Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFL005W
Length:
215
Number of sequences:
5887
Description:
YFL005W SEC4 SGDID:S000001889, Chr VI from 130334-130981, Genome Release 64-1-1, Verified ORF, "Rab family GTPase essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
661Q09914    202   RHO1_SCHPO GTP-binding protein rho1 OS=Schizo...1794e-19     86.3     28     54GO:0000935; C:barrier septum; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0031234; C:extrinsic to internal side of plasma membrane; NAS:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0030427; C:site of polarized growth; TAS:PomBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:PomBase.::GO:0060583; P:regulation of actin cortical patch localization; IGI:PomBase.::GO:0032956; P:regulation of actin cytoskeleton organization; IMP:PomBase.::GO:0032949; P:regulation of alpha-glucan biosynthetic process; IMP:PomBase.::GO:0032955; P:regulation of barrier septum assembly; IMP:PomBase.::GO:0090334; P:regulation of cell wall (1->3)-beta-D-glucan biosynthetic process; TAS:PomBase.::GO:0030100; P:regulation of endocytosis; ISS:PomBase.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IMP:PomBase.::GO:0007266; P:Rho protein signal transduction; TAS:PomBase.
662P42558    216   RAN_CHICK GTP-binding nuclear protein Ran OS=...1584e-19     86.3     29     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
663Q6FR65    214   GSP1_CANGA GTP-binding nuclear protein GSP1/R...1584e-19     86.3     30     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
664Q61820    216   RANT_MOUSE GTP-binding nuclear protein Ran, t...1584e-19     86.3     29     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
665Q6EP31    197   RAC5_ORYSJ Rac-like GTP-binding protein 5 OS=...1784e-19     85.9     29     50
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
666P41917    221   RAN2_ARATH GTP-binding nuclear protein Ran-2 ...1585e-19     86.3     30     52GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005635; C:nuclear envelope; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:TAIR.
GO:0006606; P:protein import into nucleus; TAS:TAIR.::GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
667P22981    184   LET60_CAEEL Ras protein let-60 OS=Caenorhabdi...1605e-19     85.5     33     56GO:0005938; C:cell cortex; IDA:WormBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0007517; P:muscle organ development; IMP:WormBase.::GO:0048477; P:oogenesis; IGI:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0042659; P:regulation of cell fate specification; IMP:WormBase.::GO:0031344; P:regulation of cell projection organization; IMP:WormBase.::GO:0032940; P:secretion by cell; IMP:WormBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0040025; P:vulval development; IMP:WormBase.
668Q24814    196   RACA_ENTHI Rho-related protein racA OS=Entamo...1685e-19     85.5     32     51GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
669Q9YGC0    215   RAN_SALSA GTP-binding nuclear protein Ran OS=...1585e-19     85.9     29     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
670Q01112    192   CDC42_SCHPO Cell division control protein 42 ...1686e-19     85.5     30     51GO:0071521; C:Cdc42 GTPase complex; NAS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0009898; C:internal side of plasma membrane; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0032488; P:Cdc42 protein signal transduction; IC:PomBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:PomBase.::GO:0032955; P:regulation of barrier septum assembly; IMP:PomBase.::GO:0032951; P:regulation of beta-glucan biosynthetic process; IGI:PomBase.::GO:0031137; P:regulation of conjugation with cellular fusion; IMP:PomBase.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IMP:PomBase.
671P17081    205   RHOQ_HUMAN Rho-related GTP-binding protein Rh...1696e-19     85.5     28     52GO:0005884; C:actin filament; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:BHF-UCL.
GO:0032427; F:GBD domain binding; IPI:BHF-UCL.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:BHF-UCL.::GO:0005522; F:profilin binding; IPI:BHF-UCL.
GO:0030866; P:cortical actin cytoskeleton organization; IMP:BHF-UCL.::GO:0008286; P:insulin receptor signaling pathway; IMP:BHF-UCL.::GO:0090005; P:negative regulation of establishment of protein localization in plasma membrane; IMP:BHF-UCL.::GO:0051491; P:positive regulation of filopodium assembly; IDA:BHF-UCL.::GO:0046326; P:positive regulation of glucose import; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0032956; P:regulation of actin cytoskeleton organization; IC:BHF-UCL.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
672Q9C3Y4    193   RHOA_EMENI GTP-binding protein rhoA OS=194 / ...1676e-19     85.5     29     54GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
673P41918    221   RANA1_TOBAC GTP-binding nuclear protein Ran-A...1586e-19     85.9     30     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
674P79735    215   RAN_DANRE GTP-binding nuclear protein Ran OS=...1586e-19     85.5     29     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
675P38548    221   RAN_VICFA GTP-binding nuclear protein Ran/TC4...1586e-19     85.9     30     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
676P33519    212   RAN_DICDI GTP-binding nuclear protein Ran OS=...1647e-19     85.5     30     52GO:0005813; C:centrosome; IDA:dictyBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
677P41919    221   RANB1_TOBAC GTP-binding nuclear protein Ran-B...1587e-19     85.9     30     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
678Q8H156    221   RAN3_ARATH GTP-binding nuclear protein Ran-3 ...1587e-19     85.5     30     52GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0009506; C:plasmodesma; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:TAIR.
GO:0006606; P:protein import into nucleus; TAS:TAIR.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
679P38543    226   RAN_GIAIN GTP-binding nuclear protein Ran OS=...1668e-19     85.5     31     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
680Q29HY3    191   CDC42_DROPS Cdc42 homolog OS=Drosophila pseud...1688e-19     85.1     29     51GO:0005912; C:adherens junction; ISS:UniProtKB.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0045185; P:maintenance of protein location; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045860; P:positive regulation of protein kinase activity; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
681P40793    191   CDC42_DROME Cdc42 homolog OS=Drosophila melan...1688e-19     85.1     29     51GO:0005912; C:adherens junction; IDA:UniProtKB.::GO:0030424; C:axon; IDA:FlyBase.::GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0030426; C:growth cone; IDA:FlyBase.::GO:0005634; C:nucleus; IDA:FlyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0016028; C:rhabdomere; IMP:FlyBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; NAS:FlyBase.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0030041; P:actin filament polymerization; IMP:FlyBase.::GO:0060446; P:branching involved in open tracheal system development; IMP:FlyBase.::GO:0030031; P:cell projection assembly; IMP:FlyBase.::GO:0007349; P:cellularization; TAS:FlyBase.::GO:0030866; P:cortical actin cytoskeleton organization; IMP:FlyBase.::GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0046843; P:dorsal appendage formation; IMP:FlyBase.::GO:0045200; P:establishment of neuroblast polarity; IMP:FlyBase.::GO:0035099; P:hemocyte migration; IMP:FlyBase.::GO:0035318; P:imaginal disc-derived wing hair outgrowth; IMP:FlyBase.::GO:0007254; P:JNK cascade; TAS:FlyBase.::GO:0030011; P:maintenance of cell polarity; IMP:FlyBase.::GO:0045185; P:maintenance of protein location; IMP:UniProtKB.::GO:0008045; P:motor axon guidance; IMP:FlyBase.::GO:0007274; P:neuromuscular synaptic transmission; IGI:FlyBase.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0045860; P:positive regulation of protein kinase activity; IMP:UniProtKB.::GO:0030833; P:regulation of actin filament polymerization; IDA:FlyBase.::GO:0050770; P:regulation of axonogenesis; IGI:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0008582; P:regulation of synaptic growth at neuromuscular junction; IDA:FlyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0007396; P:suture of dorsal opening; TAS:FlyBase.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:FlyBase.::GO:0042060; P:wound healing; IMP:FlyBase.
682P34443    207   RHEB1_CAEEL GTP-binding protein Rheb homolog ...1648e-19     85.1     32     57GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0040011; P:locomotion; IMP:WormBase.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
683P41916    221   RAN1_ARATH GTP-binding nuclear protein Ran-1 ...1589e-19     85.5     30     52GO:0048046; C:apoplast; IDA:TAIR.::GO:0005618; C:cell wall; IDA:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006606; P:protein import into nucleus; TAS:TAIR.::GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
684P35295    233   RAB20_MOUSE Ras-related protein Rab-20 OS=Mus...1169e-19     85.5     38     60GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
685Q16YG0    191   CDC42_AEDAE Cdc42 homolog OS=Aedes aegypti (Y...1681e-18     84.7     29     51GO:0005912; C:adherens junction; ISS:UniProtKB.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0045185; P:maintenance of protein location; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045860; P:positive regulation of protein kinase activity; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
686Q5R6S2    199   DIRA2_PONAB GTP-binding protein Di-Ras2 OS=Po...1611e-18     84.7     32     52GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
687Q9VND8    182   RHEB_DROME GTP-binding protein Rheb homolog O...1621e-18     84.3     35     56GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:FlyBase.
GO:0016049; P:cell growth; IMP:FlyBase.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:FlyBase.::GO:0030307; P:positive regulation of cell growth; TAS:FlyBase.::GO:0045793; P:positive regulation of cell size; IMP:FlyBase.::GO:0090070; P:positive regulation of ribosome biogenesis; IMP:FlyBase.::GO:0045727; P:positive regulation of translation; IMP:FlyBase.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:FlyBase.::GO:0042594; P:response to starvation; IEP:FlyBase.::GO:0042254; P:ribosome biogenesis; IDA:FlyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
688Q17031    191   CDC42_ANOGA Cdc42 homolog OS=Anopheles gambia...1681e-18     84.7     29     51GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
689Q74ZA9    214   GSP1_ASHGO GTP-binding nuclear protein GSP1/R...1581e-18     85.1     30     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
690Q54FK8    202   RABM_DICDI Ras-related protein RabM OS=Dictyo...1771e-18     84.7     28     50GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
691Q17QI8    236   RHOV_BOVIN Rho-related GTP-binding protein Rh...1892e-18     84.7     28     49GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
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