Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFL005W
Length:
215
Number of sequences:
5887
Description:
YFL005W SEC4 SGDID:S000001889, Chr VI from 130334-130981, Genome Release 64-1-1, Verified ORF, "Rab family GTPase essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
601Q86L51    205   RAPB_DICDI Ras-related protein rapB OS=Dictyo...1927e-20     88.2     34     54GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
602Q0VCN3    186   IFT27_BOVIN Intraflagellar transport protein ...1747e-20     87.8     35     53
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
603Q8TAI7    183   REBL1_HUMAN GTPase RhebL1 OS=Homo sapiens (Hu...1637e-20     87.8     34     56GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0031929; P:TOR signaling cascade; IMP:UniProtKB.
604B4PUP5    189   RAS1_DROYA Ras-like protein 1 OS=Drosophila y...1558e-20     87.8     32     57GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
605P83831    189   RAS1_DROSI Ras-like protein 1 OS=Drosophila s...1558e-20     87.8     32     57GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
606B4HKC7    189   RAS1_DROSE Ras-like protein 1 OS=Drosophila s...1558e-20     87.8     32     57GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
607P08646    189   RAS1_DROME Ras-like protein 1 OS=Drosophila m...1558e-20     87.8     32     57GO:0005886; C:plasma membrane; IDA:FlyBase.
GO:0005525; F:GTP binding; NAS:UniProtKB.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0008595; P:anterior/posterior axis specification, embryo; TAS:FlyBase.::GO:0006916; P:anti-apoptosis; NAS:FlyBase.::GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0001708; P:cell fate specification; TAS:FlyBase.::GO:0016049; P:cell growth; TAS:FlyBase.::GO:0030381; P:chorion-containing eggshell pattern formation; IMP:FlyBase.::GO:0007391; P:dorsal closure; TAS:FlyBase.::GO:0035088; P:establishment or maintenance of apical/basal cell polarity; IMP:FlyBase.::GO:0007455; P:eye-antennal disc morphogenesis; IMP:FlyBase.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:FlyBase.::GO:0007369; P:gastrulation; IMP:FlyBase.::GO:0007507; P:heart development; NAS:FlyBase.::GO:0035099; P:hemocyte migration; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0002168; P:instar larval development; IMP:FlyBase.::GO:0072002; P:Malpighian tubule development; IMP:FlyBase.::GO:0046673; P:negative regulation of compound eye retinal cell programmed cell death; IMP:FlyBase.::GO:0007309; P:oocyte axis specification; IMP:FlyBase.::GO:0007422; P:peripheral nervous system development; IMP:FlyBase.::GO:0030307; P:positive regulation of cell growth; TAS:FlyBase.::GO:0008284; P:positive regulation of cell proliferation; IMP:FlyBase.::GO:0046534; P:positive regulation of photoreceptor cell differentiation; IMP:FlyBase.::GO:0007428; P:primary branching, open tracheal system; TAS:FlyBase.::GO:0006606; P:protein import into nucleus; IGI:FlyBase.::GO:0008361; P:regulation of cell size; IMP:FlyBase.::GO:0045610; P:regulation of hemocyte differentiation; IMP:FlyBase.::GO:0040014; P:regulation of multicellular organism growth; IMP:FlyBase.::GO:0045500; P:sevenless signaling pathway; TAS:FlyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0048865; P:stem cell fate commitment; IMP:FlyBase.::GO:0072089; P:stem cell proliferation; IMP:FlyBase.::GO:0008293; P:torso signaling pathway; TAS:FlyBase.::GO:0007426; P:tracheal outgrowth, open tracheal system; IMP:FlyBase.
608P83832    189   RAS1_DROMA Ras-like protein 1 OS=Drosophila m...1558e-20     87.8     32     57GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
609B3NZR4    189   RAS1_DROER Ras-like protein 1 OS=Drosophila e...1558e-20     87.8     32     57GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
610B3M185    189   RAS1_DROAN Ras-like protein 1 OS=Drosophila a...1558e-20     87.8     32     57GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
611P15064    189   RASG_DICDI Ras-like protein rasG OS=Dictyoste...1658e-20     87.8     34     57GO:0045335; C:phagocytic vesicle; IDA:dictyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IDA:dictyBase.::GO:0003924; F:GTPase activity; IDA:dictyBase.::GO:0005515; F:protein binding; IPI:dictyBase.
GO:0007190; P:activation of adenylate cyclase activity; IGI:dictyBase.::GO:0032861; P:activation of Rap GTPase activity; IMP:dictyBase.::GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0000902; P:cell morphogenesis; IMP:dictyBase.::GO:0008283; P:cell proliferation; IGI:dictyBase.::GO:0031589; P:cell-substrate adhesion; IMP:dictyBase.::GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0007188; P:G-protein signaling, coupled to cAMP nucleotide second messenger; IMP:dictyBase.::GO:0008284; P:positive regulation of cell proliferation; IMP:dictyBase.::GO:0030828; P:positive regulation of cGMP biosynthetic process; IMP:dictyBase.::GO:0031284; P:positive regulation of guanylate cyclase activity; IMP:dictyBase.::GO:0050927; P:positive regulation of positive chemotaxis; IMP:dictyBase.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:dictyBase.::GO:0007265; P:Ras protein signal transduction; IDA:dictyBase.::GO:0046586; P:regulation of calcium-dependent cell-cell adhesion; IMP:dictyBase.::GO:0001932; P:regulation of protein phosphorylation; IMP:dictyBase.
612B4LY29    189   RAS1_DROVI Ras-like protein 1 OS=Drosophila v...1558e-20     87.8     32     57GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
613Q12526    212   RAS_EMENI Ras-like protein OS=194 / M139) (As...1518e-20     88.2     33     56GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
614P35290    203   RAB24_MOUSE Ras-related protein Rab-24 OS=Mus...1659e-20     87.8     33     53GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:MGI.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
615O93856    209   RAS_LACBI Ras-like protein OS=bicolor). GN= ...1519e-20     88.2     33     56GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
616Q7F7I7    221   RAN1_ORYSJ GTP-binding nuclear protein Ran-1 ...1749e-20     88.2     30     50
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
617A2WSI7    221   RAN1_ORYSI GTP-binding nuclear protein Ran-1 ...1749e-20     88.2     30     50
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
618Q96A58    199   RERG_HUMAN Ras-related and estrogen-regulated...1679e-20     87.8     34     58GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0016020; C:membrane; IEA:InterPro.::GO:0005634; C:nucleus; IDA:HPA.
GO:0030331; F:estrogen receptor binding; NAS:UniProtKB.::GO:0019003; F:GDP binding; TAS:UniProtKB.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0009725; P:response to hormone stimulus; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
619Q6Z7L8    197   RAC7_ORYSJ Rac-like GTP-binding protein 7 OS=...1741e-19     87.8     29     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
620Q38903    201   RAC2_ARATH Rac-like GTP-binding protein ARAC2...1671e-19     87.8     31     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
621Q8K586    216   RANT_RAT GTP-binding nuclear protein Ran, tes...1681e-19     87.8     30     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
622Q550Q4    185   RHEB_DICDI GTP-binding protein Rheb homolog O...1541e-19     87.4     36     56GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
623P62071    204   RRAS2_MOUSE Ras-related protein R-Ras2 OS=Mus...1511e-19     87.8     33     59GO:0005622; C:intracellular; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.
GO:0030335; P:positive regulation of cell migration; IGI:MGI.::GO:0007265; P:Ras protein signal transduction; IDA:MGI.
624P62070    204   RRAS2_HUMAN Ras-related protein R-Ras2 OS=Hom...1511e-19     87.8     33     59GO:0005783; C:endoplasmic reticulum; NAS:ProtInc.::GO:0005886; C:plasma membrane; NAS:ProtInc.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct.
625P34729    189   RAS1_PHYPO Ras-like protein 1 OS=Physarum pol...1621e-19     87.4     34     57GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
626P70425    217   RIT2_MOUSE GTP-binding protein Rit2 OS=Mus mu...1771e-19     87.8     32     54GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
627Q0VCJ7    199   RERG_BOVIN Ras-related and estrogen-regulated...1671e-19     87.4     34     58GO:0016020; C:membrane; IEA:InterPro.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
628P22280    205   RAS3_MUCCL Ras-like protein 3 OS=lusitanicus)...1511e-19     87.4     32     54GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
629Q7GD79    221   RAN2_ORYSJ GTP-binding nuclear protein Ran-2 ...1581e-19     87.8     30     52
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
630A2Y7R5    221   RAN2_ORYSI GTP-binding nuclear protein Ran-2 ...1581e-19     87.8     30     52
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
631Q9PSX7    193   RHOC_CHICK Rho-related GTP-binding protein Rh...1661e-19     87.4     28     52GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0043297; P:apical junction assembly; ISS:UniProtKB.::GO:0033205; P:cell cycle cytokinesis; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
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