Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFL005W
Length:
215
Number of sequences:
5887
Description:
YFL005W SEC4 SGDID:S000001889, Chr VI from 130334-130981, Genome Release 64-1-1, Verified ORF, "Rab family GTPase essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
781Q9EQT3    261   RHOU_MOUSE Rho-related GTP-binding protein Rh...1683e-16     78.2     29     50GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0002102; C:podosome; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IMP:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0030036; P:actin cytoskeleton organization; IDA:MGI.::GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:MGI.::GO:0016601; P:Rac protein signal transduction; IDA:MGI.::GO:0008360; P:regulation of cell shape; IDA:MGI.
782P34144    194   RAC1A_DICDI Rho-related protein rac1A OS=Dict...1684e-16     77.4     29     50GO:0045335; C:phagocytic vesicle; IDA:dictyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:dictyBase.
GO:0030838; P:positive regulation of actin filament polymerization; IDA:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
783A5D7J5    255   RHOU_BOVIN Rho-related GTP-binding protein Rh...1684e-16     78.2     30     49GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0002102; C:podosome; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0008360; P:regulation of cell shape; ISS:UniProtKB.
784Q05058    215   RASL_COPCI 24 kDa Ras-like protein OS=Coprino...1515e-16     77.4     32     52GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
785A8NU18    215   RASL_COPC7 24 kDa Ras-like protein OS=9003) (...1515e-16     77.4     32     52GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
786Q6IMA3    242   RSLBA_RAT Ras-like protein family member 11A ...1686e-16     77.4     30     57GO:0016020; C:membrane; IEA:InterPro.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0045943; P:positive regulation of transcription from RNA polymerase I promoter; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
787Q6IMB1    242   RSLBA_MOUSE Ras-like protein family member 11...1817e-16     77     30     54GO:0016020; C:membrane; IEA:InterPro.::GO:0005730; C:nucleolus; IDA:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0045943; P:positive regulation of transcription from RNA polymerase I promoter; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
788Q9HBH0    211   RHOF_HUMAN Rho-related GTP-binding protein Rh...1878e-16     76.6     27     51GO:0005856; C:cytoskeleton; NAS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; NAS:UniProtKB.
GO:0007015; P:actin filament organization; IDA:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
789Q94124    195   RAC2_CAEEL Ras-related protein rac-2 OS=Caeno...1688e-16     76.6     27     52GO:0030424; C:axon; IDA:WormBase.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IDA:WormBase.
GO:0005525; F:GTP binding; IDA:WormBase.::GO:0003924; F:GTPase activity; IDA:WormBase.
GO:0048846; P:axon extension involved in axon guidance; IGI:WormBase.::GO:0007413; P:axonal fasciculation; IMP:WormBase.::GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0033563; P:dorsal/ventral axon guidance; IGI:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0043652; P:engulfment of apoptotic cell; IMP:WormBase.::GO:0040039; P:inductive cell migration; IMP:WormBase.::GO:0008045; P:motor axon guidance; IGI:WormBase.::GO:0001764; P:neuron migration; IGI:WormBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
790D3Z8L7    218   RRAS_RAT Ras-related protein R-Ras OS=Rattus ...1539e-16     76.6     32     54GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
791P34145    194   RAC1B_DICDI Rho-related protein rac1B OS=Dict...1680.000000000000001     75.9     29     49GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:dictyBase.
GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0043326; P:chemotaxis to folate; TAS:dictyBase.::GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0006897; P:endocytosis; IMP:dictyBase.::GO:0030838; P:positive regulation of actin filament polymerization; IDA:dictyBase.::GO:0008360; P:regulation of cell shape; IMP:dictyBase.::GO:0019953; P:sexual reproduction; IEP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
792O88931    192   RAC2_CAVPO Ras-related C3 botulinum toxin sub...1680.000000000000001     75.9     27     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
793O76321    199   RECG_ENTHI Rho-related protein racG OS=Entamo...1680.000000000000002     75.5     27     52GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
794Q7L0Q8    258   RHOU_HUMAN Rho-related GTP-binding protein Rh...1680.000000000000002     75.9     29     49GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0002102; C:podosome; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
795Q3SZA1    215   RHOF_BOVIN Rho-related GTP-binding protein Rh...1740.000000000000003     75.1     26     52GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
796P38987    245   TEM1_YEAST Protein TEM1 OS=Saccharomyces cere...1620.000000000000003     75.5     28     51GO:0005816; C:spindle pole body; IDA:SGD.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007096; P:regulation of exit from mitosis; TAS:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
797Q6T310    242   RSLBA_HUMAN Ras-like protein family member 11...1680.000000000000003     75.1     30     55GO:0016020; C:membrane; IEA:InterPro.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0045943; P:positive regulation of transcription from RNA polymerase I promoter; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
798Q8TFK3    214   GSP1_YARLI GTP-binding nuclear protein GSP1/R...1610.000000000000004     74.7     29     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
799Q9HF51    224   RHO3_ASHGO GTP-binding protein RHO3 OS=Y-1056...1850.000000000000004     74.7     27     48GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
800P10833    218   RRAS_MOUSE Ras-related protein R-Ras OS=Mus m...1530.000000000000004     74.7     31     54GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0030336; P:negative regulation of cell migration; IGI:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
801Q9H4E5    214   RHOJ_HUMAN Rho-related GTP-binding protein Rh...1830.000000000000006     74.3     25     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; NAS:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; IMP:UniProtKB.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
802Q8BYP3    211   RHOF_MOUSE Rho-related GTP-binding protein Rh...1740.000000000000009     73.6     28     51GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
803P34146    193   RAC1C_DICDI Rho-related protein rac1C OS=Dict...1680.00000000000002     72.4     29     49GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:dictyBase.
GO:0019953; P:sexual reproduction; IEP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
804P28775    217   RAS_LENED Ras-like protein OS=Lentinula edode...1510.00000000000002     72.4     31     52GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
805P31021    208   RHO1_ENTHI Ras-like GTP-binding protein RHO1 ...1740.00000000000003     72     29     52GO:0005622; C:intracellular; IEA:InterPro.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
806O13928    205   RHO3_SCHPO GTP-binding protein rho3 OS=Schizo...1690.00000000000004     71.6     28     52GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0030036; P:actin cytoskeleton organization; IMP:PomBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007163; P:establishment or maintenance of cell polarity; IMP:PomBase.::GO:0000226; P:microtubule cytoskeleton organization; IMP:PomBase.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0010590; P:regulation of cytokinetic cell separation; IMP:PomBase.::GO:0017157; P:regulation of exocytosis; TAS:PomBase.::GO:0007264; P:small GTPase mediated signal transduction; IC:PomBase.
807Q922H7    247   RSLBB_MOUSE Ras-like protein family member 11...1840.00000000000004     72     29     49GO:0016020; C:membrane; IEA:InterPro.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
808P0CQ42    216   RAS_CRYNJ Ras-like protein OS=ATCC MYA-565) (...1510.00000000000004     71.6     30     50GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
809P0CQ43    216   RAS_CRYNB Ras-like protein OS=(Filobasidiella...1510.00000000000004     71.6     30     50GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
810P52198    227   RND2_HUMAN Rho-related GTP-binding protein Rh...1540.00000000000005     71.6     27     55GO:0002080; C:acrosomal membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
811Q9QYM5    227   RND2_MOUSE Rho-related GTP-binding protein Rh...1540.00000000000006     71.2     27     55GO:0002080; C:acrosomal membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:MGI.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
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