Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFL005W
Length:
215
Number of sequences:
5887
Description:
YFL005W SEC4 SGDID:S000001889, Chr VI from 130334-130981, Genome Release 64-1-1, Verified ORF, "Rab family GTPase essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
631Q9PSX7    193   RHOC_CHICK Rho-related GTP-binding protein Rh...1661e-19     87.4     28     52GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0043297; P:apical junction assembly; ISS:UniProtKB.::GO:0033205; P:cell cycle cytokinesis; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
632Q5RCK9    193   RHOC_PONAB Rho-related GTP-binding protein Rh...1661e-19     87     28     53GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0043297; P:apical junction assembly; ISS:UniProtKB.::GO:0033205; P:cell cycle cytokinesis; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
633Q62159    193   RHOC_MOUSE Rho-related GTP-binding protein Rh...1661e-19     87     28     53GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0043297; P:apical junction assembly; IDA:UniProtKB.::GO:0033205; P:cell cycle cytokinesis; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
634P08134    193   RHOC_HUMAN Rho-related GTP-binding protein Rh...1661e-19     87     28     53GO:0032154; C:cleavage furrow; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IMP:UniProtKB.
GO:0043297; P:apical junction assembly; IDA:UniProtKB.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0033205; P:cell cycle cytokinesis; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
635Q1RMJ6    193   RHOC_BOVIN Rho-related GTP-binding protein Rh...1661e-19     87     28     53GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0043297; P:apical junction assembly; ISS:UniProtKB.::GO:0033205; P:cell cycle cytokinesis; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
636P34726    193   RAS2_PHYPO Ras-like protein 2 OS=Physarum pol...1651e-19     87     33     58GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
637P32836    220   GSP2_YEAST GTP-binding nuclear protein GSP2/C...1721e-19     87.4     30     53GO:0005634; C:nucleus; IGI:SGD.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IGI:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0006997; P:nucleus organization; IGI:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
638P38976    192   RAS2_HYDVU Ras-like protein RAS2 OS=Hydra vul...1512e-19     86.7     34     56GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
639P38546    221   RAN1_SOLLC GTP-binding nuclear protein Ran1 O...1742e-19     87     30     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
640P01120    322   RAS2_YEAST Ras-like protein 2 OS=Saccharomyce...1532e-19     87.8     32     56GO:0005886; C:plasma membrane; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.
GO:0005525; F:GTP binding; IDA:SGD.::GO:0003924; F:GTPase activity; TAS:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007190; P:activation of adenylate cyclase activity; TAS:SGD.::GO:0030437; P:ascospore formation; IMP:SGD.::GO:0000411; P:positive regulation of transcription by galactose; IMP:SGD.::GO:0007124; P:pseudohyphal growth; IMP:SGD.::GO:0007265; P:Ras protein signal transduction; TAS:SGD.::GO:0032880; P:regulation of protein localization; IMP:SGD.::GO:0001302; P:replicative cell aging; IMP:SGD.
641P38547    221   RAN2_SOLLC GTP-binding nuclear protein Ran2 O...1743e-19     87     30     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
642Q9D0P8    186   IFT27_MOUSE Intraflagellar transport protein ...1743e-19     86.3     33     52
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
643Q9HE04    200   RHO5_SCHPO GTP-binding protein rho5 OS=Schizo...1723e-19     86.3     28     55GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0031520; C:plasma membrane of cell tip; IC:PomBase.
GO:0005525; F:GTP binding; IC:PomBase.::GO:0003924; F:GTPase activity; TAS:PomBase.
GO:0030100; P:regulation of endocytosis; ISS:PomBase.::GO:0032995; P:regulation of fungal-type cell wall biogenesis; IMP:PomBase.::GO:0007264; P:small GTPase mediated signal transduction; IC:PomBase.
644P34149    192   RACC_DICDI Rho-related protein racC OS=Dictyo...1693e-19     86.3     29     52GO:0031252; C:cell leading edge; IDA:dictyBase.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IDA:dictyBase.::GO:0019901; F:protein kinase binding; IPI:dictyBase.
GO:0016477; P:cell migration; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0045184; P:establishment of protein localization; IMP:dictyBase.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; IMP:dictyBase.::GO:0030838; P:positive regulation of actin filament polymerization; IDA:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
645Q8R367    199   RERG_MOUSE Ras-related and estrogen-regulated...1693e-19     86.3     34     57GO:0016020; C:membrane; IEA:InterPro.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
646P54765    209   RAN1A_LOTJA GTP-binding nuclear protein Ran1A...1583e-19     86.3     30     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
647P52301    216   RAN_XENLA GTP-binding nuclear protein Ran OS=...1583e-19     86.7     29     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
648Q6GL85    216   RAN_XENTR GTP-binding nuclear protein Ran OS=...1583e-19     86.7     29     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
649Q9BW83    186   IFT27_HUMAN Intraflagellar transport protein ...1743e-19     85.9     34     51GO:0030992; C:intraflagellar transport particle B; ISS:BHF-UCL.::GO:0009434; C:microtubule-based flagellum; ISS:BHF-UCL.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
650P54766    209   RAN1B_LOTJA GTP-binding nuclear protein Ran1B...1583e-19     86.3     30     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
651P62828    216   RAN_RAT GTP-binding nuclear protein Ran OS=Ra...1584e-19     86.3     29     53GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
652Q5R556    216   RAN_PONAB GTP-binding nuclear protein Ran OS=...1584e-19     86.3     29     53GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
653P62827    216   RAN_MOUSE GTP-binding nuclear protein Ran OS=...1584e-19     86.3     29     53GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.
GO:0030036; P:actin cytoskeleton organization; IMP:MGI.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0034629; P:cellular protein complex localization; IMP:MGI.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006606; P:protein import into nucleus; IDA:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
654Q4R4M9    216   RAN_MACFA GTP-binding nuclear protein Ran OS=...1584e-19     86.3     29     53GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
655P62826    216   RAN_HUMAN GTP-binding nuclear protein Ran OS=...1584e-19     86.3     29     53GO:0005829; C:cytosol; TAS:Reactome.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005643; C:nuclear pore; NAS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0050681; F:androgen receptor binding; NAS:UniProtKB.::GO:0003682; F:chromatin binding; TAS:UniProtKB.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; TAS:UniProtKB.::GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.
GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006259; P:DNA metabolic process; TAS:UniProtKB.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0007067; P:mitosis; TAS:UniProtKB.::GO:0007052; P:mitotic spindle organization; TAS:UniProtKB.::GO:0032092; P:positive regulation of protein binding; IDA:BHF-UCL.::GO:0045893; P:positive regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0006611; P:protein export from nucleus; NAS:UniProtKB.::GO:0006405; P:RNA export from nucleus; NAS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0046796; P:viral genome transport in host cell; TAS:Reactome.::GO:0019058; P:viral infectious cycle; TAS:Reactome.
656P62825    216   RAN_CANFA GTP-binding nuclear protein Ran OS=...1584e-19     86.3     29     53GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
657Q3T054    216   RAN_BOVIN GTP-binding nuclear protein Ran OS=...1584e-19     86.3     29     53GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
658Q9JJL4    205   RHOQ_RAT Rho-related GTP-binding protein RhoQ...1694e-19     86.3     29     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
659Q8R527    205   RHOQ_MOUSE Rho-related GTP-binding protein Rh...1694e-19     86.3     29     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:MGI.
GO:0030866; P:cortical actin cytoskeleton organization; IMP:BHF-UCL.::GO:0090005; P:negative regulation of establishment of protein localization in plasma membrane; IDA:BHF-UCL.::GO:0046325; P:negative regulation of glucose import; IC:BHF-UCL.::GO:0008360; P:regulation of cell shape; IDA:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
660Q7ZZX9    215   RAN_CARAU GTP-binding nuclear protein Ran OS=...1584e-19     86.3     29     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
661Q09914    202   RHO1_SCHPO GTP-binding protein rho1 OS=Schizo...1794e-19     86.3     28     54GO:0000935; C:barrier septum; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0031234; C:extrinsic to internal side of plasma membrane; NAS:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0030427; C:site of polarized growth; TAS:PomBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:PomBase.::GO:0060583; P:regulation of actin cortical patch localization; IGI:PomBase.::GO:0032956; P:regulation of actin cytoskeleton organization; IMP:PomBase.::GO:0032949; P:regulation of alpha-glucan biosynthetic process; IMP:PomBase.::GO:0032955; P:regulation of barrier septum assembly; IMP:PomBase.::GO:0090334; P:regulation of cell wall (1->3)-beta-D-glucan biosynthetic process; TAS:PomBase.::GO:0030100; P:regulation of endocytosis; ISS:PomBase.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IMP:PomBase.::GO:0007266; P:Rho protein signal transduction; TAS:PomBase.
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