:0003924; F:GTPase activity; TAS:BHF-UCL.
GO:0006915; P:apoptotic process; IMP:MGI.::GO:0090162; P:establishment of epithelial cell polarity; IMP:MGI.::GO:0001889; P:liver development; IMP:MGI.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IDA:BHF-UCL.::GO:0034394; P:protein localization at cell surface; IDA:BHF-UCL.::GO:0015031; P:protein transport; TAS:MGI.::GO:0060998; P:regulation of dendritic spine development; IMP:UniProtKB.::GO:0034143; P:regulation of toll-like receptor 4 signaling pathway; NAS:BHF-UCL.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
855P62330    175   ARF6_HUMAN ADP-ribosylation factor 6 OS=Homo ...1190.00000000007     61.6     30     49GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0031527; C:filopodium membrane; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0001726; C:ruffle; IDA:UniProtKB.
GO:0005525; F:GTP binding; TAS:UniProtKB.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0031996; F:thioesterase binding; IPI:UniProtKB.
GO:0007155; P:cell adhesion; TAS:UniProtKB.::GO:0006928; P:cellular component movement; TAS:UniProtKB.::GO:0030866; P:cortical actin cytoskeleton organization; IMP:UniProtKB.::GO:0048261; P:negative regulation of receptor-mediated endocytosis; TAS:UniProtKB.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:UniProtKB.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; ISS:BHF-UCL.::GO:0034394; P:protein localization at cell surface; ISS:BHF-UCL.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0060998; P:regulation of dendritic spine development; ISS:UniProtKB.::GO:0051489; P:regulation of filopodium assembly; IDA:UniProtKB.::GO:0035020; P:regulation of Rac protein signal transduction; IDA:UniProtKB.::GO:0031529; P:ruffle organization; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; TAS:UniProtKB.
856O75628    298   REM1_HUMAN GTP-binding protein REM 1 OS=Homo ...1590.00000000008     63.5     28     49GO:0016020; C:membrane; IEA:InterPro.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
857P11076    181   ARF1_YEAST ADP-ribosylation factor 1 OS=Sacch...1310.00000000009     61.6     30     47GO:0005829; C:cytosol; TAS:SGD.::GO:0005798; C:Golgi-associated vesicle; TAS:SGD.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006888; P:ER to Golgi vesicle-mediated transport; IDA:SGD.::GO:0006893; P:Golgi to plasma membrane transport; IGI:SGD.::GO:0006891; P:intra-Golgi vesicle-mediated transport; TAS:SGD.::GO:0016236; P:macroautophagy; IMP:SGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
858P26990    175   ARF6_CHICK ADP-ribosylation factor 6 OS=Gallu...1190.00000000009     61.6     30     49GO:0005938; C:cell cortex; ISS:AgBase.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0031527; C:filopodium membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; ISS:AgBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030866; P:cortical actin cytoskeleton organization; ISS:AgBase.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0030838; P:positive regulation of actin filament polymerization; ISS:AgBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0035020; P:regulation of Rac protein signal transduction; ISS:AgBase.::GO:0031529; P:ruffle organization; ISS:AgBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
859A6ZSH6    417   YPT11_YEAS7 GTP-binding protein YPT11 OS=Sacc...1130.00000000009     63.9     34     58GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0005934; C:cellular bud tip; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
860B3LPD8    417   YPT11_YEAS1 GTP-binding protein YPT11 OS=Sacc...1130.00000000009     63.9     34     58GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0005934; C:cellular bud tip; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
861P48559    417   YPT11_YEAST GTP-binding protein YPT11 OS=Sacc...1130.00000000009     63.9     34     58GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000131; C:incipient cellular bud site; IDA:SGD.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IPI:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0048309; P:endoplasmic reticulum inheritance; IMP:SGD.::GO:0048313; P:Golgi inheritance; IGI:SGD.::GO:0051645; P:Golgi localization; IMP:SGD.::GO:0000001; P:mitochondrion inheritance; IMP:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
862B5VQB6    417   YPT11_YEAS6 GTP-binding protein YPT11 OS=Sacc...1130.00000000009     63.9     34     58GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0005934; C:cellular bud tip; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
863P19146    181   ARF2_YEAST ADP-ribosylation factor 2 OS=Sacch...1310.0000000001     61.2     30     47GO:0005829; C:cytosol; TAS:SGD.::GO:0005798; C:Golgi-associated vesicle; TAS:SGD.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:SGD.::GO:0006891; P:intra-Golgi vesicle-mediated transport; TAS:SGD.::GO:0016236; P:macroautophagy; IMP:SGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
864Q75A26    181   ARF_ASHGO ADP-ribosylation factor OS=Y-1056) ...1310.0000000001     60.8     30     47GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
865Q5FVY2    247   RSLBB_XENTR Ras-like protein family member 11...1730.0000000002     62     28     52GO:0016020; C:membrane; IEA:InterPro.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
866Q54HK2    190   ARFF_DICDI ADP-ribosylation factor F OS=Dicty...1330.0000000002     60.8     32     47GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
867Q54FK2    184   RABN2_DICDI Ras-related protein RabN2 OS=Dict...1730.0000000002     60.8     27     48
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
868P40946    175   ARF3_DROME ADP-ribosylation factor 3 OS=Droso...1190.0000000002     60.5     29     49GO:0005829; C:cytosol; IDA:FlyBase.::GO:0005769; C:early endosome; IDA:FlyBase.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:FlyBase.::GO:0055037; C:recycling endosome; IDA:FlyBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003956; F:NAD(P)+-protein-arginine ADP-ribosyltransferase activity; IDA:FlyBase.
GO:0030036; P:actin cytoskeleton organization; IMP:FlyBase.::GO:0016197; P:endosome transport; TAS:FlyBase.::GO:0007112; P:male meiosis cytokinesis; IMP:FlyBase.::GO:0007520; P:myoblast fusion; IMP:FlyBase.::GO:0007269; P:neurotransmitter secretion; NAS:FlyBase.::GO:0006471; P:protein ADP-ribosylation; IDA:FlyBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0007283; P:spermatogenesis; IMP:FlyBase.::GO:0048488; P:synaptic vesicle endocytosis; TAS:FlyBase.
869Q5R579    201   ARFRP_PONAB ADP-ribosylation factor-related p...1320.0000000003     60.5     33     50GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
870Q13795    201   ARFRP_HUMAN ADP-ribosylation factor-related p...1320.0000000003     60.5     33     50GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0005802; C:trans-Golgi network; IDA:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.
GO:0043001; P:Golgi to plasma membrane protein transport; IMP:UniProtKB.::GO:0034067; P:protein localization in Golgi apparatus; IMP:UniProtKB.::GO:0042147; P:retrograde transport, endosome to Golgi; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
871Q5R541    296   GEM_PONAB GTP-binding protein GEM OS=Pongo ab...1890.0000000003     62     27     49GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
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