Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFL005W
Length:
215
Number of sequences:
5887
Description:
YFL005W SEC4 SGDID:S000001889, Chr VI from 130334-130981, Genome Release 64-1-1, Verified ORF, "Rab family GTPase essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q06AU7    201   RAB1B_PIG Ras-related protein Rab-1B OS=Sus s...2006e-69     216     51     72GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
62Q9FPJ4    202   RAD2B_ARATH Ras-related protein RABD2b OS=Ara...2007e-69     216     52     71GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0009860; P:pollen tube growth; IGI:TAIR.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
63Q9SEH3    202   RAD2C_ARATH Ras-related protein RABD2c OS=Ara...2001e-68     215     52     71GO:0005829; C:cytosol; IDA:TAIR.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0009555; P:pollen development; IMP:TAIR.::GO:0009860; P:pollen tube growth; IGI:TAIR.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
64Q9ZRE2    205   RABD1_ARATH Ras-related protein RABD1 OS=Arab...2042e-68     215     52     72GO:0000139; C:Golgi membrane; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0032588; C:trans-Golgi network membrane; IDA:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0030742; F:GTP-dependent protein binding; IPI:TAIR.::GO:0080115; F:myosin XI tail binding; IPI:TAIR.
GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
65P31584    203   YPTV1_VOLCA GTP-binding protein yptV1 OS=Volv...1712e-68     214     57     78GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
66P35281    200   RAB10_RAT Ras-related protein Rab-10 OS=Rattu...2033e-68     214     52     72GO:0005624; C:membrane fraction; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0005802; C:trans-Golgi network; IDA:RGD.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0071236; P:cellular response to antibiotic; IEP:RGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
67Q01890    201   YPT1_PHYIN Ras-like GTP-binding protein YPT1 ...2022e-67     212     51     71GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
68P34139    202   RAB1A_DICDI Ras-related protein Rab-1A OS=Dic...2002e-67     212     51     72GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
69P16976    208   YPTM1_MAIZE GTP-binding protein YPTM1 OS=Zea ...1674e-66     209     56     76GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
70Q54NU2    204   RAB1D_DICDI Ras-related protein Rab-1D OS=Dic...1728e-66     208     56     77GO:0045335; C:phagocytic vesicle; IDA:dictyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
71P34140    206   RAB1B_DICDI Ras-related protein Rab-1B OS=Dic...1678e-64     203     55     75GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
72P01123    206   YPT1_YEAST GTP-binding protein YPT1 OS=Saccha...2021e-63     202     49     69GO:0005789; C:endoplasmic reticulum membrane; IDA:SGD.::GO:0000139; C:Golgi membrane; IDA:SGD.::GO:0005795; C:Golgi stack; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0000407; C:pre-autophagosomal structure; IDA:SGD.::GO:0005802; C:trans-Golgi network; IDA:SGD.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:SGD.::GO:0000149; F:SNARE binding; IDA:SGD.
GO:0090114; P:COPII-coated vesicle budding; IMP:SGD.::GO:0032258; P:CVT pathway; IMP:SGD.::GO:0034498; P:early endosome to Golgi transport; IMP:SGD.::GO:0032456; P:endocytic recycling; IMP:SGD.::GO:0048194; P:Golgi vesicle budding; IGI:SGD.::GO:0048211; P:Golgi vesicle docking; IMP:SGD.::GO:0016236; P:macroautophagy; IMP:SGD.::GO:0006461; P:protein complex assembly; IDA:SGD.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IMP:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0035494; P:SNARE complex disassembly; IMP:SGD.
73Q4R4R9    220   RAB3A_MACFA Ras-related protein Rab-3A OS=Mac...1712e-61     197     53     75GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
74P20336    220   RAB3A_HUMAN Ras-related protein Rab-3A OS=Hom...1712e-61     197     53     75GO:0060201; C:clathrin sculpted acetylcholine transport vesicle membrane; TAS:Reactome.::GO:0061202; C:clathrin sculpted gamma-aminobutyric acid transport vesicle membrane; TAS:Reactome.::GO:0060203; C:clathrin sculpted glutamate transport vesicle membrane; TAS:Reactome.::GO:0070083; C:clathrin sculpted monoamine transport vesicle membrane; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0008021; C:synaptic vesicle; TAS:ProtInc.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IMP:UniProtKB.
GO:0014047; P:glutamate secretion; TAS:Reactome.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
75P63012    220   RAB3A_RAT Ras-related protein Rab-3A OS=Rattu...1713e-61     197     53     75GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0043234; C:protein complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0008021; C:synaptic vesicle; IDA:RGD.::GO:0019717; C:synaptosome; IDA:RGD.
GO:0001671; F:ATPase activator activity; IDA:RGD.::GO:0051117; F:ATPase binding; IDA:RGD.::GO:0005525; F:GTP binding; IDA:RGD.::GO:0051020; F:GTPase binding; IPI:RGD.::GO:0008022; F:protein C-terminus binding; IPI:RGD.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032482; P:Rab protein signal transduction; IC:RGD.
76Q06AU3    220   RAB3A_PIG Ras-related protein Rab-3A OS=Sus s...1713e-61     197     53     75GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0008021; C:synaptic vesicle; ISS:AgBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; ISS:AgBase.
GO:0007409; P:axonogenesis; ISS:AgBase.::GO:0030324; P:lung development; ISS:AgBase.::GO:0048790; P:maintenance of presynaptic active zone structure; ISS:AgBase.::GO:0007005; P:mitochondrion organization; ISS:AgBase.::GO:0007274; P:neuromuscular synaptic transmission; ISS:AgBase.::GO:0009791; P:post-embryonic development; ISS:AgBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0031630; P:regulation of synaptic vesicle fusion to presynaptic membrane; ISS:AgBase.::GO:0003016; P:respiratory system process; ISS:AgBase.::GO:0051602; P:response to electrical stimulus; ISS:AgBase.::GO:0050975; P:sensory perception of touch; ISS:AgBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016079; P:synaptic vesicle exocytosis; ISS:AgBase.::GO:0016188; P:synaptic vesicle maturation; ISS:AgBase.
77P63011    220   RAB3A_MOUSE Ras-related protein Rab-3A OS=Mus...1713e-61     197     53     75GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0008021; C:synaptic vesicle; IDA:MGI.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007409; P:axonogenesis; IMP:MGI.::GO:0030324; P:lung development; IMP:MGI.::GO:0048790; P:maintenance of presynaptic active zone structure; IMP:MGI.::GO:0007005; P:mitochondrion organization; IMP:MGI.::GO:0007274; P:neuromuscular synaptic transmission; IMP:MGI.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0031630; P:regulation of synaptic vesicle fusion to presynaptic membrane; IMP:MGI.::GO:0003016; P:respiratory system process; IMP:MGI.::GO:0051602; P:response to electrical stimulus; IMP:MGI.::GO:0050975; P:sensory perception of touch; IMP:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016079; P:synaptic vesicle exocytosis; IMP:MGI.::GO:0016188; P:synaptic vesicle maturation; IMP:MGI.
78P11023    220   RAB3A_BOVIN Ras-related protein Rab-3A OS=Bos...1713e-61     197     53     75GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0008021; C:synaptic vesicle; ISS:AgBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; ISS:AgBase.
GO:0007409; P:axonogenesis; ISS:AgBase.::GO:0030324; P:lung development; ISS:AgBase.::GO:0048790; P:maintenance of presynaptic active zone structure; ISS:AgBase.::GO:0007005; P:mitochondrion organization; ISS:AgBase.::GO:0007274; P:neuromuscular synaptic transmission; ISS:AgBase.::GO:0009791; P:post-embryonic development; ISS:AgBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0031630; P:regulation of synaptic vesicle fusion to presynaptic membrane; ISS:AgBase.::GO:0003016; P:respiratory system process; ISS:AgBase.::GO:0051602; P:response to electrical stimulus; ISS:AgBase.::GO:0050975; P:sensory perception of touch; ISS:AgBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016079; P:synaptic vesicle exocytosis; ISS:AgBase.::GO:0016188; P:synaptic vesicle maturation; ISS:AgBase.
79Q39570    213   YPTC4_CHLRE GTP-binding protein YPTC4 OS=Chla...2112e-60     194     44     63GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
80Q63942    219   RAB3D_RAT GTP-binding protein Rab-3D OS=Rattu...2102e-60     194     43     66GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0030133; C:transport vesicle; IDA:RGD.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0051020; F:GTPase binding; IPI:RGD.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
81P35276    219   RAB3D_MOUSE Ras-related protein Rab-3D OS=Mus...2103e-60     194     43     65GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0042588; C:zymogen granule; IDA:MGI.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0018125; P:peptidyl-cysteine methylation; IDA:MGI.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0017157; P:regulation of exocytosis; IDA:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
82P25228    220   RAB3_DROME Ras-related protein Rab-3 OS=Droso...2051e-59     193     46     70GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0048786; C:presynaptic active zone; IDA:FlyBase.::GO:0008021; C:synaptic vesicle; NAS:FlyBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0048790; P:maintenance of presynaptic active zone structure; IMP:FlyBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
83P36863    213   YPTV4_VOLCA GTP-binding protein yptV4 OS=Volv...2111e-59     192     44     63GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
84Q8K386    212   RAB15_MOUSE Ras-related protein Rab-15 OS=Mus...2123e-59     191     45     67GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
85O95716    219   RAB3D_HUMAN Ras-related protein Rab-3D OS=Hom...1744e-59     191     49     74GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
86P35289    212   RAB15_RAT Ras-related protein Rab-15 OS=Rattu...2129e-59     190     44     67GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; TAS:RGD.
GO:0007269; P:neurotransmitter secretion; TAS:RGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
87P20337    219   RAB3B_HUMAN Ras-related protein Rab-3B OS=Hom...1742e-58     190     50     74GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
88Q9TVU5    220   RAB1_THEPA Ras-related protein Rab-1 OS=Theil...1942e-58     190     47     72GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
89Q1RMR4    212   RAB15_BOVIN Ras-related protein Rab-15 OS=Bos...2122e-58     189     44     67GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
90Q5U316    201   RAB35_RAT Ras-related protein Rab-35 OS=Rattu...1682e-58     189     53     75GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
91Q6PHN9    201   RAB35_MOUSE Ras-related protein Rab-35 OS=Mus...1682e-58     189     53     75GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:MGI.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
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